Wyniki wyszukiwania - Biblioteka Nauki

1

Szczepionki genetyczne

100%

Osek J.

Medycyna Weterynaryjna

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1996

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tom 52

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nr 09

549-552

2

Wplyw wielokrotnego podawania dimeru lizozymu na pierwotna odpowiedz humoralna myszy immunizowanych SRBC

88%

Obminska-Domoradzka B. , Switala M. , Debowy J.

Medycyna Weterynaryjna

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1998

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tom 54

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nr 11

757-760

EN

The study aimed at determining the effect of a multiple dose of lysozyme dimer (Lydium-KLP Nika Health Products) on primary humoral response in SRBC - immunized mice. The effects of a single (20 µg/kg) lysozyme dimer administered 2 h prior to antigen injection were compared with those of lysozyme dimer multiple doses (two-four) administered at one week intervals. The results of the study show that lysozyme dimer, irrespective of the number and range of the doses (2, 20 or 200 µg/kg) enhances humoral response to the antigen. The adjuvant action of lysozyme dimer is expressed in the increasing number of splenocytes producing hemolytic antibodies (PFC) and the total and 2-mercaptoethanol resistant level of anti-SRBC hemagglutinins. The strongest activation of the immune response was observed after a single administration and multiple injections at doses of 2 or 20 µg/kg. Three doses of lysozyme dimer (200 µg/kg each) injected at 7-day intervals decreased the number of PFC induced by this drug administered in a single dose of 20 µg/kg 2 h prior to immunization, but maintaining the potentializing impact on anti-SRBC antibody production. The results obtained in the study indicate that multiple doses of lysozyme dimer administered in doses recommended in veterinary practice (2-20 µg/kg), at 7-day intervals do not results in immunological tolerance.

3

Przypadki choroby krwotocznej zajecy w hodowli kwaterowej - proby profilaktyki

75%

Majer-Dziedzic B. , Buczek J. , Dziedzic R. , Zietek J.

Medycyna Weterynaryjna

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2006

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tom 62

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nr 07

807-810

EN

The viral etiology of the disease was established on the basis of virological, anatomopathological, and bacteriological examinations. The isolated aetiological agent of the European Brown Hare Syndrome virus (EBHS; Calicivirdae, Logovirus) was used to produce its own vaccine against EBHS. The vaccine was used to immune 82 hares and eliminated the mortality rate of EBHS infected hares under controlled conditions. The study confirmed the minor pathogenicity of the EBHS virus for rabbits and indicated the presence of cross-immune reactions between the EBHS and RHD viruses.

4

Wplyw immunizacji przeciw influenzie koni na parametry odpornosci komorkowej

75%

Zaleska M. , Anusz K. , Kita J.

Medycyna Weterynaryjna

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1995

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tom 51

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nr 02

90-93

EN

Six thoroughbred horses formed a study group which was immunized twice with a vaccine (Equigrip, Rhone-Merieux), the control group was six unvaccinated horses. Blood was collected for hematological examinations, cellular immune responses, specific humoral immunity (HI) at days 0, 17, 34, 83, 117 and 123 of the experiment. On day 117 of the experiment, 3 horses of the experimental group and 3 horses of the control group were infected intranasally with a mixture of 2 subtypes (A-l and A-2) of the influenza virus. It is worth noting that 17 days after the first vaccination the lymphocyte stimulation index increased in all horses in the experimental group, while in four of the six unvaccinated horses (control) the index decreased. During this time a statistically significant increase of the specific antibodies titres was not found in vaccinated horses. Six days after the infection, the fairly high level of specific humoral immunity was accompanied by a strong stimulation of cellular immunity, which was expressed as a statistically significant increase in the lymphocyte stimulation index (as determined by the specific blastic transformation test) and was higher in vaccinated horses. Reisolation of the virus, which was attempted five days after the challenge from the nasal cavities of vaccinated horses was unsuccessful, while influenza virus subtype 2 was isolated from each of the vaccinated horses.

5

Szczepionki DNA w prewencji chorob pasozytniczych: stan obecny i perspektywy

75%

Wedrychowicz H. , Kofta W.

Wiadomości Parazytologiczne

|

1998

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tom 44

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nr 2

175-180

EN

The introduction of genetic or "naked DNA" vaccines may open a new era in vaccinology. DNA vaccination is a relatively simple process: a recombinant vector containing cDNA of the potentially protective pathogen antigen, is delivered to a host organism under the control of a strong promoter. It has been demonstrated that the introduced DNA remains stable as an episome for a long time and does not integrate into a genome of vaccinated organism. The type of immune response elicited by DNA vaccination depends very much on the antigen used and on the way of the vaccine delivery. Generally, DNA vaccination induces Tol-dependent rather than Th2-dependent immune response. DNA vaccines present many advantages over "traditional" ones. Firstly, it is easier to obtain a considerable amount of DNA than similar quantities of purified protective antigen protein. Secondly, the antigenic proteins synthesised within the host cell possess an appropriate molecular structure and undergo a posttranslational modifications specific for the native protein. The posttranslational modifications, for example glycosylation, cannot be introduced during expression of the recombinant protein antigens in bacterial hosts.

6

Schematy szczepień u koni

75%

Pedziwiatr R.

Weterynaria w Praktyce

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2009

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tom 06

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nr 03

7

Zastosowanie rekombinowanego bialka VP60 wirusa RHD do immunizacji krolikow

75%

Fitzner A. , Gromadzka B. , Kesy A. , Brycka E. , Szewczyk B.

Medycyna Weterynaryjna

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2005

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tom 61

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nr 06

706-710

8

Sposob na leczenie swin

75%

Wierzchoslawski K.

Farmer

|

2008

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nr 04

75-76

9

Szczepienia in ovo - nowa technika immunizacji drobiu

75%

Borzemska W. B. , Szeleszczuk P.

Medycyna Weterynaryjna

|

1999

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tom 55

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nr 01

15-18

10

Construction of a k-immunization strategy with the highest convexity

75%

Zaremba L.

Control and Cybernetics

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1998

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tom Vol. 27, no 1

135-144

EN

Assuming that interest rate shocks are proportional to their values plus one, we prove in Theorem 1 the existence of and construct a portfolio Z[sup *] with the highest convexity in the class of portfolios that solve the immunization problem to meet the liability to pay C dollars K years from now. Z[sup *] appears to be a barbell strategy with two zero-coupon bonds with the shorest and the longest maturities. This intuitively clear result has been obtained here in a rigorous way by means of the K-T conditions. In addition, we show that our result is stricly related to the problem of maximization of the unanticipated rate of return on a portfolio solving the above immunization problem (Theorem 2). Two more results concerning the unanticipated return after K years are provided with proofs. An example illustrating the role of convexity in maximization of the unanticipated return is included. Despite the fact that there exists a pretty vast literature on bond portfolio strategies, the present paper offers a new methodological approach to this area (see Ingersoll, Skelton, Weil, 1978).

11

Otrzymywanie immunogennych komórek nowotworowych za pomocą cyklofosfamidu

75%

Kawalec M. , Skorski T. , Hoser G.

Postępy Biologii Komórki

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1989

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tom 16

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nr 1

12

Wpływ immunizacji świń zawiesiną wyselekcjonowanych szczepów Yersinia enterocolitica na przebieg doświadczalnego zakażenia oraz okres siewstwa drobnoustrojów

75%

Platt-Samoraj A. , Szweda W. , Procajlo Z. , Mikulska-Skupien E. , Bancerz-Kisiel A. , Szczerba-Turek A. , Syczylo K.

Medycyna Weterynaryjna

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2013

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tom 69

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nr 09

EN

Y. enterocolitica infection of pigs is concerned with a common carrier and shedding states in this species. The aim of the study was to determine the influence of the experimental immunization of pigs with a selected Y. enterocolitica strains suspension on the controled infection course, the antibody level formation, as well as the duration of pathogen shedding. The immunization of pigs was enforced with a suspension of Y. enterocolitica strains previously inactivated with formol, suspended in PBS and demonstrated in vitro high immunogenicity in Respiratory Burst Activity/Potential Killing Activity (RBA/PKA) and Mitogen Transformation Test (MTT). The study was performed on 15 pigs divided into 3 groups. The animals from groups I and II received an immunizate with a density of 2.7 × 10⁹ cfu/ml administered subcutaneously in doses 2 ml and 5 ml, respectively, twice in a 2-week interval. The third group (control) was administered PBS in an analogous scheme. The evaluation in vivo was conducted after a per os challenge with a pathogenic strain of Y. enterocolitica O:3. The first and booster immunization had no effect on the clinical picture and body weight gains of the immunized animals. The fastest and strongest immune response to the per os challenge with Y. enterocolitica O:3 was observed in the control group, already in the first week post infection (wpi). Higher antibody levels were found in the group of animals where 5 ml 2.7 × 10⁹ cfu/cm³ subcutaneously were administered. In the first wpi bacterial shedding was observed in all animals that belonged to group I and the control group which persisted up to 3 wpi. Among the pigs from group II the shedding was observed in 3 out of 5 animals, and which finished in 6 days post infection. Applied experimental immunization against per os challenge with a pathogenic strain of Y. enterocolitica O:3 did not prevent pathogen shedding, but merely limited its intensity and duration.

13

Assets/liabilities portfolio immunization as an optimization problem

75%

Kondratiuk-Janyska A. , Kałuszka M.

Control and Cybernetics

|

2006

|

tom Vol. 35, no 2

335-349

EN

The aim of this paper is to present bond portfolio immunization strategies in the case of multiple liabilities, based on single-risk or multiple-risk measure models under the assumption of multiple shocks in the term structure of interest rates referring, in particular, to Fong and Vasicek (1984), Nawalkha and Chambers (1996), Balbas and Ibanez (1998) and Hurlimann (2002). Immunization problem is formulated as a constrained optimization problem under a fixed open loop strategy. New risk measures associated with changes of the term structure are also defined.

14

Rola bakterii Streptococcus mutans w patogenezie prochnicy

75%

Zandecka-Dziubak J. , Tomaszewska M. , Lipinski D. , Mrozikiewicz P. M.

Herba Polonica

|

2004

|

tom 50

|

nr 2

94-110

PL

W Polsce i na świecie próchnica została uznana za chorobę społeczną. Badania z udziałem ludzi potwierdziły, że za inicjację i postępowanie tej choroby odpowiedzialne są bakterie Streptococcus mutans. Wiele analiz wskazuje na kluczową rolę specyficznych białek S. mutans (antygen 1/11, glukozylotrasferaza GTF, białka GBP) w patogenezie próchnicy. Badania dowiodły, że antygeny te bądź ich fragmenty mogą być efektywnymi immunogenami przeciwko próchnicy.

EN

Dental caries was recognized as a social problem in Poland and in the world. Streptoccocus mutans and Streptococcus sobrinus were strongly implicated as the causative organisms of human and animal dental caries. Specific proteins of S. mutans (antigen l/ll and glucosyltransferase GTF, GBP-proteins) have been implicated as the virulence factors in the molecular pathogenesis of dental caries. A lot of investigations indicated that the antigens or its fragments can be effective immunogenes against caries.

15

Szczepienie matek zwierzat domowych

75%

Larski Z.

Medycyna Weterynaryjna

|

1996

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tom 52

|

nr 09

543-548

16

Regulacja odpowiedzi immunologicznej przez przeciwciala antyidiotypowe

63%

Salwa J.

Kosmos

|

1992

|

tom 41

|

nr 4

371-381

17

Immunogennosc rekombinowanych komorek klonu AG przeciwko zakazeniu wirusem BLV

63%

Rulka J. , Buzala E.

Medycyna Weterynaryjna

|

1999

|

tom 55

|

nr 11

742-745

18

Niektore wskazniki odpornosci karpi po immunizacji antygenami Aeromonas sp.

63%

Kozinska A.

Medycyna Weterynaryjna

|

2000

|

tom 56

|

nr 09

598-602

19

Występowanie izohemolizyn u krów immunizowanych białkami surowicy krwi

63%

Wegrzyn Z. , Slota E. , Wegrzyn J.

Roczniki Naukowe Zootechniki

|

1980

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tom 07

|

nr 2

20

Preventive vaccination of foxes against rabies – economic and environmental aspects

63%

Flis M.

Ekonomia i Środowisko

|

2018

|

tom nr 1

220--230

EN

The thesis presents the analysis of the oral immunization effectiveness, taking cognizance of wild foxes. The preventive measures conducted 15 years ago have significantly contributed to the substantial decline in the number of verified cases of rabies among wild and domestic animals. Despite the fact, that aforementioned measures have been generating high costs covered by the state’s founds, they dramatically reduced the risk of epizootic danger, thus epidemiological risks. Undertaken actions also led to the dynamic growth of population of foxes, which resulted in a kind of disruption of natural ecological system concerning the ‘predator – prey’ relation, therefore they have indirectly contributed to the deepening of the already ongoing contraction of the basic small animals.