Ethylene oxide-containing (co)polymers in controlled drug delivery.

Stachurek, I.; Pielichowski, K.

Artykuł - szczegóły

Tytuł artykułu

Ethylene oxide-containing (co)polymers in controlled drug delivery.

Autorzy

Stachurek I. , Pielichowski K.

Identyfikatory

Warianty tytułu

Języki publikacji

Abstrakty

Application of polymeric marterials in contemporary medicine and pharmacy has broadened due to their advantageous properties that can be adjusted through e.g. conditions of synthesis. One of the most important biomedical polymers is poly(ethylene oxide) (PEO) which is a biocompatible, non-toxic and water soluble polymer. PEO and its copolymers are used in drug delivery systems as polymer matrix, in which the drug is loaded. Different forms of polymeric drug carriers are distinguished - micro- and nanospheres, capsules or micelles from which the drug is released by slow decomposition of the matrix and simultaneous diffusion. Currently, nanostructured drug delivery systems are intensively investigated to explain the mechanism of drug delivery. In the review synthesis, properties and applications of ethylene oxide-based polymeric materials in selected drug delivery systems are described.

Słowa kluczowe

polymers biomedical polymers medicine pharmacy drug delivery

polimery polimery biomedyczne medycyna farmacja podawanie leku

Wydawca

Komitet Nauki o Materiałach PAN

Czasopismo

Archives of Materials Science

Rocznik

2005

Tom

Vol. 26, nr 4

Strony

303--327

Opis fizyczny

Bibliogr. 92 poz., rys.

Twórcy

autor

Stachurek I.

Cracow University of Technology, Faculty of Environmental Engineering, ul. Warszawska 24, 31-155 Kraków

autor

Pielichowski K.

Department of Chemistry and Technology of Polymers, Cracow University of Technology, Warszawska 24, 31-155 Kraków, Poland

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Typ dokumentu

Bibliografia

Identyfikator YADDA

bwmeta1.element.baztech-article-BOS5-0010-0046