Wyniki wyszukiwania - Biblioteka Nauki

1

The citric acid-modified, enzyme-resistant dextrin from potato starch as a potential prebiotic

100%

Śliżewska K.

Acta Biochimica Polonica

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2013

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tom 60

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nr 4

671-675

EN

In the present study, enzyme-resistant dextrin, prepared by heating of potato starch in the presence of hydrochloric (0.1% dsb) and citric (0.1% dsb) acid at 130ºC for 3 h (CA-dextrin), was tested as a source of carbon for probiotic lactobacilli and bifidobacteria cultured with intestinal bacteria isolated from feces of three healthy 70-year old volunteers. The dynamics of growth of bacterial monocultures in broth containing citric acid (CA)-modified dextrin were estimated. It was also investigated whether lactobacilli and bifidobacteria cultured with intestinal bacteria in the presence of resistant dextrin would be able to dominate the intestinal isolates. Prebiotic fermentation of resistant dextrin was analyzed using prebiotic index (PI). In co-cultures of intestinal and probiotic bacteria, the environment was found to be dominated by the probiotic strains of Bifidobacterium and Lactobacillus, which is a beneficial effect.

2

Prebiotics and bioactive natural substances induce changes of composition and metabolic activities of the colonic microflora in cancerous rats

88%

Hijová E. , Bomba A. , Bertková I. , Strojný L. , Szabadosová V. , Šoltésová A.

Acta Biochimica Polonica

|

2012

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tom 59

|

nr 2

271-274

EN

Prebiotics are defined as selectively fermented food ingredients that induce specific changes in the composition and/or activity in the gastrointestinal microbiota beneficial to the host well-being and health. The aim of the presented experiment was to investigate the effect of a prebiotic applied alone or in combination with Hyppocastani extractum siccum, and Lini oleum virginale in rats with dimethylhydrazine induced colon cancer. Wistar albino rats were fed high fat diet supplemented with the prebiotic alone or in combination with Horse chestnut and flaxseed oil. The activity of faecal glycolytic enzymes, lipid parameters, bile acids, short chain fatty acids and counts of coliforms and lactobacilli were determined. Treatment with the prebiotic alone and in combination with selected substances significantly decreased the activity of glycolytic bacterial enzyme β-glucuronidase (P<0.001) and increased activities of β-galactosidase and β-glucosidase. Bile acids concentration was significantly decreased (P<0.01) except for the combination of the prebiotic with Horse chestnut. The prebiotic alone decreased the lipid parameters (P<0.001) and enhanced production of short chain fatty acids. Application of prebiotic and bioactive natural substances significantly reduced number of coliforms (P<0.05). Prebiotic alone significantly increased the count of lactobacilli (P<0.05). These results show that prebiotics have a protective effect and may be the useful for colon cancer prevention and treatment.

3

Discrete dynamic system oriented on the formation of prebiotic dipeptides from Rode's experiment

88%

Polanco C. , Samaniego J. L. , Buhse T. , Castanon Gonzales J. A.

Acta Biochimica Polonica

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2014

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tom 61

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nr 4

4

Type IV resistant starch increases cecum short chain fatty acids level in rats

88%

Le Thanh-Blicharz J. , Anioła J. , Kowalczewski P. , Przygoński K. , Zaborowska Z. , Lewandowicz G.

Acta Biochimica Polonica

|

2014

|

tom 61

|

nr 1

109-114

EN

Resistant starches are type of dietary fibers. However, their physiological effects depend on the way they resist digestion in the gastrointestinal tract. The objective of this study was to examine the hypothesis that new type of RS4 preparations, of in vitro digestibility of about 50%, obtained by cross-linking and acetylation, acts as a prebiotic by increasing short chain fatty acids content in cecum digesta. The rats were fed with diet containing pregelatinized, cross-linked and acetylated starches as a main carbohydrate source. Pregelatinized, but not chemically modified, potato starch was used in the composition of the control diet. After two weeks of experiment the increase of short chain fatty acids contents in ceceum digesta was observed. The intake of starch A, cross-linked only with adipic acid, resulted in increase of about 40% of short chain fatty acids content, whereas starch PA cross-linked with sodium trimetaphosphate and adipic acid of about 50%. The utmost twofold increase was observed in the case of the production of propionic acid. In contrast, the content of butyric acid increased (12%) only as an effect of consumption of starch PA and even decreased (about 30%) in case of starch A. Both RS4 starches caused an increase of the production of acetic acid by more than 40%. No changes in serum biochemistry, liver cholesterol and organ weights of rats were stated.

5

Effect of inulin and oligofructose on caecal pH during various thiamine doses administration in rats

75%

Drywien M.

Polish Journal of Food and Nutrition Sciences

|

2007

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tom 57

|

nr 2

253-256

EN

A 15-day experiment was performed on male Wistar rats allocated into three blocks diversified by a daily thiamine dose: 0, 20, 40 μg/day/rat. In each block the rats were divided into five groups depending on the type of diet: control group (FF) – fructan-free diet; experimental groups (I-5, I-10, OF-5, OF-10) – diets containing: 5%, 10% of inulin, as well as 5%, 10% of oligofructose respectively. Thiamine-free experimental diets were prepared according to AIN-93M recommendations, where inulin and oligofructose were added instead of wheat starch. The thiamine was administered per os as a water solution. Compared to the initial value, caecal pH decreased in all groups of rats. The daily thiamine dose as well as the kind of fructan influenced caecal pH. There could be observed the synergistic action of inulin and thiamine in decreasing pH. Inulin and oligofructose, due to prebiotic properties, can cause fluctuations in the caecum pH but the direction of changes is closely dependent on the presence of dietary thiamine. The most suitable pH values for endogenous thiamine uptake are reported during dietary deficit of this vitamin, independently on the type and dose of fructan.

PL

Przeprowadzono 15-to dniowe doświadczenie z wykorzystaniem szczurów (samców) szczepu Wistar. Obejmowało ono trzy bloki zróżnicowane pod względem dawki tiaminy: 0, 20, 40 μg/dzień/szczura. W każdym z nich zwierzęta podzielono na grupy zależnie od rodzaju podawanej diety: grupa kontrolna (FF) – dieta bez prebiotyku; grupy badane (I-5, I-10, OF-5, OF-10) – diety zawierające odpowiednio: 5%, 10% inuliny lub 5%, 10% oligofruktozy. Diety doświadczalne, pozbawione tiaminy, przygotowano zgodnie z zaleceniami AIN-93M, w których część skrobi pszennej zastąpiono odpowiednimi dodatkami w/w prebiotyków. Tiaminę podawano per os w postaci roztworu wodnego. Na podstawie uzyskanych wyników stwierdzono, że pH treści jelita ślepego obniżyło się we wszystkich badanych grupach w porównaniu do grupy wyjściowej, która otrzymywała paszę bytową granulowaną (rys. 1 i 2). Zarówno dawka jak i rodzaj prebiotyku wpłynęły na pH treści jelita ślepego szczura. Zaobserwowano również synergistyczne działanie inuliny i tiaminy w obniżaniu pH (rys. 3). Inulina i oligofruktoza, dzięki prebiotycznym właściwościom, mogą zmieniać pH treści jelita ślepego szczurów ale kierunek zmian jest ściśle uzależniony od obecności tiaminy pokarmowej. Najodpowiedniejsze wartości pH dla wchłaniania tiaminy endogennej stwierdzono w warunkach deficytu tej witaminy w diecie, niezależnie od rodzaju i ilości fruktanu.

6

A pilot study of tissue factor-tissue factor pathway inhibitor axis and other selected coagulation parameters in broiler chickens administered in ovo with selected prebiotics

75%

Buzala M. , Ponczek M. B. , Slomka A. , Roslewska A. , Janicki B. , Zekanowska E. , Bednarczyk M.

Folia Biologica

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2016

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tom 64

|

nr 4

7

The evaluation of usefulness of potentially probiotic Lactobacillus strains as components of industrial starter cultures

75%

Modzelewska-Kapitula M. , Klebukowska L. , Kornacki K. , Lukaszuk W.

Polish Journal of Natural Sciences

|

2009

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tom 24

|

nr 4

254-262

EN

The aim of the study was to investigate the possible use of nine Lactobacillus strains, previously isolated from infants faeces, as components of industrial starter cultures for yoghurt, soft white cheese and hard cheese production. There were no strong antagonistic interactions between isolates and commercial probiotics and yoghurt strains. None of isolates was able to grow at 3℃, seven grew at 7℃, all of them at 12℃ and 37℃ and only three at 45℃. In the culture media containing 10.4% NaCl at pH 6.5 growth of four isolates was detected at 12℃, whereas six strains grew at 37℃. Tested isolates did not hydrolyze casein and arginine and did not produce H₂S. Inulins (HD, IQ, TEX, HPX) and maltodextrins (low and medium dextrose equivalent) added to the culture media stimulated the growth of isolates. The properties of all isolates enable their application in soft white and hard cheeses and strains 4a, 4b and 14 in yoghurts.

PL

Celem pracy było określenie możliwości zastosowania dziewięciu szczepów z rodzaju Lactobacillus, wyizolowanych z kału niemowląt, jako komponentów szczepionek przemysłowych do produkcji jogurtów, serów twarogowych i dojrzewających. Nie odnotowano silnych antagonistycznych interakcji między izolatami, komercyjnymi szczepami probiotycznymi i jogurtowymi. Żaden spośród badanych izolatów nie wykazał zdolności do wzrostu w temperaturze 3℃, siedem było zdolnych do wzrostu w 7℃, wszystkie rosły w 12℃ i 37℃, a tylko trzy – w 45℃. W podłożach zawierających 10.4% NaCl i o pH 6,5 odnotowano wzrost czterech szczepów w temperaturze 12℃ i sześciu w 37℃. Badane izolaty nie wykazały zdolności do rozkładu kazeiny i argininy oraz produkcji H₂S. Inuliny (HD, IQ, TEX, HPX) i maltodekstryny (nisko- i średnioscukrzona) dodane do podłoży stymulowały wzrost izolatów. Właściwości wszystkich izolatów umożliwiają ich zastosowanie w serach twarogowych i dojrzewających, a szczepów 4a, 4b i 14 w jogurtach.

8

Probiotics and prebiotics

75%

Szkaradkiewicz A. K. , Karpinski T. M.

Journal of Biology and Earth Sciences

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2013

|

tom 03

|

nr 1

9

Growth and survival of prebiotic lactic acid bacteria in the presence of heterocyclic aromatic amines

75%

Nowak A.

Żywność Nauka Technologia Jakość

|

2014

|

tom 21

|

nr 3

EN

Heterocyclic aromatic amines (HCAs) ingested with heat-processed meat can contribute to colon cancer development. Those compounds interact with human intestinal microbiota. Under the research study, the effect was analyzed of IQ, MeIQx, or PhIP amines (each of them at 5 and 25 μg/ml concentration rates) on the growth (24 h cultivation in MRS broth) and survival (incubation for max. 120 h in a phosphate buffer) of four probiotic strains of Lactobacillus. It was found that no concentration level of the HCAs analyzed impacted the growth of bacteria. A higher concentration level of IQ (25 μg/ml) decreased the survival of Lb. casei 0900 after a 24 h period of incubation. MeIQx and PhIP also decreased the survival of Lb. paracasei 0919 after a 24 h period of incubation. Totally, the count of living cells decreased from 109 cfu/ml to 108 cfu/ml. Three strains were absolutely resistant to PhIP during a 120 h period of incubation. The results obtained prove that the probiotic bacteria studied maintain their high viability in the presence of the amines tested and, probably, they can bind together with them in human colon and, then, the aggregated particles are removed from the human body.

PL

Heterocykliczne aminy aromatyczne (HCA) spożywane wraz z termicznie przetworzonym mięsem mogą przyczyniać się do rozwoju raka jelita grubego. W pracy badano wpływ amin IQ, MeIQx oraz PhIP (każda w stężeniu 5 i 25 μg/ml) na wzrost (24-godzinna hodowla w pożywce MRS) i przeżywalność (do 120 h inkubacji w buforze fosforanowym) czterech szczepów probiotycznych z rodzaju Lactobacillus. Zaobserwowano, że żadne z badanych stężeń HCA nie wpływało na wzrost bakterii. Wyższe stężenie IQ (25 μg/ml) obniżało żywotność szczepu Lb. casei 0900 od 24 h inkubacji. Aminy MeIQx i PhIP obniżały żywotność Lb. paracasei 0919 również od 24 h inkubacji. Generalnie liczba żywych komórek obniżyła się z 109 jtk/ml do 108 jtk/ml. Trzy szczepy były całkowicie oporne na obecność PhIP podczas 120 h inkubacji. Uzyskane rezultaty wskazują, że badane szczepy probiotyczne zachowują wysoką żywotność w obecności testowanych amin i prawdopodobnie mogą wiązać się z nimi w jelicie grubym, po czym te zagregowane cząstki usuwane są z organizmu.

10

A toy model of prebiotic peptide evolution: the possible role of relative amino acid abundances

75%

Polanco C. , Buhse T. , Samaniego J. L. , Castanon-Gonzalez J. A.

Acta Biochimica Polonica

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2013

|

tom 60

|

nr 2

EN

This paper presents a mathematical-computational toy model based on the assumed dynamic principles of prebiotic peptide evolution. Starting from a pool of amino acid monomers, the model describes in a generalized manner the generation of peptides and their sequential information. The model integrates the intrinsic and dynamic key elements of the initiation of biopolymerization, such as the relative amino acid abundances and polarities, as well as the oligomer reversibility, i.e. fragmentation and recombination, and peptide self-replication. Our modeling results suggest that the relative amino acid abundances, as indicated by Miller-Urey type electric discharge experiments, played a principal role in the early sequential information of peptide profiles. Moreover, the computed profiles display an astonishing similarity to peptide profiles observed in so-called biological common ancestors found in the following three microorganisms; E. coli, M. jannaschii, and S. cereviasiae. The prebiotic peptide fingerprint was obtained by the so-called polarity index method that was earlier reported as a tool for the identification of cationic amphipathic antibacterial short peptides.

11

Effects of prebiotics and synbiotics delivered in ovo on broiler small intestine histomorphology during the first days after hatching

75%

Bogucka J. , Dankowiakowska A. , Elminowska-Wenda G. , Sobolewska A. , Szczerba A. , Bednarczyk M.

Folia Biologica

|

2016

|

tom 64

|

nr 3

12

Chitosan derivatives, prebiotics?

75%

Mateos-Aparicio I. , Mengibar M. , Iglesias S. , Kolida S. , Rastall R. , Heras A.

Polish Journal of Food and Nutrition Sciences

|

2011

|

tom 61

|

nr Suppl.1

13

Probiotics, prebiotics and antioxidants as functional foods

75%

Grajek W. , Olejnik A. , Sip A.

Acta Biochimica Polonica

|

2005

|

tom 52

|

nr 3

EN

The term "functional foods" comprises some bacterial strains and products of plant and animal origin containing physiologically active compounds beneficial for human health and reducing the risk of chronic diseases. Among the best known functional compounds probiotics, prebiotics and natural antioxidants should be given as examples. These substances can be obtained by biotechnological methods and by extraction from plant or animal tissues.

14

Prebiotic properties of pea alpha-galactoside preparation applied to chicken per os

75%

Lisowski M. , Lewandowska M. , Bednarczyk M. , Gulewicz P. , Gulewicz K.

Bulletin of the Polish Academy of Sciences. Biological Sciences

|

2003

|

tom 51

|

nr 4

15

Physiological effect of low digestible oligosaccharides in diets for animals and humans

75%

Zdunczyk Z.

Polish Journal of Food and Nutrition Sciences

|

2004

|

tom 13/54

|

nr Spec.Issue 1

16

Personalized vaccination? II. The role of natural microbiota in a vaccine-induced immunity

63%

Dlugonska H. , Grzybowski M.

Wiadomości Parazytologiczne

|

2011

|

tom 57

|

nr 2

EN

Inter-individual variation in immune response to widely used prophylactic vaccines against infectious diseases is strongly influenced by sex, MHC (Major Histocompatibility Complex), age and current hormones status of vaccinated individuals. Numerous findings showed that microorganisms residing at different sites of human or animal body (natural microbiota), especially in the gastrointestinal tract, appear to contribute to nearly every element of the host’s physiology. Recently, the microbiota is also supposed to be an underappreciated yet, but very important factor responsible for diverse vaccine efficacy observed in humans from developing vs. developed countries. In the article, selected aspects of the microbiota – host relation are presented: importance of the gut microbiota in the development of both the intestinal mucosal and systemic immune responses, bacteria of a predominant role for the immunity (e.g., SFB, Segmented Filamentous Bacteria), and several clinical observations on the varied immunogenicity of the same vaccines in different human populations. In the light of our current knowledge, manipulation of the microbiota by probiotics and/or prebiotics is becoming a realistic therapeutic and prophylactic strategy for many infectious, inflammatory and even neoplastic diseases within the gut but it may be also used for improving vaccine efficacy.

17

Influence of prebiotics and butyric acid on the composition of intestinal microflora of broiler chickens

63%

Gajewska J. , Riedel J. , Bucka J. , Zabik A. , Michalczuk M.

Annals of Warsaw University of Life Sciences - SGGW. Animal Science

|

2012

|

tom 51

EN

The main problem addressed in this study was to determine the influence of prebiotic preparations DSM Nutritional Products (Biofit Booster and Alphamune) containing hemicelluloses in the form of extracts from the cell wall of Saccharomyces cerevisiae yeast and butyric acid (preparation Adimix) on the quantitative and qualitative status of intestinal microflora of broiler chickens. The study demonstrated a highly beneficial effect of the Alphamune food additive, containing glucans and mannans as an extract from Saccharomyces cerevisiae yeasts cell wall (index coli/lacto: 0.21).

PL

Wpływ prebiotyków i kwasu masłowego na stan mikroflory jelitowej brojlerów kurzych. Celem pracy było zbadanie wpływu wybranych preparatów prebiotycznych firmy DSM Nutritional Products (Biofit Booster i Alphamu-ne), zawierających hemicelulozy w postaci wyciągów ze ściany komórkowej drożdży Saccharo-myces cerevisiae oraz preparatu zakwaszającego Adimix (kwas masłowy) na ilościowy i jakościowy skład mikroflory jelitowej brojlerów kurzych. Stwierdzono bardzo korzystne działanie prebio-tycznego dodatku paszowego Alphamune zawierającego glukany i mannany w postaci wyciągu ze ścian komórkowych drożdży Saccharomyces cerevisiae (wskaźnik coli/lacto - 0,21).

18

Physiological influence of a probiotic, prebiotic and enzymatic preparation or a combination of these supplements in diets for growing rats

63%

Semaskaite A. , Juskiewicz J. , Zdunczyk Z. , Gruzauskas R.

Polish Journal of Natural Sciences. Supplement

|

2006

|

tom 03

569-574

19

Comparison of the effects of Chinese herbs, probiotics and prebiotics with those of antibiotics in diets on the performance of meat ducks

63%

Wang J. , Zhou H.

Journal of Animal and Feed Sciences

|

2007

|

tom 16

|

nr 1

96-103

20

Preparation, characterization and optimization of cross-linked fructosyltransferase aggregates for the production of prebiotic fructooligosaccharides

63%

Ademakinwa A. N. , Ayinla Z. A. , Omitogun O. G. , Agboola F. K.

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

|

2018

|

tom 99

|

nr 4