Wyniki wyszukiwania - Biblioteka Nauki

1

THE IMPACT OF WINGATE AND PROGRESSIVE TESTS ON HOMOCYSTEINE, VITAMIN B6, B12 AND FOLIC ACID LEVELS IN ATHLETES’ BLOOD

100%

Murawska-Ciałowicz E.

Central European Journal of Sport Sciences and Medicine

|

2014

|

tom 8

|

nr 4

5-17

EN

Homocysteine is an indirect metabolite of methionine metabolism, as well as of creatinine, and it plays an important role in many biochemical processes. Physical effort modifies homocysteine concentration in the blood, as well as the substances taking part in its metabolism. The aim of the study was to assess the influence of intensive efforts of diverse energy changes on the concentrations of homocysteine and the vitamins involved in its metabolism – vit. B6, vit. B12 and folic acid. In the study athletes performed Wingate and progressive test. Before and after tests homocysteine, vitamins B6, B12 and folic acid and creatinine were assayed. Concentration of homocysteine, vit. B12 and creatinine in the blood increased after both tests. Concentration of vit. B6 decreased and folic acid increased after Wingate test while they did not change after a progressive test. Homocysteine concentration negatively correlated with folic acid but positively with creatinine concentration in the blood, as well as with LBM. Regardless of its duration and energetic changes, intensive effort leads to an increase in homocysteine concentration. Correlation of homocysteine with creatinine and the LBM suggest that people with bigger muscle mass can have higher homocysteine concentration in the blood.

2

Vitamin B6 and its metabolite reveal radical scavenging activity at basic pH

100%

Gliszczynska-Swiglo A. , Szymusiak H.

Polish Journal of Food and Nutrition Sciences

|

2007

|

tom 57

|

nr 4[A]

163-167

EN

In the present study, the pH-dependent radical-scavenging activities, in the TEAC (Trolox equivalent antioxidant capacity) assay, of pyridoxine (PN), pyridoxal (PL), pyridoxamine (PM) (vitamin B6 forms) and their main metabolite 4-pyridoxic acid (PA) was determined. For all compounds, the increase in the TEAC values with increasing pH of the medium from value 7 to 9 was observed. The order of radical-scavenging activity was found as follows: PN>PM>PL>PA and it was confirmed by their oxidative potentials measured using cyclic and square-wave voltammetry. Quantitative relationship between experimental radical-scavenging activity and calculated bond dissociation energy values (BDE) was found suggesting hydrogen atom donation as the main mechanism of radical-scavenging activity of vitamin B6 and PA. The results of the present study suggest that vitamin B6 may contribute to the total antioxidant capacity of antioxidants present in human body especially at basic conditions.

PL

Zbadano wpływ pH na aktywność przeciwrodnikową PN, PL, PM i PA, mierzoną w teście TEAC (trolox equivalent antioxidant capacity). Dla wszystkich badanych związków zaobserwowano wzrost wartości TEAC w zakresie pH 7-9. Aktywność przeciwrodnikowa malała w kolejności PN>PM>PL>PA, co zostało potwierdzone poprzez wartości potencjałów utleniania wyznaczone metodami woltamperometrii cyklicznej i fali prostokątnej. Stwierdzono istotną współzależność pomiędzy doświadczalnie wyznaczonymi wartościami aktywności przeciwrodnikowej lub potencjałami utleniania a teoretycznie obliczonymi wartościami energii dysocjacji grupy OH (BDE), co sugeruje, że obniżenie energii odszczepiania atomu wodoru z grupy (fenolowej) OH witaminy B6 i kwasu pirydoksynowego może wyjaśniać wzrost aktywności przeciwrodnikowej tych związków, obserwowany w środowisku zasadowym.

3

Evaluation for magnesium and vitamin B6 supplementation among Polish elite athletes

100%

Czaja J. , Lebiedzinska A. , Marszall M. , Szefer P.

Roczniki Państwowego Zakładu Higieny

|

2011

|

tom 62

|

nr 4

PL

Współczesny sport wyczynowy często wymaga od zawodników ogromnego wysiłku, który przekracza ich maksymalne możliwości fizyczne i umysłowe. Sportowcy często mają złe nawyki żywieniowe i spożywają suplementy diety zawierające magnez i witaminę B6 w celu uzupełnienia niedoborów żywieniowych. Celem badań było oznaczanie zawartości magnezu i witaminy B6 w całodziennych racjach pokarmowych sportowców wyczynowych w Polsce i ocena uzasadnienia suplementacji diety. Zawartość magnezu i witaminy B6 oznaczano w 62 zebranych i 12 odtworzonych całodziennych racjach pokarmowych profesjonalnych biegaczy. Do oznaczania magnezu i witaminy B6 wykorzystano odpowiednio metodę spektroskopii absorpcyjno atomowej i HPLC. Analizowane całodzienne racje pokarmowe kobiet dostarczały 256 ± 111 mg magnezu i 2,04 ± 0,63 mg witaminy B6, podczas gdy całodzienne racje pokarmowe mężczyzn dostarczały 284 ± 58 mg magnezu i 2,12 ± 0,68 mg witaminy B6. Analiza przeprowadzona z udziałem programu komputerowego wykazała 159-181% wyższą zawartość magnezu i witaminy B6 w porównaniu do wartości oznaczonych laboratoryjnie. Wyniki badań wykazały, że analizowane całodzienne racje pokarmowe sportowców dostarczały zbyt małych ilości magnezu, co może uzasadniać suplementację diety tym pierwiastkiem. Całodzienne racje pokarmowe pokrywały natomiast dzienne zapotrzebowanie (RDA) na witaminę B6, dlatego też suplementacja diety tym składnikiem nie była uzasadniona.

EN

Contemporary sport requires a lot of effort from sportsmen, frequently exceeding their maximum physical and mental efficiency. Athletes often report poor dietary habits and reach for magnesium and vitamin B supplements to avoid dietary deficiencies. The aim of this study was to determine magnesium and vitamin B6 content in daily food rations of Polish athletes and to verify the justification of diet supplementation. Magnesium and vitamin B6 concentrations were determined in 62 collected and 12 reconstructed daily food rations of elite Polish runners. Flame atomic absorption spectrmetry and HPLC methods were used for quantification of magnesium and vitamin B6, respectively. The analyzed female diets provided daily 256 ± 111 mg of magnesium and 2,04 ± 0.63 mg of vitamin B6 whereas male diets provided 284 ± 58 mg of magnesium and 2.12 ± 0,68 mg of vitamin B6. Computer analysis calculated 159-181% higher content of magnesium and vitamin B6 comparing to determined laboratory values. The results of this study indicate that in the analyzed daily food rations of athletes low magnesium intake was observed, thus diet supplementation with this mineral may be justified. Daily food rations fulfilled RDA for vitamin B6, thus supplementation with this vitamin was not justified.

4

Homocysteine and vitamin therapy in stroke prevention and treatment: a review

100%

Manolescu B. N. , Oprea E. , Farcasanu I. C. , Berteanu M. , Cercasov C.

Acta Biochimica Polonica

|

2010

|

tom 57

|

nr 4

467-477

EN

Homocysteine (Hcy), a sulfur amino acid, is the only direct precursor for l-methionine synthesis through a reaction that requires vitamin B12, representing a connection with "one-carbon" units metabolism. Hcy catabolism requires vitamin B6 and as a consequence, alteration in folic acid and B vitamins status impairs Hcy biotransformation. Numerous studies have indicated that Hcy is an independent risk factor for cardio- and cerebrovascular diseases. In the last decade, several clinical trials have investigated the possible correlation between the use of folic acid and vitamins B6 and B12 for lowering Hcy plasma concentration and the reduced risk of stroke or its recurrence. This review is aimed to present some aspects of Hcy biochemistry, as well as the mechanisms through which it exerts the toxic effects on the vascular endothelium. We also discuss the results of some of the clinical trials developed to investigate the beneficial effects of vitamin therapy in the prevention and management of stroke.

5

Effects of excess vitamin B6 intake on cerebral cortex neurons in rat: an ultrastructural study

100%

Demir R. , Acar G. , Tanriover G. , Seval Y. , Kayisli U. A. , Agar A.

Folia Histochemica et Cytobiologica

|

2005

|

tom 43

|

nr 3

6

Evaluation of vitamin C and vitamin B6 influence on the level of carnitine in plasma of healthy adults

84%

Jankowska M. , Horabik A. , Rutkowski B. , Ejsmont J. , Lysiak-Szydlowska W.

Polish Journal of Environmental Studies

|

2004

|

tom 13

|

nr Suppl.2, Part 1

EN

Efficiency of L-carnitine endogenous biosynthesis in humans depends on the presence of cofactors of numerous enzymatic reactions. Among others, the role of cofactor is played by vitamin C and vitamin B6. The objective of our study was to evaluate the influence of vitamins C and B6 stores on plasma carnitine level in healthy humans. The examined group consisted of 52 healthy volunteers. Total (TC) and free (FC) carnitine, ascorbic acid (AA) in plasma and indices of vitamin B6 in plasma and in erythrocytes were determined. Mean TC was 52.2 ± 10.7 mmol/1 and FC 44.4 ± 9.5 mmol/1. Mean AA was 0.4 ± 0.3 mg/dl. In 40% of examined group AA levels were out of the reference range. B6 indices in plasma and erythrocytes were 1.21 ± 0.23 and 1.42 ± 0.33, respectively. Vitamin C and vitamin B6 did not influence carnitine plasma levels, that confirms the marginal role of endogenous biosynthesis in the carnitine balance in healthy subjects. Moreover, a significant distribution of vitamin C deficiency was found in the evaluated population.

7

Vitamins B1, B2, B6 in raw and processed buckwheat sprouts

84%

Ornatowska A. , Penas E. , Frias J. , Vidal-Valverde C. , Piskula M. K.

Polish Journal of Food and Nutrition Sciences

|

2011

|

tom 61

|

nr Suppl.1

8

Effect of feed supplementation with alpha-ketoglutarate, combined with vitamin B6 or C, on the performance and haemoglobin and amino acid levels in growing rats

84%

Pierzynowski S. G. , Filip R. , Harrison A.

|

nr 2

EN

The aim of the study was to evaluate the influence of α-ketoglutarate (AKG), at pH 2 or 5, combined with vitamin B₆ (AKG 2B, AKG 5B) or C (AKG 2C, AKG 5C), on the performance and haemoglobin and amino acid levels in growing rats. Eighty rats were divided into 5 treatment groups and stayed on trial for 9 d (n=16) or 18 d (n=10). No significant differences in average daily gain (ADG), average daily feed intake (ADFI), or feed efficiency were seen between the dextrose-treated control group and the AKG treated groups. The highest ADG and ADFI were seen in the AKG 2B rats. The AKG 2B and AKG 2C treated rats had the highest Hb levels. The Hb levels were positively correlated with a better performance. The free glutamine (Glu) increased over time in all the groups. The arginine (Arg) levels significantly increased in the AKG 2B and AKG 5B groups. An increase in free Glu had a positive impact on the growth performance.

9

Overview of the role of vitamins and minerals on the kynurenine pathway in health and disease

67%

Majewski M. , Kozlowska A. , Thoene M. , Lepiarczyk E. , Grzegorzewski W. J.

Journal of Physiology and Pharmacology

|

2016

|

tom 67

|

nr 1

10

Homocysteine level in urine of autistic and healthy children

67%

Kaluzna-Czaplinska J. , Michalska M. , Rynkowski J.

Acta Biochimica Polonica

|

2011

|

tom 58

|

nr 1

EN

Homocysteine is an amino acid which plays several important roles in human physiology and is an important biomarker for possible deficiencies of various vitamins (vitamin B6 and B12, folic acid). In this work GC-MS method was used to determine the levels of homocysteine in the urine of autistic and healthy children. The levels of homocysteine in urine samples from 34 autistic and 21 healthy children were 2.36 ± 1.24 and 0.76 ± 0.31 (mmol∙mol-1 creatinine), respectively. The higher level of homocysteine in autistic children may indicate deficiencies of folic acid and vitamins B6 and B12 in nutrition of these children. The results of this work were taken into consideration in the nutrition of autistic children treated in the Navicula Centre of Diagnosis and Therapy of Autism in Łódź (Poland).

11

Pieczywo wzbogacone maka z nasion winogron zrodlem witamin grupy B

59%

Lebiedzinska A. , Marszalt M. , Sperra J. , Szefer P.

Bromatologia i Chemia Toksykologiczna

|

2006

|

tom 39

|

nr 2

121-125

12

Zapalenie nerwów obwodowych: etiologia, diagnostyka i leczenie

59%

Puk O.

Gabinet Prywatny

|

2022

|

tom 29 (280)

|

nr 01

19-29

EN

Peripheral neuropathy is a common condition, with diabetes, alcoholism, and Guillain-Barre syndrome accounting for approximately 90% of all cases. The heterogeneous mechanism of nerve damage, e.g. trauma, infection, metabolic disease, etc., and the heterogeneous nature of the affected nerve fibres result in a broad and complex spectrum of symptoms of neuropathy. However, most common symptom is pain, most often constant, strong sensations as burning, stinging, etc. In addition, paraesthesia, loss of superficial sensation, weakness of reflexes and muscle weakness may occur. Diagnostics is based primarily on the clinical evaluation of patients and a thorough history. Importantly, therapy must include causal treatment, e.g. antibiotic therapy, surgery for pressure / trauma, etc., and adequate pain management with coanalgesics such as opioids, tricyclic antidepressants, antiepileptic drugs, etc. Supplementation of vitamin B complex as a coanalgesic is of great benefit. B vitamins reduce pain in more than 75% of patients and have neuroprotective effects through decrease of inflammation. It should be remembered that good therapeutic effects are obtained by using combination drugs, e.g. tramadol with paracetamol, diclofenac with B vitamins or other pharmaceutics with vitamins B1, B6 and B12. The therapy should follow the "analgesic ladder". Treatment of neuropathic pain should be supervised by an appropriate specialist, e.g. a neurologist.

PL

Neuropatia nerwów obwodowych jest dolegliwością powszechnie występującą, a cukrzyca, alkoholizm i zespół Guillain-Barre odpowiadają za ok. 90% jej przypadków. Różnorodny mechanizm uszkodzenia nerwów, tj. uraz, infekcja, choroba metaboliczna itp. oraz różnorodny charakter dotkniętych włókien nerwowych są przyczyną szerokiego spektrum objawów neuropatii. Jednakże najczęściej dolegliwości bólowe są stałe, silne, odczuwane jako pieczenie, szczypanie, itp. Ponadto mogą wystąpić parestezje, zniesienie czucia powierzchownego, osłabienie odruchów oraz osłabienie siły mięśniowej.

13

Rozmieszczenie i wspolzaleznosci zawartosci witamin B6 i B12 w roznych czesciach lososi norweskich i baltyckich

59%

Lebiedzinska A. , Zbikowski R.

Roczniki Państwowego Zakładu Higieny

|

2007

|

tom 58

|

nr 2

417-422

PL

Ryby stanowią istotne źródło składników odżywczych, w tym witamin z grupy B. W niniejszej pracy oznaczano stężenie witamin B6 i cyjanokobalaminy w częściach łososi norweskich i bałtyckich pochodzących z rynku metodą wysokosprawnej chromatografii cieczowej (HPLC). W badaniach stwierdzono istotne korelacje (p<0,05; p<0,01; p<0,001) zawartości witamin B6 i B12 (cyjanokobalaminy) w badanych częściach łososi norweskich i bałtyckich.

EN

Fish constitute a major part of animal protein consumption in many countries of the world. Seafood are important source of a variety of nutrients, including vitamins B6 and B12. The concentration of vitamins B6 and B12 was determined in atlantic salmons obtained from commercial sources using a high-performance liquid chromatography (HPLC). In our study significant correlations (p<0,05, p<0,01 and p<0,001) for the concentration of vitamin B6 and cyanocobalamin between analyzed parts of atlantic salmons were observed.

14

Wplyw diety o zwiekszonej zawartosci witaminy B6 na wchlanianie aminokwasow w jelicie szczurow narazonych na karbaryl,propoksur i tiuram.Cz.1 Metionina

59%

Witkowska D. , Sedrowicz L. , Oledzka R.

Bromatologia i Chemia Toksykologiczna

|

1992

|

tom 25

|

nr 1

25-30

EN

Alimentary rations under test were found to be rich in fat. Fat energy proportional portion exceeded, as a rule, the recommended value by about 30%. At the same time, acidic composition of fat under test was wide of the optimal one. Predominant group was saturated and monounsaturated acids (occurring in similar amounts), however, polyunsaturated acids content amounted to about 11 % of total fatty acids sum. Energy proportional portion from essential fatty acids, in a whole day's rations, was found to be higher than necessary minimum (3%); on the other hand, it did not cover the recommended standard for subjects advanced in years (4%). Value P:S was noted to correspond with an average european diet. Portion of acids with proaggregative properties was higher than hypercholesteremic acids content.

PL

Przeprowadzona ocena wartości żywieniowej tłuszczu wykazała bogatotłuszczowy charakter badanych racji pokarmowych. Dominującą grupę stanowiły kwasy nasycone i jednonienasycone, które występowały w zbliżonych ilościach. Procent energii z NNKT był wyższy od niezbędnego minimum 3%; jednakże nie pokrywał on zalecanej normy dla tej grupy wiekowej.

15

Wplyw diety o zwiekszonej zawartosci witaminy B6 na wchlanianie aminokwasow w jelicie szczurow narazonych na karbaryl,propoksur i tiuram.Cz.2 Leucyna

59%

Witkowska D. , Sedrowicz L. , Oledzka R.

Bromatologia i Chemia Toksykologiczna

|

1992

|

tom 25

|

nr 1

31-36

EN

Carbaryl, propoksur, and thiuram were administered for 14 days, by a stomach tube, at dosing level corresponding to 5% LD50 , to male Wistar rats four weeks old and fed a diet enriched with vitamin B6 (200 µg/day). Active and passive leucine transport in rat intestine was studies using liquid scintillation method according to Patrick and Papworth, modified by the authors. No disorder of leucine transport was observed in animals exposed to carbaryl and propoksur, and fed a diet enriched with vitamin B6. No disturbances were also noted in subject exposed to thiuram, except that Jm constans was increased by about 170% when compared with the control, and the affinity was decreased (rise of Kt constant by 320%). However, it seems that the diet enriched with vitamin B6, may protect amino acids homeostasis in animals exposed to some xenobiotics.

PL

Badano wchłanianie 14C-leucyny w jelicie szczurów otrzymujących dietę o zwiększonej zawartości witaminy B6 i narażonych na wielokrotne (2 tyg.) działanie karbarylu, propoksuru i tiuramu w dawce 5% LD50.

16

Influence of folic acid, vitamin B2 and B6 supplementation on feed intake, body and organs weight, and liver fatty acids composition in rats subjected to severe protein deprivation

59%

Debski B. , Bertrandt J. , Klos A. , Gralak M.

Polish Journal of Veterinary Sciences

|

2006

|

tom 09

|

nr 3

EN

Growing rats fed for 3 months a low-protein (LP) diet (4.5% of energy from protein), possessed about 29% lower body weight than animals consuming adequate-protein diet (20% energy from protein). The LP diet feeding caused an increase in daily feed intake followed by a decrease in feed conversion efficiency. The enrichment of LP diet with folic acid, vitamin B2 and B() (3 times above the level applied in the control diet) did not have any impact on rats BW and supplementation with these vitamins minimize the effect of LP diet on feed intake. The use of examined vitamins had a tendency to diminish an increase in feed conversion ratio caused by the LP nutrition. This effect was significant when all vitamins were added together. Rats fed the LP diet had higher relative weights of lungs, heart, liver and testis. Vitamins enriching the LP diet were observed to decrease a relative weight of lungs (folic acid, vitamin B6 and vitamin mixture), and liver (vitamin B6 and vitamin mixture). A tendency of increasing relative testis weight was also revealed in rats given the LP diet enriched with vitamins. The lower content of hepatic polyunsaturated fatty acids (FA) and a tendency for monoun- saturated FA content to be higher were found in rats fed the LP diet. The LP diet enrichment with folic acid caused that these changes were more pronounced and statistically significant. Enrichment of LP diet with vitamins tested may cause a partial reverse of changes observed in the hepatic FA composition.

17

Wybrane owoce morza jako skladniki diety o wysokiej wartosci odzywczej

51%

Zdrojewska I. , Lebiedzinska A. , Szefer P.

|

2005

|

tom 56

|

nr 2

131-137

PL

Określono wartość odżywczą oraz wartość energetyczną wybranych skorupiaków morskich (krewetek oraz krabów i homara) dostępnych na polskim rynku żywnościowym. Stwierdzono, że charakteryzują się one wysoką wartością odżywczą oraz dostarczają dużo białka wraz z niewielką ilością energii

EN

Shellfish products available on the Polish market were analyzed for the content of protein fat carbohydrates water, ash energy value and vitamins B. Nutrition value of the analyzed products was determmed by analytical methods applying in food chemistry. Concentrations of niacin and vitamin B6 were determined by microbiological methods.The concentration of the selected shellfishes in 100 g of the analyzed products and percentage of realization on recommended level of nutritive components by analyzed products for adults were determined.

18

Ocena zawartosci wybranych witamin rozpuszczalnych w wodzie w calodziennej racji pokarmowej studentow AMB

51%

Czapska D. , Ostrowska L. , Stefanska E. , Karczewski J.

Bromatologia i Chemia Toksykologiczna

|

2005

|

tom 38

|

nr Supl.

63-65

PL

W całodziennej racji pokarmowej studentów AMB oceniono zawartość witaminy C, B1, B2, B6 i PP. Wyższą podaż badanych witamin odnotowano w całodziennej racji pokarmowej studentek.

EN

The content of vitamins B1 B2, B6, PP and C in the daily diet of the Białystok Medical University students was assessed. A 24-hour dietary history was taken among 86 female and 42 male students aged 19-22 years. The vitamin supply varied according to students'.gender. The students' menus were characterized by high vitamin C content. Higher supply of vitamins B1 B2, B6 and PP was noted in a daily food ration of female students as compared with male subjects.

19

Wybrane produkty zbozowe jako elementy funkcjonalne diety - czestosc spozycia produktow zbozowych wsrod studentow

51%

Lebiedzinska A.

Roczniki Państwowego Zakładu Higieny

|

2007

|

tom 58

|

nr 1

295-300

PL

W produktach zbożowych (mąki, mieszanki wypiekowe, pieczywo) oznaczono zawartość witamin B1 i B6. Mąki pełnoziarniste charakteryzują się najwyższą koncentracją analizowanych witamin. W oparciu o badania ankietowe przeprowadzono ocenę częstości spożycia produktów zbożowych oraz rodzaju spożywanego pieczywa wśród 171 studentów. Stwierdzono, że większość badanych spożywa produkty zbożowe dwukrotnie w całodziennej racji pokarmowej, ponadto preferują pieczywo jasne.

EN

The present study provides information about concentration of vitamins B1 and B6 in grain products as well as frequency of intake cereal products by students. Higher thiamine and vitamin B6 content was detected in the whole wheat flour. The group of 171 pupils was investigated. Frequency of cereal products consumption and choice of kind of bread intake was estimated using self-report questionnaire. The results of the study showed that respondents were more familiar with wheat bread. Most students reported the consumption of cereal products two times per day.

20

Dieta, homocysteina, choroby sercowo-naczyniowe

51%

Klosiewicz-Latoszek L. , Ostrowska A.

Bromatologia i Chemia Toksykologiczna

|

2000

|

tom 33

|

nr 4

381-387