Wyniki wyszukiwania - Biblioteka Nauki

1

Pro-inflammatory properties of cadmium

100%

Olszowski T. , Baranowska-Bosiacka I. , Gutowska I. , Chlubek D.

Acta Biochimica Polonica

|

2012

|

tom 59

|

nr 4

475-482

EN

Cadmium is a toxic and carcinogenic heavy metal that nowadays constitutes a serious environmental health problem. The aim of this study is to review the effects of cadmium on selected inflammatory mediators and markers, such as NF-κB and AP-1 transcription factors, IL-6, TNF-α, IL-1β cytokines, IL-8 or MIP-2 chemokine, MPO, iNOS, MMPs and COX-2 enzymes, PGE2 (product of COX-2 enzyme), ICAM-1, VCAM-1 and PECAM-1 adhesion molecules, and CRP. The research strategy identified articles available in Medline, published between 1998 and 2012; we included both in vivo and in vitro studies carried out on humans and rodents. Most of the reviewed research findings suggest that cadmium in micromolar concentrations (especially in the 1-10 μM range) causes up-regulation of the mediators and markers of inflammation, and appears to have pro-inflammatory properties. However, it is worth mentioning that a contradictory or even opposite hypothesis exists, which suggests cadmium to be an anti-inflammatory factor. Further research including detailed histological analyses should solve this discrepancy. Nevertheless, it appears that the main reason for these contradictory findings is the experimental setup: different biological systems analyzed and different doses of cadmium applied.

2

Effect of anthocyanins on selected biochemical parameters in rats exposed to cadmium.

80%

Kowalczyk E. , Kopff A. , Fijałkowski P. , Kopff M. , Niedworok J. , Błaszczyk J. , Kędziora J. , Tyślerowicz P.

Acta Biochimica Polonica

|

2003

|

tom 50

|

nr 2

543-548

EN

Cadmium is a dangerous occupational and environmental toxin. It accumulates in the human organism mainly in liver and kidneys. Cadmium half-life is about 10 years, so the symptoms of cadmium intoxication may occur several years after the exposure. Until now in treating intoxication with this metal chelating compounds have been used, burdened with numerous undesirable symptoms. In our investigations anthocyanins from Aronia melanocarpa were used to reduce the harmful results caused by cadmium. Administering anthocyanins with cadmium chloride resulted in a statistically significant decrease of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activity, concentration of bilirubin and urea in blood serum and decreased cadmium cumulation in liver and kidneys in relation to animals receiving cadmium chloride only.

3

The influence of cadmium exposure on excretion of pyridinoline and deoxypyridinoline in urine

80%

Prokopowicz A. , Ochota P. , Szuła M. , Kurek J. , Sobczak A.

Medycyna Środowiskowa - Environmental Medicine

|

2012

|

tom 15

|

nr 4

17-23

EN

Background: Osteoporosis is a growing health concern across the world. Some epidemiological data suggest that cadmium increases risk for development of osteoporosis and lead to higher rate of fracture incidents even on low environmental exposure level. Material and methods: Cadmium in urine and bone resorption markers – total fraction of the urinary pyridynoline (Pyr) and deoxypyridinoline (DPyr) – were determined in 36 patients, who were examined for toxic effects of cadmium exposure. Additionally calcium in urine was determined. Associations between cadmium exposure and factors related to bone metabolism were estimated and Pyr and DPyr excretion were compared in three groups categorized across cadmium concentrations. Results: In the investigated group there were significant positive correlations between cadmium levels in urine and Pyr and DPyr excretion. None of the other variables correlated significantly with examined bone resorption markers excluding calcium excretion in urine. Excretion of Pyr and DPyr differed significantly between group with the lowest cadmium concentration (<1.2 μg/g creatinine) and group with the highest cadmium concentration (>1.9 μg/g creatinine), where median values of Pyr and DPyr increased by 49.8% and 37.5%, respectively. Conclusion: The results suggest that cadmium increases bone resorption processes and induce osteotoxic effects in environmental exposure level.

PL

Wstęp: Osteoporoza jest rosnącym problemem na świecie. Niektóre badania epidemiologiczne sugerują, że kadm zwiększa ryzyko rozwoju tej choroby i prowadzi do zwiększenia ryzyka złamań kości nawet przy niskim narażeniu środowiskowym. Materiał i metody: Kadm w moczu oraz biomarkery resorpcji kostnej – całkowite frakcje pirydynoliny (Pyr) i dezoksypirydynoliny (DPyr) w moczu – były oznaczane u 36 pacjentów badanych pod kątem toksycznego działania kadmu. Dodatkowo oznaczano zawartość wapnia w moczu. Oszacowano zależności pomiędzy narażeniem na kadm a czynnikami powiązanymi z metabolizmem kości oraz porównano stężenia Pyr oraz DPyr pomiędzy grupami skategoryzowanymi względem stężenia kadmu w moczu. Wyniki: W badanej grupie wykazano statystycznie istotną pozytywną korelację pomiędzy poziomem kadmu w moczu, a ilością wydalanej Pyr i DPyr z moczem. Żadna z innych badanych zmiennych nie korelowała znacząco z markerami resorpcji kości oprócz wydalania wapnia z moczem. Zróżnicowanie wydalania Pyr i DPyr było statystycznie istotne pomiędzy grupami o najniższym (<1.2 μg/g kreatyniny) i najwyższym stężeniu kadmu w moczu (>1.9 μg/g kreatyniny), w której mediany wartości stężeń Pyr i DPyr wzrosły odpowiednio o 49,8% i 37,5%. Wnioski: Wyniki badań sugerują, że kadm wzmaga procesy resorpcji kości i działa osteotoksycznie również w narażeniu środowiskowym.

4

Effect of cadmium on collagen content and solubility in rat bone.

80%

Galicka A. , Brzóska M. M. , Średzińska K. , Gindzienski A.

Acta Biochimica Polonica

|

2004

|

tom 51

|

nr 3

825-829

EN

The toxic action of cadmium in the bone tissue is known, but its mechanisms are still unexplained. We examined whether Cd influences collagen content and its solubility in the femoral bone of three-week-old female rats exposed to 5 or 50 mg Cd/l in drinking water. Non-cross linked collagen was extracted with 0.5 M acetic acid, and two acid-insoluble collagen fractions were extracted with pepsin and 4.0 M guanidine hydrochloride, respectively. SDS/PAGE showed the presence of two collagen types, I and V, in all three extracted fractions. Exposure of rats to Cd for 6 months increased the amount of acid-soluble collagens type I and V and decreased the level of acid-insoluble collagens. The amount of total collagen extracted from the bones of rats exposed to 50 mg Cd/l was reduced by about 14% as compared to control and those intoxicated with 5 mg Cd/l. The solubility of type I bone collagen (determined as the percentage of acetic-soluble fraction of total collagen) was increased 2.9- and 3.0-fold in rats intoxicated with 5 and 50 mg Cd/l, respectively. Similarly, the solubility of type V collagen was increased 2.3- and 2.7-fold, respectively. Our results indicate that Cd treatment affects bone collagen by decreasing its content and increasing its solubility.

5

Selective flotation of zinc (II) and cadmium (II) ions from dilute aqueous solutions in the presences of halides

80%

Ulewicz M. , Walkowiak W. , Kozłowski C.

Physicochemical Problems of Mineral Processing

|

2001

|

tom Vol. 35

21-29

EN

An experimental investigation is presented of the batch ion flotation of zinc(II) and cadmium(II) ions from dilute aqueous solutions with sodium dodecylbenzenesulfonate (DBSNa) as an anionic surfactant and cetylpyridinium chloride (CPCl) as a cationic surfactant. The effect of halides, i.e. fluorides, chlorides, bromides, and iodides, on the selectivity of cadmium(II) over zinc(II) is established. Separation of Cd(II) and Zn(II) ions by DBSNa is not occurred. The separation of Cd(II)/Zn(II) by CPCl in presence of halides at concentration range of 0.001 M to 1.0 M increases in sequence: F- < Cl- < Br- < I-.

PL

Zbadano wydzielanie oraz selektywne rozdzielanie jonów cynku i kadmu w postaci Zn2+ i Cd2+ oraz jako aniony kompleksowe z wybranymi ligandami nieorganicznymi z roztworów wodnych zawierających zarówno pojedyncze metale jak i z roztworów zawierających równomolową mieszaninę obu metali przy użyciu kolektora kationowego - chlorku cetylopirydyniowego (CPCl) oraz kolektora anionowego - dodecylobenzenosulfonianu sodu (DBSNa). Ponieważ cynk i kadm tworzą kationowe formy kompleksowe o podobnych wartościach stałych trwałości rozdzielenie jonów Zn(II) i Cd(II) przy użyciu kolektora anionowego nie jest możliwe. Separacja jonów kadmu(II) od cynku(II) jest natomiast możliwa przy zastosowaniu kolektora kationowego, tj. chlorku cetylopirydyniowego. Separacja badanych jonów metali przy użyciu CPCl w obecności halogenków o stężeniu 0,5 i 1,0 M wzrasta w szeregu: F- < Cl- << Br- < I- . Współczynniki selektywności Cd(II)/Zn(II) dla stężenia ligandów równego 0,5 M wynoszą odpowiednio: 7,3; 59,2; 82,0 i dla stężenia 1,0 M odpowiednio: 6,0; 67,0; 85,0. Tak więc, niezależnie od stężenia halogenków, najlepsze rozdzielenie jonów Cd(II) od Zn(II) uzyskano w obecności jonów jodkowych i bromkowych w roztworze wodnym.

6

Investigation and elimination of surfactant-induced interferences in anodic stripping voltammetry for the determination of trace amounts of cadmium

80%

Grabarczyk M. , Wardak C. , Wawruch A.

Physicochemical Problems of Mineral Processing

|

2023

|

tom Vol. 59, iss. 4

art. no. 170717

EN

This article aims to investigate in detail to what extent surfactants affect the determination of cadmium by anodic stripping voltammetry. In recent years, the production and use of surfactants have been steadily increasing, so that their concentration in environmental water samples is rising. At the same time, it is known that organic compounds, such as surfactants, often hinder the voltammetric determination of trace elements by stripping. Non-ionic (Triton X-100, Brij 35, Tween 20, Tween 60, Tween 80), cationic (CTAB, CTAC, DTAB, HPC) and anionic (DSS, SDS) compounds were selected to investigate the effect of surfactants on the voltammetric signal of cadmium. At the same time, the extent to which the addition of Amberlite resins to the analysed solution eliminates the interfering effect of surfactants was tested. Three types of Amberlite resins XAD-2, XAD-7 and XAD-16 were selected for the study and the ratio of resin weight to solution volume was determined. Finally, the determination of cadmium in surfactant-enriched environmental samples was carried out. The recoveries obtained between 95.5 and 107%, with RSD between 3.4 and 6.2%, confirm the validity and correctness of the proposed procedure All measurements were carried out by anodic stripping voltammetry using a CNTs/SGC electrode modified with a bismuth film as the working electrode.

7

Elektrokinetyczne usuwanie kadmu z gleby w warunkach zmiennej wilgotności

80%

Zieliński S. , Sikorska-Sobieraj E.

Przemysł Chemiczny

|

2003

|

tom T. 82, nr 8-9

1069-1071

8

Effects of Bio Product on Rice Growth, Rice Yield and Decreases in Cadmium Contents in Soil and Rice Grains

80%

Sitisara W. , Pongpattanasiri S.

Journal of Ecological Engineering

|

2022

|

tom Vol. 23, nr 4

105--109

EN

The aim of this research was to study the effects of chemical (CH) and bioproduct (MIC) fertilizers on rice growth (plant height), rice yield (full grains), and the decrease in cadmium (Cd) contents in soil and rice grains. A silty clay loam (SCL) soil for growing rice was prepared in the laboratory, with Cd addition and pH control. The relationship between CH and MIC fertilizer additions in various amounts with the reduction in the Cd contents of soil and rice grains was explored. As a result, the rice growth in the harvest phase and the yield increased from 138.80 ± 5.72 to 888.40 ± 2.38 cm⋅plant-1 and 689 to 888 seeds⋅plant-1, respectively, when the bioproduct was increased from MIC100 (0.625 L⋅ha-1) to MIC500 (3.125 L⋅ha-1). The Cd content in the soil during the harvest phase, 35.53 mg⋅kg-1, which was less than the standard value of 37.00 mg⋅kg-1 defined by the Pollution Control Department (PCD), Thailand, decreased when the bioproduct increased to MIC500. For the Cd contents in polished rice grains, when MIC500 was added, 0.19 mg⋅kg-1 of Cd was accumulated, which is acceptable according to the Codex Committee on Food Additives and Contaminants (CCFAC) threshold of 0.20 mg⋅kg-1 for Cd. Thus, MIC500 was the most effective in reducing the Cd accumulation in soil and rice grains and promoting rice growth among all MIC amounts.

9

The Elimination of Cadmium(II) from Aqueous Environment by Supported Liquid Membrane Method Using the Basic Carrier

80%

Ashraf M. W. , Bukhari A.

Polish Journal of Chemistry

|

2009

|

tom Vol. 83, nr 1

19-30

EN

The transport of cadmium ions through a supported liquid membrane containing triethanolamine (TEA) as a mobile carrier has been studied. The effects of Cd(II) concentration, HCl in feed and car rier con cen tra tion in mem brane have been stud ied. Cd(II) con - cen tra tion in crease in feed leads to an increase influx from 2.1´10-7 to 8.4´10-7 mol cm-2 sec-1 within Cd(II) ions concentration range (2.7´10-4 M - 16.3´10-4 M) at 2.0 M HCl in the feed and 3.0 M triethanolamine in the membrane. Increase in H+ ion concentration from 0.5 M to 3.0 M results in an increase in Cd(II) ions flux but a decrease is observed beyond 2.0 M HCl concentration in feed. Increase in carrier concentration in the liquid inside the membrane enhances the flux with its maxima at 3.0 M carrier. Further increase in the concentration of TEA leads to a decrease in transport due to increase in viscosity of membrane liquid. The optimum conditions for Cd(II) ions transport are, 2.0 M HCl in feed, 3.0 M TEA in membrane and 0.1 M NaOH as strip solution. Similar transport characteristics have been observed for Cd-EDTA complexed anions across TEA- cyclo - hexanone based SLM, thus indicating a cadmium anion transport coupled with protons and chloride or EDTA co-ions.

10

The simple isocratic HPLC-UV method for the simultaneous determination of reduced and oxidized glutathione in animal tissue

80%

Begic A. , Djuric A. , Gobeljic B. , Stevanovic I. , Lukic V. , Stanojevic I. , Ninkovic M. , Saso L. , Vojvodic D. , Djukic M.

Acta Chromatographica

|

2017

|

tom Vol. 29, no. 1

67--84

EN

The aim of our work was to optimize and apply simple high-performance liquid chromatography method with ultraviolet detection (HPLC-UV) for simultaneous determination of reduced (GSH) and oxidized (GSSG) glutathione in biological matrix (specifically, the rat liver tissue was used herein), since the ratio between oxidized and reduced glutathione forms (GSSG-GSH) has been recognized as an important biological marker of oxidatively depleted GSH in oxidative stress (OS)-associated diseases and poisonings. An isocratic chromatographic separation of GSH and GSSG (2.8 min and 6.3 min, respectively) was performed with the mobile phase consisted of sodium perchlorate solution (pH adjusted to 2.8) at flow rate of 1 mL min−1, detection set at 215 nm, and column temperature of 40 °C. The method offers short run time, linearity in the range of 0.01-200 μM concentration for both compounds (R2 = 1), low limits of detection and quantification (GSH: 0.18 μM and 0.56 μM, GSSG: 0.52 μM and 1.58 μM, respectively), precision, accuracy (bias < 2%), and high reproducibility. Through suitable sample handling, an overestimation of GSSG was prevented. High recovery (>99%) was achieved. The method was successfully applied for the analysis of GSH and GSSG in liver homogenates of Wistar rats intraperitoneally exposed to cadmium (Cd) (1 mg kg−1 CdCl2/21 days). Regardless of other Cd-mediated hepatotoxicity mechanisms, herein, we have exclusively interpreted/emphasized oxidative GSH depletion. The presented method is acceptable for a routine analysis of GSH and GSSG in biological matrix, while the calculated ratio GSSG-GSH is considered as a valuable OS marker.

11

ADSORPTION OF CADMIUM IONS ON CHITOSAN MEMBRANES: KINETICS AND EQUILIBRIUM STUDIES

80%

Zielińska K. , Chostenko A. G. , Truszkowski S.

Progress on Chemistry and Application of Chitin and its Derivatives

|

2010

|

tom 15

73 - 78

EN

The presence of toxic heavy metals in industrial wastewater is a serious pollution problem. The ability of chitosan membranes as an adsorbent for cadmium ions in aqueous solution was studied. Experiments were carried out as function of contact time and concentration of cadmium ions. This study has shown that chitosan is capable of removing cadmium from aqueous solution. The removal efficiency depends on reaction time and concentration of cadmium. The Langmuir and Freundlich adsorption models were applied to describe the isotherms and isotherm constants. Equilibrium data agreed very well with the Langmuir model. The maximum adsorption capacity of the Langmuir isotherm equation was 94 mg/g and the Langmuir adsorption equilibrium constant was 1.6 × 10-3 dm3/mg at 25 °C.

12

Overexpression of genes involved in phytochelatin biosynthesis in Escherichia coli: effects on growth, cadmium accumulation and thiol level.

80%

Wawrzyńska A. , Wawrzyński A. , Gaganidze D. , Kopera E. , Piątek K. , Bal W. , Sirko A.

Acta Biochimica Polonica

|

2005

|

tom 52

|

nr 1

109-116

EN

In Escherichia coli, heterologous production of Schizosaccharomyces pombe phytochelatin synthase (PCS) along with overproduction of E. coli serine acetyltransferase (SAT) and γ-glutamylcysteine synthase (γECS) was achieved and resulted in the accumulation of phytochelatins in bacterial cells. Overproduction of either γECS alone or simultaneous production of all three proteins in bacterial cells were accompanied by reduced growth rate in liquid cultures. Interestingly, bacteria overproducing either γECS or both SAT and γECS (with elevated level of γ-glutamylcysteine but not of phytochelatins) were able to accumulate more cadmium per dry weight than the control. However, the most efficient cadmium accumulation was observed in bacteria with elevated levels of all three proteins: SAT, γECS and PCS. Therefore, "pushing" the entire pathway might be the most promising approach in modification of bacteria for potential bioremediation purposes because the level of intermediates, cysteine and glutathione, can limit the rate of production of phytochelatins. However, in such bacteria other metabolic process might become limiting for efficient growth.

13

Removal of Cadmium using Alkaline-Treated Activated Carbon from Leucaena Leucocephala Biomass

80%

Ibrahim W. M. H. W. , Sulaiman N. S. , Amini M. H. M. , Kadir W. R. A. , Mohamed M. , Ramle S. F. M. , Bilgin U. , Rahman W.

Archives of Metallurgy and Materials

|

2022

|

tom Vol. 67, iss. 3

1033--1036

EN

Water contamination that caused by heavy metals is a very common phenomenon in the industrial age. One of the popular way to treat metal contaminated water is by adsorption process using activated carbon as the adsorbent. This paper works on producing activated carbon by chemical means with impregnation ratios of NaOH:char (w/w) was predetermined at 1:1 (ACT1-1), 2:1 (ACT2-1) and 3:1 (ACT3-1) under activation temperature of 700°C. Considering the Leucaena leucocephala is a wildly, easy and fast grown species, with the availability throught the year, it was chosen to be used as the precursor. The properties of these activated carbons and its potential for cadmium removal from aqueus solution was analyzed. It was found that the highest surface area was recorded at 662.76 m²/g. Four parameters were studied which are contact time, the effect of pH, initial concentration of adsorbate and temperature. The equilibrium time was achieved in 40 min treatment at initial concentrations of 30 mg/l. The adsorbent exhibited good sorption potential for cadmium at pH 8.0 and equilibrium temperature of 30℃. Based on the results, this study had proved that activated carbon from Leucaena leucocephala biomass have the good potential to be used for removal of cadmium from wastewater.

14

The toxic Doppelganger: on the ionic and molecular mimicry of cadmium

80%

Chmielowska-Bąk J. , Izbiańska K. , Deckert J.

Acta Biochimica Polonica

|

2013

|

tom 60

|

nr 3

369-374

EN

Cadmium is a toxic heavy metal which can cause numerous alterations in cell functioning. Exposure to cadmium leads to generation of reactive oxygen species, disorders in membrane structure and functioning, inhibition of respiration, disturbances in ion homeostasis, perturbations in cell division, and initiation of apoptosis and necrosis. This heavy metal is considered a carcinogen by the Agency for Toxic Substances and Disease Registry. At least some of the described toxic effects could result from the ability of cadmium to mimic other divalent ions and alert signal transduction networks. This review describes the role of cadmium mimicry in its uptake, reactive oxygen species generation, alterations in calmodulin, Wnt/β-catenin and estrogen signaling pathways, and modulation of neurotransmission. The last section is dedicated to the single known case of a favorable function performed by cadmium mimicry: marine diatoms, which live in zinc deficient conditions, utilize cadmium as a cofactor in carbonic anhydrase - so far the only described cadmium enzyme.

15

Temporal and spatial changes of cadmium in the near-bottom suspended matter of the Pomeranian Bay - Arkona Deep system

80%

Staniszewski A. , Pazdro K. , Bełdowski J. , Leipe T. , Emeis K. C. , Pempkowiak J.

Oceanologia

|

2000

|

tom No. 42 (4)

483-491

EN

Owing to the high toxicity of cadmium (Cd) towards biota and the considerable quantities of this element entering the environment from anthropogenic sources, interest in its biogeochemistry is increasing. This is also true for the marine environment, which serves as a sink for both natural and anthropogenic Cd loads entering the hydrosphere and the atmosphere. The distribution of Cd in the coastal zone of the marine environment is governed primarily by the flux of the so-called fluffy layer suspended matter (FLSM), which spreads across the top of the sea floor as a several-centimetre-thick layer containing highly concentrated suspended matter. Both total contents and solid speciation of Cd was measured in FLSM collected in the Pomeranian Bay - Arkona Deep system (Western Baltic Proper) in the course of the three-year-long study. Seasonal changes in the total Cd content (0.5-1.8 žg g–1 dry matter) were attributed to the contribution of organic suspensions originating from algal blooms. The decreasing content of Cd in FLSM offshore is due to the input of Cd-rich suspended matter from the River Odra (Oder), and the decreasing organic matter content in FLSM with increasing depth. The contribution of labile fractions (adsorbed and bound to iron III hydroxides) was found to be from 50 to 75% of the total content. In view of the substantial mobility and bioavailability of the fractions, this is a highly alarming feature.

16

Chromatographic properties of the cadmium induced SOD isoform in Rhizopogon roseolus

80%

Miszalski Z. , Niewiadomska E. , Skoczowski A. , Botton B.

Acta Physiologiae Plantarum

|

1998

|

tom 20

|

nr 3

EN

Exposure of Rhizopogon roseolus mycelia to 15 mmol·dm⁻³ cadmium for 24 h induces a different pattern of Mn-SOD on polyacrylamide gels, probably being a changed form of an originally existing one. The presence of cadmium affects the chromatographic properties of this enzyme and its mobility through the acrylamide gel. This new isoform was purified using DEAE Trisacryl chromatography. Cadmium induced isoform adsorbed stronger to the ligands and was eluated with a Tris-HCl buffer containing 0.1 mol·dm⁻³ NaCl. SOD from control samples (not treated with cadmium) was eluated with the same buffer without NaCl.

17

Spectrophotometric determination of cadmium [II] in soil of allotment gardens in Lodz

80%

Jankiewicz B. , Ptaszynski B. , Wieczorek M.

Polish Journal of Environmental Studies

|

2000

|

tom 09

|

nr 2

EN

Cadmium was determined in the soil of six allotment gardens of Lodz, situated in areas with different traffic patters (the centre of the city and its suburbs). It was determined in the form of cadmium (II) dithizonate by the extraction-spectrophotometric method.

18

The role of vacuolar digestive system in preventing cadmium poisoning in Acanthamoeba castellanii

80%

Przelecka A. , Kluska A. M. , Zwierzyk M.

Folia Histochemica et Cytobiologica

|

1993

|

tom 31

|

nr 2

19

Effect of Cd2 on phosphate exchange in Staphylococcus aureus

80%

Tynecka Z. , Malm A.

Acta Biochimica Polonica

|

1992

|

tom 39

|

nr 1

20

Influence of cadmium and lead partitioning in water and sediment on their deposition in the sediment of a eutrophic dam reservoir

70%

Szarek-Gwiazda E. , Mazurkiewicz-Boroń G.

Oceanological and Hydrobiological Studies

|

2006

|

tom Vol. 35, No.2

141-157

EN

This study was conducted in the submontane and eutrophic Dobczyce Reservoir (southern Poland). Cadmium and lead concentrations in the water and sediment were relatively low. The partitioning coefficient (Kd) indicated that dissolved Cd and Pb dominated in the water column at depths of 1 and 15 m, and that they were present in the particulate phase in near-bottom water. The relation of dissolved Cd and Pb with physical and chemical parameters of the water is discussed. Binding forms of Cd and Pb in the sediment showed that Cd was potentially a more “mobile’ element than Pb; therefore, Cd had probably accumulated in the sediment in considerably lower amounts than Pb (K=8400 and K=33000, respectively).