Wyniki wyszukiwania - Biblioteka Nauki

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DIPSACUS FULLONUM L. LEAVES AND ROOTS - IDENTIFICATION OF THE COMPONENTS OF THE ESSENTIAL OILS AND ALPHA-AMYLASE INHIBITORY ACTIVITIES OF METHANOLIC EXTRACTS

100%

Witkowska-Banaszczak E.

Acta Poloniae Pharmaceutica - Drug Research

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2018

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tom 75

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nr 4

951-957

EN

Abstract: Dipsacus fullonum L. syn. D. sylvestris is a biennial plant from the Dipsacaceae family. It grows in Europe, North Africa and Asia Minor. It has been used in folk medicine mainly to treat Lyme disease. This study was undertaken to identify and compare the components of the essential oils from dried and fresh roots, which are usually applied as medicinal agents, as well as those of the essential oils from dried and fresh leaves, used less frequently. The essential oils from the Dipsacus fullonum leaves and roots were analysed by the GC and GC-MS analysis. 18 components were identified in the essential oil from the fresh leaves, whereas 37 were recognised in the oil from the dried leaves; 10 components were identified in the essential oil from the fresh roots and 40 in that from the dried roots. Phytol was the main component in the essential oil from the leaves, whereas n-hexadecanoic acid was predominant in the roots. The α -amylase inhibition has been proven for methanolic extracts of D. fullonum leaves and roots. The strongest activity was demonstrated by the extract from fresh leaves of D. fullonum and showed an effect about one hundred times weaker than acarbose.

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Effect of the solvent on the extraction of polyphenols from distillery stillage and on their antioxidant activity

88%

Mikucka W. , Zielińska M.

Acta Universitatis Lodziensis. Folia Biologica et Oecologica

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2021

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tom 17

54-62

EN

The increase in the costs of storage and disposal of post-production residues has resulted in the search for new directions for their recycling, which is closely related to the necessity of protecting the natural environment and promoting a circular economy. Moreover, the apparent interest shown by the food market in raw materials with high antioxidant activity implies an increasing use of by-products. The objective of the study was to determine the effect of the type and concentration of the solvent on the efficiency of extracting polyphenols from distillery stillage as well as their antioxidant activity by using several solvents: methanol:water (70:30 v/v), methanol:water (100:0 v/v), ethanol:water (70:30 v/v) or ethanol:water (100:0 v/v). The DPPH radical method was used to determine the antioxidant activity of the obtained extracts. The normalised variable (NV) and statistical measure (MS) were determined, based on which the effectiveness of the solvents was evaluated. The highest polyphenolic content and the antioxidant activity were obtained by using ethanol:water (70:30 v/v) as a solvent in the extraction of polyphenolic compounds from distillery stillage.

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Chemical composition and anti-inflammatory and anticancer effects of methanolic extract of Arum palaestinum spadices

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Habash B. , Albarghouti G. , Naseef H. , Sabri I. , Enaya M. , Al-Rimawi F.

Acta Agrobotanica

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2024

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tom 77

4

Phytochemistry and antimicrobial property of fruits of Chrysophyllum albidum against selected clinical isolates

75%

Adeleye S. A. , Orji C. C. , Braide W. , Akaluka C. K.

International Letters of Natural Sciences

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2016

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tom 55

EN

The antimicrobial activity of methanolic and aqueous extracts of Chrysophyllum albidum fruits was investigated against clinical isolates(Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia and Candida albicans). Qualitative phytochemistry of the plant indicated that the plant contained Flavonoids, Steroids, Alkaloids, Tannin, Anthraquinone and Cardiac glycosides while Saponins were reported absent. The maximum activity of the aqueous extracts in the test isolates was observed on Staphylococcus aureus, which showed clear zones with diameters of 24.0mm, 20.0mm and 16.5mm at concentrations of 100mg/ml, 50mg/ml and 25mg/ml respectively while it had low activity on Klebsiella pneumonia, with clear zones of inhibition of 15.0mm, 12.0mm and 10.5mm at same concentrations. On the other hand, Methanolic extracts activity on Staphylococcus aureus produced clear zones of 21.0mm, 17.5mm and 12.0mm at concentrations of 200mg/ml, 100mg/ml and 50mg/ml respectively as its best activity while the it had least observed activity on Klebsiella pneumonia with clear zones of 14.0mm, 11.5mm and 10.5mm at same concentrations. The aqueous extracts had greater activity than the methanolic extracts at same concentrations. Therefore, the fruit of the plant can be a good source of remedy in phytomedicine.

5

Toxic effects of the crude methanolic extract of Austroplenckia populnea leaves and fractions on the growth of Spodoptera frugiperda

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Pires W. , Arini L. E. S. , Menezes A. C. S. , Jesus F. G. , Rocha E. C. , Araujo M. S.

Acta Agrobotanica

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2023

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tom 76

6

Berberine from Argemone mexicana L exhibits a broadspectrum antibacterial activity

75%

More N. , Kharat K. , Kharat A.

Acta Biochimica Polonica

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2017

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tom 64

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nr 4

653-660

EN

The Argemone mexicana L, commonly found on desolate land in the Marathwada region of Maharashtra state, India, has been used for treating oral cavity infections. We sought to investigate the antimicrobial potential of A. mexicana L. In this study, cold aqueous and methanolic extracts were prepared from the A. mexicana L leaves. These extracts were tested for their antibacterial activities against selected bacterial isolates. The antibacterial activity and MICs were tested using the agar well diffusion method and broth dilution method, respectively. The cold aqueous and methanolic extracts of A. mexicana L leaves inhibited growth of clinical isolates of Staphylococcus aureus, Bacillus cereus, Escherichia coli and Pseudomonas aeruginosa.The antibacterial potentiality of A. mexicana L extracts was compared with Streptomycin - the reference antibiotic used in this study. The active ingredient of antibacterial potentiality within the A. mexicana L extract was purified and characterized by TLC, HPLC and NMR analysis. Structural elucidation of Berberine and its bioactivity both, from the A. mexicana L and commercial preparation, is investigated.

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The effect of methanolic extracts of selected plant species on feeding of large pine weevil Hylobius abietis (L.) beetles

63%

Korczynski I. , Kuzminski R.

Acta Scientiarum Polonorum. Silvarum Colendarum Ratio et Industria Lignaria

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2009

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tom 08

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nr 1

EN

The aim of the study was to verify whether methanolic extracts prepared from plants of 26 selected species contained substances reducing feeding of Hylobius abietis beetles on shoots of Pinus sylvestris. Experiments were conduced under laboratory conditions. A statistically significant reduction in the size of damage was recorded on pine twigs treated with methanol extracts of leaves of Trifolium repens, Lupinus polyphyllus, Robinia pseudoacacia, Tanacetum vulgare, Nicotiana tabacum, Sambucus nigra, Convallaria majalis and Lycopersicon esculentum. Probably the strongest antifeedants were methanolic extracts of leaves of Lupinus polyphyllus, Robinia pseudoacacia and Convallaria majalis.

PL

Celem badań było sprawdzenie czy ekstrakty metanolowe wykonane z 26 gatunków roślin zawierają substancje zmniejszające żerowanie chrząszczy Hylobius abietis na gałązkach Pinus sylvestris. Badania zostały wykonane w warunkach laboratoryjnych. Wykazano statystycznie istotne zmniejszenie wielkości uszkodzeń na gałązkach sosnowych traktowanych wyciągiem metanolowym z liści Trifolium repens, Lupinus polyphyllus, Robinia pseudoacacia, Tanacetum vulgare, Nicotiana tabacum, Sambucus nigra, Convallaria majalis, Lycopersicon esculentum. Prawdopodobnie najsilniejszymi antyfidantami były wyciągi metanolowe z liści Lupinus polyphyllus, Robinia pseudoacacia i Convallaria majalis.

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Antimicrobial activity of methanolic root extract of Decalepis hamiltonii Wight and Arn

63%

Prakash P. , Manivasagaperumal R.

International Letters of Natural Sciences

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2016

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tom 56

EN

The present study was quantitative analysis and antimicrobial activity of petroleum ether, chloroform, ethyl acetate, methanol root extracts. The gram positive and gram negative bacterial and fungal species by the disc diffusion method at various concentration (250μl-1000μl). The results was present in the phenolic and flavonoid content compared to extracts. All the root extract against to Bacillus subtilis and Streptococcus pyogenes and fungal species Candida albicans at highest inhibition at concentration of methanolic root extract of zone formation. The preliminary studies on Decalepis hamiltonii root extract exhibited their antimicrobial potential which could be exploited further and future pharmaceutical, therapeutic efficiency and food preservation and applications.

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Effects of Artemisia annua methanolic extract on the enzymatic components of intermediary metabolism and the antioxidant system of Pseudococcus viburni Signoret

63%

Ramzi S. , Seraji A. , Gonbad R. A. , Mirhaghparast K. , Mojib-Haghghadam Z.

Journal of Plant Protection Research

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2018

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tom 58

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nr 3

EN

Toxicity and physiological alterations were determined in Pseudococcus viburni nymphs treated with Artemisia annua methanolic extract. The leaf dipping bioassay showed LC50 values of 0.287% and 0.194% 24 and 48 hours post-exposure. Activities of general esterases were significantly higher in the control nymphs than in those which had been treated except for the 48 h time interval using α-naphtyl acetate. The activity of glutathione S-transferase using CDNB (1-chloro-2,4-dinitrobenzene) in the control nymphs, was significantly higher than in the control at both time intervals while no significant difference was observed after 24 h in addition to the higher enzymatic activity in the treated nymphs after 48 h. All three aminotransferases were significantly more active in the control nymphs except for time intervals of 24 h for γ-glutamyl transferase and 48 h for alanine aminotransferase. Higher activities of lactate dehydrogenase, acid- and alkaline phosphatase were found in the control nymphs than in treated nymphs for all time intervals. Activities of the enzymes involved in the antioxidant system including catalase, peroxidase, superoxide dismutase, ascorbate peroxidase and glucose-6-phosphate dehydrogenase was increased in the treated nymphs compared to the control. Results of the current study demonstrated toxic effects of A. annua methanolic extract on P. viburni nymphs causing mortality and physiological turbulences.

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Chamomile methanolic extract mitigates small bowel inflammation and ROS overload related to the intestinal nematodes infection in mice

63%

Hajaji S. , Jabri M.-A. , Alimi D. , Rekik M. , Akkari H.

Acta Parasitologica

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2019

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tom 64

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nr 1

11

Antimycotic activity of low polar petroleum ether and interpolar methanolic young leaf extracts of Solanum nigrum L.

63%

Shivakumar Singh P. , Vidyasagar G. M.

International Letters of Natural Sciences

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2015

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tom 04

EN

Antimycotic activity of Petroleum ether and 98% methanolic young leaf soxhlet extract of Solanum nigrum (Solanaceae) was evaluated against dermatophytic fungi namely, Trichophyton rubrum, Trichophyton tonsurans, Trichophyton mentagrophytes, Microsporium gypseum, Candida albicans, and bacteria like, Staphylococcus aureus, Psudomonas aeruginosa, Bacillus subtilis, Escherichia coli. The maximum activity was observed in interpolar methanolic extract when compared to low polar petroleum ether extract. The minimum inhibitory concentration, minimum fungicidal concentration and minimum bactericidal concentration were determined against all the test strains. This study provides a basis for the isolation and purification of anti-dermatophytic compounds from the young leaves of S. nigrum.

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The central analgesic and anti-inflammatory activities of the methanolic extract of Carthamus oxycantha

63%

Bukhari I. A.

Journal of Physiology and Pharmacology

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2013

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tom 64

|

nr 3

13

Amoebicidal and amoebistatic effects of Artemisia argyi methanolic extracts on Acanthamoeba castellanii trophozoites and cysts

63%

Koloren O. , Koloren Z. , Sekeroglu Z. A. , Colayvaz M. , Karanis P.

Acta Parasitologica

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2019

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tom 64

|

nr 1

14

Preliminary study on the impact of methanolic extract of Elephantopus scaber Linn. on hair growth promoting effect in rats

63%

Sahoo H. B. , Sagar R. , Bhattamisra S. K. , Bhaiji A.

Herba Polonica

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2013

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tom 59

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nr 2

EN

Methanolic extract of Elephantopus scaber leaves was investigated for its role in hair growth in experimental rats. The 2% and 5% solution of prepared formulation using methanolic extract was studied for hair growth on wistar rats for 30 days. Minoxidil (2% solution) was taken as a reference standard. The prepared hair oil formulation of methanolic extract significantly (p<0.01) potentiated the hair growth initiation and completion time with dosedependent improvement in skin biopsy, hair length and hair weight. In vitro hair follicles development study showed the significant (p<0.05) improvement in the initiation of new hair follicles. Above mentioned results indicated that the methanolic extract of E. scaber rendered significant hair growth promotive effect.

PL

Badano wpływ wyciągu metanolowego z liści Elephantopus scaber na wzrost włosów u szczurów laboratoryjnych. Przez 30 dni badano wzrost włosów u szczurów Wistar po podaniu 2% i 5% preparatu sporządzonego z użyciem ekstraktu metanolowego. Substancją kontrolną był minoksidil (roztwór 2 %). Preparat z ekstraktu metanolowego przygotowany na bazie oleju istotnie (p<0,01) zwiększał inicjację wzrostu włosów i przyspieszał jego zakończenie. Podczas biopsji odnotowano też zależną od dawki poprawę stanu skóry, długości włosów i zwiększenie masy włosów. Podczas badaniu in vitro wykazano istotną (p<0,05) poprawę tworzenia się nowych mieszków włosowych. Powyższe wyniki wskazują, że wyciąg metanolowy z E. scaber może istotnie zwiększać porost włosów.

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Bronchodilator, vasolidator and spasmolytic activities of methanolic extract of Myrthus communis L.

63%

Janbaz K. H. , Nisa M. , Saqib F. , Imran I. , Zia-Ul-Haq M. , De Feo V.

Journal of Physiology and Pharmacology

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2013

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tom 64

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nr 4

16

Antioxidative properties of methanolic extracts from some Euonymus L. species

63%

Zbikowska B. , Sroka Z. , Rzadkowska-Bodalska H. , Wisnicka R.

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1996

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tom 44

|

nr 1-2

17

Evaluation of antiepileptic activity of methanolic leaves extract of Tragia involucrata Linn. in mice

51%

Varma G. G. , Mathai B. K. , Das K. , Gowda G. , Rammohan S. , Einstein J. W.

International Letters of Natural Sciences

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2014

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tom 12

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nr 2

EN

The present investigation was aimed to study an antiepileptic activity of methanolic extract of Tragia involucrata Linn in mice. In vivo screening models like maximal electroshock-induced convulsion (MES), pentylenetetrazole (PTZ) and picrotoxin (PTX) induced models are used to evaluate the antiepileptic effects of the extracts. The biochemical estimation was done by measuring the lipid peroxidation and reduced glutathione (GSH). In the MES induced convulsion, methanolic extract of Tragia involucrata (METI) at high dose (800 mg/kg body weight), showed high significant inhibition on tonic hind limb extension (THLE, 6.83 ±0.30***) and decrease in duration of stupor period (108.7 ±6.53***). In PTZ and PTX induced model METI (400 mg/kg and 800 mg/kg) showed significant delay on the onset of convulsions, decreased duration of convulsion and reduced mortality significantly. It also showed significant decrease in brain MDA level in lipid peroxidation profile, and increase in the brain glutathione levels in mice against PTZ induced convulsion. The results confirmed that Tragia involucrata Linn possesses dose dependent antiepileptic activity.

18

Effect of Artemisia annua L. on deterrence and nutritional efficiency of lesser mulberry pyralid (Glyphodes pylolais Walker) (Lepidoptera: Pyralidae)

51%

Khosravi R. , Sendi J. J. , Ghadamyari M.

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tom 50

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nr 4

EN

Methanolic extract of Artemisia annua L. were evaluated on growth and nutritional efficiency of lesser mulberry pyralid Glyphodes pyloalis (Lepidoptera: Pyralidae) in laboratory conditions (24±1°C, 75±5% RH and 16 L : 8 D). Feeding deterrence index was evaluated by a choice test method on < 24 h fifth instar larvae with 5, 2.5, 1.25 and 0.625 percent of the extract. The result indicated that increasing the concentration resulted in higher deterrence. The extract retarded larval growth significantly (EC50 = 3.63%) and also showed significant effects on the relative growth rate (RGR), efficiency of conversion of ingested food (ECI), efficiency of conversion of digested food (ECD), approximate digestibility (AD) and consumption index (CI). Lipid, protein and carbohydrate in treated insects were significantly reduced compared to the controls. Hence, methanol extract of A. annua could be considered as a strong deterrent which also affects the biochemical metabolism of the target pest. Methanol extract of A. annua has the potential for development as a botanical insecticide.

PL

Oceniano działanie wyciągu metanolowego Artemisia annua L. na wzrost i wydajność żywieniową zadarliby morwowej Glyphodes pylolais (Lepidoptera: Pyralidae) w warunkach laboratoryjnych (24±1°C, 75±5% wilgotności względnej fotoperiod – 16 godz. Światła i 8 godz. ciemności). Wskaźnik odstraszania żywieniowego, określano wybraną metodą na piątym pokoleniu larw przy wykorzystaniu wyciągu o stężeniu 5.25, 1.25 i o.625%. Wyniki wykazały, że wzrost stężenia powodował większe odstraszanie (DC50 = 0.48%). Wyciąg istotnie opóźniał wzrost larw (EC50 = 3.63%) i także wykazywał istotne działanie na względne tempo wzrostu (RGR), wydajność konwersji pobranego pokarmu (ECI), przybliżoną strawność (AD) i wskaźnik konsumpcji (IC). Tłuszcz, białko i węglowodany w traktowanych owadach były znacznie zredukowane w porównaniu do kontroli. Więc wyciąg metanolowy A. annua mógłby być uznany za silny związek odstraszający, wpływający także na metabolizm biochemiczny docelowego szkodnika. Wyciąg metanolowy A. annua ma potencjał stania się insektycydem botanicznym.

19

Chromatographic and spectrophotometric analyses of the DPPH free radical scavenging activity of the fractionated extracts from Lamium album L., Lamium purpureum L. and Viscum album L.

51%

Budzianowski J. , Budzianowska A.

Herba Polonica

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2006

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tom 52

|

nr 1-2

EN

Chloroform, butanolic and water fractions from the methanolic extracts of Lamium album L. and L. purpureum L. flowers and different organs of mistletoe (Viscum album L.), namely leaves, stalks and fruits were investigated for the free radical scavenging properties by using colour free radical DPPH • as a stain reagent for dot-blot assay on a T LC plate and two-dimensional thin-layer chromatography (2D-TLC) analysis (2D-TLC-DPPH test) as well as a dye reagent for the spectrophotometric assay. For each plant material, butanolic fractions showed the strongest activity, of which those of the Lamium species were nearly equal to that of the known antioxidant - BHA. According to 2D-TLC chromatography, the phenolic compounds present were responsible for the antiradical activity of the fractions.

PL

Frakcje chloroformowe, butanolowe i wodne ekstraktów metanolowych z kwiatów Lamium album L. i Lamium purpureum L. oraz różnych organów Viscum album L. (liście, łodygi, owoce) badano pod względem właściwości zmiatania wolnych rodników, stosując barwny wolny rodnik DPPH • jako odczynnik do testów plamowych na płytkach TLC, analizy metodą dwukierunkowej chromatografii cienkowarstwowej (2D-TLC) oraz oznaczeń spektrofotometrycznych. W wypadku każdego materiału roślinnego najsilniejszą aktywność wykazały frakcje butanolowe, z gatunków Lamium prawie równą aktywności znanego antyoksydantu – BHA. Z rezultatów chromatografii cienkowarstwowej dwukierunkowej 2DTLC wynika, że za aktywność przeciwrodnikową frakcji odpowiedzialne są obecne w nich związki fenolowe.

20

Effect of heating on antioxidative activity of rapeseed and evening primrose extracts

51%

Zadernowski R. , Nowak-Polakowska H. , Konopka I.

Polish Journal of Food and Nutrition Sciences

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1996

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tom 05

|

nr 2

EN

The composition and effect of heating (60°-110°C) on antioxidative activity in plant oil of rapeseed (RE) and evening primrose (EPE) methanolic extracts were studied. Different phenolics characterized the extracts. The EPE contained about 10-fold higher amount of phenolics (862.2 g/kg extract) than RE; flavanols (683.8 g/kg) and proanthocyanidins (760.1 g/kg) prevailed in the former and phenolic acid derivatives in the latter. The phenolic compounds of both extracts differed with the fenolic acids composition. Sinapic acid prevailed in rapeseed phenolics and protocatechic and gentisic acids in evening primrose phenolics. Both extracts had generally similar antioxidative activity in the temperature ranging from 60°C to 80°C with the oil peroxide values from 3.5 mmol O/kg to 5.0 mmol O/kg compared to the range of 6.0-7.0 mmol O/kg in control oils. The temperatures above 80°C decreased the antioxidative activity of both extracts and even made them to be prooxidative.

PL

Badano skład i wpływ temperatury (60-110°C) na właściwości przeciwutleniające ekstraktów metanolowych nasion rzepaku i wiesiołka. Stwierdzono, że olej tych nasion zawierał tokoferole, głównie α- i y-, w ilości 0,65 g/kg (rzepak) i 0,45 g/kg (wiesiołek) (tab. 1), a ekstrakty metanolowe nasion charakteryzowały się różnymi formami związków fenolowych. W porównaniu z ekstraktem rzepakowym, ekstrakt wiesiołka zawierał około 10-krotnie więcej związków fenolowych, wśród których dominowały flawanole i proantocyjanidyny (tab. 2). Kwasy fenolowe i ich pochodne dominowały w ekstrakcie rzepakowym. Związki fenolowe ekstraktów różniły się składem kwasów fenolowych (rys. 1). Ekstrakty metanolowe obu nasion wykazywały się generalnie taką samą aktywnością przeciwutleniającą (rys. 2). W temperaturze powyżej 80°C aktywność przeciwutleniająca ekstraktów zanikała lub nawet obserwowano przyśpieszenie procesu utleniania oleju roślinnego.