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Content available remote Ocena gęstości mineralnej kości studentów w wieku 20-29 lat
75%
PL
Celem pracy była ocena wyników pomiaru gęstości mineralnej kości (BMD) w wybranej grupie studentów Akademii Wychowania Fizycznego we Wrocławiu. Badaniami objęto 423 studentów, w tym 298 kobiet i 125 mężczyzn w wieku od 20 do 29 lat. U wszystkich badanych dokonano pomiaru BMD okolicy kręgosłupa lędźwiowego w projekcji przednio-tylnej dla kręgów L2-L4. Obniżone wartości gęstości mineralnej kości, mogące świadczyć o wystąpieniu osteopenii lub osteoporozy, zaobserwowano u 68 osób. Ponadto stwierdzono, iż średnia wartości BMD w grupie mężczyzn jest istotnie wyższa niż w grupie kobiet (p=0,0004).
EN
The goal of the study was to evaluate the results of the bone mineral density (BMD) measurements on a group of the students of the Academy of Physical Education (AWF) in Wroclaw, Poland. The examined groupof 423 students was composed of 298 women and 125 men, in age of 20-29 years. The BMD was measured in the region of the L2-L4 lumbar spine. In 68 students low BMD values were observed, possibly indicating osteopeny or osteoporosis. Moreover, it was observed that the mean BMD value in men is significantly higher (p=0,0004) than in women.
EN
Lumbar disc degeneration is characterised radiologically by the presence of osteophytes, endplate sclerosis, and disc space narrowing. Our study was designed to assess anterior lumbar osteophytes, disc space narrowing, end plate sclerosis, and bone mineral density (BMD) in the lumbar vertebrae and femoral neck of elderly men. A total of 1000 men, aged between 71 and 90 years, were invited to participate in the study. BMD was assessed at the spine and femoral neck using dual energy X-ray absorptiometry (DXA). We examined the relationship with the degree of lumbar spinal and femoral neck deformity by using the Z-score. Lateral and anterioposterior spinal radiographs were evaluated for features of lumbar disc degeneration. The observers consisted of a consultant physical therapist, a radiologist, and anatomists who together studied the series of radiographs. Anterior lumbar osteophytes (grade 0–3), end-plate sclerosis, and disc space narrowing (grade 0–2) were evaluated. The Pearson correlation test was used to determine the association between radiographic features, the lumbar mineral density (LBMD), and femoral neck mineral density (FNBMD). In all, 90.6% of lumbar vertebral levels showed evidence of anterior osteophytes, 87.5% showed evidence of end plate sclerosis, and 68.2% of disc space narrowing. Additionally, there was a strong negative correlation in terms of age at the femoral neck, though not at the spine. On the other hand, there was a significant correlation between osteophyte grade and end plate sclerosis at the spine. In our study, the radiographic features of lumbar disc degeneration, anterior osteophytes, and end plate sclerosis were associated with an increase in BMD at the spine. (Folia Morphol 2010; 69, 3: 170–176)
EN
Background. This study analysed the correlation between characteristic dietary and non- dietary factors of fracture risk in women and mineral density of bone tissue (BMD). Material and methods. The study involved examination of 172 women, aged between 32 and 59. Calcium intake from a daily diet was determined with the use of the semiquantitative food consumption frequency method. The physical activity of the women was expressed in MET-minutes/week. BMD was determined by double-energy X-ray absorptiometry (DXA). The frequency of bone fracture and osteoporosis risk factors was determined and a 10-year risk of fracture (RB-10) was individually diagnosed according to the WHO and IOF criteria (2007). A high level of fracture risk (RB-10 > 14%) was assumed according to the Johnell's algorithm [2005], Results. The most frequent factors of fracture risk in women included: bone pains (76% of the total sample), inadequate calcium intake (43%), smoking (24%), previous fractures (24%), incidence of chronic diseases (22%), menstrual disorders (19%), family history of osteoporosis (17%), low physical activity (15%) and the incidence of thyroid disorders (10%). 85% of women had at least one factor of 10-year absolute risk of fracture. None of the examined women consumed a sufficient amount of calcium and the average calcium intake level was low (median of about 400 mg/day). Bone mineral density did not reveal any relationship with current intake of calcium by women, but depended on the consumption of dairy products in the past. Conclusions. Daily consumption of dairy products in childhood and in the school period was conductive to a higher mineral density of bone tissue in women. Advanced age and the occurrence of menstrual disorders were conductive to a lower mineral density of bone tissue in women. Women with low bone mineral density (lower BMD tertile) more frequently used supplementation with preparations containing calcium (25%) and more often had at least one RB-10 risk factor (93% of the sample).
PL
Wstęp. Analizowano współzależność pomiędzy charakterystycznymi żywieniowymi i pozażywieniowymi czynnikami ryzyka złamania kości u kobiet a gęstością mineralną tkanki kostnej (BMD). Materiał i metodyka. Badaniami objęto 172 kobiety w wieku od 32 do 59 lat. Metodą półilościowej częstotliwości spożycia żywności określono spożycie wapnia z dziennej diety. Aktywność fizyczną kobiet określono w MET-minutach/tydzień. Metodą dwuwiąz- kowej absorpcjometrii rentgenowskiej (DXA) oznaczano BMD. Oceniono częstość występowania czynników ryzyka złamania kości i osteoporozy oraz zdiagnozowano indywidualne 10-letnie zagrożenie złamaniem kości (RB-10) według kryteriów WHO i IOF (2007). Wysoki poziom zagrożenia złamaniem kości (RB-10 > 14%) przyjęto według algorytmu Johnella [2005]. Wyniki. Najczęściej występującymi czynnikami ryzyka złamania kości u kobiet były: bóle kostne (76% próby ogółem), niedostateczne spożycie wapnia (43%), palenie papierosów (24%), przebyte złamania (24%), występowanie chorób przewlekłych (22%), zaburzenia miesiączkowania (19%) i osteoporoza w rodzinie (17%), mała aktywność fizyczna (15%) i występowanie chorób tarczycy (10%). Co najmniej jednym czynnikiem 10-let- niego bezwzględnego ryzyka złamania charakteryzowało się 85% kobiet. Żadna z badanych kobiet nie spożywała dostatecznej ilości wapnia i niski był przeciętny poziom jego spożycia (mediana ok. 400 mg/dzień). Gęstość mineralna tkanki kostnej nie miała związku z aktualnym spożyciem wapnia przez kobiety, lecz zależała od spożycia produktów mlecznych w przeszłości. Wnioski. Codzienne spożywanie produktów mlecznych w dzieciństwie i okresie szkolnym sprzyjało większej gęstości tkanki mineralnej kostnej kobiet. Mała gęstość mineralna tkanki kostnej kobiet wiąże się ze starszym wiekiem i występowaniem zaburzeń miesiączkowania. Kobiety wyróżniające się małą gęstością mineralną tkanki kostnej (dolny tercyl BMD) częściej stosowały suplementację preparatami zwierającymi wapń (25%) i częściej były obciążone co najmniej jednym czynnikiem ryzyka RB-10 (93% próby).
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2010
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tom 54
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nr 4
EN
The influence of sex on bone mineral density (BMD) and the bone mineral content (BMC) have been analysed in selected bones of the thoracic and pelvic limbs of African ostriches. The examination was conducted with the use of a densitometer, using the technology of affinited beam of X-ray and the programme for animal research. It was shown that the analysed bones of ostrich skeleton differed significantly regarding the BMD and BMC. Significantly higher values of both parameters were recorded in case of the bones of the pelvic limb in comparison with the bones of the thoracic limb. A central part of the shaft of the tibio-tarsal bone and its proximal end (the pelvic limb) were characterised by the highest values for both BMD and BMC, whereas for the ulnar and radial bones (the thoracic limb) the lowest values were obtained. The study also demonstrated that males showed a significantly higher BMD and BMC values than females referring to the pelvic bones, i.e. the tibio-tarsal bone. For further study aiming at monitoring changes in BMD and BMC during the growth and development of ostriches from hatching till the 14th month of life, the use of densitometer intravitally is recommended.
EN
Retinoic acid-induced osteoporosis (RBM) is one of the most common causes of secondary osteoporosis. This study tested the anti-osteoporetic effect of quercetin in RBM-induced bone loss model (RBM). After 14-day supplementation of 13cRA to induce RBM, rats were administered with quercetin (100 mg/kg) or alendronate (40 mg/kg). We analysed changes in body and uterine weight of animals, femoral geometric characteristics, calcium and phosphorus content, bone weight index, bone hystology, bone mineral density (BMD), markers of bone turnover, lipid peroxidation, glutathione levels and SOD, CAT activity of liver, kidney spleen, and ovary as well as biochemical and haematological variables. In comparison to the control RBM rats, the treatment with quercetin increased bone weight index, BMD, osteocalcin level, femoral geometric characteristics, calcium and phosphorus content in the 13cRA-induced bone loss model. Histological results showed its protective action through promotion of bone formation. According to the results, quercetin could be an effective substitution for alendronate in 13cRA-induced osteoporosis. Good therapeutic potential of quercetin on rat skeletal system is based partly on its antioxidant capacity and estrogenic activity.
EN
The bone mineral density BMD and content BMC were analysed in the tibiotarsal bones of ducks in the postnatal development as influenced by age and sex. One hundred birds from the nesting till the slaughtering maturity were included in the experiment. The analysis was conducted using a densitometer, Norland - Excell Plus and pQCT computed tomography, XCT Research SA Plus. The statistical analysis was conducted using the Kruskal-Wallis one-way analysis of variance (age) and the U-Mann -Withney test (sex). All calculations were performed in Statistica 9.0 (StatSoft, Inc. Tulsa, USA), at P ≤ 0.05. Two-factor analysis of variance ANOVA was applied and Pearson’s correlation coefficients were calculated. The densitometer research showed that BMD and BMC increased in the postnatal development for both sexes. The volumetric bone mineral density vBMD analysis using computed tomography showed that volumetric bone mineral density vBMD of the middle of the diaphyses in situ gradually attenuated during the postnatal development both in males and females, i.e. from 620 mg/cm3 (2 wk) to 500 mg/cm3 (8 wk). The biggest vBMD loss was observed in the diaphyses of females in 4 and 6 wk (r = - 0.63 and r = - 0.79; P ≥ 0.05). The BMC decrease was observed in the proximal metaphyses between 4 and 6 wk for both sexes, r = - 0.52 (males), r = - 0.53 (females); P ≤ 0.05. The gradual loss may be the cause of deformities and fractures of the tibiotarsal bones observed from 4 wk in particular bone sections of both sexes. The achieved results may constitute a helpful source of information for water poultry breeders to prevent limb diseases.
PL
Celem pracy była ocena aktywności fosfatazy zasadowej (Fz) i kwaśnej (Fk) w surowicy szczurów po usunięciu jajników oraz po zastosowaniu estrogenowej terapii zastępczej. Oceniono również związek pomiędzy gęstością mineralną kości (BMD) żuchwy i kręgosłupa a parametrami metabolizmu kostnego. Stężenie fosfatazy zasadowej i kwaśnej było najwyższe u zwierząt z niedoborem estrogenów, a podawanie 77-ß estradiolu znamiennie obniżyło poziom badanych markerów. Stwierdzono również istotną ujemną korelację Fz i Fk z BMD żuchwy i kręgosłupa.
EN
The aim of this study was to evaluate the activity of alkaline (ALP) and acid (ACP) phosphatase in the blood serum of rats after ovariectomy and with estrogen replacement therapy. The relationship between mandible and spine bone mineral density (BMD) and parameters of bone remodeling was also estimated. The concentration of serum total alkaline and acid phosphatase was higher in the rats with estrogen deficiency, and statistically lower in rats administering 17ß-estradiol. ALP and ACP levels were correlaterd significantly negative with mandible and spine BMD. Carried out examinations confirmed increasing bone resorption during experimental postmenopausal osteoporosis.
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