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EN
Saliva is a gel resembling liquid, that acts almost as an organic tissue [1]. Saliva influences oral health through its non-specific physico-chemical properties [2]. It is composed of secretions from parotid, submandibular and sublingual glands, and smaller contributions come from minor salivary glands (e.g. palatal and labial). Saliva contains a number of proteins and polypeptides [2]. One of them is statherin a multifunctional 43-amino acid residue phosphominiprotein, containing vicinal phosphoserines at 2 and 3 positions and seven residues of tyrosine (Fig. 1) [7]. The relevant structural feature of statherin is N-terminal helix segment connected to a long poly--L-proline type II segment, which is followed by a short extended structure [14]. The gene for statherin is believed to be a single-copy gene and has been mapped to human chromosome 4q11-13 [20]. The statherin variants are SV1, SV2 and SV3 which comprise approx. 30% of the statherin family (Fig. 6). The ratios of statherin : SV1 and SV2 : SV3 are in both cases approx. 3 : 1. Statherin and SV2 are products of two different transcripts found in each of the major salivary gland. The variants SV1 and SV3 are derived by post-translational processing of statherin and SV2 [22]. Statherin is a multifunctional molecule that shows a high affinity for calcium phosphate minerals such as hydroxyapatite. It takes part in the calcium and phosphate transport during secretion in the salivary glands, is responsible for the protection and recalcification of tooth enamel, promotes selective initial bacterial colonization of enamel, and functions as a boundary lubricant on the enamel surface [38, 39]. Satherin levels of concentration in saliva could be in relation with the precancerous and cancerous lesions of the oral cavity [38]. The understanding of a profile and role of statherin has become important in medicine as the peptide could play a protective effect in oral cavity. However, the role and the functions of this peptide are still not well-know [38].
PL
W pracy oceniono poziom magnezu w ślinie osób chorych na stwardnienie rozsiane. Badanie biochemiczne wykonano również w grupie kontrolnej. Na podstawie przeprowadzonych badań stwierdzono obniżony poziom magnezu w ślinie osób chorych w porównaniu z osobami zdrowymi. Wyniki badań mogą sugerować pewien związek ze stwardnieniem rozsianym.
EN
In this study the level of magnesium in saliva of patients with multiple sclerosis was analyzed. Biochemical analysis of saliva was carried out in the control group, too. On the basis of our examination the lower level of magnesium in saliva of SM patients in comparison to control group was observed. The results of our examination may suggest that lower magnesium concentrations in saliva could be connected with multiple sclerosis.
EN
This paper presents the results of a study of the friction coefficient of titanium–elastomer couple. The study was carried out with a view to potential future utilization of its results for constructing retentive elements of implanted prostheses. Changes in the friction force were recorded while removing titanium specimens placed between two silicone counter specimens made of Ufi Gel. The influence of the titanium specimen movement speed in relation that of to the counter specimens and the influence of clamping force on the friction force were assessed. Additionally, the surface roughness of titanium specimens differed; in one case, titanium was coated with polyethylene. The effect of introducing artificial saliva between the cooperating surfaces on the friction force and friction coefficient was analyzed as well. Based on the characteristics recorded, the possibilities of shaping the friction coefficient have been assessed, since it is the friction coefficient that determines effective operation of a friction couple through increasing the titanium specimen roughness. The artificial saliva being introduced between the specimens reduces considerably the friction coefficient through a change of the phenomenon model. An increase in the pressure force for the specimens of high roughness entails a reduction of the friction coefficient. The study carried out allows us to identify the roughness parameters, which in turn will enable obtaining the prescribed retention force for friction/membrane couplings.
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