The influence of chronic supply of vanadium compounds on organ weights and body mass in animal diabetes model (NZO)

• Autorzy: Krośniak Mirosław , Szklarzewicz Janusz , Gryboś Ryszard , Tatar Barbara , Yildirim Metin , Sahin Bilge , Yuksek Nafize Didem , Ustundag Mustafa

Identyfikatory

DOI

10.5604/01.3001.0013.1563

• Języki publikacji: EN

Abstrakty

EN

Vanadium is an element that has an effect on improving glucose levels in animals with diabetes. However, its operation is strongly dependent on the chemical structure of compounds of this element. The influence of newly synthesized vanadium compounds on biochemical processes is also unknown. The paper presents the influence of eight new vanadium compounds on organ weights of animals (mice NZO) in whom diabetes was induced by a high-fat diet during 8 weeks. Tested vanadium complexes were administered by 5 weeks. After this time organs were collected and weighed. Tested complexes had a remarkable different effect on organ weights, despite having similar composition ([VO(L)(phen)] and the same co-ligand (1,10-phenanthroline) . This indicate on separate metabolic pathways of these compounds in the body of tested animals and role of the tridentate L Schiff base ligands. The compounds C2, C3 and C5 shoved biggest influence on organs weight and these results suggest influence on the metabolic pathways and therefore are interesting for further investigations.

Słowa kluczowe

EN

vanadium; organ weight; body mass; diabetes

PL

wanad; waga narządów; masa ciała; cukrzyca

• Wydawca: Państwowa Wyższa Szkoła Zawodowa w Tarnowie
• Czasopismo: Science, Technology and Innovation
• Rocznik: 2019
• Tom: Vol. 4, no. 1
• Strony: 63--73
• Opis fizyczny: Bibliogr. 28 poz., rys.

Twórcy

autor

Krośniak Mirosław

• Department of Food Chemistry and Nutrition, Medical College, Jagiellonian University, 30-688 Kraków, Medyczna 9

autor

Szklarzewicz Janusz

• Faculty of Chemistry, Jagiellonian University, 30-387 Kraków, Gronostajowa 2

autor

Gryboś Ryszard

• Faculty of Chemistry, Jagiellonian University, 30-387 Kraków, Gronostajowa 2

autor

Tatar Barbara

• Department of Food Chemistry and Nutrition, Medical College, Jagiellonian University, 30-688 Kraków, Medyczna 9

autor

Yildirim Metin

• student from ERASMUS program from Mersin University (Turkey) during stage at Faculty of Pharmacy, Medical College, Jagiellonian University

autor

Sahin Bilge

• student from ERASMUS program from Mersin University (Turkey) during stage at Faculty of Pharmacy, Medical College, Jagiellonian University

autor

Yuksek Nafize Didem

• student from ERASMUS program from Mersin University (Turkey) during stage at Faculty of Pharmacy, Medical College, Jagiellonian University

autor

Ustundag Mustafa

• student from ERASMUS program from Mersin University (Turkey) during stage at Faculty of Pharmacy, Medical College, Jagiellonian University

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