BazTech - Yadda

1

Kropki kwantowe jako narzędzia diagnostyczne

Gruba Natalia, Rejmak Wiktoria, Romanowska Anita, Lesner Adam

Wiadomości Chemiczne

|

2024

|

[Z] 78, 3-4

369--387

EN

The discovery of quantum dots (QDs) was a breakthrough event as it influenced almost every area of our lives. They are used in new technologies, the food industry, clothing production, and finally in medicine. Due to their unique properties, QDs are successfully used in the diagnosis of diseases of various origins - the so-called civilization diseases, infections and cancers. Quantum dots can also serve as tools to monitor the proteolytic activity of enzymes, effectively lowering the detection limit. Our team has been dealing with the proteolytic activity of enzymes for many years, especially in disease diagnosis, for which we also use quantum dots. In this article, we presented the main trends in the use of QDs as diagnostic tools.

2

Wykorzystanie enzymów w diagnostyce medycznej

Gruba Natalia

Wiadomości Chemiczne

|

2023

|

[Z] 77, 1-2

75--96

EN

Each tissue has its own specific enzyme profile. Therefore, the detection of changes in the level of certain enzymes in disease states allows conclusions about the location and type of pathological changes occurring in the body. Only a few (out of several hundred) tissue enzymes are used in routine diagnostics - diagnostics of diseases of the liver, pancreas, skeletal muscles and heart muscle. In practice, this test consists in measuring the activity or determining the level of enzyme protein in body fluids. In this article, the characteristics of a few selected enzymes applicable in clinical practice will be presented.

3

Naciski na podeszwowej stronie stopy osób cierpiących na cukrzycę oraz Zespół Stopy Cukrzycowej

Gajewski Robert, Kwiecień Joanna, Karcz Stanisław, Piotrowska Katarzyna

Przegląd Włókienniczy - Włókno, Odzież, Skóra

|

2023

|

nr 5

28--34

PL

W ramach niniejszej pracy wykonano badania rozmieszczenia nacisków na podeszwowej stronie stopu u osób chorych na cukrzycę. Wydzielono dwie grupy: osoby chore na cukrzycę bez Zespołu Stopy Cukrzycowej (93), oraz osoby z Zespołem Stopy Cukrzycowej (92). Wyniki porównano do grup kontrolnych, sparowanych pod względem masy ciała. Badania wykonano z wykorzystaniem platformy EMED-XL. Analizowano dane o nacisku szczytowym. Wyniki potwierdziły fakt, że osoby z Zespołem Stopy Cukrzycowej mają znacząco wyższe naciski na podeszwowej stronie stopy niż osoby zdrowe. Natomiast w przypadku osób chorych na cukrzyce ale bez objawów Zespołu Stopy Cukrzycowej, w większości przypadków różnice były nieistotne.

EN

In this study, the distribution of pressure on the plantar surface of the foot in people with diabetes was examined. Two groups were distinguished: people with diabetes without Diabetic Foot Syndrome (93), and people with Diabetic Foot Syndrome (92). The results were compared to control groups, paired for body weight. The research was performed using the EMED-XL platform. Peak pressure data were analyzed. The results confirmed the fact that people with Diabetic Foot Syndrome have significantly higher pressures on the plantar side of the foot than healthy people. However, in the case of people with diabetes but without symptoms of Diabetic Foot Syndrome, in most cases the differences were insignificant.

4

Detection of acetone as a potential non-invasive diagnosis tool for diabetes patients

Jali Mohd Hafiz, Zamzuri Ahmad Nur Azeim Ahmad, Rahim Hazli Rafis Abdul, Johari Md. Ashadi Md., Ahmad Aminah, Baharom Mohamad Faizal, Zain Huda Adnan, Harun Sulaiman Wadi

Przegląd Elektrotechniczny

|

2022

|

R. 98, nr 5

71--75

EN

This work investigated the demonstration of acetone detection device as a potential tool to diagnose diabetes patients. It offers simple and low cost approach based on glass substrate platform. The glass substrate was coated with agarose gel as a sensitive material to increase the sensing response. It has superiority in term of high porosity and capable to absorb molecule around it. The sensing mechanism is based on the change in refractive index (RI) of the agarose gel coating layer when exposed to variation acetone concentration level. This is due to the intensity of the light weakening by absorption and scattering when light propagated through the sensing material. The proposed sensor produces a significant response towards acetone concentrations with the output voltage reduced linearly from 1.6V to 1.2V. The sensitivity and resolution of the agarose coated glass substrate improves by a factor of 1.08 and 1.14 respectively as compared to uncoated glass substrate. It also performed better in term of linearity, stability, response time and hysteresis. The non-involvement of costly laser source based instruments make the proposed sensor become more practical for large production while maintaining a good sensing performances. Based on the experiment results, the proposed acetone sensor has a persuasive potential as an early biomarker for diabetes diagnosis tool.

PL

W ramach tej pracy zbadano demonstrację urządzenia do wykrywania acetonu jako potencjalnego narzędzia do diagnozowania pacjentów z cukrzycą. Oferuje proste i tanie podejście oparte na platformie z podłożem szklanym. Szklane podłoże pokryto żelem agarozowym jako wrażliwym materiałem w celu zwiększenia odpowiedzi wykrywania. Ma przewagę pod względem wysokiej porowatości i zdolności do wchłaniania otaczających ją cząsteczek. Mechanizm wykrywania opiera się na zmianie współczynnika załamania światła (RI) warstwy powłoki żelu agarozowego pod wpływem zmian poziomu stężenia acetonu. Wynika to z intensywności osłabienia światła przez absorpcję i rozpraszanie podczas propagacji światła przez materiał czujnika. Proponowany czujnik daje znaczną odpowiedź na stężenia acetonu przy napięciu wyjściowym obniżonym liniowo z 1,6V do 1,2V. Czułość i rozdzielczość podłoża szklanego pokrytego agarozą poprawia się odpowiednio o współczynnik 1,08 i 1,14 w porównaniu z podłożem szklanym niepowlekanym. Działał również lepiej pod względem liniowości, stabilności, czasu odpowiedzi i histerezy. Rezygnacja z kosztownych instrumentów opartych na źródle laserowym sprawia, że proponowany czujnik staje się bardziej praktyczny w przypadku dużych produkcji, przy jednoczesnym zachowaniu dobrych parametrów wykrywania. W oparciu o wyniki eksperymentu, proponowany czujnik acetonu ma potencjał przekonujący jako wczesny biomarker narzędzia diagnostycznego cukrzycy.

5

Expert fuzzy systems for evaluation ofintensity of reactive edema of soft tissues in patients with diabetes

Shkilniak Liudmyla, Wójcik Waldemar, Pavlov Sergii, Vlasenko Oleg, Kanishyna Tetiana, Khomyuk Irina, Bezverkhyi Oleh, Dembitska Sofia, Mamyrbayev Orken, Iskakova Aigul

Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska

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2022

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T. 12, nr 3

59--63

EN

The paper analyzes the main areas of application of mathematical methods inmedical diagnostics, formulates principles of diagnostics basedon fuzzy logic; developed mathematical models and algorithms that formalize the process of making diagnostic decisions based on fuzzy logic with quantitative and qualitative parameters of thepatient's condition; developed mathematicalmodels of membership function. Mathematical modelsand algorithms have been developed that formalize the process of making diagnostic decisions based on fuzzy logic with quantitative and qualitative parameters of the patient's condition; developed mathematical models of membership functions, formalizing the representation of quantitative and qualitative parameters of the patient's condition in the form of fuzzy sets, used in models and algorithms for diagnosis and finding a diagnosis of assessing the intensity of reactive postoperative edema in patients of all study groups. An expert system was implemented for solving the problems of medical diagnosis based on fuzzy logic when assessing the intensity of reactive swelling of soft tissues, which develops in the postoperative period in patientsof all study groups against the background of diabetes.The paper analyzes the main areas of application of mathematical methods in medical diagnostics, formulates the principles of diagnostics based on fuzzy logic.

PL

W pracy analizowane są główne kierunki zastosowania metod matematycznych w diagnostyce medycznej, formułowane są zasady diagnostyki opartej na logice rozmytej; opracowywane są modele matematyczne i algorytmy formalizujące proces podejmowania decyzji diagnostycznych w oparciuo logikę rozmytą z ilościowymi i jakościowymi parametrami stanu pacjenta; opracowywane są modele matematyczne funkcji przynależności. Opracowano modele matematyczne i algorytmy formalizujące proces podejmowania decyzji diagnostycznych w oparciu o logikę rozmytą z ilościowymi i jakościowymi parametrami stanu pacjenta; opracowano modele matematyczne funkcji przynależności formalizujące reprezentację ilościowych i jakościowych parametrów stanu pacjenta w postaci zbiorów rozmytych wykorzystywanych w modelach i algorytmach diagnozowania i znajdowania rozpoznania nasilenia reaktywnego obrzęku pooperacyjnego u pacjentów wszystkich grup badawczych. Wdrożono system ekspercki do rozwiązywania problemów diagnostyki medycznej oparty na logice rozmytej w ocenie nasilenia reaktywnego obrzęku tkanek miękkich, który rozwija się w okresie pooperacyjnymu pacjentów wszystkich grup badawczych z cukrzycą. W artykule przeanalizowano cechy zastosowania metod matematycznych w diagnostyce medycznej, sformułowano zasady diagnostyki opartej na logice rozmytej.

6

Fourier transform-based data augmentation in deep learning for diabetic foot thermograph classification

Anaya-Isaza Andrés, Zequera-Diaz Martha

Biocybernetics and Biomedical Engineering

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2022

|

Vol. 42, no. 2

437--452

EN

Diabetes Mellitus (DM) belongs to the ten diseases group with the highest mortality rate globally, with an estimated 578 million cases by 2030, according to the World Health Organization (WHO). The disease manifests itself through different disorders, where vasculopathy shows a chronic relationship with diabetic ulceration events in distal extremities, being temperature a biomarker that can quantify the risk scale. According to the above, an analysis is performed with standing thermography images, finding temperature patterns that do not follow a particular distribution in patients with DM. Therefore, the modern medical literature has taken the use of Computer-Aided Diagnosis (CAD) systems as a plausible option to increase medical analysis capabilities. In this sense, we proposed to study three state-of-the-art deep learning (DL) architectures, experimenting with convolutional, residual, and attention (Transformers) approaches to classify subjects with DM from diabetic foot thermography images. The models were trained under three conditions of data augmentation. A novel method based on modifying the images through the change of the amplitude in the Fourier Transform is proposed, being the first work to perform such synergy in the characterization of risk in ulcers through thermographies. The results show that the proposed method allowed reaching the highest values, reaching a perfect classification through the convolutional neural network ResNet50v2, promising for limited data sets in thermal pattern classification problems.

7

Diving with Diabetes - A Review of Recommendations

Mańka Ewa, Skuratowicz Bartosz, Kwiatek Sebastian, Krupowies Maciej, Sieroń Karolina

Polish Hyperbaric Research

|

2021

|

nr 1(74)

35--42

EN

Recreational diving is becoming an increasingly popular physical activity around the world. The vast majority of people who practice scuba diving are amateurs, often being treated for a number of chronic diseases and having cardiovascular burdens. Due to the high prevalence of diabetes mellitus in the world population and the potential for dangerous complications during diving, there is a need for unified recommendations for safe diving with this condition. Current guidelines from international diving associations are not entirely consistent. This review presents the positions of international diving associations concerning the requirements for diving with diabetes, the scope of diving and recommended management of life-threatening conditions during the dive.

PL

Nurkowanie rekreacyjne cieszy się coraz większą popularnością. Znacząca większość osób praktykujących nurkowanie to amatorzy, często obciążeni zdrowotnie. Duże rozpowszechnienie cukrzycy wśród populacji oraz znaczące ryzyko wystąpienia u pacjenta poważnych powikłań w trakcie nurkowania niesie ze sobą konieczność ujednolicenia zaleceń dla nurków-cukrzyków. Obecne zalecenia organizacji nurkowych nie są ze sobą całkowicie zgodne. W tej pracy poglądowej omawiamy zalecenia organizacji nurkowych dla pacjentów z cukrzycą z omówieniem zalecanego postępowania w przypadku wystąpienia powikłań cukrzycy podczas nurkowania.

8

Sztuczna inteligencja – pomoc w wykryciu retinopatii cukrzycowej?

Kaczmarek Ewa

Optyka

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2021

|

Nr 6

48--49

PL

Cukrzyca jest chorobą ogólnoustrojową, prowadzi do zmian w ukrwieniu i odżywianiu tkanek. Jej częstym okulistycznym powikłaniem jest retinopatia cukrzycowa (ang. diabetic retinopathy, DR). Amerykańskie Stowarzyszenie Diabetologiczne podało, że retinopatia cukrzycowa jest najczęstszą przyczyną ślepoty u osób w wieku produkcyjnym na świecie. W trakcie jej trwania dochodzi do uszkodzenia i powstania patologicznych naczyń krwionośnych siatkówki. Retinopatię cukrzycową dzielimy na trzy stadia: nieproliferacyjną, przedproliferacyjną i proliferacyjną. Początkowo DR, mimo zmian na dnie oka, nie daje objawów. Jeśli leczenie zostanie wdrożone, gdy zmiany będą zaawansowane, może być ono mało skuteczne, dlatego tak ważna jest szybka i prawidłowa diagnostyka DR.

9

A survey on prediction of diabetes using classification algorithms

Khanwalkar A., Soni R.

Journal of Achievements in Materials and Manufacturing Engineering

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2021

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Vol. 104, nr 2

77--84

EN

Purpose: Diabetes is a chronic disease that pays for a large proportion of the nation's healthcare expenses when people with diabetes want medical care continuously. Several complications will occur if the polymer disorder is not treated and unrecognizable. The prescribed condition leads to a diagnostic center and a doctor's intention. One of the real-world subjects essential is to find the first phase of the polytechnic. In this work, basically a survey that has been analyzed in several parameters within the poly-infected disorder diagnosis. It resembles the classification algorithms of data collection that plays an important role in the data collection method. Automation of polygenic disorder analysis, as well as another machine learning algorithm. Design/methodology/approach: This paper provides extensive surveys of different analogies which have been used for the analysis of medical data, For the purpose of early detection of polygenic disorder. This paper takes into consideration methods such as J48, CART, SVMs and KNN square, this paper also conducts a formal surveying of all the studies, and provides a conclusion at the end. Findings: This surveying has been analyzed on several parameters within the poly-infected disorder diagnosis. It resembles that the classification algorithms of data collection plays an important role in the data collection method in Automation of polygenic disorder analysis, as well as another machine learning algorithm. Practical implications: This paper will help future researchers in the field of Healthcare, specifically in the domain of diabetes, to understand differences between classification algorithms. Originality/value: This paper will help in comparing machine learning algorithms by going through results and selecting the appropriate approach based on requirements.

10

Mining clinical pathways for daily insulin therapy of diabetic children

Deja Rafal, Froelich Wojciech, Deja Grazyna

International Journal of Applied Mathematics and Computer Science

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2021

|

Vol. 31, no. 1

107--121

EN

We propose a decision support framework (DSF) assisting insulin therapy of diabetic children. Our DSF relies on a medical treatment graph (MTG), which models and graphically represents clinical pathways. Using the MTG, it is possible to plan and adapt medical decisions dependent upon the current health state of a patient and the progress of the treatment. Our MTG fits well with the requirements of clinical practice. The presented work is a cooperative effort of researchers in computer science and medicine. The MTG model has been thoroughly tested and validated using real-world clinical data. The usefulness of the approach has been confirmed by physicians.

11

Stem cells in diabetes – will implementing interdisciplinary online collaboration help to dispel ethical resistance?

Kozłowska Ewa, Grabowska Anna, Deutsch Nellie

Engineering of Biomaterials

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2021

|

Vol. 24, no. 163

68

12

Effect of glucose concentration and culture substrate on HUVECs viability in in vitro cultures: A literature review and own results

Ciechanowska Anna, Gora Ilona, Sabalinska Stanislawa, Foltynski Piotr, Ladyzynski Piotr

Biocybernetics and Biomedical Engineering

|

2021

|

Vol. 41, no. 4

1390--1405

EN

Some clinical studies reported that glucose variability increased the risk of developing diabetes-related late complications more than constant hyperglycemia, while others claimed that the evidence was not strong enough to support such a conclusion. A few in vitro studies investigated the effect of constantly high or variable glucose levels (VGLs) on endothelial cells (EC). The first aim of this work was to review these studies and demonstrate that most of them support the notion that viability and other metabolic parameters of EC deteriorate faster in cell cultures with VGLs than in cultures with stable normal or high glucose concentration. The second aim was to verify whether the effect of glucose concentration is the same regardless of other culture conditions such as the substrate on which the cells are grown. We cultured Human Umbilical Vein Endothelial Cells (HUVECs) for 7 or 14 days in constant (5 mM or 20 mM) or variable (switching between 5 mM and 20 mM once a day) glucose concentration in culture plates, which were either not-covered with any additional substrate or were covered with fibronectin or gelatin. We assessed the cell viability using a propidium iodide test. The ANOVA revealed that HUVECs viability was affected not only by glucose concentration and duration of the cell culturing but also by the type of substrate and interactions of these three factors. In conclusion, the effect of glucose level on EC viability should not be analyzed in isolation from other culture conditions that may amplify or attenuate this effect.

13

Działania wspierające zatrudnienie osób z chorobami przewlekłymi

Bugajska Joanna, Łastowiecka-Moras Elżbieta

Bezpieczeństwo Pracy : nauka i praktyka

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2021

|

nr 10

12-16

PL

Choroby przewlekłe w postępujący sposób ograniczają funkcjonowanie człowieka w życiu codziennym, w tym zawodowym. Wywierają duży wpływ na zdolność do wykonywania pracy i tym samym do zarobkowania. Etiologia chorób przewlekłych jest wieloczynnikowa. Istotną rolę w ich powstawaniu pełnią czynniki zawodowe i styl życia. Oddziaływanie na te czynniki stanowi jedno z ważniejszych zadań wspierających zatrudnianie osób z chorobami przewlekłymi. W artykule omówiono główne działania w zakresie promocji zdrowego stylu życia i dostosowania warunków pracy do potrzeb osób z chorobą zwyrodnieniową stawów, z wybranymi chorobami układu sercowo-naczyniowego (chorobą wieńcową i nadciśnieniem tętniczym) oraz z cukrzycą.

EN

Chronic diseases are progressively limiting the functioning of persons suffering from them in everyday life, including work activity. They have a great impact on the ability to perform work, and thus the earnings. The etiology of chronic diseases is multifactorial. Occupational factors and lifestyle play an important role in their formation. Influencing these factors is one of the most important measures supporting the employment of people suffering from chronic diseases. The article discusses the main activities in promoting a healthy lifestyle and adjusting working conditions to the needs of people with osteoarthritis, selected diseases of the cardiovascular system (coronary artery disease and hypertension), and diabetes.

14

Phototherapy in the Treatment of Diabetic Foot - A Preliminary Study

Mikołajczyk Zbigniew, Nowak Iwona, Kawiński Andrzej, Mik Michał

Autex Research Journal

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2021

|

Vol. 21, no. 4

482--490

EN

The first part of the publication presents a substantively insightful literature study on the essence and effects of light waves on wound healing in living organisms, including the use of phototherapy in the treatment of the diabetic foot. A knitted textile dressing was designed and manufactured for phototherapy of patients with diabetes suffering from diabetic foot syndrome (DFS). The proposed solution is intended for the treatment of dermal tissues within the patient's foot affected because of diabetic disease at an early stage. Thus, the use of a knitted dressing with incorporated fiber optic structures and powered by a semiconductor laser emitting a 405 nm light wave from its entire surface would prevent further anomalies of the patient's tissues and help to avoid surgical intervention.

15

Retinopatia cukrzycowa najczęstszą przyczyną utraty wzroku u osób w wieku produkcyjnym

Lemanik Aleksandra

Optyka

|

2020

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Nr 4

50--52

PL

Cukrzyca jest zaliczana do chorób cywilizacyjnych. W Polsce według danych Głównego Urzędu Statystycznego z 2017 roku choruje ponad 2,1 mln (7%) osób powyżej 15. r.ż. [1]. Każdego roku liczba ta wzrasta o około 400 tys., a ponadto szacuje się, że 25% osób nie wie o swojej chorobie. Cukrzyca jest już nazywana epidemią.

16

Heart rate variability features from nonlinear cardiac dynamics in identification of diabetes using artificial neural network and support vector machine

Aggarwal Yogender, Das Joyani, Mazumder Papiya Mitra, Kumar Rohit, Sinha Rakesh Kumar

Biocybernetics and Biomedical Engineering

|

2020

|

Vol. 40, no. 3

1002--1009

EN

Diabetes mellitus (DM) is a multifactorial disease characterized by hyperglycemia. The type 1 and type 2 DM are two different conditions with insulin deficiency and insulin resistance, respectively. It may cause atherosclerosis, stroke, myocardial infarction and other relevant complications. It also features neurological degeneration with autonomic dysfunction to meet metabolic demand. The autonomic balance controls the physiological variables that exhibit nonlinear dynamics. Thus, in current work, nonlinear heart rate variability (HRV) parameters in prognosis of diabetes using artificial neural network (ANN) and support vector machine (SVM) have been demonstrated. The digital lead-I electrocardiogram (ECG) was recorded from male Wister rats of 10–12 week of age and 200 ± 20 gm of weight from control (n = 5) as well as from Streptozotocin induced diabetic rats (n = 5). A total of 526 datasets were computed from the recorded ECG data for evaluating thirteen nonlinear HRV parameters and used for training and testing of ANN. Using these parameters as inputs, the classification accuracy of 86.3% was obtained with an ANN architecture (13:7:1) at learning rate of 0.01. While relatively better accuracy of 90.5% was observed with SVM to differentiate the diabetic and control subjects. The obtained results suggested that nonlinear HRV parameters show distinct changes due to diabetes and hence along with machine learning tools, these can be used for development of noninvasive low-cost real-time prognostic system in predicting diabetes using machine learning techniques.

17

The influence of chronic supply of vanadium compounds on organ weights and body mass in animal diabetes model (NZO)

Krośniak Mirosław, Szklarzewicz Janusz, Gryboś Ryszard, Tatar Barbara, Yildirim Metin, Sahin Bilge, Yuksek Nafize Didem, Ustundag Mustafa

Science, Technology and Innovation

|

2019

|

Vol. 4, no. 1

63--73

EN

Vanadium is an element that has an effect on improving glucose levels in animals with diabetes. However, its operation is strongly dependent on the chemical structure of compounds of this element. The influence of newly synthesized vanadium compounds on biochemical processes is also unknown. The paper presents the influence of eight new vanadium compounds on organ weights of animals (mice NZO) in whom diabetes was induced by a high-fat diet during 8 weeks. Tested vanadium complexes were administered by 5 weeks. After this time organs were collected and weighed. Tested complexes had a remarkable different effect on organ weights, despite having similar composition ([VO(L)(phen)] and the same co-ligand (1,10-phenanthroline) . This indicate on separate metabolic pathways of these compounds in the body of tested animals and role of the tridentate L Schiff base ligands. The compounds C2, C3 and C5 shoved biggest influence on organs weight and these results suggest influence on the metabolic pathways and therefore are interesting for further investigations.

18

The insulin activity model based on insulin profiles

Nowicki Tomasz

Journal of Computer Sciences Institute

|

2019

|

Vol. 13

272--278

EN

The purpose of the research was to propound an insulin activity model in a human body after a subcutaneous injection. A deterministic model in the form of a mathematical function was formulated. The research was based on pharmaceutic publicly available drug information published by the manufactures. The paper presents in detail the model. The obtained results can be used in computer simulations of diabetes mellitus therapy. They suggest that activity models may be assigned to types of insulin instead of separate products.

PL

Celem badań było opracowanie modelu aktywności insuliny w organizmie człowieka po wstrzyknięciu podskórnym. Sformułowano model deterministyczny w postaci funkcji matematycznej. Badanie oparto na publicznie dostępnych informacjach farmaceutycznych opublikowanych przez producentów. Artykuł szczegółowo przedstawia model. Uzyskane wyniki mogą być wykorzystane w komputerowych symulacjach terapii cukrzycy. Sugerują one również, że modele aktywności mogą dotyczyć grup insulin zamiast konkretnych preparatów.

19

Inteligentne polimery i ich stosowanie w kontrolowanym uwalnianiu insuliny podczas leczenia diabetologiczngo

Fajkis N.

Wiadomości Chemiczne

|

2018

|

[Z] 72, 3-4

165--184

EN

This overview will discuss the smart polymers as drug nanocarries, their construction and shapes showing their using for controlled insulin release. The report will focus on diabetes mellitus as a disease unit, its etiology and treatment by injection and by using smart polymers. The ingredients described in this article are: poly- (methacrylic acid-g-ethylene glycol), hyaluronic acid, G-CSF-transferrin conjugate in cultured enterocyte-like Caco-2 monolayers, poly(hydroxybutyrate-co-hydroxyhexanoate) and chitosan. Such “intelligent” polymers and their use in a controlled insulin release in diabetic therapy are immensely promising.

20

Amatorskie nurkowanie pacjentów z rozpoznaną cukrzycą

Ługowska D., Ługowski T., Krzywińska O., Kozakiewicz M., Grzelakowski P.

Polish Hyperbaric Research

|

2018

|

nr 3(64)

39--44

PL

Cukrzyca to „epidemia XXI wieku”, szacuje się, że w 2011 roku na cukrzycę chorowało 6,7% populacji Polski, z czego jedna czwarta nie miała świadomości choroby. Tak duże rozpowszechnienie cukrzycy sprawia, że coraz więcej lekarzy staje przed problemem prawidłowej kwalifikacji pacjenta z cukrzycą do amatorskiego uprawiania sportu, w tym nurkowania. W niniejszej publikacji przedstawiono najważniejsze informacje dotyczące oceny ryzyka, dopuszczenia do amatorskiego nurkowania pacjentów z cukrzycą oraz proponowanych protokołów postępowania przed i podczas uprawiania tego sportu.

EN

Diabetes is an "epidemic of the 21st century" and it is estimated that in 2011 6.7% of Poland's population suffered from diabetes, one quarter of which was unaware of the disease. Such a high prevalence of diabetes mellitus results in an increasing number of physicians being confronted with the problem of qualifying patient with diabetes to partake in amateur sports, including diving. This publication presents the most important information concerning risk assessment, admission of diabetic patients to amateur diving and some proposed protocols of management before and during sport practice.