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Location, location, location: the role of brain atlases and spatial integration of multimodal imaging data in whole brain mapping projects

100%

Majka P.

2019

tom 79

nr Suppl.1

Spatial integration of multimodal imaging data is a common denominator of all whole brain mapping projects. This process requires robust image registration pipelines, high‑ quality 3D brain atlases, as well as, scalable methods for quantitative image analysis. During the talk, I will discuss the computational challenges behind these components, exemplify ways of addressing them, and discuss requirements for setting up one’s own computational pipeline. I will also demonstrate how these novel computational methods and approaches could provide a deeper understanding of the structure and function of the central nervous system, especially in the context of high-throughput and large‑scale experiments. The talk will be complemented with examples of specific neuroscientific findings arising from whole brain mapping projects in rodents and primates, highlighting synergy between the computational and experimental aspects in these projects.

Microstructural changes of expansive clays during dehydration caused by suction pressure - a case study of Miocene to Pliocene clays from Warsaw (Poland)

100%

Wójcik E. , Trzciński J. , Łądkiewicz-Krochmal K.

2019

tom Vol. 69, no. 3

465--488

This paper presents the qualitative and quantitative characteristics of microstructures of Neogene clays from Warsaw, Poland. Scanning Electron Microscope (SEM) studies were used for the microstructural analysis of natural clays and clay pastes. Qualitative microstructural changes were observed: from a honeycomb microstructure for the initial clay paste to a turbulent microstructure for the dried paste. It was also noticed that water loss caused by the increase of the suction pressure had a significant impact on the microstructural transformations. Significant changes in the quantitative values of the pore space parameters were also observed. Increase of suction pressure and water loss caused a decrease in porosity and changes in the values of morphometric parameters, such as pore distribution; for example, a significant increase of the number of pores of 0−10 μm size and changes in the geometric parameters of the pore space were noticed with the increase of suction pressure. The pore space with larger isometric pores was modified into a pore space with the dominance of small anisometric and fissure-like pores. The increased degree of anisotropy from a poorly-oriented to a highly-oriented microstructure was also observed. After rapid shrinkage the reduction in the number of pores, maximum pore diameter, and total pore perimeter was recorded. The process of rapid water loss induced the closure of very small pores. A similar effect was observed during the increase of the suction pressure, where the closure of pore space of the clay pastes was observed very clearly.

Supermolecular structure, morphology and physical properties of urea-urethane elastomers

80%

Ryszkowska J.

Polimery

2012

tom T. 57, nr 11-12

775-785

Urea-urethane elastomers from polyesterdiol, 4,4'-diphenylmethane diisocyanate (MDI) and dicyandiamide were examined. Their structure was analysed using atomic force microscopy, and the obtained images underwent quantitative analysis. FT-IR spectroscopic analyses were performed, and the phase separation degree was calculated using the results. The structure was also estimated via indirect methods with the use of thermal analysis DSC and TGA. Mechanical and abrasive wear properties were also tested. As a result of the analyses, a linear dependence was found between the size of the hard domain agglomerates and the analysed properties of PUR materials, such as the glass transition temperature of the soft phase, the temperature of the maximum speed of the hard phase's degradation, density, hardness, tensile strength and strain.

Badano elastomery uretanowo-mocznikowe wytworzone z poliestrodiolu, 4,4'-difenylometanodiizocyjanianu (MDI) i dicyjanodiamidu. Z zastosowaniem mikroskopii sił atomowych oceniano ich struktury nadcząsteczkowe a otrzymane obrazy poddano analizie ilościowej. Zarejestrowano widma FT-IR, a na ich podstawie obliczono stopień separacji fazowej. Strukturę oceniano też metodami pośrednimi wykorzystując analizę termiczną DSC i TGA. Określono właściwości wytrzymałościowe i zużycie ścierne otrzymywanych elastomerów. Stwierdzono liniową zależność pomiędzy rozmiarem aglomeratów domen twardych a temperaturą zeszklenia fazy miękkiej, temperaturą maksymalnej szybkości degradacji fazy twardej, gęstością, twardością, wytrzymałością na rozciąganie i odkształceniem trwałym.