Wyniki wyszukiwania - Biblioteka Nauki

1

Wplyw enrofloksacyny na przeciwdrgawkowe dzialanie diazepamu

100%

Wlaz P. , Rolinski Z.

Medycyna Weterynaryjna

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1995

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tom 51

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nr 10

596-597

EN

Enrofloxacin, a fluoroquinolone derivative exhibiting a broad spectrum of antibacterial activity, is known to induce several adverse neurologic side effects, such as psychomotor excitation, restlessness in animals, and hallucinations in humans. These side effects are probably attributable to the impaired GABA-ergic neurotransmission. This prompted us to study the effects of acute administration of enrofloxacin upon the antiepileptic efficacy of diazepam, an agent acting through an enhancement of GABA-ergic transmission, in maximal elektroshock-induced seizures in mice. All drugs were injected intraperitoneally at a volume of 10 ml/kg 60 min prior to the seizure test. A convulsive response, expressed as CC50 (defined by the lowest current intensity (in mA) necessary to produce the tonic hindlimb extension) was then determined. Enrofloxacin given alone in a dose of 50 mg/kg did not affect the seizure threshold as compared to the value abtained following saline treatment (11.6 mA and 12.0 mA, respectively). Administration of diazepam at a dose of 10 mg/kg resulted in a significant elevation of the seizure threshold, which reached 42.2 mA (p<0.05 versus saline- or enrofloxacin-treated animals). However, when mice were given a combination of both drugs, the protective activity of diazepam was diminished, which was reflected by a significant decrease in the convulsive current (21.7 mA; p<0.05 versus diazepam-treated mice). These data strongly suggest that the anticonvulsant properties of diazepam are reversed by concomitant treatment with enrofloxacin. Moreover, this might argue against the use of such antimicrobial agents in animals suffering from different types of seizure disorders.

2

Antagonistic activity of lactic acid bacteria on strains of Yersinia enterocolitica o:3 isolated from slaughtered pigs

100%

Jakubczak A. , Kot B. , Bukowski K.

Advances in Agricultural Sciences

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1996

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tom 05

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nr 1

31-35

3

Rola mikroorganizmow anatagonistycznych w zwalczaniu chorob roslin

86%

Pieta D.

Roczniki Akademii Rolniczej w Poznaniu. Ogrodnictwo

|

1998

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tom 27

221-227

4

Nowa metoda oceny antagonistycznego dzialania bakterii kwasu mlekowego [LAB] na wybrane, chorobotworcze bakterie wskaznikowe

86%

Strus M.

Medycyna Doświadczalna i Mikrobiologia

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1998

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tom 50

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nr 1-2

123-130

PL

Porównano 3 metody badania antagonistycznego działania bakterii kwasu mlekowego na drobnoustroje wskaźnikowe, będące przykładami najczęstszych czynników etiologicznych zakażeń przewodu pokarmowego i narządu rodnego człowieka. Zaproponowana przez nas, nowa metoda słupkowa dawała, po przeprowadzeniu badań porównawczych i analizy statystycznej, najbardziej zwarte i powtarzalne wyniki, a także umożliwiała badanie szeregu bakterii wskaźnikowych o szczególnych wymaganiach odżywczych i atmosferycznych.

EN

A comparison was made of three methods: paper disc, double layer and a newly proposed agar slab techniques for testing antibacterial activity of Lactobacillus strains. Strains of indicator bacteria were selected from important pathogens of the human alimentary and genitourinary tract. The agar slab method, which is based on applying of slabs of MRS agar with overnight growth of the antagonistic bacteria to the surface of appropriate agar plates seeded with indicator bacteria, appeared to be the only method suitable for testing of aerobic and anaerobic fastidious bacteria. After testing of 27 Lactobacillus strains against 3 selected indicator bacteria: E. coli, Salmonella enteritidis and Staphylococcus aureus, calculating mean values and standard deviations for diameters of inhibitory zones and making variance analysis it was shown that in comparison to other methods the agar slab technique, although less sensitive than others, gave most consistent and reproducible results.

5

Drożdże jako czynniki ochrony biologicznej roślin

86%

Kordowska-Wiater M.

Postępy Mikrobiologii

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2011

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tom 50

|

nr 2

6

Interakcje lekow roslinnych stosowanych w chorobach ukladu oddechowego

72%

Blecharz-Klin K. , Piechal A. , Pyrzanowska J. , Widy-Tyszkiewicz E.

Herba Polonica

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2005

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tom 51

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nr 3-4

87-105

EN

Leki roślinne są często stosowane w terapii schorzeń układu oddechowego. Gdy są przyjmowanie jednocześnie z lekami konwencjonalnymi, zwiększa to ryzyko wystąpienia interakcji ze składnikami farmakologicznie czynnymi roślin leczniczych. Na podstawie zarówno wyników badań klinicznych, jak i doświadczeń przedklinicznych omówiono najczęściej używane preparaty pochodzenia roślinnego. Przedstawiono najczęstsze interakcje wpływające w znacznym stopniu na przebieg terapii schorzeń układu oddechowego.

PL

Herbs are often used in therapies of respiratory system disorders. Concurrent use of conventional drugs enhance the risk of revealing herb-drug interactions. The review deals with the most popular herbal remedies supporting the results of clinical trials and the preclinical experiments as well. Common drug interactions that have potential clinical significance in respiratory diseases are discussed.

7

Bioaktywne metabolity ryzosferowych bakterii Pseudomonas

72%

Jankiewicz U.

Woda - Środowisko - Obszary Wiejskie

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2010

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tom 10

|

nr 2[30]

83-92

8

Trichoderma - ukryty sprzymierzeniec

72%

Majewski A.

Hasło Ogrodnicze

|

2009

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nr 10

28-30

9

Characterization of cobalt-copper antagonism in the study of copper-simulated growth in weanling pigs

72%

Kornegay E. T. , Zhou W. , Swinkles J. W. G. M. , Risley C. R.

Journal of Animal and Feed Sciences

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1995

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tom 04

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nr 1

21-33

10

Laboratoryjna ocena antagonistycznego dzialania niektorych grzybow na patogeny grzybowe nasion buraka cwiklowego

72%

Janas R.

Biuletyn Warzywniczy

|

1996

|

tom 45

59-70

11

Grzyby z rodzaju Trichoderma jako czynnik ograniczajacy wystepowanie Fusarium oxysporum Schl.f.sp. gerberae [Gordon] w uprawie gerbery

72%

Kurzawinska H. , Klima E.

Zeszyty Naukowe Akademii Rolniczej w Krakowie. Ogrodnictwo

|

1997

|

tom 23

93-99

12

Oddzialywanie saprofitycznych izolatow Fusarium oxysporum Schlecht. na izolaty F. oxysporum powodujace wiedniecie gipsowki i gozdzikow

72%

Werner M.

Roczniki Akademii Rolniczej w Poznaniu. Ogrodnictwo

|

2000

|

tom 32

65-73

13

Antagonistyczne dzialanie bakterii fermentacji mlekowej w stosunku do wybranych drobnoustrojow

72%

Kot B. , Jakubczak A. , Bukowski K.

Medycyna Weterynaryjna

|

2000

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tom 56

|

nr 01

53-57

EN

Nine strains of lactic acid bacteria isolated from raw pork and beef were the subject of the study. The antagonistic activity of the tested strains was determined against pathogenic bacteria: Staphylococcus aureus (MRSA and MSSA), enteropathogenic E. coli and Listeria monocytogenes. A modified Spelhaugh and Harlander method was used. The research was carried at anaerobic conditions and with the solid medium MRS-0.2. The lactic acid bacteria strains, which showed the largest antibacterial activity on the solid medium, were used for research in MRS-0.2 broth and minced beef. Pediococcus pentosaceus W24, Lactobacillus sp. W27, Lactobacillus brevis F4 strains showed the largest antibacterial activity against enteropathogenic E. coli strains on the solid medium. In MRS-0.2 broth in the presence of Lactobacillus sp. W27 (ltFCFU/ml) the growth of E. coli 6B0124:K72 was completely inhibited after five days of incubation. The number of Listeria monocytogenes cells in the presence of Pediococcus pentosaceus F50 (106CFU/ml) was lower than that of the control sample during the first two days. Incubation during the next four days resulted in an increase of the number of Listeria monocytogenes cells (6xl07CFU/ml) but the number of cells did not exceed the number of cells in the control sample (109CFU/ml). The antagonistic activity of these strains under investigation in minced beef was restricted. The growth of total of MRSA strains and majority of MSSA strains was inhibited by Pediococcus pentosaceus F50 and Lactobacillus brevis F14 strains on the solid medium MRS-0.2. In MRS-0.2 broth in the presence of Pediococcus pentosaceus F50 (106CFL/ml) the growth of MRSA 3 strain was completely inhibited after four days of incubation.

14

Antagonistyczna aktywnosc wybranych grzybow z rodzaju Trichoderma wzgledem Fusarium oxysporum f.sp. dianthi powodujacego wiedniecie gipsowki [Gypsophila paniculata L.]

72%

Werner M.

Roczniki Akademii Rolniczej w Poznaniu. Ogrodnictwo

|

2001

|

tom 34

137-147

15

Oddzialywanie sidy [Sida hermaphrodita Rusby] na drobnoustroje glebowe

72%

Wielgosz E.

Annales Universitatis Mariae Curie-Skłodowska. Sectio E. Agricultura

|

1996

|

tom 51

183-189

16

Antagonistyczne dzialanie bakterii z rodzaju Lactobacillus wobec beztlenowych i mikroaerofilnych czynnikow zakazen przewodu pokarmowego [Helicobacter pylori, Campylobacter coli, Campylobacter jejuni, Clostridium difficile]

72%

Strus M. , Pakosz K. , Gosciniak H. , Przondo-Mordarska A. , Rozynek E. , Pituch H. , Meisel-Mikolajczyk F. , Heczko P. B.

Medycyna Doświadczalna i Mikrobiologia

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2001

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tom 53

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nr 2

133-142

PL

Określono antagonistyczne właściwości bakterii z rodzaju Lactobacillus, wyizolowanych z kału zdrowych noworodków karmionych mlekiem matki, wobec najczęstszych beztlenowych i mikroaerofilnych etiologicznych czynników zakażeń przewodu pokarmowego. Stwierdzono, że większość z przebadanych szczepów Lactobacillus w warunkach in vitro wykazuje wyraźne antagonistyczne działanie wobec badanych szczepów wskaźnikowych tj. Helicobacter pylori, Campylobacter coli, Campylobacter jejuni i Clostridium difficile.

EN

Antagonistic activity of Lactobacillus strains has been known for some time. This property is connected with production of many active substances by lactobacilli e.g., organic acids and bacteriocin-like substances which interfere with other indigenous microorganisms inhabiting the same ecological niche, including also anaerobic gastrointestinal tract pathogens. Growing interest of clinical medicine in finding new approaches to treatment and prevention of common inflammatory infections of the digestive tract resulted in studies on a possible usage of lactic acid bacteria. Last years, several in vitro and in vivo experiments on antagonism of different Lactobacillus strains against Helicobacter pylori and Clostridium difficile were performed. These observations had been done on already established, well known probiotic Lactobacillus strains. We tested antibacterial activities of Lactobacillus strains isolated from human digestive tract. As indicator bacteria, four species known as anaerobic bacterial etiologic agents of gastroenteric infections: Helicobacter pylori, Campylobacter jejuni, C. coli and Clostridium difficile were used. Some of them were obtained from international collections, others were clinical isolates from specimens taken from patients with different defined gastrointestinal infections. We used a slab method of testing inhibitory activity described in details previously. Following conclusions were drawn from our study: - All tested human Lactobacillus strains were able to inhibit the growth of all strains of anaerobic human gastrointestinal pathogens used in this study. - Inhibitory activities of tested Lactobacillus strains against Helicobacter pylori, Campylobacter spp., and Clostridium difficile as measured by comparing mean diameters of the inhibition zones were similar. - Differences in susceptibility of individual indicator strains of Campylobacter spp. and Clostridium difficile to inhibitory activity of Lactobacillus strains were small. - A similar mechanism of inhibition of anaerobic bacteria by lactobacilli is postulated.

17

Zaburzenie homeostazy zelaza w limfoblastach L5178Y myszy we wczesnej fazie parakrynnego dzialania tlenku azotu

72%

Lipinski P.

Prace i Materiały Zootechniczne. Monografie i Rozprawy

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2005

|

nr 12

1-90

18

Antagonizowanie środowiska

72%

Bojanowicz J.

Przegląd Techniczny

|

1993

|

nr 05

19

Ochronne dzialanie mikroorganizmow saprofitycznych w warunkach zagrozenia soi przez grzyby przezywajace w glebie

58%

Pastucha A.

Roczniki Akademii Rolniczej w Poznaniu. Ogrodnictwo

|

1998

|

tom 27

207-211

20

Wpływ fenoksybenzaminy i klonidyny na receptor adrenergiczny w mózgu szczura; badania histofluorescencyjne i ultrastrukturalne

58%

Wawrzyniak M. , Cybulska R.

Annales Universitatis Mariae Curie-Skłodowska. Sectio DD:Medicina Veterinaria

|

1985

|

tom 40