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  1. 7 Journal of Physiology and Pharmacology
  2. 2 Acta Academiae Agriculturae ac Technicae Olstenensis. Technologia Alimentorum
  3. 2 Acta Scientiarum Polonorum. Biotechnologia
  4. 1 Acta Biochimica Polonica
  5. 1 Animal Science Papers and Reports
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  1. 1 2020
  2. 3 2019
  3. 3 2017
  4. 1 2014
  5. 1 2013
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  1. 3 Chrzanowska J.
  2. 3 Gorski J.
  3. 3 Polomska X.
  4. 3 Szoltysik M.
  5. 3 Wojtatowicz M.
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1
Content available Research Study of the Conditions of Wastes Lipolysis Lipid Fraction
100%
Sklyar V. , Krussir G. , Lebedenko T. , Khomich G. , Kovalenko I.
Journal of Ecological Engineering
|
2019
|
tom Vol. 20, nr 3
152--156
EN
Biotechnological processing of secondary raw material resources of the oil and fat industry in useful products is the most expedient and effective in terms of both economic and environmental requirements. The obtained experimental results of the study indicate the prospect of lipolysis with the lipase Rhizopus japonicus fat fraction of waste generated during the hydrogenation of vegetable oils. The greatest activity in relation to olive oil is expressed by lipase Rhizopus oryzae. Lipase Rhizopus japonicus exhibits the highest activity relative to hydrogenated fat, which is explained by its substrate specificity. It was found that the content of free fatty acids in the hydrolyzate reached the saturation level after 72 hours of hydrolysis, and the concentration of triglycerides during this time of hydrolysis decreased to a minimum value. The results of research should be used to improve the processing technology of waste oil and fat industry in the food industry.
2
Content available Acute tadalafil administration increases plasma fatty acids without changes in the inflammatory response in healthy men
100%
Ceci R. , Duranti G. , Sgrò P. , Sabatini S. , Di Luigi L.
Acta Biochimica Polonica
|
2017
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tom 64
|
nr 4
687-691
EN
Purpose: Tadalafil, the phosphodiesterase type 5 inhibitor (PDE5I), has been shown to reduce visceral adipose tissue in rabbit and to improve lean mass content in non-obese men. In order to clarify this effect in humans, in the present study we determined the impact of an acute oral tadalafil administration on lipolysis by evaluating plasma free fatty acids (FFAs) and glycerol. FFAs are potential modulator of inflammation response that we evaluated through tumor necrosis factor alpha (TNFα), interleukin 6 (IL6), interleukin 8 (IL8) and interleukin 10 (IL10) plasma levels. Moreover, we determined whether the effects of tadalafil would be reflected in variation of plasma levels of cGMP and NO, two important molecules involved in PDE5Is signaling. Methods: Twelve healthy subjects were supplemented with 20 mg of tadalafil or a placebo, in a double-blind, randomized, cross-over design. Blood samples were collected immediately before, and at 2, 6, and 24 hours post ingestion, and assayed for biochemical analysis. Results: A condition effect was noted for FFAs and glycerol, with values higher for tadalafil when compared to the placebo group, at 2 and 6 hours post ingestion. No statistically significant effects were noted for glucose, cGMP, nitrate and nitrite. No inflammatory response was induced by tadalafil. Conclusion: Tadalafil, in human subjects, increases lipolysis as evidenced by a significant increase in circulating FFAs and glycerol, without affecting the plasma cGMP and NO levels; noticeably, the increase in FFAs did not develop an inflammatory response. Further well-controlled studies are warranted to assess the impact of tadalafil administration on weight/fat loss.
3
Content available Biochemical and microbiological changes in cheese inoculated with Yarrowia lipolytica yeast
86%
Szoltysik M. , Dabrowska A. , Babij K. , Pokora M. , Zambrowicz A. , Polomska X. , Wojtatowicz M. , Chrzanowska J.
Żywność Nauka Technologia Jakość
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2013
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tom 20
|
nr 4
EN
A Yarrowia lipolytica JII1c yeast strain, isolated from the Polish ‘Rokpol’ mould cheese, was used as an adjunct culture in the production of a Dutch-type cheese. Its effect on the microbiological and biochemical characteristics of the cheese was evaluated in this research study. Milk used to produce the cheese was inoculated with 105 cfu/mL yeast cells. During the ripening process, the yeast population grew systematically to reach a maximum level of 7.9 log cfu/g in the sixth week of maturation, whereas the number of lactic acid bacteria increased until the fourth week of ripening. Thereafter, the number of microorganisms in the both groups decreased. After 8 weeks of ripening, the pH value of cheese inoculated with yeasts was significantly higher than that of the control cheese sample (produced without those microorganisms) and reached the levels of 6.37 and 5.47, respectively. In the experimental cheeses, it was also found that the utilization rate of lactic and citric acids was higher. Additionally, the concentration levels of water-soluble nitrogen (WSN) and free amino groups (FAG) in the experimental cheeses were about twice as high as in the control cheese sample. A more intensive proteolysis in the experimental cheese was accompanied by a higher accumulation of biogenic amines, especially of tyramine, putrescine, and 2-phenylethylamine; in the experimental cheese, after 8 weeks, their contents amounted to: 167.01, 77.90, and 69.54 mg/100 g, respectively. In contrast, the concentration of histamine was similar in both cheeses (9.47 and 9.81 mg/100 g in the control and experimental cheese samples, respectively). Also, the experimental cheese revealed more pronounced lipolysis resulting in a higher accumulation of free fatty acids, especially of butyric, myristic, palmitic, stearic, and oleic acids. It can be concluded that the Y. lipolytica JII1c grew well in the cheese causing the ripening process of the cheese to significantly accelerate.
PL
Szczep drożdży Yarrowia lipolytica JII1c wyizolowany z sera Rokpol z przerostem pleśni zastosowany został jako kultura wspomagająca do produkcji sera typu holenderskiego. W pracy oceniano jego wpływ na właściwości biochemiczne wyprodukowanego sera oraz na rozwój mikroflory. Mleko użyte do produkcji sera zostało zaszczepione komórkami drożdży w ilości 105 jtk/mL. Podczas dojrzewania liczba drożdży systematycznie wzrastała, osiągając w szóstym tygodniu dojrzewania poziom maksymalny 7,9 log jtk/g, natomiast liczba bakterii mlekowych wzrastała jedynie do czwartego tygodnia dojrzewania. W kolejnych tygodniach dojrzewania liczba obu grup drobnoustrojów stopniowo malała. Po 8 tygodniach dojrzewania pH sera, do którego wprowadzono drożdże, było znacząco wyższe w porównaniu z serami kontrolnymi wyprodukowanymi bez udziału tych mikroorganizmów i osiągnęło wartość odpowiednio 6,37 i 5,47. W doświadczalnych serach obserwowano także intensywniejsze przemiany kwasu mlekowego i cytrynowego, a oznaczone wartości azotu rozpuszczalnego (WSN) i wolnych grup aminowych (FAG) były około 2-krotnie wyższe. Intensywniejszej proteolizie w serach otrzymanych przy udziale drożdży Yarrowia lipolytica towarzyszyła także wyższa zawartość amin biogennych, zwłaszcza tyraminy, putrescyny i 2-fenyloetylaminy. Ich ilości, w przeliczeniu na 100 g sera, wynosiły w 8. tygodniu dojrzewania odpowiednio 167,01, 77,90 i 69,54 mg. Stężenie histaminy w serach badanych i kontrolnych było zbliżone i wynosiło 9,81 i 9,47 mg w 100 g sera. Intensywniejszą lipolizę odnotowano w serach eksperymentalnych, co spowodowało większe stężenie wolnych kwasów tłuszczowych, zwłaszcza masłowego, mirystynowego, palmitynowego, stearynowego i oleinowego. Wykazano, że szczep drożdży Y. lipolytica JII1c wprowadzony do sera wpływał na przyspieszenie procesu jego dojrzewania.
4
Qualitative changes observed in cream powder during storage
86%
Szpendowski J. , Juskiewicz M. , Panfil-Kuncewicz H. , Wilczewska J.
Natural Sciences
|
2001
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tom 08
163-174
5
Content available remote Effect of acute exercise on mRNA and protein expression of main components of the lipolytic complex in different skeletal muscle types in the rat
72%
Miklosz A. , Baranowski M. , Lukaszuk B. , Zabielski P. , Chabowski A. , Gorski J.
Journal of Physiology and Pharmacology
|
2019
|
tom 70
|
nr 3
6
Content available remote Effect of ostarine (enobosarm/GTx024), a selective androgen receptor modulator, on adipocyte metabolism in Wistar rats
72%
Leciejewska N. , Pruszynska-Oszmalek E. , Bien J. , Nogowski L. , Kolodziejski P. A.
Journal of Physiology and Pharmacology
|
2019
|
tom 70
|
nr 4
7
A relationship between somatic cell count, polymorphic form of beta4-defensin and susceptibility of cow milk fat to lipolysis
72%
Strzalkowska N. , Jozwik A. , Polawska E. , Zdanowska-Sasiadek Z. , Bagnicka E. , Pyzel B. , Lipinska P. , Horbanczuk J. O.
Animal Science Papers and Reports
|
2014
|
tom 32
|
nr 4
EN
The aim of this study was to evaluate the effects of somatic cell count and the polymorphic form of β4-defensin on the concentration of free fatty acids (FFA) and physico-chemical characteristics of cow’s milk. The study was carried out on 120 Polish Holstein-Friesian Black and White dairy cows.The animals were maintained in a loose barn and fed with the TMR system according to the INRA norm. The animals were divided into groups according to their polymorphic form of the defensin β4 gene: 1st – CT (def-1); 2nd – CC (def-2) and into two groups in terms of their somatic cell count:1st - <3×105 (SCC-1) and 2nd – 3×105 – 6×105 (SCC-2) cell/ml. Milk samples were collected once a month during the whole lactation. Chemical composition and some physico-chemical parameters of milk were determined by automated infrared analysis with a Milkoscan FT2 instrument. SCC were evaluated using BactoCaunt IBCm. A relationship was found between polymorphic forms of the defensin gene and the level of FFA in milk directly after milking (CT
8
Content available remote The skeletal and heart muscle triacylglycerol lipolysis revisited
72%
Knapp M. , Gorski J.
Journal of Physiology and Pharmacology
|
2017
|
tom 68
|
nr 1
9
Content available remote The metabolic suppressor 3-iodothyronamine enhances lipolysis in 3T3-L1 adipocytes via activation of the adenosine monophosphate-activated protein kinase/forkhead box O1 signaling pathway
72%
Kim M. , Park K. , Choi I.
Journal of Physiology and Pharmacology
|
2020
|
tom 71
|
nr 3
10
Content available remote Studies of phosphodiesterase effects on adipose tissue metabolism in obese subjects by the microdialysis technique
72%
Flechtner-Mors M. , Jenkinson C. P. , Alt A. , Biesalski H. K. , Adler G. , Ditschuneit H. H.
Journal of Physiology and Pharmacology
|
2005
|
tom 56
|
nr 3
EN
The effect of non-selective (theophylline) inhibition of cyclic AMP breakdown on norepinephrine stimulated lipolysis rate was investigated in subcutaneous adipose tissue of obese subjects. In addition, changes in interstitial glucose and lactate concentration were assessed by means of the microdialysis technique. The interaction of endogenous released insulin and theophylline on adipocyte metabolism was determined. Theophylline and norepinephrine alone increased glycerol outflow significantly. When both agents were perfused in combination, interstitial glycerol concentration increased further. The enhanced glycerol level due to theophylline application was slightly decreased by insulin. In the presence of theophylline, extracellular glucose concentration increased, in contrast to the catecholamine. Norepinephrine decreased interstitial glucose level. When both drugs were added in combination, the level of interstitial glucose increased to about 1 mM, greater than with theophylline alone. With each intervention, lactate was synthesized. Local adipose tissue blood flow was increased by theophylline and theophylline plus norepinephrine. In conclusion, post-receptor mechanisms increased norepinephrine maximal stimulated lipolysis rate in subcutaneous adipose tissue. Glucose uptake was inhibited by the non-specific inhibitor of phosphodiesterase. The effect of insulin on inhibition of lipolysis was modest but sustained in the presence of high theophylline (10-4 M) concentration. Phosphodiesterase activity may be relatively low in obese subjects in comparison with lean subjects. In lean subjects theophylline caused a transient reversal of the antilipolytic effect of insulin.
11
Wzrost drozdzy w modelowym serze i ich wplyw na degradacje bialek i tluszczu
58%
Czajgucka A. , Chrzanowska J. , Juszczyk P. , Szoltysik M. , Polomska X. , Wojtatowicz M.
Acta Scientiarum Polonorum. Biotechnologia
|
2006
|
tom 05
|
nr 1-2
95-103
12
Content available remote Effect of tachycardia on mRNA and protein expression of the principal components of the lipolytic system in the rat's heart ventricles
58%
Wojcik B. , Miklosz A. , Zabielski P. , Chabowski A. , Gorski J.
Journal of Physiology and Pharmacology
|
2017
|
tom 68
|
nr 5
13
Content available Effect of hypothermia on the insulin - receptor interaction in adipose plasma membranes
58%
Torlinska T. , Mackowiak P. , Nogowski L. , Kozlik J.
Journal of Physiology and Pharmacology
|
1995
|
tom 46
|
nr 3
14
Content available remote Crossroads of cytokine signalling - the chase to stop muscle cachexia
51%
Pajak B. , Orzechowska S. , Pijet B. , Pijet M. , Pogorzelska A. , Gajkowska B. , Orzechowski A.
|
|
tom 59
|
nr 9
251-264
15
Zastosowanie mikrobiologicznego preparatu przyspieszajacego dojrzewanie sera w produkcji serwitu tylzyckiego. Czesc 2. Wplyw zroznicowanego dodatku zakwasu
44%
Jarmul I. , Reps A. , Tomasik J.
Acta Academiae Agriculturae ac Technicae Olstenensis. Technologia Alimentorum
|
1998
|
tom 30
35-44
16
Zastosowanie mikrobiologicznego preparatu przyspieszajacego dojrzewanie sera w produkcji serwitu tylzyckiego. Czesc 3. Optymalny etap dodania preparatu
44%
Jarmul I. , Reps A. , Tomasik J.
Acta Academiae Agriculturae ac Technicae Olstenensis. Technologia Alimentorum
|
1998
|
tom 30
45-57
17
Wzrost i enzymatyczna aktywność drożdży w mleku różnych gatunków przeżuwaczy
44%
Szoltysik M. , Zelazko M. , Polomska X. , Wojtatowicz M. , Chrzanowska J.
Acta Scientiarum Polonorum. Biotechnologia
|
2008
|
tom 07
|
nr 2
18
Circadian variations of serum thyrotropin, thyroxine, triiodothyronine, reverse triiodothyronine, corticosterone and lipids in starved rats
44%
Zwirska-Korczala K. , Ostrowska Z. , Kucharzewski M. , Marek B. , Kos-Kudla B. , Buntner B. , Swietochowska E.
Bulletin of the Polish Academy of Sciences. Biological Sciences
|
1993
|
tom 41
|
nr 4
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