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  1. 7 Roczniki Państwowego Zakładu Higieny
  2. 6 Bromatologia i Chemia Toksykologiczna
  3. 5 Polish Journal of Food and Nutrition Sciences
  4. 2 Acta Biochimica Polonica
  5. 2 Acta Scientiarum Polonorum. Technologia Alimentaria
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  1. 1 2018
  2. 1 2016
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  4. 2 2011
  5. 1 2009
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  1. 5 Lebiedzinska A.
  2. 5 Szefer P.
  3. 5 Szymandera-Buszka K.
  4. 4 Waszkowiak K.
  5. 2 Czaja J.
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1
Content available Ifosfamide-induced encephalopathy in a patient with metastatic fibrosarcoma
100%
Galus Ł.
OncoReview
|
2016
|
tom 6
|
nr 4
A179-183
EN
Ifosfamide is a cytostatic drug commonly used in chemotherapy. One of the common adverse effects resulting from the treatment with ifosfamide is encephalopathy. This paper describes a case study of a 64-year-old patient who suffered from a full-blown encephalopathy as a result of chemotherapy administered during the treatment of fibrosarcoma of the femur. It provides a hypothesis of the mechanism behind toxic effects of ifosfamide on the central nervous system and elaborates on a number of documented ways of preventing aforementioned complications.
2
Content available remote Thiamine prevents X-ray induction of genetic changes in human lymphocytes in vitro.
86%
Konopacka M. , Rogoliński J.
Acta Biochimica Polonica
|
2004
|
tom 51
|
nr 3
839-843
EN
The effects of thiamine (vitamin B1) on the level of spontaneous or radiation-induced genetic changes in human lymphocytes in vitro were studied. Cultured lymphocytes were exposed to increasing concentrations of thiamine (0-500 μg/ml) and irradiated with X-rays. The DNA damage was estimated as the frequency of micronuclei and apoptotic or necrotic morphological changes in fixed cells. The results show that thiamine alone did not induce genetic changes. A significant decrease in the fraction of apoptotic and necrotic cells was observed in lymphocytes irradiated in the presence of vitamin B1 at concentrations between 1-100 μg/ml compared to those irradiated in the absence of thiamine. Vitamin B1 at 1 and 10 μg/ml decreased also the extent of radiation-induced formation of micronuclei. Vitamin B1 had no effect on radiation-induced cytotoxicity as measured by nuclear division index. The results indicate that vitamin B1 protects human cells from radiation-induced genetic changes.
3
Production of B-group vitamins by some soil borne fungi pathogenic to groundnut (Arachis hypogea L.)
86%
Dahm H. , Reddy M. N. , Strzelczyk E.
Bulletin of the Polish Academy of Sciences. Biological Sciences
|
1989
|
tom 37
|
nr 1-3
4
Determination of thiamine in premixture and compound feed by liquid chromatography method
86%
Rubaj J. , Korol W. , Bielecka G. , Kwiatek K.
Bulletin of the Veterinary Institute in Puławy
|
2008
|
tom 52
|
nr 3
EN
The analytical procedure of thiamine quantification in premixtures and compound feedingstuffs by HPLC method is presented. Thiamine was extracted from feed samples with 0.1M hydrochloric acid at 100°C for 30 min. In the case of compound feedingstuffs, 10% Taka-diastase solution was added to the samples, and then the samples were incubated at 37°C for 17 h. Afterwards, thiamine was oxidised to thiochrom, using 1% alkaline potassium ferricyanide (III). The filtrated solution was analysed by HPLC with isocratic flow of eluent chloroform-methanol 90:10 (v/v). The measurement was done by a fluorescence detector. This method has been applied for the quantification of the total content of thiamine in compound feedingstuffs, as well as added thiamine in the form of hydrochloride or nitrate salt. The limit of the quantification of this method was determined on the level of 1 mg/kg. The coefficient variation of thiamine quantification results in premixţures samples was 3.7%, and in compound feedingstuffs was 5.56%. The Horrat value for premixture samples reached a value of 0.60, whereas in the case of compound feedingstuffs it was 0.63, thus confirming acceptable precision of the procedure. The recovery rate for thiamine added in the form of hydrochloride was 102.3% in premixes and 98.9% in compound feedingstuffs. The recovery rate for thiamine added in the form of nitrate salt to compound feedingstuffs was similar and reached a value equal to 98.7%.
5
Content available Foliar application of thiamin stimulates the growth, yield and biochemical compounds production of coriander and fenugreek
72%
Aminifard M. H. , Jorkesh A. , Fallahi H.-R. , Alipoor K.
Journal of Horticultural Research
|
2018
|
tom 26
|
nr 1
6
The genes and enzymes involved in the biosynthesis of thiamin and thiamin diphosphate in yeasts
72%
Kowalska E. , Kozik A.
|
|
tom 13
|
nr 2
271-282
EN
Thiamin (vitamin B1) is an essential molecule for all living organisms. Its major biologically active derivative is thiamin diphosphate, which serves as a cofactor for several enzymes involved in carbohydrate and amino acid metabolism. Important new functions for thiamin and its phosphate esters have recently been suggested, e.g. in gene expression regulation by influencing mRNA structure, in DNA repair after UV illumination, and in the protection of some organelles against reactive oxygen species. Unlike higher animals, which rely on nutritional thiamin intake, yeasts can synthesize thiamin de novo. The biosynthesis pathways include the separate synthesis of two precursors, 4-amino-5-hydroxymethyl-2-methylpyrimidine diphosphate and 5-(2-hydroxyethyl)-4-methylthiazole phosphate, which are then condensed into thiamin monophosphate. Additionally, yeasts evolved salvage mechanisms to utilize thiamin and its dephosphorylated late precursors, 4-amino-5-hydroxymethyl-2-methylpyrimidine and 5-(2-hydroxyethyl)-4-methylthiazole, from the environment. The current state of knowledge on the discrete steps of thiamin biosynthesis in yeasts is far from satisfactory; many intermediates are postulated only by analogy to the much better understood biosynthesis process in bacteria. On the other hand, the genetic mechanisms regulating thiamin biosynthesis in yeasts are currently under extensive exploration. Only recently, the structures of some of the yeast enzymes involved in thiamin biosynthesis, such as thiamin diphosphokinase and thiazole synthase, were determined at the atomic resolution, and mechanistic proposals for the catalysis of particular biosynthetic steps started to emerge.
7
Vitamins B1, B2, B6 in raw and processed buckwheat sprouts
72%
Ornatowska A. , Penas E. , Frias J. , Vidal-Valverde C. , Piskula M. K.
Polish Journal of Food and Nutrition Sciences
|
2011
|
tom 61
|
nr Suppl.1
8
Content available remote Flow through sensor for the chemiluminescence determination of thiamine
72%
Song Z. , Hou S.
Chemia Analityczna
|
2002
|
tom Vol. 47, No. 5
747-757
EN
A novel chemiluminescence (CL) sensor for thiamine combined flow-injection (FI) technology is presented in this paper. The analytical reagents, luminol and ferricyanide, were both immobilized on an anion exchange column. The CL signal produced by the reaction between luminol and ferricyanide, which were eluted from the column with the sodium phosphate injection, was decreased in the presence of thiamine. The decreased CL intensity was linear for thiamine concentration in the range from 0.2 to 4.0 nmol mL(-1); and the limit of detection was 66 pmol mL(-1) (3sigma). The whole process, including sampling and washing, could be completed in 2 min with a relative standard deviation of less than 3.0%. The sensor could be reused more than 400 times and has been applied for the determination of thiamine in pharmaceutical preparations and human urine samples.
PL
Opracowano nowy sensor do oznaczania tiaminy w przepływie oparty napomiarze chemiluminescencji (CL). Reagenty: luminol, heksacjanożelazian(III) potasu sąpoczątkowo związane na kolumnie anionowymiennej. Po wymyciu reagentów z kolumny wstrzykiwanym fosforanem sodu, w wyniku reakcji pomiędzy luminolem i heksacjanożelazianem powstaje sygnał CL, który w obecności tiaminy jest osłabiony. Zmiana sygnału CL jest proporcjonalna do stężenia tiaminy w zakresie od 0.02 do 4 nmol mL(-1). Granica wykrywalności, liczona jako 3-krotne odchylenie standardowe, wynosi 66 pmol mL(-1). Cały proces analityczny można wykonać w 2 min, a sensor może być użyty przynajmniej 400 razy. Opracowany sensor został zastosowany do oznaczania tiaminy w preparatach farmaceutycznych i w moczu.
9
Occurrence of some B-group vitamins in the root and seed exudates of groundnut (Arachis hypogea L.)
72%
Wlodarski K. H. , Marciniak M. M.
Bulletin of the Polish Academy of Sciences. Biological Sciences
|
1989
|
tom 37
|
nr 1-3
10
Impact of B-group vitamins on growth of Azospirillum
72%
Rozycki H. , Strzelczyk E. , Li C. Y.
Acta Microbiologica Polonica
|
1996
|
tom 45
|
nr 2
11
Comparative evaluation of nutritive and sensory value of selected raw materials and dishes after thermal processing in a convection oven and with conventional methods
72%
Waszkowiak K. , Szymandera-Buszka K. , Janitz W. , Gorecka D.
Electronic Journal of Polish Agricultural Universities. Series Food Science and Technology
|
1999
|
tom 02
|
nr 2
EN
In the research the effect of thermal processing in a convection oven on dishes quality was evaluated. The quantitative and qualitative changes of some nutritive values and sensory indices were estimated in comparison with conventional methods of thermal processing. In the study raw materials and dishes of vegetable (sauerkraut and potatoes) and animal origin (cooked and roasted meat, cooked and fried minced meat balls) were investigated. The content of ascorbic acid and neutral detergent fiber (NDF) were used as the nutrition value indices of investigated vegetable dishes. Thiamine and collagen changes in meat dishes and retention of iodine in the products (meat balls) with addition of iodized salt were analyzed. All prepared dishes were sensory evaluated with the triangle test.
12
Thiamine prevents X-ray induction of genetic changes in human lymphocytes in vitro
72%
Konopacka M. , Rogolinski J.
Acta Biochimica Polonica
|
2004
|
tom 51
|
nr 3
EN
The effects of thiamine (vitamin B1) on the level of spontaneous or radia­tion-induced genetic changes in human lymphocytes in vitro were studied. Cul­tured lymphocytes were exposed to increasing concentrations of thiamine (0-500 Ug/ml) and irradiated with X-rays. The DNA damage was estimated as the frequency of micronuclei and apoptotic or necrotic morphological changes in fixed cells. The results show that thiamine alone did not induce genetic changes. A significant decrease in the fraction of apoptotic and necrotic cells was observed in lymphocytes irradiated in the presence of vitamin B1 at concentrations between 1-100 ug/ml compared to those irradiated in the absence of thiamine. Vitamin B1 at 1 and 10 Ug/ml decreased also the extent of radiation-induced formation of micronuclei. Vita­min B1 had no effect on radiation-induced cytotoxicity as measured by nuclear divi­sion index. The results indicate that vitamin B1 protects human cells from radia­tion-induced genetic changes.
13
The influence of dietary pectins and cellulose on thiamine utilisation in vivo
72%
Drywien M. , Mierzejewska M.
Polish Journal of Food and Nutrition Sciences
|
2002
|
tom 11/52
|
nr 4
EN
In the study of the concentration of thiamine in the plasma, liver, urine and faeces as indices of its utilisation we found that cellulose enhances the bioavailability of this vitamin in vivo; however, pectin has an opposite effect, that is, it lowers its bioavailability.
PL
Celem badań było wykazanie czy i w jakim stopniu wybrane frakcje błonnika pokarmowego (celuloza i pektyna) wpływają na wykorzystanie tiaminy wewnątrzustrojowej (produkowanej przez mikroflorę jelitową) w organizmie szczura. Jako mierniki wykorzystania tiaminy przyjęto jej ilości oznaczone w osoczu krwi, wątrobie, moczu oraz kale. Przeprowadzono dwutygodniowe doświadczenie na szczurach-samcach szczepu Wistar, podczas którego podawano zwierzętom diety doświadczalne zawierające 5% i/lub 10% celulozy i/lub pektyny oraz dietę bezbłonnikową jako kontrolną. Szczurom nie podawano tiaminy. Podczas doświadczenia każdego dnia kontrolowano masę ciała zwierząt i ilość spożytej diety oraz zbierano mocz i kał. Po zakończeniu doświadczenia zwierzęta usypiano, pobierano krew i wątrobę. Zawartość tiaminy w materiale biologicznym oznaczano zmodyfikowaną fluorymetryczną metodą Leveille'a. W efekcie przeprowadzonych badań stwierdzono, że: (a) w grupie zwierząt otrzymujących diety z udziałem 10% celulozy zauważalna była tendencja wzrostowa zawartości tiaminy w wątrobie i osoczu przy istotnie niewielkim jej wydalaniu z kałem i moczem; (b) przy podawaniu diety zawierającej 10% pektyny wykazano znaczący spadek koncentracji tiaminy w osoczu krwi oraz moczu, zmniejszenie jej ilości w wątrobie natomiast duże ilości tiaminy w kale. Niniejsze badania wykazały, że w warunkach braku tiaminy pokarmowej celuloza może zwiększać wykorzystanie tiaminy wewnątrzustrojowej (produkowanej przez mikroflorę jelitową) a pektyna zmniejszać.
14
Nutritional factors and thiamine bioavailability - a review
72%
Drywien M. , Gronowska-Senger A.
Polish Journal of Food and Nutrition Sciences
|
2000
|
tom 09/50
|
nr 2
EN
There is relatively little information concerning the bioavailability of thiamine from food products; nevertheless available data on thiamine show that this vitamin is a significant factor that plays an important role in their nutritional status. The bioavailability of thiamine depends on several factors of which food and diet composition appears to play a paramount importance.
15
Content available Oznaczanie tiaminy metodą tiochromową w małych ilosciach krwi i płynu mózgowo-rdzeniowego
58%
Luczakowa M.
Roczniki Państwowego Zakładu Higieny
|
1957
|
tom 08
|
nr 2
16
The effects of cadmium on the absorption of thiamine, calcium, magnesium and phosphates and on the activity of lactate dehydrogenase (LDH) in the intestines of rats
58%
Dolezych S. , Dolezych B. , Szmatloch A. , Mekail A. , Jethon Z. , Bytomska S.
Acta Biologica Silesiana
|
1990
|
tom 15
17
Wplyw pantotenianu wapnia z tiamina oraz wybranych zwiazkow mineralnych na przebieg fermentacji alkoholowej zytnich zacierow gorzelniczych [2]
58%
Kotarska K. , Czuprynski B. , Klosowski G. , Wolska M.
Przemysł Fermentacyjny i Owocowo-Warzywny
|
2005
|
tom 49
|
nr 05
34-37
EN
The aim of this research was a study of the influence of calcium pantothenate with thiamine and selected mineral compounds on alcoholic fermentation course of rye mash with the density of 19,5°Blg and 25,1°Blg and the quality of raw spirit obtained. The research was conducted with a sweet rye mash made according to Henze technology. Basing on the research it was stated that the additive of a few mineral compounds as ammonium sulfate, potasium biphosphate, magnesium sulfate to rye mash of 19,5°Blg increase the productivity of ethanol obtaining process from starch. Resides there is an improvement of all biotechnological indexes of fermentation and the level reduction of higher alcohols and esters content in raw spirits. However an additive of calcium pantothenate with thiamine to the mash of the same density causes the quality improvement of the obtained raw spirit by reduction of the formed aldehydes and fusel oils without essential influence on fermentation process. At higher density of rye mash up to 25,1°Blg the best biotechnological indexes of fermentation process and the highest reduction of the formed impurities of raw spirit were reached by tests with additive of calcium pantothenate with thiamine.
PL
Celem pracy było zbadanie wpływu dodatku wybranych związków mineralnych oraz pantotenianu wapnia z tiaminą na przebieg procesu fermentacji alkoholowej zacieru żytniego o gęstości 19,5° Вlg i 25,1° Blg oraz jakość uzyskanego spirytusu surowego. Badania prowadzono na słodkim zacierze żytnim sporządzonym według technologii Henze' go. Na podstawie przeprowadzonych badań stwierdzono, że dodatek kilku związków mineralnych, tj. siarczanu amonu, wodorofosforanu potasu, siarczanu magnezu, do zacieru żytniego o gęstości 19,5°Blg, powoduje wzrost wydajności etanolu ze skrobi i poprawę wszystkich wskaźników biotechnologicznych fermentacji przy jednoczesnym obniżeniu poziomu alkoholi wyższych i estrów w spirytusach surowych. Natomiast dodatek pantotenianu wapnia wraz z tiaminą do zacieru o tej gęstości powoduje poprawę jakości uzyskiwanego spirytusu surowego, poprzez ograniczenie ilości tworzących się aldehydów i fuzli, nie wywierając znaczącego wpływu na proces fermentacji. Przy zwiększonej gęstości żytniego zacieru do wartości 25,1°Blg, najlepsze wskaźniki biotechnologiczne procesu fermentacji oraz najwyższe ograniczenie powstawania zanieczyszczeń spirytusu surowego odnotowano w próbach, w których zastosowano pantotenian wapnia wraz z tiaminą.
18
Content available Badania nad wpływem procesów technologicznych na zawartość tiaminy i ryboflawiny w kiełbasie serdelowej z uwzględnieniem ochronnej roli osłonki naturalnej
58%
Stobnicka H.
Roczniki Państwowego Zakładu Higieny
|
1957
|
tom 08
|
nr 2
19
Evaluation of vitamins B1 and B2, soluble proteins and phytic acid in buckwheat enhanced wheat bread
58%
Frias J. , Penas E. , Szawara-Nowak D. , Zielinski H. , Vidal-Valverde
Polish Journal of Food and Nutrition Sciences
|
2011
|
tom 61
|
nr Suppl.1
20
Content available Wartość odżywcza konserw z zielonego groszku. Część II. Zawartość niektórych witamin
58%
Secomska B. , Dietl B. , Ksiezny S.
Roczniki Państwowego Zakładu Higieny
|
1956
|
tom 07
|
nr 1
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