Wyniki wyszukiwania - Biblioteka Nauki

1

Growth factors related to some herpes viruses

100%

Golais F. , Lesko J. , Gasperik J.

Folia Histochemica et Cytobiologica. Supplement

|

1997

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tom 35

|

nr 2

2

Interferon alpha in the establishment of latency by herpes simplex virus type 1 strain tr.

100%

Wieczorek M. , Litwinska B.

Polish Journal of Microbiology

|

2006

|

tom 55

|

nr 1

EN

The effect of interferon (IFN) alpha on the establishment and maintenance of neuronal latency and viral reactivation is still not known. Using cell culture methods and sensitive RT-PCR methods, we show that the presence of antiserum to IFN alpha promotes the establishment of HSV-1 tr latent infection. We suggest that IFN alpha is an important tool not only for the control of productive but also latent HSV-1 infection.

3

Occurrence of Marek’s disease in Poland on the basis of diagnostic examination in 2015–2018

86%

Kozdrun W. , Stys-Fijol N. , Czekaj H. , Piekarska K. , Niczyporuk J. S. , Stolarek A.

Journal of Veterinary Research

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2020

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tom 64

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nr 4

4

Human herpesvirus type 8 seroprevalence among patients in immunosuppression state

86%

Trzcinska A. , Litwinska B.

Acta Microbiologica Polonica

|

2001

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tom 50

|

nr 3-4

301-303

5

Survival rate of Suid Herpesvirus (SuHV-1, Aujeszky`s disease virus, ADV) in composted sewage sludge

86%

Paluszak Z. , Lipowski A. , Ligocka A.

Polish Journal of Veterinary Sciences

|

2012

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tom 15

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nr 1

EN

Sewage sludge constitutes a source of valuable biogenic raw materials, but it is a carrier of many pathogenic microorganisms and viruses. Subjected to an effective sanitization by means of the process of composting, it is suitable to use in agriculture as fertilizers. The aim of this study was to observe the survival rate of Suid Herpesvirus under the influence of the temperature alone (water bath) as well as in sewage sludge subjected to the process of composting (pile). The samples were taken at different time intervals, and the virus titres were determined. The viruses survived considerably longer under laboratory conditions: at 30°C as long as 21 days, at 40°C - 93 hours, and at 50°C - less than an hour. In the compost pile, in spite of the lack of the thermophylic phase, the total survival time of the viruses ranged from 34 to 44.5 hours, which indicates the vast importance of other physicochemical factors, apart from the temperature, contributing to virus inactivation.

6

Animal herpesviruses and their potential use as polyvalent recombinant vaccines

86%

Zelnik V. , Kopacek J. , Koptidesova D. , Smith G. D. , Ross L. J. N. , Pastorek J.

Bulletin of the Veterinary Institute in Puławy

|

1998

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tom 42

|

nr 1

7

The UL97 protein kinase of human cytomegalovirus [HCMV] and homologues in other herpesviruses: relevance for virus and host

86%

Michel D. , Mertens T.

Cellular and Molecular Biology Letters

|

2003

|

tom 08

|

nr 2A

8

Impact of cyprinid herpesvirus-3, which causes interstitial nephritis and gill necrosis, on the activity of carp (Cyprinus carpio L.) macrophages and lymphocytes

72%

Siwicki A. K. , Kazun K. , Kazun B. , Majewicz-Zbikowska E.

Archives of Polish Fisheries

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2012

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tom 20

|

nr 2

9

Presence of Herpesvirus anguillae (AngHV1) DNA in the native ichthyofauna of North-Western Poland

72%

Tuan N. T. , Kempter J. , Panicz R.

Electronic Journal of Polish Agricultural Universities. Series Fisheries

|

2016

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tom 19

|

nr 4

10

HybProbes-based real-time PCR assay for rapid detection of equine herpesvirus type 2 DNA

72%

Osinska E. , Golke A. , Slonska A. , Cymerys J. , Banbura M. W. , Dzieciatkowski T.

Polish Journal of Veterinary Sciences

|

2012

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tom 15

|

nr 3

EN

Equid herpesvirus type 2 (EHV-2) together with equid herpesvirus type 5 are members of Gammaherpesvirinae subfamily, genus Rhadinovirus. EHV-2 is one of major agents causing diseases of horses common worldwide. A possible role of EHV-2 in reactivating latent equid herpesvirus type-1 has been suggested, because reactivation of latent EHV-1 was always accompanied by EHV-2 replication. Variety techniques, including cell culture, PCR and its modifications, have been used to diagnose EHV-2 infections. The aim of this study was to develop, optimize and determine specificity of real-time PCR (qPCR) for EHV-2 DNA detection using HybProbesR chemistry and to evaluate clinical samples with this method. The analytical sensitivity of assay was tested using serial dilutions of viral DNA in range between 70 and 7x105 copies/ml. The limit of detection (LOD) was calculated using probit analysis and was determined as 56 copies/ml. In further studies 20 different clinical samples were tested for the presence of EHV-2. Described in-house qPCR method detected viral DNA in 5 of 20 specimens used. The results of this work show that developed HybProbes-based real-time PCR assay is very reliable and valuable for detection and quantification of equid herpesvirus type 2 DNA in different clinical samples. The high level of sensitivity, accuracy and rapidity provided by the LightCycler 2.0 instrument are favorable for the use of this system in the detection of EHV-2 DNA in veterinary virology.

11

Differences in the expression of human papillomavirus type 16 (HPV-16) E6 oncogene mRNA in SiHa cell line inoculated with CMV, HSV or ureaplasmas

72%

Szostek S. , Zawilinska B. , Biernat-Sudolska M. , Kopec J. , Kleszcz E. , Koprynia M. , Rojek-Zakrzewska D. , Kosz-Vnenchak M.

Folia Biologica

|

2014

|

tom 62

|

nr 1

12

Viral and cellular kinases play a central role in VZV pathogenesis and are targets for antiviral kinase inhibitors

72%

Moffat J. F. , Taylor S. L. , Leisenfelder S.

Cellular and Molecular Biology Letters

|

2003

|

tom 08

|

nr 2A

13

Viral and host-cell protein kinases: enticing antiviral targets

72%

Shugar D.

Cellular and Molecular Biology Letters

|

1998

|

tom 03

|

nr 3

14

The potential of acyclic nucleoside phosphonates as broad-spectrum antiviral agents

72%

Naesens L. , Balzarini J. , De Clercq E.

Postępy Biochemii

|

1995

|

tom 41

|

nr 5

15

Homologues of HSV-1 nuclear egress factor UL34 are potential phosphoinositide-binding proteins

72%

Wyrwicz L. S. , Koczyk G. , Rychlewski L.

Acta Biochimica Polonica

|

2008

|

tom 55

|

nr 1

16

New approaches to the prevention and treatment of viral diseases

58%

Pronin A. V. , Narovlyansky A. N. , Sanin A. V.

Archivum Immunologiae et Therapiae Experimentalis

|

2021

|

tom 69

|

nr 1

17

Detection of beta-herpesviruses in Polish adult cord blood stem cell recipients by real-time PCR: single centre study

58%

Dzieciatkowski T. , Przybylski M. , Basak G. W. , Torosian T. , Tomaszewska A. , Jedrzejczak W. W. , Mlynarczyk G.

Archivum Immunologiae et Therapiae Experimentalis

|

2010

|

tom 58

|

nr 6

467-472

18

Five year serological study of bovine herpesvirus type-1 in cattle in Lithuania

58%

Jacevicius E. , Salomskas A. , Milius J. , Petkevicius S. , Jaceviciene I. , Pridotkas G. , Mockeliunas R. , Malakauskas A. , Morkunas M.

Bulletin of the Veterinary Institute in Puławy

|

2010

|

tom 54

|

nr 3

EN

A serological study of BoHV-1 distribution was conducted in Lithuania from 2005 to 2009. Antibody level was measured using a commercial ELISA. For serological examination, 15,368 random blood samples from cattle of different age, gender, and size of herd, which was unvaccinated against IBR, were collected in 37 districts. It was registered that 11.97% of BoHV-1 were seropositive samples. It was also shown that BOHV-1 is most widespread in cattle herds with population >200 individuals (14.79%). Comparison of different sex groups of cattle revealed that the highest number of infected animals was identified in cows (34.64%) and the lowest in bulls (2.01%). In heifers the number of infected animals was 10.01% and in calves - 4.41%. It was shown that seroprevalence of BoHV-1 infection in Lithuania increased with age of animals. The highest prevalence of BoHV-1 (53.98%) was registered in cattle aged more than 7 years.

19

The xCELLigence system for real-time and label-free analysis of neuronal and dermal cell response to Equine Herpesvirus type 1 infection

58%

Golke A. , Cymerys J. , Slonska A. , Dzieciatkowski T. , Chmielewska A. , Tucholska A. , Banbura M. W.

Polish Journal of Veterinary Sciences

|

2012

|

tom 15

|

nr 1

EN

Real-time cell electronic sensing (RT-CES) based on impedance measurements is an emerging technology for analyzing the status of cells in vitro. It allows label-free, real time monitoring of the biological status of cells. The present study was designed to assess dynamic data on the cell processes during equine herpesvirus type 1 (EHV-1) infection of ED (equine dermal) cells and primary murine neuronal cell culture. We have demonstrated that the xCELLigence system with dynamic monitoring can be used as a rapid diagnostic tool both to analyze cellular behavior and to investigate the effect of viral infection.

20

Herpesviruses as possible cofactors in HPV-16-related oncogenesis

58%

Szostek S. , Zawilinska B. , Kopec J. , Kosz-Vnenchak M.

Acta Biochimica Polonica

|

2009

|

tom 56

|

nr 2

337-342

EN

Cervical carcinogenesis is a complex problem with papillomavirus widely accepted as a causative agent. Integration of a human papillomavirus (HPV) of the high-risk type into the host cell genome is one of the major contributing factors to cervical malignant transformation. In this study, the correlation of CMV, EBV, HSV-1, HSV-2, HHV-6 and HHV-7 infections with the physical status of the HPV genome in cervical cancer and precancerous cervical lesions was investigated in sixty HPV-16-positive women. Cervical secretion samples were submitted to DNA extraction and analyzed by PCR. HPV-16 DNA was confirmed in genotyping with the reverse hybridization line probe assay. Multiplex PCR with specific primers for the E2/E6 genes was used to assess the viral integration status of HPV-16. Our results show that CMV DNA was more frequently present in samples with mixed forms of HPV-16 than in the episomal form (P < 0.025). Such a correlation was also observed in the case of EBV (P < 0.005). The presence of CMV resulted in a six-fold (OR 6.069; 95% CI 1.91-19.22; P = 0.002), while EBV caused a seven-fold (OR 7.11; 95% CI 1.70-29.67; P = 0.007) increase in the risk of the integrated or mixed HPV-16 genome occurrence. Our data suggest that coinfection with herpesviruses, especially CMV and EBV, may be involved in the integration of the HPV-16 genome and may contribute to the development of cervical cancer.