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1
Content available remote Pomiary sygnałów przewodzonych przez włókna nerwowe
Paśniczek R., Wildner K.
Przegląd Elektrotechniczny
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2010
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R. 86, nr 12
354-356
PL
W niniejszej pracy przedstawiono stanowisko do badań elektrod typu „cuff” (zewnątrz-nerwowych), oraz uzyskane za jego pomocą wyniki pomiarów charakterystyk przenoszenia elektrod. Zaprezentowano również wyniki badań symulacyjnych wielkości sygnałów, które mogłyby być odbierane za ich pomocą z pojedynczego włókna nerwowego, oraz zdolność tłumienia zakłóceń zewnętrznych.
EN
This work aims at describing a research laboratory for studies on „cuff” type of electrodes and results obtained from measurements of transfer functions have been presented. The work includes results from simulation examinations of signal quantities which might be received from a single nerve fibre. Also capability of examined electrodes to reject external noises was determined.
2
Content available Mobilny system do pomiaru wyładowań niezupełnych sterowany falami elektroencefalograficznymi
Błachowicz A., Paszkiel S.
Pomiary Automatyka Robotyka
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2010
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R. 14, nr 2
12-16
PL
W artykule przedstawiono koncepcję sterowanego falami mózgowymi, mobilnego systemu do pomiaru wyładowań niezupełnych. Do wykonywania pomiarów wyładowań niezupełnych w dielektrykach urządzeń elektrycznych (kondensatory, transformatory) został opracowany specjalny robot. Ponadto przedstawiona została idea sprzęgnięcia robota z mózgiem człowieka zapewniającego bezpośrednią komunikację na linii: mózg człowieka-robot.
EN
The article presents the concepts of a mobile system for measurements of partial discharges controlled by brain waves. In order to describe that, a robot, which takes measurements of partial discharges, has been worked out. The discharges may occur in a isolator of electrical devices such as capacitors and transformers. What is more, a concept of a link between the robot and a human brain is described, in order to ensure a direct communication on the level of the human brain and the robot.
3
Content available remote In memoriam of Prof. M. Nałęcz
Wójcicki J. M., Weryński A.
Biocybernetics and Biomedical Engineering
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2009
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Vol. 29, no. 2
5-8
EN
On February 6, 2009 Professor Maciej Nałęcz the Editor-in-Chief of the journal of Biocybernetics and Biomedical Engineering passed away suddenly. He was a pioneer in the field of biomedical engineering, a leader who had made a real progress in this discipline.
4
Content available remote Analysis of effect of radiation exposure on cultured cells using electrical cell-substrate impedance Sensing (ECIS) method
Goda N., Yamamoto Y., Nakamura M., Maruyama T., Kusuhara T., Mohri S., Kataoka N., Kajiya F.
Biocybernetics and Biomedical Engineering
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2007
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Vol. 27, no. 1-2
227-236
EN
A mathematical model for the micro-dynamics of cultured cells measured with the ECIS (Electrical Cell-substrate Impedance Sensing) system that can separately evaluate the cell-to-cell distance and the cell-to-substrate distance is proposed. For wide applications of this method, mathematical models considering various types of cells and confluent conditions were constructed. Using ECIS TM, frequency the characteristics of 25 Hz to 60 kHz of impedance of HUVEC (human umbilical vein endothelial cells), BAEC (bovine aortic endothelial cells), in the pre-confluent condition and the full confluent condition of each cell were measured. A mathematical model of the micro-dynamics of the cultured cells measured with ECIS from 1 kHz to 10 kHz, which was the most interesting frequency range for the micro-dynamic analysis in the ECIS methods is proposed. The evaluation method of the cell-to-cell distance (A) and the cell-to-substrate distance (h) could be improved. In the application, we investigated the effect of the X-ray radiation exposure from 1 Gy to 100 Gy on the cultured cells BAEC using the ECIS system. Impedance changes could be confirmed by exposure to 100 Gy. The X-ray stimulation of 100 Gy resulted in a significant increase of the value of the cell-to-cell distance (A).
5
Content available remote 3D matrigel culture improves differentiated functions of HepG2 cells in vitro
Kinasiewicz J., Kawiak J., Weryński A.
Biocybernetics and Biomedical Engineering
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2006
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Vol. 26, no. 4
47-54
EN
In our study, the influence of culture conditions (monolayer and 3D Matrigel) of hepatocyte cell line (buman hepatoma cell line, HepG2) on their metabolic activity was assessed. Albumin synthesis by HepG2 cells was significantly higher in Matrigel culture as compared to monolayer culture of the cells. 3D culture improved urea production by HepG2 cells. The detoxification experiments revealed that HepG2 cells do not metabolize lidocaine neither in monolayer nor in 3D culture. 3D culture significantly improved cell polarity analyzed by F-actin staining and carboxyfluorescein excretion. In conclusion, the 3D Matrigel culture improves highly differentiated hepatic functions of HepG2 cells.
6
Content available remote Ranked designing of prognostic neural models for survival data
Bobrowski L., Krętowska M.
Biocybernetics and Biomedical Engineering
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2002
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Vol. 22, no. 2-3
223-239
EN
The procedure of designing the non-linear dependencies of survival time on a family of covariates is described in the paper. This dependence is treated as a prognostic model. The first stage of this procedure involves designing such layers of formal neurons which are ranked with respect to selected subsets of censored data. The model based on the hierarchical networks of formal neurons results in the piecewise constant dependence of the survival time on the covariates. The replacement of the formal neurons by the logistic ones made it possible transform this dependence into differentiable, regression-type function.
7
Content available remote Practical approaches to statistical pattern recognition
Jóźwik A.
Biocybernetics and Biomedical Engineering
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2002
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Vol. 22, no. 2-3
207-221
EN
The paper describes new approaches to statistical pattern recognition. All presented methods are based on a distance function. The properties of these methods and their usefulness are illustrated on real problems. Some tasks with small and very large training sets are described to shown an effectiveness of the proposed approaches. There is no one universal method that would be satisfactory for all object classification problems. That's why several methods have been demonstrated.
8
Content available remote Physical and mathematical model of human hip joint load
Włodarski J., Szmigiel A., Żołyński K., Kaczmarek J.
Biocybernetics and Biomedical Engineering
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2002
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Vol. 22, no. 1
95-102
EN
Analysing human gait cyclogram and reactions of the foundation, kinematics and dynamics of loads realised on a test stand were tried to be brought closer to real object. To reconstruct hip joint load diagram, basic loads resulting from physiology of movement were isolated. Physical model conditioned on gait cyclogram is designed to describe physical load of human hip joint and may be presented in the form of characteristic "double peak". Mathematical model of human hip joint load approximates with good accuracy time serious of five harmonics. This model has been adapted for the realisation of the design for a test stand - human hip joint simulator enabling to perform static and dynamic testing of an artificial hip joint.
9
Content available remote Multivariate Inference in clinical trials - tests with model choice, confidence regions
Läuter J., Kropf S.
Biocybernetics and Biomedical Engineering
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2002
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Vol. 22, no. 1
5-16
EN
In the paper, the formerly introduced spherical multivariate tests are coupled with procedures for selecting the relevant variables. These procedures work in such a way that a non-relevant set of variables is chosen with the probability of significance \alfa, at most. Furthermore, a new method of the calculation of linear principal-component scores is presented, which is based only on the within-sample covariances and yields, nevertheless, a level-\alfa test in each case. This method enables us to determine novel multivariate confidence regions of the unknown mean vector. The statistical procedures are demonstrated by a neurological example.
10
Content available remote Monitoring pilot's eye movements during the combat flight - the white box
Ober J. K., Ober J. J., Malawski M., Skibniewski W., Przedpelska-Ober E., Hryniewiecki J.
Biocybernetics and Biomedical Engineering
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2002
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Vol. 22, no. 2-3
241-264
EN
Modern fighter pilots are often exposed to excessive accelerations. The resulting brain hipoxia can lead to G-LOC (G-induced loss of consciousness). Authors discuses the effects of microcirculatory adaptation released by the push-pull condition (rapid change from minus to plus Gz). The memory effect of vaso-pull condition (rapid change from minus to plus Gz). The memory effect of vaso-constriction due to - Gz can be responsible for intermittent blocking of the compensatory vasodilatation and diminishing the +Gz tolerance of pilots tested on the centrifuge. Authors consider the push-pull condition to be analogous to the rapid blocking of the brain perfusion caused by the high plus Gz onset rates (1,G/s). Using the visual symptoms (narrowing of the visual field) is not longer adequate for monitoring the centrifuge push-pull trainig. Authors discuses the possibility of using the saccadic eye movements as being the most adequate physiological signal to monitor the pilot's consciousness. Measuring pilots eye movements requires to develop a miniature complex motion transducer which can be used during centrifuge training as well as during the flight (the White Box). Problems encountered during the system development are discussed.
11
Content available remote Lung mechanics measurement independent on ventilatory treatment
Darowski M., Kozarski M.
Biocybernetics and Biomedical Engineering
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2002
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Vol. 22, no. 4
115-121
EN
A new method of lungs mechanics calculation has been developed, which is independent on the method of ventilatory support and may be used automatically during long-term treatment. Lungs compliance assessment is based on the periodical measurements od airway pressure during expiration. Airways resistance is calculated from expiratory time constant. The results of preliminary, model studies showed that proposed method has a clinically acceptable accuracy and can be performed by a separate instrument, independent on a type of the respirator used.
12
Content available remote Linear visualising transformations and convex, picewicewise linear criterion functions
Bobrowski L., Topczewska M.
Biocybernetics and Biomedical Engineering
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2002
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Vol. 22, no. 1
69-78
EN
Designing the linear, separable transformations aimed at enhancing of differences between selected categories is described in the paper. The designing procedure is based on minimisation of the convex and piecewise-linear criterion functions defined on the learning data sets. The separable transformations could be used not only in exploratory data analysis and data mining but also in medical diagnosis support systems.
13
Content available remote Grade exploratory methods applied to some medical data sets
Pleszczyńska E., Szczesny W.
Biocybernetics and Biomedical Engineering
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2002
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Vol. 22, no. 1
17-30
EN
Two sets of medical categorical data are analyzed by means of grade exploratory methods, based on one fundamental procedure called the grade correspondence analysis (GCA). A special attention is put on visualization. The paper is a contribution to discussion concerning visualization of categorical data, which is going on in contemporary statistical literature.
14
Content available remote From pattern recognition to image interpretation
Kulikowski J. L.
Biocybernetics and Biomedical Engineering
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2002
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Vol. 22, no. 2-3
177-197
EN
In this paper selected problems concerning computer-aided image processing in biomedical applications are described. The problems are related to a multi-year activity in this domain of the Departament of Biomedical Information Processing Methods of the Institute of Biocybernetics and Biomedical Engineering PAS in Warsaw. In particular, an extension of the k-NN pattern recognition algorithm on the case of non-metric observation spaces is described. An example of a composite pattern recognition based on morphological parameters is presented. A concept of relations recognition as an extension of pattern recognition is also shortly described. In the last section some remarks concerning image interpretation methods have been given.
15
Content available remote Biography and scientific activity of prof. dr Maciej Nałęcz
Weryński A.
Biocybernetics and Biomedical Engineering
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2002
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Vol. 22, no. 2-3
7-68
16
Content available remote Automatic understanding of medical images - new achievements in syntactic analysis of selected medical images
Tadeusiewicz R., Ogiela M. R.
Biocybernetics and Biomedical Engineering
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2002
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Vol. 22, no. 4
17-29
EN
In the paper we try to solve very difficult problem connected with the advances in medical imaging technology: how to replace the goal of image recognition by image understanding. The problem under consideration is crucial one for all applications of information technology in automated systems devoted both for automatic medical diagnosis and successful searching in medical databases distributed troughout the world. The key problem analysis is how to model processes of image understanding by physician. We develop new tool for intelligent perception of differences between images of normal organs and pathological cases, instead of simple image recognition. We also presented how the same method can be used for searching of multimedial medical information in the respective databases. Such indexing approach enables an intelligent selection of interested case of illness based on visual queries.
17
Content available Kinetic analysis of LDL apoB transport and metabolism in non-steady states
Weryński A., Nahorski Z., Angelin B., Berglund L., Eriksson M.
Control and Cybernetics
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2000
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Vol. 29, no 1
405-425
EN
In this paper a novel kinetic analysis is used for evaluation of the low density lipoprotein (LDL) apoB fractional catabolic rate (FCR) after LDL apheresis which creates a nonsteady state. The formulae for calculation of FCR, and LDL rate of appearance (Ra) as functions of time have been derived. Calculations for one normal and one familial hypercholesterolemic (FH) subjects showed that FCR as well as Ra exhibited variations which can be attributed to the circadian rhythm in LDL metabolism. LDL apheresis had a little impact on both Ra and FCR in normal as well as in FH subjects. However, Ra in FH subject was found to be much higher than - that in the normal subject.
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