Wyniki wyszukiwania - Biblioteka Nauki

1

Lider Polski Poludniowej

100%

Bugaj R.

|

2003

|

nr 4

5

2

Corpus Hermeticum w historii

100%

Bugaj R.

Kwartalnik Historii Nauki i Techniki

|

2001

|

tom R. 46, nr 4

7--36

EN

The originator and founder of hermetism was the mythical Hermes Trismegistos, a deity of the syncretic Hellenistic religion that came into being through the identification of the Greek god Hermes with the Egyptian god Thot. In later Hellenistsic times, various hermetic writers considered Hermes Trismegistos to have been a historical personnage, a king, prophet and philosopher (physician), as well as author of many widely disseminated writings that made up the so-called Corpus Hermeticum (eithteen separate treatises from the 2nd-4th centuries AD) and the the so-called Emerald Table (Tabula Smaragdina). The Corpus Hermeticum is a collection of treatises of a philosophical, religious, theological as well as theosophical nature. The collection played an important role in the development of the philosophy of alchemy and hermetism, and formed the basis for an alchemist philosophy of nature. There are currently two views among scholars on the origins of hermetism. According to one, hermetism derived directly from Egypt, while according to the other it orginated in Greece. In the years 1945-46 a number of hermetic texts forming part of the now famous gnostic „library“ were discovered in Nag-Hammadi (Chenosboskion) in Upper Egypt. The Coptic texts from Nag-Hammadi date from the middle of the 4th century AD, and according to experts are translations from the Greek. Some authors (R. Reitzenstein and T. Zieliński) have suggested that along with the appearance in Egypt of the Hermetic Books, attributed to Hermes Trismegistos, there also appeared a new god in Egypt, Poimandres, and a new religion was established, hermetism, which competed for influence with Christianity. The present article discusses the main of the hermetic treatises, including Poimandres, which contains an account of the creation of the world. The article also discusses the reasons for the decline of hermetism as a religion and stresses that in spite of this decline the doctrine managed to survive in the form of alchemic hermetism, which played an important role in the culture of the Renaissance. The article also cites the voluminous work by W. Scott and A.S. Ferguson (1924-1936), and A.D. Nock and A.-J. Festugiere (1945-1964), which contains contemporary, English and French, commentaries on and translations of the Corpus Hermeticum texts.

3

Spotkajmy sie w Zakopanem

100%

Bugaj R.

|

2003

|

nr 4

14

4

Renesansowy poemat o soli kamiennej : Adam Schröter "Salinarium Vieliciensium descriptio"

100%

Bugaj R.

Kwartalnik Historii Nauki i Techniki

|

1999

|

tom R. 44, nr 2

61--94

EN

The fame of the Wieliczka salt mine in Poland, one of the most ancient and richest salines in the world, goes back to the thirteenth century. In the sixteenth century Wieliczka became the focus of interest of many scholars and writers, both in Poland and abroad. It was also in that period that many descriptions of the Wieliczka and Bochnia salt mines appeared, e.g. by Konrad Celtis (Celtes) (1459), Wawrzyniec Korwin (1460-1527), Stanisław Tarnowski ( 16th century), Jodok Willich ( 1501-1552), Joachim Wadian (1484- 1551), Joachim Retyk (1514-1574), as well as many others. The article discusses a poem by the Silesian writer Adam Schröter (1525-1572), entitled Salinarum Vieliciensium descriptio, first published in 1553, and then reissued in 1564. As a poet and alchemist, Schröter gave an interesting account of his visit to the Wieliczka mine. He also presented a short natural history of rock salt, introducing into his poem motifs from the hermetic-alchemist teachings of Theophrastus Paracelsus (1493- 1541), of whom he was a fervent follower. As an eye-witness acccount of the Wieliczka mine, Schröter's work is of great histrorical value. It combines a mythological-hermetic guise with a realistic account of the facts described. Adam Schröter's poem about salt, which was known and read throughout Europe at the time, merits inclusion among the most valuable sources on the history of one of the most famous salt mines.

5

Homocysteine, cysteine and gluthatione in epileptic patients treated with antiepileptic drugs

38%

Bugaj R. , Urbanska N. , Dorszewska J. , Sniezawska A. , Przedpelska-Ober E. , Kozubski W.

|

nr 1

EN

Today, epilepsy is regarded as the most common neurological disease. AEDs pharmacotherapy, used to treat patients with epilepsy affect plasma concentrations of sulfur amino acids: Hcy, Cys and GSH. These are the main intracellular thiols, whose anabolic and catabolic pathways are closely linked. Through transsulfuration of Hcy arises Cys, who further participates in the synthesis of GSH. It has been shown that the increase of plasmatic Hcy in patients with epilepsy taking AEDs can be affected by a number of factors including diet, type of pharmaceutical preparations taken, the duration of treatment, and genetic factors. The study group consisted of 63 patients with idiopathic epilepsy, 28 women and 35 men, aged from 18 to 65. Among patients with epilepsy 55 people, 24 women and 31 men, aged from 18 to 65 were treated with various AEDs, and 8 patients, 4 women and 4 men, aged between 18 and 65 were before the inclusion the anticonvulsant therapy. A preliminary analysis in our studies was conducted on 38 people from the control group, 28 women and 10 men, aged from 22 to 67, without symptoms of dementia or any other neurological disorders. The concentration to sulfur amino acids (Hcy, Cys, GSH) in plasma has been identified by HPLC (high performance liquid chromatography) with electrochemical detection. The analysis was performed in Thermo Hypersil BDS C18 column (250x4, 6x5 µm) using phosphate buffer with 12.7% acetonitrile as mobile phase for the determination of Hcy and GSH, and phosphate buffer with 10% acetonitrile as buffer mobile phase for the determination of Cys. Studies show that AEDs pharmacotherapy in patients with epilepsy leads to a significant increase in Hcy- treated in polytherapy, especially in the application of VPA and the long-term treatment. In addition, in patients with epilepsy treated with VPA in monotherapy, plasma Cys concentration is significantly reduced. Moreover, it was observed that long-term AEDs treatment and mild HHcy (Hcy>16 µmol/l) in patients with epilepsy leads to a significant increase in GSH concentration. It can be assumed that patients with epilepsy using AEDs are exposed to high oxidative stress, which is an index for the observed higher concentrations of GSH, the main intracellular antioxidant. It also seems that only the combined supplementation of vitamins B and FA in patients with epilepsy treated with AEDs may contribute to the effective regulation of Hcy- the risk factor for vascular diseases.