Wyniki wyszukiwania - Biblioteka Nauki

1

Zależności pomiędzy tkanką kostną a tkanką tłuszczową

100%

Bienko M. , Lis A. , Wolski D. , Radzki R. P.

Medycyna Weterynaryjna

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2016

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tom 72

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nr 04

EN

Despite its apparent stability, bone tissue is an extremely dynamic structure, responding to diverse and multidirectional interactions by changes in its metabolism. Adipose tissue is no longer seen as a mere store of energy reserves for the organism, but is also recognized as an important endocrine organ. There are several relationships between the two types of tissue, which result from the influence of fat tissue on bone tissue. This influence is expressed through a direct influence of adipokines on bone metabolism and through indirect effects and regulatory impact of adipose tissue on other hormones associated with the metabolism of bone tissue. Osteotropic effects of adipose tissue also result from mechanical load on the skeleton. The aim of this paper was to present the mechanisms of mutual interactions between adipose tissue and bone tissue. The authors also tried to answer the question of whether obesity promotes the development of osteoporosis or whether it is a protective factor for the skeletal system.

2

Wplyw estradiolu i tamoksifenu na wlasciwosci fizyczne kosci udowej i ramiennej kurczat brojlerow

100%

Radzki R. P. , Biensko M. , Puzio I. , Studzinski T.

Medycyna Weterynaryjna

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2003

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tom 59

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nr 12

1090-1094

3

Osteochondroza i dyschondroplazja piszczelowa u kurczat, swin i zrebiat

100%

Sliwa E. , Radzki R. P. , Puzio I.

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nr 03

156-158

4

Wplyw ranelinianiu strontu na mineralizacje i wytrzymalosc mechaniczna kosci udowej orchidektomizowanych szczurow

100%

Radzki R. P. , Bienko M. , Filip R.

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tom 63

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nr 12

1630-1634

EN

The purpose of the study was to determine the effect of Strontium Ranelate (RS) on the mineral density and mechanical properties of the femur in male Wistar rats during experimental osteopenia induced by bilateral gonadectomy. After adaptation, the rats were randomly divided and subjected to sham-operations (SHO) (n = 10) and bilateral orchidectomy (ORX) (n = 20). ORX rats were subsequently divided into the control group (ORX/K) and experimental group treated with RS (ORX/RS), administered by gavage, at a dose of 900 mg/kg b.w. The experiment lasted 60 days and then the animals were killed, blood collected, and femora isolated. Femora were analyzed using peripheral quantitative computed tomography (pQCT) to determine volumetric bone mineral density of the cortical part of the shaft of the column (Ct.vBMD), endoosteal and periosteal circumferences, cortical thickness (Ct.Th) and Strength Strain Index (SSI). Measurements were performed on 50% of bone length. The bones were tested using the three-point bending test to estimate ultimate strength and resilience. The activity of alkaline phosphatase (ALP) and concentrations of Ca and P in the blood serum were estimated. The obtained results indicated that the use of strontium ranelate in orchidectomized rats over a period of 60 days not only inhibited the reabsorbing processes induced by a lack of gonad steroids but also accelerated processes of new bone tissue formation, which improved their mechanical parameters and ultimate strength and maximum elasticity.

5

Wplyw fitazy i chromu w mieszankach z ledzwianem na cechy kosci szczurow

100%

Grela E. R. , Sliwa E. , Radzki R. P. , Puzio I.

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nr 05

273-276

6

Erythrocyte antioxidative enzymes in experimentally induced osteopenia in rats

100%

Radzki R. P. , Bienko M. , Albera E. , Kankofer M.

Bulletin of the Veterinary Institute in Puławy

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2012

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tom 56

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nr 4

EN

The study aimed at the determination of dynamic relationship between mineralisation processes and antioxidative/oxidative status during the development of osteopenia. One hundred and two healthy female Wistar rats at the age of 2 months and initial body weight of 200 g were used in the experiment. The rats were divided into control (CON, n=6), sham operated (SHO, n=48), and ovariectomised (OVX, n=48) groups. Animals from SHO (n=6) and OVX (n=6) groups were sacrificed every week during 8 weeks of the experiment in order to detect dynamic changes in examined parameters. The samples were collected weekly from day 7 to day 56. The femora were examined with the use of DXA (bone mineral density) and pQCT (area, mineral content, volumetric density of trabecular and cortical part of distal femora). The pQCT scans were performed 5 mm from distal end of the tibia. Hie determination of activity of glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) in haemolysates of erythrocytes were performed spectrophotometrically. Obtained data showed wave like changes in both enzyme activities and bone parameters and indicated the importance of the 2nd -3rd and 5th -6th week after surgery as a key moment for bone metabolism and activity of enzymatic antioxidative defence during the development of osteopenia induced by bilateral ovariectomy. The obtained results proved that alterations in activity of GSH-Px and SOD, and pQCT ahead the changes registered by DXA by 7 d.

7

The effects of dietary phytase and 1,25[OH]2D3 on growth and strength of bones in broiler chickens at day 21 of life

100%

Puzio I. , Bienko M. , Radzki R. P.

Journal of Animal and Feed Sciences. Supplement

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2001

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tom 10

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nr 2

8

Bone losses in obese, ovariectomized rats appear to be independent from sclerostin-induced inhibition of the Wnt/β-catenin pathway

88%

Radzki R. P. , Bienko M. , Filip R. , Polak P. , Michalik Wolska J.

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nr 3

9

The effect of fructan-enriched diet on bone turnover parameters in ovariectomized rats under calcium restriction

88%

Topolska K. , Bienko M. , Filipiak-Florkiewicz A. , Radzki R. P. , Cieslik E.

Annals of Agricultural and Environmental Medicine

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2020

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tom 27

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nr 2

10

Bioactive diet components and gastrointestinal tract health

88%

Filip R. , Radzki R. P. , Bienko M. , Sierakowska-Luszczewska I. , Pierzynowski S. G.

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nr 1

11

Gestosc mineralna tkanki kostnej oraz poziom osteokalcyny u kurczat brojlerow w nastepstwie intoksykacji siarczanem glinu

88%

Bienko M. , Radzki R. P. , Puzio I. , Kapica M. , Studzinski T.

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nr 05

562-568

12

Nesfatin-1 prevents negative changes in bone in conditions of developing osteopenia

88%

Puzio I. , Tymicki G. , Pawlowska M. , Bienko M. , Radzki R. P.

Annals of Agricultural and Environmental Medicine

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2020

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tom 27

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nr 1

13

The problem of coccidiosis in broiler chickens and laying hens: Selected control methods and alternative solutions

88%

Fabia K. , Wolski D. , Bienko M. , Radzki R. P. , Szymanczyk S.

Medycyna Weterynaryjna

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2021

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tom 77

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nr 09

14

Fundectomy evokes elevated gastrin and lowered ghrelin serum levels accompanied by decrease in geometrical and mechanical properties of femora in rats

88%

Puzio I. , Kapica M. , Filip R. , Bienko M. , Radzki R. P.

Bulletin of the Veterinary Institute in Puławy

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2005

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tom 49

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nr 1

15

The effect of feeding raw and extruded feed containing soyabean meal on pancreatic juice digestive enzyme activities in young calves

75%

Kapica M. , Valverde Piedra J. L. , Puzio I. , Bienko M. , Szymanczyk S. E. , Radzki R. P.

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tom 14

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nr 1

16

Could fructan sources in strawberry matrix be more effective as a tool for improvement of bone structure than these compounds added to diet alone? - Study on osteopenic rat model

75%

Topolska K. , Radzki R. P. , Filipiak-Florkiewicz A. , Bienko M. , Florkiewicz A. , Cieslik E.

Annals of Agricultural and Environmental Medicine

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2020

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tom 27

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nr 1

17

Influence of snail meat in the diet on mandibular bone loss in male rats: a densitometric, tomographic and morphometric study

75%

Bienko M. , Radzki R. P. , Wolski D. , Debiak P. , Szkucik K. , Ziomek M. , Gondek M.

Medycyna Weterynaryjna

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2018

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tom 74

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nr 11

EN

The study was aimed at determining the effects of diets containing snail meat as the sole protein source, on mandible quality in male Wistar rats. In the experiment, three different snail-based diets were tested and compared with a casein-based control diet. These included snail meat from Helix pomatia, Cornu aspersum maxima and Cornu aspersum aspersum. In all diets, the protein content amounted to 10% (as calculated on a dry weight basis). Forty male Wistar rats with an initial body mass of 50 g ± 2 were randomly allocated to one control and three experimental groups. After 28 days of experimental feeding, the rats were sacrificed. Their mandibles were isolated and investigated by densitometric (DXA), tomographic (pQCT) and morphometric methods. Moreover, the mechanical parameters (ultimate strength and Young’s modulus) of the mandibles were measured. The results revealed that snail meat as the sole source of protein significantly decreased the bone mineral density (BMD) and content (BMC) of the mandibles. Moreover, the tomographic analysis demonstrated that each type of snail-based diet had a negative influence on the bone cortical and trabecular compartments (which was especially noticeable in the decreasing pQCT parameters). The investigation of mechanical resistance of the mandibles also revealed lower values of the ultimate strength and Young’s modulus in the snail-based diet groups, compared with the casein group.

18

Effect of sodium butyrate and Yucca schidigera extract on bone characteristics in growing pigs

75%

Puzio I. , Piedra J. L. V. , Kapica M. , Radzki R. P. , Bienko M. , Pawlowska M. , Szymanczyk S.

Journal of Veterinary Research

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2016

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tom 60

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nr 1

19

Wplyw flutamidu i testosteronu na cechy wytrzymalosciowe, architektoniczne oraz gestosc mineralna kosci udowej i ramiennej kurczat brojlerow

75%

Radzki R. P. , Bienko M. , Puzio I. , Filip R. , Kapica M. , Studzinski T.

Medycyna Weterynaryjna

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2004

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tom 60

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nr 11

1222-1226

20

Wplyw agonisty receptorow adrenegicznych beta2-clenbuterolu na mineralizacje kosci piszczelowej szczura w warunkach ustalonej osteopenii

75%

Radzki R. P. , Bienko M. , Kapica M. , Puzio I. , Dobrowolski P. , Filip R.

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tom 62

|

nr 07

824-826

EN

The purpose of the study was to determine the effect β₂-adrenergic receptor agonist-clenbuterol on tibiae mineralization of female rats with established osteopenia. The experiments were conducted on 30 female 3-months-of-age Wistar rats with an initial body weight of about 250 g. The sham-operation - SHO (n=10) and bilateral ovariectomy - OVX (n=20) were performed. After 60 days of osteopenia induction the ovariectomized rats were divided into a group fed a standard diet (n=10) and a group that received a diet supplied with clenbuterol at a dose of 5 mg/kg. After 14 days of the experiment the tibiae was isolated and tested using a DEXA densitometer, peripheral quantitative computer tomography (pQCT) and three-point bending test. The obtained results proved that a 14 day period of clenbuterol treatment significantly increased mechanical properties content and mineral density, both planar (BMD) and volumetric (vTotBMD) of the tibiae of ovariectomized rats.