Usefulness of chest perfusion computed tomography in the diagnosis of diabetic pulmonary microangiopathy

• Autorzy: Kalicka R. , Browarczyk M. , Lipiński S.

Identyfikatory

DOI

10.1016/j.bbe.2014.08.005

• Języki publikacji: EN

Abstrakty

EN

This paper presents the usefulness of perfusion computed tomography (pCT) in the diagnosis of diabetic pulmonary microangiopathy. Our previous works have shown that perfusion parameters are useful in the diagnosis of diabetic pulmonary microangiopathy. We are looking for such measurements and perfusion parameters that provide the most accurate diagnosis. Two types of comparison were made based on the results of clinical trials: non-diabetic vs. diabetic and diabetes without microangiopathy vs. diabetes with microangiopathy. Our studies have shown that PS (permeability surface) is only perfusion parameter statistically significant. In certain regions of interest logistic regression as a classifier produces very good results in diagnosing lung microangiopathy: sensitivity Sens = 89% and excellent specificity Spec = 100%. The results were obtained on the base of measurements taken from 23 subjects. These results were compared with results reported in the literature and based on diffusion capacity and spirometry measurements and modeling. None of the previous results was as good as those obtained using the PS and logistic regression for binary classification.

Słowa kluczowe

EN

chest perfusion computed; tomography; PCT; pulmonary microangiopathy; diabetes mellitus; lung

PL

tomografia komputerowa; pCT; mikroangiopatia płucna; cukrzyca; płuco

• Wydawca: Nałęcz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences ; Elsevier
• Czasopismo: Biocybernetics and Biomedical Engineering
• Rocznik: 2015
• Tom: Vol. 35, no. 1
• Strony: 68--73
• Opis fizyczny: Bibliogr. 16 poz., rys., tab., wykr.

Twórcy

autor

Kalicka R.

• Department of Biomedical Engineering, Faculty of Electronics, Telecommunications and Informatics, Gdańsk University of Technology, 11/12 Gabriela Narutowicza St., 80-233 Gdańsk, Poland

autor

Browarczyk M.

• Department of Biomedical Engineering, Faculty of Electronics, Telecommunications and Informatics, Gdańsk University of Technology, 11/12 Gabriela Narutowicza St., 80-233 Gdańsk, Poland

autor

Lipiński S.

• Department of Electrical and Power Engineering, Faculty of Technical Sciences, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland

Bibliografia

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