Wyniki wyszukiwania - Biblioteka Nauki

1

Ultrastructural studies on the phagocytosis of human spermatozoa by Trichomonas vaginalis

100%

Szreter H. , Dworniczek E. , Kassner J.

Acta Parasitologica

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1994

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tom 39

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nr 2

2

The influence of arginine vasopressin (AVP) on phagocytosis in the unicellular Tetrahymena

88%

Jahn I. , Csaba G.

Acta Protozoologica

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1987

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tom 26

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nr 1

3

Molecular modifications of host cells by Toxoplasma gondii

88%

Dlugonska H.

Polish Journal of Microbiology

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2004

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tom 53

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nr Suppl.

EN

Toxoplasma gondii, the etiological agent of toxoplasmosis, is an Apicomplexa obligate intracellular protozoan parasite, which is able to infect any nucleated cell of numerous endothermic vertebrates. The combined abilities to actively penetrate host cells and perfectly control the fate of the parasite-containing vacuole (parasitophorus vacuole, PV) contribute to the remarkable global success of Toxoplasma as an intracellular parasite. Very broad host range and the relative ease of growth both in cell cultures in vitro and in vivo suggest that the parasite is able to manipulate the host cell apoptotic machinery. The article describes different aspects of host-parasite interplay focusing on molecular modifications of infected host cells.

4

Histiocytic Ulcerative Gastroenterocolitis and Dermatoneoplasm in Boxer Dog - Clinical Case Report

88%

Kozak M. , Levkut M. , Revajova V. , Magic D.

Medycyna Weterynaryjna

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2003

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tom 59

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nr 12

5

Participation of 125 kDa tyrosine-phosphorylated protein in phagocytosis of Acanthamoeba cells

88%

Krawczynska W. , Sobota A.

Folia Histochemica et Cytobiologica. Supplement

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1996

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tom 34

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nr 1

6

Phagocytosis of neutrophils in rabbits infected with antigenic variants of RHD (rabbit haemorrhagic disease) virus

75%

Niedzwiedzka-Rystwej P. , Deptula W.

Polish Journal of Veterinary Sciences

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2012

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tom 15

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nr 1

EN

The present study was aimed at determining changes in chosen elements of phagocytosis in rabbits infected with 3 antigenic variants of RHD – Hartmannsdorf, Pv97 and 9905, which differed in haemagglutination ability. The animals were tested for phagocytosis parameters, and the results revealed that the examined strains showed the differences. These variations regarded mainly Pv97 strain, as the intensity of the changes were 5 times stronger in comparison to strain Hartmannsdorf and 9905. As all of the strains examined are signified as antigenic variants, we have stated that this feature does not determine their immunological picture. The results suggest the existence of immunological dissimilarities among strains of the RHD virus, which was revealed for the first time in antigenic variants.

7

The influence of selenium compounds of different structure on morphology, blood biochemistry and phagocytic capability of granulocytes in rats

75%

Musik I. , Kielczykowska M. , Donica H.

Roczniki Państwowego Zakładu Higieny

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2013

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tom 64

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nr 2

EN

Background. Selenium belongs to important microelements. Numerous studies have revealed relationships between its deficiency and occurrence of diverse illnesses, but the question of the proper form and dose of Se-supplementation still remains unsolved. Objective. In the present study the influence of different selenium compounds on blood morphology and biochemistry as well as on phagocytic capacity of granulocytes and NBT test in rats was investigated. Material and methods. Adolescent male Wistar rats were divided into four groups (ten animals each): I – control, received saline; II – received sodium selenite Na2SeO3; III – received selenoorganic compound A of chain structure 4-(o-tolyl-)-selenosemicarbazide of 2-chlorobenzoic acid; IV – received selenoorganic compound B of cyclic structure 3-(2-chlorobenzoylamino-)- 2-(o-tolylimino-)-4-methyl-4-selenazoline. The administration was performed by stomach tube at a dose of 5 · 10-4 mg Se g-1 b.w. once a day for 10 days. Results. Selenium compounds treatment decreased haematocrit. Erythrocytes number was unchanged in all groups receiving Se vs. control, whereas leucocytes number was depressed in groups II and IV. Haemoglobin was significantly decreased in group III. White blood count was altered in groups II and III, where all parameters were markedly decreased except for lymphocytes in group III and remained unchanged in group IV. The outcomes regarding selenium effect on biochemistry parameters of blood showed that urea remained unchanged, glucose was statistically decreased in groups II and III, whereas cholesterol was significantly diminished in group II and increased in group III vs. control. Results concerning phagocytosis and NBT test displayed that % of positive cells were decreased in groups II and III, whereas remained unaltered in group IV vs. control. Conclusions. As cyclic selenoorganic compound B did not cause many significant changes of the studied parameters it may be suggested that after further researches it could be taken into account as a possible selenium supplement.

PL

Wprowadzenie. Selen należy do mikropierwiastków o dużym znaczeniu dla organizmu. Badania naukowe wykazały istnienie zależności pomiędzy niedoborem selenu a występowaniem wielu poważnych schorzeń, jednakże kwestia doboru odpowiedniej formy i dawki stosowanej w suplementacji nadal pozostaje nierozwiązana. Cel. W przeprowadzonym doświadczeniu badano wpływ podawania różnych związków selenu na morfologię krwi i biochemię krwi oraz zdolności fagocytarne granulocytów i test NBT u szczurów. Materiał i metody. Młode szczury samce rasy Wistar podzielono na cztery grupy (po 10 zwierząt): I – kontrola, otrzymywała sól fizjologiczną; II – otrzymywała selenian(IV) sodu Na2SeO3; III – otrzymywała organiczny związek selenu A o budowie łańcuchowej 4-(o-tolilo-)-selenosemikarbazyd kwasu 2-chlorobenzoesowego; IV - otrzymywała organiczny związek selenu B o budowie cyklicznej 3-(2-chlorobenzoiloamino-)-2-(o-toliloimino-)-4-metylo-4-selenazolinę. Związki podawane były sondą dożołądkowo w dawce 5 · 10-4 mg Se g-1 m.c. raz dziennie przez okres 10 dni. Wyniki. Podawanie związków selenu obniżyło hematokryt. Liczba erytrocytów we wszystkich grupach pozostała niezmieniona w stosunku do kontroli a liczba leukocytów była zmniejszona w grupach II i IV. Poziom hemoglobiny został obniżony statystycznie w grupie III. Obraz białych elementów morfotycznych w porównaniu do kontroli uległ zmianie w grupach II i III gdzie wszystkie wskaźniki zostały istotnie statystycznie obniżone za wyjątkiem limfocytów w grupie III, natomiast w grupie IV nie zaobserwowano żadnych zmian. Analizując wpływ podawania selenu na parametry biochemiczne krwi stwierdzono, że stężenie mocznika pozostało niezmienione. Stężenie glukozy w przypadku grup II i III uległo istotnemu statystycznie obniżeniu. Stężenie cholesterolu w II grupie było istotnie obniżone a w III podwyższone w porównaniu z kontrolą. Badania fagocytozy i wyniki testu NBT wykazały, że % pozytywnych komórek uległ obniżeniu w grupach II i III w stosunku do grupy kontrolnej i pozostał niezmieniony w grupie IV. Wnioski. Ponieważ organiczny związek cykliczny B nie spowodował istotnych statystycznie zmian wielu badanych parametrów można byłoby sugerować, że przeprowadzenie dalszych badań pozwoli rozważyć jego zastosowanie jako suplementu selenu.

8

Saccharomyces cerevisiae - a model organism for the studies on vacuolar transport.

75%

Kucharczyk R. , Rytka J.

Acta Biochimica Polonica

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2001

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tom 48

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nr 4

1025-1042

EN

The role of the yeast vacuole, a functional analogue of the mammalian lysosome, in the turnover of proteins and organelles has been well documented. This review provides an overview of the current knowledge of vesicle mediated vacuolar transport in the yeast Saccharomyces cerevisiae cells. Due to the conservation of the molecular transport machinery S. cerevisiae has become an important model system of vacuolar trafficking because of the facile application of genetics, molecular biology and biochemistry.

9

The effect of pretreatment of Tetrahymena pyriformis with colistin on the incorporation of this antibiotic into the cell membrane

75%

Szablewski L.

Acta Protozoologica

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1988

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tom 27

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nr 3-4

10

Modulation of phagocytosis in Tetrahymena thermophila by histamine and the antihistamine diphenhydramine

75%

Buduma N. , Balabanian J. , Dalvi P. , Chia S.-K. , Dhaliwal A. , Boothby J. , Bros-Seemann S. , Kibler R. , Khuri S. , Veregge S.

Acta Protozoologica

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2013

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tom 52

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nr 4

11

The site of action of colistin on Tetrahymena pyriformis

75%

Szablewski L.

Acta Protozoologica

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1988

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tom 27

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nr 1

12

Pharmacological specificity of beta blockers-induced inhibition of Paramecium phagocytosis

75%

Wyroba E.

Acta Protozoologica

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1989

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tom 28

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nr 2

13

The interaction of synbiotic of the environment and the endoecosystem as one of the mechanisms of action of balneotherapy

75%

Popovych I. L. , Zukow W. A. , Fil V. M. , Kovalchuk H. Y. , Bryndzia I. V. , Voloshyn O. R. , Kopko I. Y. , Lupak O. M. , Skrobach T. B.

European Journal of Clinical and Experimental Medicine

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2023

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nr 2

315-323

EN

Introduction and aim. Drinking mineral waters are one of the environmental factors that affect the condition of the human body. Of particular interest are therapeutic waters of the Naftussya type, which contain autochthonous microbes and organic oil-like substances and can be considered as a kind of ecosystem. On the other hand, gastrointestinal tract also is an ecosystem that associates a resident microbiota and cells of various phenotypes lining the epithelial wall. We assumed that one of the mechanisms of the therapeutic effect of Naftussya water is the interaction of external and internal ecosystems. This article is the first in a series in support of the hypothesis. Material and methods. The object of clinical-physiological observation were residents of the city of Truskavets’ (21 men aged 24-67 years and 8 women 33-76 years) with chronic pyelonephritis in remission. The objects of study: leukocyturia, bacteriuria, components of microbiota, phagocytosis function of neutrophils, leukocytary adaptation index, plasma and urine electrolytes and nitrogenous metabolites. Results. The weekly use of bioactive Naftussya water from the Opaka deposit causes a favorable normalizing effect on the stool microbiota: it increases the reduced content of Bifidobacteria and Lactobacilli, instead it reduces the increased content of pathogenic strains of Escherichia coli, as well as Klebsiela and Proteus. Reduction of dysbacteriosis is accompanied by an increase in the reduced bactericidal capacity of blood neutrophils against E. coli and Staphylococcus aureus, and reduction of bacteriuria and leukocyturia. At the same time, the elevated level of creatinine in the plasma decreases, instead, the decreased levels of sodium and chloride increase. As expected, the daily diuresis and excretion of urea, creatinine, phosphates, calcium, magnesium and chloride increases, but not sodium and uric acid, the concentrations of which in the urine decrease. The described physiologically beneficial effects are interpreted as adaptogenic, which is confirmed by an increase in the reduced leukocyte adaptation index. Conclusion. The healing effect of Naftussya bioactive water is the result of the interaction of external and internal ecosystems. The next article will consider the role of the nervous and endocrine systems in this interaction.

14

Pathological changes in the microstructure of pale, soft, exudative (PSE) and normal turkey breast muscle

75%

Gorska M. , Wojtysiak D.

Folia Biologica

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2017

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tom 65

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nr 3

15

Fcgamma receptor mediated activation of human polymorphonuclear neutrophils [PMN]

75%

Schubert J. , Hundt M. , Schmidt R. E.

Archivum Immunologiae et Therapiae Experimentalis

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1992

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tom 40

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nr 1

16

Phagocytosis and microbicidal capacity of human neutrophils in contact allergy to pesticides

75%

Tos-Luty S. , Latuszynska J. , Sobczynska B. , Przylepa E. , Bychawski E. , Lecewicz-Torun B. , Chodorowska G.

Annals of Agricultural and Environmental Medicine

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1995

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tom 02

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nr 2

17

Natural mannose-binding lectin [MBL] down-regulates phagocytosis of Helicobacter pylori

75%

Strapagiel D. , Grebowska A. , Rozalska B. , Bak-Romaniszyn L. , Czkwianianc E. , Planeta-Malecka I. , Rechcinski T. , Rudnicka W. , Chmiela M.

Polish Journal of Microbiology

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2006

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tom 55

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nr 2

EN

Considering the role of lectin-carbohydrate interactions between Helicobacter pylori bacteria and the host cells we addressed the question on how mannose binding lectin - MBL, present in human plasma, may influence the phagocytosis of H. pylori by peripheral blood granulocytes. For phagocytosis assay the granulocytes separated from peripheral blood of healthy H. pylori-seronegative donors were used. Phagocytosis was estimated by fluorescence assay using FITC-labelled H. pylori cells. The MBL level in the serum samples as well as MBL-binding to H. pylori bacteria were estimated by ELISA. In this study all H. pylori isolates bound recombinant mannose binding lectin-MBL as shown by ELISA. The ingestion of H. pylori bacteria in the medium with human serum depleted in natural MBL (nMBL) was more intensive than in the medium with complete serum containing nMBL. Moreover, the ingestion of H. pylori bacteria in the medium with complete serum was increased by an addition of anti-rMBL IgG. The results indicate that interaction of bacterial and host lectins may regulate the phagocytosis of H. pylori bacteria and in this way influence an outcome of the infection caused by these microbes.

18

cGMP-dependent hydrolysis of cyclic nucleotides in peritoneal macrophages

75%

Wroblewska H. , Kobialka M. , Gorczyca W. A.

Cellular and Molecular Biology Letters

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2002

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tom 07

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nr Suppl.

19

Activity of neutrophilic granulocytes in rats following intoxication with vanadium and zinc

75%

Zaporowska H. , Scibior A.

Folia Histochemica et Cytobiologica

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1999

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tom 37

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nr 2

20

Neutrophils in the innate immune response

75%

Kobayashi S. C. , Voyich J. M. , Burlak C. , DeLeo F. R.

Archivum Immunologiae et Therapiae Experimentalis

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2005

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tom 53

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nr 6