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Methods and measurements in radiation synovectomy with 90Y of knee joint dosimetry

Autorzy
Treść / Zawartość
Identyfikatory
Warianty tytułu
Konferencja
Proceedings of the 14th National Scientific Meeting of the Polish Radiation Society 24-26 Septemebr 2007, Kielce, Poland
Języki publikacji
EN
Abstrakty
EN
Radioisotope synovectomy is based upon an yttrium-90 colloid injected into the knee joint (the usual injected activity ranges from 111 MBq to 222 MBq per joint). Execution of the procedure needs participation of a nuclear medicine specialist as well as an orthopedist or a rheumatologist and a technologist who prepares radiopharmaceuticals. All of these participants are exposed to ionizing radiation. The ionization doses for patients and personnel are dependent not only on the activity injected, but also on the method and process of injection as well as the radioactivity measurement procedure used. In the experiments performed, a significant influence of the biodistribution of the radioisotopic substance on the exposure results has been observed.
Czasopismo
Rocznik
Strony
39--43
Opis fizyczny
Bibliogr. 14 poz., rys.
Twórcy
  • Department of Nuclear Medicine, Medical University of Gdańsk, 7 Dębinki Str., 80-211 Gdańsk, Poland, Tel.: +48 58 349 22 03, Fax: +48 58 349 22 00, mkempinska@amg.gda.pl
Bibliografia
  • 1. Badiavas K, Chatzopoulos D, Markou P (2006) Radiation doses from patients undergoing yttrium-90 silicate knee radiosynovectomy. Hell J Nucl Med 9:65–68
  • 2. Chuang J, Lo J (1996) Extraction chromatographic separation of carrier-free 90Y from 90Sr/90Y generator by crown ether coated silica gels. J Radioanal Nucl Chem 204:83–93
  • 3. Edmonds J, Smart R, Laurent R, Butler P (1994) A comparative study of the safety and efficacy of dysprosium-165 hydroxide macro-aggregate and yttrium-90 silicate colloid in radiation synovectomy – a multicentre double blind clinical trial. Br J Rheumatol 33:947–953
  • 4. Decree of the Council of Ministers from 18.01.2005 on the limits of ionizing doses (2006) Dziennik Ustaw, no. 20 item 168 (in Polish)
  • 5. Encyclopaedia of physics (1973) PWN, Warszawa (in Polish)
  • 6. Filipiak B, Mlicki K, Haratym Z (1999) Should internal risk of medical personnel be monitoring? Współcz Onkol 6:259–261 (in Polish)
  • 7. Franssesen M, Koenders E, Boerbooms A, Buijs W (1997) Does application of radiographic contrast medium in radiation synovectomy influence the stabillity of Yttrium-90 colloid? Br J Rheumatol 36:506–508 8. Garrean S, Espat J (2004) Yttrium-90 internal radiation
  • therapy for hepatic malignancy. Surg Oncol 14:179–193
  • 9. http://www.emea.eu.int/humandocs/PDFs/EPAR/zevalin/H-547-PI-pl.pdf (11.05.2005)
  • 10. Kennedy A, Nutting C, Coldwell D, Gaiser J, Drachenberg C (2004) Pathologic response and microdosimetry of 90Y microspheres in man: review of four explanted whole livers. Int J Radiat Oncol Biol Phys 60:1552–1563
  • 11. Leichner PK, Akabani G, Colcher D, Harrison KA (1997) Patient-specific dosimetry of Indium-111- and Yttrium-90-labeled monoclonal antibody CC49. J Nucl Med 38:512–516
  • 12. Szymański W (1996) Nuclear physics. Outline of problems of nuclear transformations. Wydawnictwo Naukowe PWN, Warszawa (in Polish)
  • 13. Vaňura P, Jedlinákova-Křižowa V, Vobecky M (2006) The use of liquid scintillation spectrometry for the determination of radionuclidic purity of 90Y from a radiochemical 90Y/90Sr generator. J Radioanal Nucl Chem 267:501–503
  • 14. Zanzonico B, Binkert B, Goldsmith S (1999) Bremsstrahlung radiation exposure from pure beta-ray emitters. J Nucl Med 40:1024–1028
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BUJ6-0023-0047
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