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Effects of green tea extract on gastrointestinal tract metabolism, serum parameters and antioxidant status in rats fed a high-fructose diet

100%

Jurgonski A. , Juskiewicz J.

tom 04

55-61

Effects of dietary addition of a low-pectin apple fibre preparation on rats

80%

Fotschki B. , Jurgonski A. , Kolodziejczyk K. , Sojka M.

nr 3

Suppression of postprandial glycaemia by L-arabinose in rats is more associated with starch than sucrose ingestion - short report

80%

Jurgonski A. , Krotkiewski M. , Juskiewicz J. , Billing-Marczak K.

2015

tom 65

nr 1

The aim of this study was to verify the glycaemia-lowering activity of L-arabinose. The experiment was conducted on 3 individual days, each separated by a week. At the beginning of each week rats were subjected to an oral glucose, sucrose or starch tolerance test. Five minutes prior to each test rats were gavaged with water (a control), an aqueous solution of acarbose (a positive control) and L-arabinose. There was no effect of L-arabinose on glycaemia in the glucose tolerance test, whereas it reduced postprandial glycaemia after 15 min of the sucrose tolerance test. In the starch tolerance test, the glycaemia after L-arabinose ingestion was signifi cantly decreased both at time intervals and in total. Inhibition of enzyme activity involved in starch digestion (amylase, maltase) may be suggested as the most probable mechanism responsible for the observed effects.

Dietary chicory inulin-rich meal exerts greater healing effects than fructooligosaccharide preparation in rats with trinitrobenzenesulfonic acid-induced necrotic colitis

61%

Fotschki B. , Jurgonski A. , Fotschki J. , Majewski M. , Ognik K. , Juskiewicz J.

nr 2

The aim of this study was to compare the effects of chicory root inulinrich meal (containing a polyphenolic fraction as well) and pure fructooligosaccharides (FOS) on necrotic colitis induced with trinitrobenzenesulfonic acid (TNBS) in Wistar rats. Both chicory preparations signi cantly reduced the pH value of colonic digesta and favourably lowered the caecal activity of bacterial -glucuronidase as well as the caecal concentration of putrefactive short-chain fatty acids in comparison to the control TNBS rats. In addition, they enhanced the production of total short-chain fatty acid (SCFA pool) and concentration of anti-in ammatory propionic acid in the caecal digesta. Nevertheless, only dieary chicory meal favourably increased the total SCFA concentration and thus decreased the pH value of caecal digesta. The increased caecal SCFA production may explain the observed greater reduction in mucosal necrosis and increased glandular mucosal regeneration in rats fed a diet with chicory root meal. Both chicory preparations bene cially regulated physiological parameters in the lower part of the rat intestinal tract after TNBS-induced colitis, however the dietary treatment with chicory meal showed stronger reduction of mucosal disturbances caused by colitis. Those bene cial effects might be related to the higher polymerization of inulin vs. FOS and to the presence of biologically active compounds in the meal, i.e., phenolic compounds, which had a strong impact on intestinal microbial activity and thus indirectly alleviated mucosal disturbances caused by colitis.