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EN
The aim of the study was to estimate the efficacy of Streptovac vaccine in controlling Streptococcus suis infections in field conditions in swine, Streptovac vaccine contains no less than 8.5 × 108 inactivated cells of S. suis type 2 and a similar number of S. suis type 1/2. The vaccine includes two adjuvants: aluminum hydroxide and mineral oil (Emulsigen). The experiment was performed on 3 farms: S, H and P with total of 4,400 sows (3,000, 1,100 and 300 sows). Clinical symptoms of streptococcosis occurred mainly among weaners between 7-8 weeks of age. Clinical signs associated with changes in the central nervous system were mainly observed. Losses due to streptococcosis in farms varied from 4-6%. Streptovac was used to immunize pigs from 3 different experimental groups in each farm. In farm S - 1,462 farm P - 447 and farm H - 1,307 animals were vaccinated. Vaccination was performed just before weaning and 3 weeks later; 2 ml of vaccine was applied i.m. One group of pigs in each farm served as the control. The parameters of production in every experimental group were compared with the results in the control group in order to evaluate the efficacy of the vaccine. The following criteria were evaluated: percentage of weaners with clinical signs of infection, percentage of pigs which died from streptococci with body weight on the day of weaning and moving from weaning house to fattening house, mean body weight gains during the 2 month period of observation. The analyzed results indicated a significant reduction in all farms in the average number of pigs with typical signs of infection in the central nervous system: in farm S - 4.58% in the experimental group and 7.92% in the control one; in farm P - 6.04% and 9.33% and in farm H - 3.74% and 6.56%. A similarly significantly lower mortality rate in was observed in the vaccinated pigs. The average death rate for control groups in farm S - was 4.87% and for experimental groups 1.64%; in farm P - 6.00% and 3.13% and in farm H - 4.17% and 2.06%. The differences between body weight gains among vaccinated and control pigs were not significant. To summarize, Streptovac vaccine used in farms where streptococcosis is caused by field strains cross-reacting with vaccine strains ensures a significant reduction of losses caused by S. suis.
EN
The aim of the study was to determine ceftiofur sensitivity of Streptococcus suis isolated from pathologically altered brains and joints of pigs with streptococci compared with the efficacy of treating two diverse forms of Streptococci infections in pigs (neurological and joint infections) with the same antibiotic depending on the severity of the clinical signs. The study was carried out on two farms - “P” and “W”. The results of the in vitro study demonstrated that 98.5% of the 67 Streptococcus suis isolates were sensitive to ceftiofur. Only one isolate from the joint was medium sensitive. The efficacy of the treatment (in vivo studies) in stage I of both the neurological form (apathy, auricular symptoms) and articular form (lameness, lack of evident swelling or mild swelling of one joint) of streptococcal disease proved to be significantly high on the farms (between 90.3-100%). The efficacy of treating more severe cases was lower and the course treatment was also longer. The proportion of recoveries in the neurological form (increase of body temperature above 41.0°C and in coordination) of streptococcal infections ranged from 66.7% on farm “W” to 72.8% on farm “P”. The results obtained in analogous groups of animals with moderately severe joint infections (lameness and evident swelling of one joint) ranged from 47.7% on farm “W” to 56.4% on farm “P”. The proportion of the recovered animals affected with neurological symptoms of stage III (lateral position, rowing movements) was 44.4% on “P” farm and merely 28.6% on farm “W”. A positive outcome of polyarthritis treatment during the three week observation period was noted in 10.7% of the cases on farm “P” and in only one weaner (4.5%) on farm “W”. Treatment failures of the articular form of streptococcal infections compared to the neurological form were not estimated in terms of losses but rather as chronic inflammations persisting beyond the observation period and requiring further therapeutic procedures or, more frequently, culling of the animals. It may be concluded that ceftiofur is characterized by its significant efficacy in treating clinical symptoms which have been diagnosed early and cured. The in vivo studies, where there was an intensification of the disease data, indicated the antibiotic’s efficacy and good penetration into joints and cerebrospinal fluid during inflammation. Speed in diagnosing and treating an ongoing S.suis infection plays a critical role in the efficacy of the therapy.
EN
The aim of the study was to present the reasons for the emergence and an overview of new bacterial infections in freshwater fish diagnosed in Poland over the last several years. One of the main reasons is ecological changes in freshwater ecosystems as a result of the degradation of these environments. The progressive degradation of these ecosystems is largely due to human activity associated with the development of civilization, which results in the production of greater amounts of sewage of different origin. Also some factors independent of human activity have a major influence of degradation and variability in freshwater environments; for example climate change, geographical conditions and the effects of natural disasters. In fish farming conditions, additional factors contributing to the emergence of new diseases/pathogens are the use of antibiotics and disinfectants. Moreover, the introduction of new fish species carries many risks. For several or even a dozen years, some new infections in freshwater fish cultured in Poland have been diagnosed. They are caused by bacteria which were not previously known as fish pathogens, or infections formerly diagnosed in many other countries, while in Poland they emerged relatively recently. The first group includes infections caused by Acinetobacter lwoffii, A. johnsonii and Shewanella putrefaciens. Both cyprinids as well as salmonids fish cultured in Poland are sensitive to these infections. Among these microorganisms, S. putrefaciens are most frequently diagnosed, causing losses of up to 20% of the infected population. The second group includes bacteria from the genera Serratia and Streptococcus. These microorganisms primarily affect salmonids. In the case of infections Serratia spp, losses may reach up to 35%. In populations of fish infected with Streptoccoccus spp. losses are between 5% and 15%. Data presented in this article suggest the need for a new approach by diagnosticians to identify fish diseases. Currently, laboratory diagnosis must take into account not only the presence of bacteria well known as pathogens of fish as potential etiological factors of disease, but also those less well-known in Poland or completely new ones.
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