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Content available remote Excitatory and inhibitory effects of transcranial magnetic stimulation
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EN
This paper reviews the use of transcranial magnetic stimulation (TMS) in investigating intracortical circuits in the primary motor cortex (MI). TMS is a noninvasive and painless method of stimulating the human brain and has become a widely used technique in neuro-physiology and neurology. When TMS is applied to the M1, it generates a motor evoked potential (MEP) in the target muscles. TMS also activates different intracortical circuits within the M1 and connections from other cortical areas to the M1. These intracortical circuits interact with each other. Abnormalities in these circuits are found in neurological and psychiatric disorders and studies of these circuits are useful in understanding the pathophysiology of these conditions.
EN
A smart grid is a kind of energy cyber-physical system (ECPS) with the interdependency of information and physicality. A cyber-attack gravely threatens the safe and stable operation of a physical power grid. Cyber-security reinforcement of smart grid has become a research issue. However, the information network scale of a smart grid is massive, and the generation of security reinforcement strategies has become a problem. Therefore, a generation method of security reinforcement strategies based on an attribute-based attack graph was proposed in this study. The method defined a smart grid based on premise and consequence attributes to form an attribute-based attack graph. With this graph, the method for the generation of security reinforcement strategies was transferred to the minimum dominating set of the attribute-based attack graph and solved to realize space reduction in the security reinforcement strategies. An algorithm for the generation of security reinforcement strategies was designed based on the greedy algorithm, and strategies for large-scale cyber security reinforcement of the smart grid were determined to eliminate the complexity and difficulty of this problem effectively. Through a simulation analysis of a large-scale node network, the efficiency of the generation method of reinforcement strategies based on the attribute based attack graph and minimum dominating set was verified. Results show that the proposed method can be used for security reinforcement of large-scale complicated networks of a smart grid.
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EN
Novel pH-sensitive hydrogels were prepared through crosslinking of poly(.gamma.-glutamic) acid (.gamma.-PGA) by using 1,4-butanediol diglycidyl ether as a cross-linker, tetraethylammonium bromide as a catalyst, and reacting in DMSO. The dependence of the swelling ratio of the hydrogels on pH values, ionic strength and cross-linking degree was investigated. It was found that the pH-sensitive range was clearly extended through introducing multiple hydrogen bonds to the hydrogel network during the preparation. The swelling ratios of ?-PGA hydrogels increased with the increase in pH of the aqueous solution from 2 to 9. The swelling of the .gamma.-PGA hydrogels was firstly controlled by the ionization of carboxyl groups in the hydrogels within the pH range from 2 to 5, and then controlled by breaking of the multiple hydrogen bonds in the hydrogels within the pH range from 5 to 9. The swelling ratios of .gamma.-PGA hydrogels were also strongly dependent on the ionic strength of the medium and cross-linking degree of the hydrogels. Increasing the ionic strength and the crosslinking degree resulted in a decrease in the swelling ratio of the hydrogels.
EN
Auxin has been widely implicated in various aspects of plant growth and development, including flower development. In order to further elucidate the role of auxin during flower development, especially on the pistil development process, auxin response factors (ARFs), an important component in auxin signalling pathway, were studied in the early flower buds of Japanese apricot (Prunus mume Sieb. et Zucc). In this study, a comprehensive overview of the ARF gene family in Japanese apricot is presented, including the chromosomal locations, phylogenetic relationships, gene structures, the domain and nuclear localization analysis. Seventeen Japanese apricot genes that encode ARF proteins (PmARFs) have been identified based on the genome sequence of Japanese apricot. Comparison of the expression of some PmARF genes between perfect and imperfect flower buds in Japanese apricot suggests that PmARFs, especially the PmARF13 and PmARF17 gene may be required for pistil development and function in Japanese apricot. These results will be useful for future functional analyses of the ARF family genes in plants.
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