Genetycznie modyfikowane uprawy i żywność - za i przeciw

Lisowska, K.

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Genetycznie modyfikowane uprawy i żywność - za i przeciw

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Lisowska K.

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Warianty tytułu

Genetically modified crops and food: pros and cons

Konferencja

XII Konferencja ochrona środowiska: przepisy, interpretacje, rozwiązania, trendy

Języki publikacji

Abstrakty

W Polsce kwestia prawnego uregulowania upraw genetycznie zmodyfikowanych roślin (GMO) pozostaje nierozstrzygnięta. Prace nad rządowym projektem nowej ustawy o GMO trwały od roku 2009 i nie zostały zakończone przed upływem kadencji sejmu. Przepisy dotyczące GMO pojawiły się również w ustawie o nasiennictwie, która jednak została zawetowana w sierpniu 2011 roku. Równolegle toczy się bardzo żywa debata nad celowością wprowadzenia GMO do polskiego rolnictwa. Zabierając głos w tej dyskusji zwracam uwagę na niedoskonałości technik inżynierii genetycznej, niedostatek badań z zakresu oceny ryzyka, potencjalne zagrożenia zdrowotne i środowiskowe oraz problemy socjo-ekonomiczne towarzyszące kwestii GM upraw i żywności. Jestem przekonana, że w zakresie legislacji upraw GMO, w żadnym przypadku nie wolno ulegać naciskom politycznym, naciskom międzynarodowych organizacji gospodarczych oraz kół lobbingowych. Wydaje się, że wobec poważnych wątpliwości jakie towarzyszą wykorzystaniu tej technologii w rolnictwie, w Polsce, podobnie jak w wielu innych krajach Europy powinno być nałożone I -letnie moratorium na uprawy odmian GMO. Prawodawstwo UE dostosowuje się w tym zakresie do żądań państw członkowskich i niedługo wejdą w życie przepisy, które umożliwią niezależne podejmowanie decyzji w tej sprawie przez poszczególne państwa.

In Poland genetically modified crops are not regulated by law. Polish Parliament has been discussing the proposal of a new act concerning genetically modified organisms (GMO) since 2009 and did not manage to finalize before the end of its term. Regulations concerning GMOs were also contained in the seed act, but it was vetoed by Polish President. There is also a great debate in the society, whether GM crops are required in Polish agriculture? Taking part in this dispute I review the flaws of the genetic engineering methodology, insufficiency of the risk assessment, potential health and environmental hazards as well as socio-economic and political problems concerning GM crops and food/feed. Certainly, decisions concerning GM crops legislation must not be influenced either politically or by any international economical organizations or corporate lobbies. I am deeply convinced that according to current knowledge, 10-years moratorium should be announced for GM crops cultivation in Poland. This is concerned with potential safety issues and with socio-economical concerns related to Polish agriculture and environment. Similar concerns are raised by several other EU countries and European Commission is close to accept members' right to independent decisions in this matter.

Słowa kluczowe

genetycznie modyfikowane organizmy GMO rolnictwo agrobiznes produkcja żywności rozwój zrównoważony ocena ryzyka moratorium

genetically modified organismus GMO agriculture agribusiness food supply sustainable development risk assessment moratorium

Wydawca

Stowarzyszenie Inżynierów i Techników Przemysłu Chemicznego, ZW CHEMPRESS-SITPChem

Czasopismo

Chemik

Rocznik

2011

Tom

Vol. 65, nr 11

Strony

1193--1203

Opis fizyczny

Bibliogr. 82 poz.

Twórcy

autor

Lisowska K.

Centrum Badań Translacyjnych i Biologii Molekularnej Nowotworów, Centrum Onkologii- Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Bibliografia

1. Malatesta M, Caporaloni C, Rossi L, Battistelli S, Rocchi MB, Tonucci F, Gazzanelli G. Ultrastructural analysis of pancreatic acinar cells from mice fed on genetically modified soybean. J Anat. 2002 Nov;201 (5):409-15.
2. Vecchio L, Cisterna B, Malatesta M, Martin TE, Biggiogera M. Ultrastructural analysis of testes from mice fed on genetically modified soybean. Eur J Histo-chem. 2004 Oct-Dec;48(4):448-54.
3. Cisterna B, Flach F, Vecchio L, Barabino SM, Battistelli S, Martin TE,Malatesta M, Biggiogera M. Can a genetically-modified organism-containing diet influence embryo development? A preliminary study on pre-implantation mouse embryos. Eur J Histochem. 2008 Oct-Dec;52(4):263-7.
4. Malatesta M, Tiberi C, Baldelli B, Battistelli S, Manuali E, Biggiogera M. Reversibility of hepatocyte nuclear modifications in mice fed on genetically modified soybean. Eur J Histochem. 2005 Jul-Sep;49(3):237-42.
5. Malatesta M, Boraldi F, Annovi G, Baldelli B, Battistelli S, Biggiogera M.Quaglino D. A long-term study on female mice fed on a genetically modified soybean: effects on liver ageing. Histochem Cell Biol. 2008 Nov; 130(5):967&7.
6. Malatesta M, Perdoni F, Santin G, Battistelli S, Muller S, Biggiogera M. Hepatoma tissue culture (HTC) cells as a model for investigating the effects of low concentrations of herbicide on cell structure and function. Toxicol In Vitro. 2008 Dec;22(8): 1853-60.
7. Paganelli A, Gnazzo V, Acosta H, Löpez SL, Carrasco AE. Glyphosate-Based Herbicides Produce Teratogenic Effects on Vertebrates by Impairing Retinoic Acid Signaling. Chem Res Toxicol. 2010 Aug 9.
8. Richard S, Moslemi S, Sipahutar H, Benachour N, Seralini GE. Differential effects of glyphosate and roundup on human placental cells and aromatase. Environ Health Perspect. 2005 Jun; 113(6):7l6-20.
9. Marc J, Mulner-Lorillon O, Boulben S, Hureau D, Durand G, Bellé R. Pesticide Roundup provokes cell division dysfunction at the level of CDKI/cyclin B activation. Chem Res Toxicol. 2002 Mar; 15(3):326-31.
10. Benachour N, Séralini GE. Glyphosate formulations induce apoptosis and necrosis in human umbilical, embryonic, and placental cells. Chem Res Toxicol. 2009 Jan;22( I ):97-105.
11. Gasnier C, Dumont C, Benachour N, Clair E, Chagnon MC, Séralini GE. Glyphosate-based herbicides are toxic and endocrine disruptors in human cell lines. Toxicology. 2009 Aug 21;262(3): 184-91.
12. Marc J, Mulner-Lorillon O, Bellé R. Glyphosate-based pesticides affect cell cycle regulation. Biol Cell. 2004 Apr;96(3):245-9.
13. Bellé R, Le Bouffant R, Morales J, Cosson B, Cormier P, Mulner-Lorillon O. [Sea urchin embryo, DNA-damaged cell cycle checkpoint and the mechanisms initiating cancer development]. J Soc Biol. 2007;201 (3): 317-27.
14. Marc J, Bellé R, Morales J, Cormier R Mulner-Lorillon O. Formulated glyphosate activates the DNA-response checkpoint of the cell cycle leading to the prevention of G2/M transition. Toxicol Sci. 2004 Dec;82(2): 436-42.
15. Mañas F, Peralta L, Raviolo J, Garcia Ovando H, Weyers A, Ugnia L, Gonzalez Cid M, Larripa I, Gorla N. Genotoxicity of AMPA, the environmental metabolite of glyphosate, assessed by the Comet assay and cytogenetic tests. Ecotoxicol Environ Saf. 2009 Mar;72(3):834-7.
16. Mañas F.; Peralta L.; Garcia Ovando H.; Weyers A.; Ugnia L.; Larripa I.; Gonzalez Cid M.; Gorla N. Genotoxicity of Glyphosate assessed by the comet assay and cytogenetic tests. Environmental Toxicology and Pharmacology 28 (2009): 37-41.
17. Lajmanovich RC, Sandoval MT Peltzer PM. Induction of mortality and malformation in Scinax nasicus tadpoles exposed to glyphosate formulations. Bull Environ Contam Toxicol. 2003 Mar;70(3):612-8.
18. Biological effects of transgenic maize NK603xMON8I0 fed in long term reproduction studies in mice Redakcja: Dr. A. Velimirov, Dr. C. Binter, Univ. Prof. Dr. J. Zentek. Zespół badawczy: N. Cyran, Dr. C. Gülly, Dr. S. Handl, G. Hofstätter, F. Meyer, Dr. M. Skalicky, Prof. Dr. R. Steinborn, Department/ Universitätsklinik für Nutztiere und öffentliches Gesundheitswesen in der Veterinärmedizin, Forschungsinstitut für biologischen Landbau - FiBL
19. VAZQUES-PARDON R.I., GONZALEZ-CABRERA J., GARCIA-TOVAR C., NERI-BAZAN L., LOPEZ-REVILLA R., HERNANDEZ M., MORENO-FIERROS L., DE LA RIVA. G.A. 2000 a. Cry I Ac protoxin from Bacillus thuringiensis sp. kurstaki HD73 binds to surface proteins in the mouse small intestine. Biochem Biophys Res Commun. 271(1): 54-8.
20. Aris A, Leblanc S. Maternal and fetal exposure to pesticides associated to genetically modified foods in Eastern Townships of Quebec, Canada. Reprod Toxicol. 2011 Feb 18.
21. Ewen SW, Pusztai A. Effect of diets containing genetically modified potatoes expressing Galanthus nivalis lectin on rat small intestine. Lancet. 1999 Oct 16;354(9187): 1353-4.
22. Magaña-Gomez JA, Cervantes GL, Yepiz-Plascencia G, de la Barca AM. Pancreatic response of rats fed genetically modified soybean. J Appl Toxicol. 2008 Mar;28(2):2l7-26.
23. Vecchio L, Cisterna B, Malatesta M, Martin TE, Biggiogera M. Ultrastructural analysis of testes from mice fed on genetically modified soybean. Eur J Histochem. 2004 Oct-Dec;48(4):448-54.
24. Kiliç A & Akay MT (2008). A three generation study with genetically modified Bt corn in rats: Biochemical and histopathological investigation. Food Chem Toxicol. 46: 1164-70.
25. Sagstad A, Sanden M, Haugland O, Hansen AC, Olsvik PA, Hemre GI. J: Evaluation of stress- and immune-response biomarkers in Atlantic salmon, Salmo salar L., fed different levels of genetically modified maize (Bt maize), compared with its near-isogenic parental line and a commercial suprex maize. Fish Dis. 2007 Apr;30(4):201-12.
26. Vázquez RI, Moreno-Fierros L, Neri-Bazán L, De La Riva GA, López-Revilla R. Bacillus thuringiensis Cry I Ac protoxin is a potent systemic and mucosal adjuvant. Scand J Immunol. 1999 Jun;49(6):578-84.
27. Nordlee JA, Taylor SL, Townsend JA, Thomas LA, Bush RK. Identification of a Brazil-nut allergen in transgenic soybeans. N Engl J Med. 1996 Mar I4;334(l l):688-92. Cisterna B, Flach F, Vecchio L, Barabino SM, Battistelli S, Martin TE,
28. VAZQUES-PARDON R.I., MORENO-FIERROS L., NERI-BAZAN L., MARTINEZ-GIL A.F., DE LA RIVA G.A., LOPEZ-REVILLA R. 2000 b. Characterization of the mucosal and systemic immune response induced by Cry I Ac protein from Bacillus thuringiensis HD 73 in mice. BrazJ Med Biol Res. 33(2): 147-55.
29. Prescott VE, Campbell PM, Moore A, Mattes J, Rothenberg ME, Foster PS, Higgins TJ, Hogan SP. Transgenic expression of bean alpha-amylase inhibitor in peas results in altered structure and immunogenicity. J Agric Food Chem. 2005 Nov l6;53(23):9023-30.
30. Séralini GE, de Vendmois JS, Cellier D, Sultan C, Buiatti M, Gallagher L, Antoniou M, Dronamraju KR. How subchronic and chronic health effects can be neglected for GMOs, pesticides or chemicals. Int J Biol Sci. 2009 Jun 17;5(5):438-43. Review.
31. Domingo JL. Toxicity studies of genetically modified plants: a review of the published literature. Crit Rev Food Sci Nutr. 2007;47(8):72l-33. Review.
32. de Vendômois JS, Roullier F, Cellier D, Séralini GE. A comparison of the effects of three GM corn varieties on mammalian health. Int J Biol Sci. 2009 Dec 10;5(7):706-26.
33. Dona A & Arvanitoyannis IS (2009). Health risks of genetically modified foods. Crit Rev Food Sci Nutr. 49:164-75.
34. WALTZ E. 2009. Under Wraps, Nature Biotechnology 27(10): 880’882.
35. DO Seed Companies Control GM Crop Research? 2009. Scientific American Magazine, www.scientificamerican.com/article.cfm?id=do-seed-companies-control-gm-crop-research
36. Netherwood T, Martin-Orúe SM, O'Donnell AG, Gockling S, Graham J, Mathers JC, Gilbert HJ. Assessing the survival of transgenic plant DNA in the human gastrointestinal tract. Nat BiotechnoL 2004 eb;22(2): 204-9.
37. Tudisco R., Mastellone., Cutrignelli M.I, Lombardi P, Bovera F, Mirabella N., Piccolo I G., Calabro, S., Avallone L., Infascelli F, 2010, Fate of transgenic DNA and evaluation of metabolic effects in goats fed genetically modified soybean and in their offsprings. Animal 2010
38. Chainark, P. (2008) Availability of genetically modified feed ingredient II: investigations of ingested foreign DNA in rainbow trout Oncorhynchus mykiss. Fisheries Science, 74(2): 380-390(11)
39. Ran,T, Mei, L., Lei, W., Aihua, L., Ru, H., Jie, S (2009) Detection of transgenic DNA in tilapias (Oreochromis niloticus, GIFT strain) fed genetically modified soybeans (Roundup Ready). Aquaculture Research, Volume 40 (12): 1350-1357
40. Mazza R, Soave M, Morlacchini M, Piva G, Marocco A. Assessing the transfer of genetically modified DNA from feed to animal tissues. Transgenic Res. 2005 Oct;l4(5):775-84.
41. Sharma R, Damgaard D, Alexander TW, Dugan ME, Aalhus JL, Stanford K, McAllister TA. Detection of transgenic and endogenous plant DNA in digesta and tissues of sheep and pigs fed Roundup Ready canola meal. J Agric Food Chem. 2006 Mar 8;54(5): 1699-709.
42. Schubbert R, Hohlweg U, Renz D, Doerfler W. On the fate of orally ingested foreign DNA in mice: chromosomal association and placental transmission to the fetus. Mol Gen Genet. 1998 Oct;259(6):569-76.
43. WOLFENBARGER L.L., PHIFER RR. 2000 The ecological risks and benefits of genetically engineered plants. Science. 290(5499): 2088-93.
44. Ferré J, Van Rie J. Biochemistry and genetics of insect resistance to Bacillus thuringiensis. Annu Rev Entomol. 2002;47:501-33. Review.
45. Griffitts JS, Aroian RV. Many roads to resistance: how invertebrates adapt to Bt toxins. Bioessays. 2005 Jun;27(6):6l4-24. Review.
46. Heckel DG, Gahan LJ, Baxter SW, Zhao JZ, Shelton AM, Gould F, Tabashnik BE. The diversity of Bt resistance genes in species of Lepidoptera. J Invertebr Pathol. 2007 Jul;95(3): 192-7. Epub 2007 Mar 25. Review
47. Downes S, Mahon R, Olsen K. Monitoring and adaptive resistance management in Australia for Bt-cotton: current status and future challenges. J Invertebr Pathol. 2007 Jul;95(3):208-13. Review.
48. Tabashnik BE, Van Rensburg JB, Carriére Y. Field-evolved insect resistance to Bt crops: definition, theory, and data. J Econ Entomol. 2009 Dec; 102(6):2011 -25. Review.
49. Gaines TA, Zhang W, Wang D, Bukun B, Chisholm ST, Shaner DL, Nissen SJ, Patzoldt WL, Tranel PJ, Culpepper AS, Grey TL, Webster TM, Vencill WK, Sammons RD, Jiang J, Preston C, Leach JE, Westra P. Gene amplification confers glyphosate resistance in Amaranthus palmeri. Proc Natl Acad Sci U SA. 2010 Jan 19; 107(3): 1029-34.
50. Jenczewski E, Ronfort J, Chévre AM. Crop-to-wild gene flow, introgression and possible fitness effects of transgenes. Environ Biosafety Res. 2003 Jan-Mar;2(l):9-24. Review
51. Arnaud JF, Viard F, Delescluse M, Cuguen J. Evidence for gene flow via seed dispersal from crop to wild relatives in Beta vulgaris (Chenopodiaceae): consequences for the release of genetically modified crop species with weedy lineages. Proc Biol Sci. 2003 Aug 7;270( 1524): 1565-71.
52. Gepts P, Papa R. Possible effects of (trans)gene flow from crops on the genetic diversity from landraces and wild relatives. Environ Biosafety Res. 2003 Apr-Jun;2(2):89-103.
53. Séralini GE, Cellier D, de Vendomois JS. New analysis of a rat feeding study with a genetically modified maize reveals signs of hepatorenal toxicity. Arch Environ Contam Toxicol. 2007 May;52(4):596-602.
54. PINEYRO-NELSON A., VAN HEERWAARDEN J., PERALES H.R., SERRATOS-HERNANDEZ J.A., RANGEL A., HUFFORS M.B., GEPTS R, GARAY-ARROYO A., RIVERA-BUSTAMANTE R., ALVAREZ-BUYLLA E.R. 2009. Transgenes in Mexican maize: molecular evidence and methodological considerations for GMO detection in landrace populations. Mol Ecol. 18(4): 750’61.
55. QUIST D, CHAPELA I. 2001. Transgenic DNA introgressed into traditional maize landraces in Oaxaca, Mexico. Nature 414: 541-543
56. Snow A (2009). Unwanted transgenes re-discovered in Oaxacan maize. Molecular Ecology 18: 569-571.
57. Serratos-Hernández JA, Gómez-Olivares JL, Salinas-Arreortua N, Buendia-Rodriguez E, Islas-Gutiérrez F & de-Ita A (2007). Transgenic proteins in maize in the Soil Conservation area of Federal District, Mexico. Frontiers in Ecology and the Environment 5: 247-252.
58. Galeano P, Martinez Debat C, Ruibal F, Franco Fraguas L & Galván GA (2011). Cross-fertilization between genetically modified and non-genetically modified maize crops in Uruguay. Environmental Biosafety Research DOI: 10.1051/ ebr/2011100 Published online by Cambridge University Press: March 2011
59. Gealy DR, Mitten DH and Rutger JN (2003). Gene Flow Between Red Rice (Oryza sativa) and Herbicide-Resistant Rice (O. sativa): Implications for Weed Management. Weed Technology 17:627-645.
60. ROSI-MARSHALL, E. J., TANK J.L., ROYER T.V., WHILES M.R., EVANS-WHITE M., CHAMBERS C., GRIFFITHS N.A., POKELSEK J., STEPHEN M.L. 2007. Toxins in transgenic crop byproducts may affect headwater stream ecosystems. Proc Natl Acad Sci USA 104(41): 16204-8
61. SAJI H., NAKAJIMA N., AONO M., TAMAOKI M., KUBO A., WAKIYAMA S., HATASE Y., NAGATSU M. 2005. Monitoring the escape of transgenic oilseed rape around Japanese ports and roadsides. Environ Biosafety Res. 4(4): 217-22.
62. Yoshimura Y, Beckie HJ & Matsuo K (2006). Transgenic oilseed rape along transportation routes and port of Vancouver in western Canada. Environ Biosafety Res. 5: 67-75.
63. Aono M, Wakiyama S, Nagatsu M, Nakajima N, Tamaoki M, Kubo A & Saji H (2006). Detection of feral transgenic oilseed rape with multiple-herbicide resistance in Japan. Environ Biosafety Res. 5: 77-87
64. Bohn T., Primicerio R., Hessen D.O. & T. Traavik (2008): Reduced fitness of Daphnia magna fed a Bt-transgenic maize variety. Arch. Environ. Contam. Toxicol. 55:584l&92
65. Lövei GL, Arpaia S (2005) The impact of transgenic plants on natural enemies: a critical review of laboratory studies. Entomol Exp Applic 114:1-14
66. Marvier, M., McCreedy, C., Regetz, J., Kareiva P. (2007): A meta-analysis of effects of Bt cotton and maize on non-target invertebrates. Science 316: 1475-1477.
67. Benamú MA, Schneider Ml & Sánchez NE (2010). Effects of the herbicide glyphosate on biological attributes of Alpaida veniliae (Araneae, Araneidae), in laboratory. Chemosphere 78: 871-876.
68. Bøhn T, Traavik T & Primicerio R (2010). Demographic responses of Daphnia magna fed transgenicBt-maize. Ecotoxicology 19:419-430.
69. Relyea RA (2005). The lethal impact of roundup on aquatic and terrestrial amphibians. Ecological Applications 15: 1118-1124.
70. National Research Council. 2010. The Impact of Genetically Engineered Crops on Farm Sustainability in the United States. Washington, DC: The National Academies Press
71. Economic Impact of Dominant GM Crops Worldwide: a Review. EUR 22547 EN Manuel Gómez-Barbero, Emilio Rodriguez-Cerezo. EUROPEAN COMMISSION DG JRC-IPTS, Sustainability in Agriculture, Food and Health Unit December 2006
72. Failure to yield: Evaluating the Performance of Genetically Engineered Crops. Doug Gurian-Sherman, Union of Concerned Scientists, April 2009
73. The Organic Center Critical Issue Report: The magnitude and impact of the biotech and organic organic seed price premium, Charles Benbrook, December 2009).
74. The Organic Center Critical Issue Report: Impacts of Genetically Engineered Crops on Pesticide Use in the United States: The First Thirteen Years, Charles Benbrook November 2009
75. Michael Antoniou, Paulo Brack, Andrés Carrasco, John Fagan, Mohamed Habib, Paulo Kageyama, Carlo Leifert, Rubens Onofre Nodari, Walter Pengue: GM Soy - Sustainable? Responsible? GLS Gemeinschaftsbank eG www. gls.de / ARGE Gentechnik-frei www.gentechnikfrei.at

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