Wyniki wyszukiwania - Biblioteka Nauki

1

Pharmacological profile and mechanism of action of antidepressant drugs

100%

Maj J.

Acta Physiologica Polonica

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1987

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tom 38

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nr 4

2

Strengthening the rough selection effect of n-ethyl o-isopropyl thionocarbamate (Dow: Z-200) on chalcopyrite by ultrasonic pretreatment

100%

Wang Y. , Wang Y. , Yu B. , Wang X. , Ma X.

Physicochemical Problems of Mineral Processing

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2021

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tom Vol. 57, iss. 1

64--74

EN

In this study, the properties of (CH3)2CHOC(S)NHC2H5(Dow: Z-200) after the ultrasonic pretreatment was characterized by employing surface tension, viscosity, and Fourier transform infrared (FTIR) spectroscopy, and its influence on chalcopyrite rough selecting was investigated. The results indicate that the pretreated Z-200 can improve the index of chalcopyrite roughing. And, under the same reagent system, the recovery of copper reached 82.84% which was an increase of 24.44% compared with the untreated when Z-200 after ultrasonic pretreatment was applied to the rough separation of chalcopyrite. The reason why ultrasonic can strengthen the flotation effect of Z-200 on chalcopyrite is that ultrasonic pretreatment can decrease the surface tension and viscosity of Z-200 and enhance its foaming performance. Meanwhile, the ultrasonic cavitation destroys the molecular structure of Z-200, so that the relative proportion of methyl absorption peak and amine absorption peak in Z-200 increases. This also further improves the collection performance and foaming performance of Z-200 and strengthens its separation effect on chalcopyrite. The research provides a new idea for Z-200 to act on chalcopyrite and improve its flotation efficiency, reduce the amount of flotation reagent, and its pollution to the environment. It also provides a theoretical basis for expanding the application of ultrasonic technology in the field of flotation.

3

The effect of Al(III) and Fe(III) ions on the flotation behavior of Kfeldspar with sodium oleate as the collector

88%

Chen Y. , Zhou J. , He G. , Hu H. , Liu C. , Yang J. , Lyu X.

Physicochemical Problems of Mineral Processing

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2023

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tom Vol. 59, iss. 6

art. no. 174724

EN

The present study investigates the effects and mechanisms of aluminum (Al(III)) and iron (Fe(III)) ions on the flotation efficiency of potassium feldspar (K-feldspar) within oleate collector systems. The study employs micro-flotation experiments, solution chemistry calculations, zeta potential measurements, and FT-IR and XPS analyses to demonstrate that Al(III) and Fe(III) ions can significantly improve the flotation recovery of K-feldspar by altering its surface charge, bonding properties, and adsorption modes. The study also develops adsorption models for the flotation of K-feldspar activated by Al(III) and Fe(III), revealing the synergistic impacts of metal ion hydrolysis products and sodium oleate in the formation of hydrophobic complexes.

4

Dynamin: characteristics, mechanism of action and function

63%

Wiejak J. , Wyroba E.

Cellular and Molecular Biology Letters

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2002

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tom 07

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nr 4

EN

Dynamin - a member of the GTP-ase protein family - is essential for many intracellular membrane trafficking events in multiple endocytic processes. The unique biochemical features of dynamin - especially its propensity to assemble - enable severing the nascent vesicles from the membrane. The mechanism of dynamin’s action is still a subject of debate - whether it functions as a mechanochemical enzyme or a regulatory GTPase. The GTPase domain of dynamin contains three GTP-binding motifs. This domain is very conservative across the species, including that recently cloned by us in the unicellular eukaryote Paramecium. Dynamin interacts with a number of partners such as endophilin and proteins involved in coordination of endocytosis with motor molecules. A growing body of evidence indicates that dynamin and dynamin-related proteins are involved both in pathology and protection against human diseases. The most interesting are dynamin-like Mx proteins exhibiting antiviral activity.

5

Anchoring principles of a new energy-absorbing expandable rock bolt

63%

Wen Z. , Jiang Y. , Han Z. , Yang S. , Wang X.

Engineering Transactions

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2016

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tom Vol. 64, iss. 1

89--103

EN

The greater the mine, the harder stability control will be. And the conventional rock bolts do not adapt well to the severe rock stress conditions. An ideal bolt having a high resistance and large deformation should be developed. Based on the test results and theoretical study, this paper proposes an energy-absorbing expandable rock bolt, which consists of the bar, sleeve, bolt plate, nut, and bolt end. The anchoring mechanism and its efficiency were systematically analysed in the laboratory and in practice: the anchoring mechanism and supporting density, especially the quantitative relationship, were deduced under the Energy Balance Theory, that is, EB = 1 2 · n · F0 (u0 + 2∆u). As Compared with the conventional bolt and large deformation bolts, the new type of bolt could provide a larger constant resistance, even in the soft rock roadway with large squeezing deformation, the pulling force can be achieved by F = A · σ · f2, it mainly being generated by a normal stress acting on the pore surface. These characteristics are helpful in making the supported roadway safe. The amount of released energy during the large deforming process of the surrounding rock is expressed through conservation of energy, which can provide reference to the quantitative calculation of the bolt supporting system.

6

Glukozynolany w profilaktyce chorob nowotworowych - mechanizmy dzialania

63%

Kwiatkowska E. , Bawa S.

Roczniki Państwowego Zakładu Higieny

|

2007

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tom 58

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nr 1

7-13

PL

Żywność pochodzenia roślinnego oprócz odżywczych składników zawiera również wiele cennych składników nieodżywczych, które mogą działać profilaktycznie oraz leczniczo w różnych chorobach cywilizacyjnych, między innymi w nowotworach. Rośliny produkują tysiące związków fenolowych jako drugorzędne metabolity, między innymi związki azotowe. Glukozynolanom przypisuje się rolę wspomagającą syntezę enzymów odtruwających, odpowiedzialnych za szybkie wydalanie z organizmu substancji rakotwórczych. Po za tym stwierdzono, że aktywują białka i enzymy fazy drugiej detoksykacji. Związki te są bardzo ważne z punktu widzenia żywieniowego i dlatego cały czas prowadzone są badania nad ich pozytywnym wpływem w walce z nowotworami.

EN

Foods of plant origin, despite plenty of nutrients contain many non-nutrition compounds, which may prevent many diet-related non-communicable diseases, such as cancer. Plants produce thousands of phenolic compounds as secondary metabolites, such as nitrous compounds. Glucosinolates are responsible for the secretion of detoxifying enzymes that remove carcinogens for the organism. Furthermore, they activate proteins and II phase detoxifying enzymes. The compounds are very important that is why scientists are still investigating their beneficial note in cancer prevention and management.

7

Poglądy na mechanizm działania nowoczesnych środków owadobójczych

63%

Mlodecki H.

Roczniki Państwowego Zakładu Higieny

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1959

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tom 10

|

nr 3

8

Powłoki pęczniejące do przeciwogniowego zabezpieczania konstrukcji stalowych

51%

Zubielewicz M.

Ochrona przed Korozją

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2009

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tom nr 6

234-237

PL

Do zabezpieczania konstrukcji stalowych przed działaniem ognia stosuje się głównie powłoki pęczniejące. Tego typu powłoki tworzą pod wpływem wysokich temperatur spęcznioną warstwę izolacyjną, która spowalniając nagrzewanie się stali do temperatury krytycznej zapobiega zawaleniu się konstrukcji i umożliwia ewakuację ludzi ze strefy zagrożenia. Omówiono skład, mechanizm działania, metody badań oraz trwałość powłok pęczniejących w warunkach wilgotnych.

EN

Intumescent coatings are used mainly for fire protection of steel structures. Intumescent coatings swell when exposed to fire, forming thick layer of char around the steel and insulating it from the heat. This insulating layer slows down a heating of steel structures to the temperature at which they lose structural integrity and collapse and thus enables an evacuation of people from danger zone. The composition, mechanism, test methods and durability of intumescent coatings in wet conditions have been discussed.

9

Antybiotykoterapia u świń cz.5. Charakterystyka fluorochinolonów

51%

Pomorska-Mol M.

Lecznica Dużych Zwierząt. Ogólnopolski Kwartalnik dla Lekarzy Weterynarii

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2015

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tom 10

|

nr 3

10

Wykorzystanie akupunktury w medycynie weterynaryjnej

51%

Pryszcz M. , Likus M. , Aleksiewicz R.

Weterynaria w Praktyce

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2020

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tom 17

|

nr 06

11

Tebufenozyd [Tebufenozide] - agonista Ekdyzonu jako insektycyd w ochronie lasu

51%

Malinowski H. , Glowacka B.

Progress in Plant Protection

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1996

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tom 36

|

nr 1

222-228

12

Peroksydazy - małe enzymy o wielkim znaczeniu

51%

Pawlowska A. , Treder K.

Ziemniak Polski

|

2014

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tom 24

|

nr 1

13

Środki iniekcyjne do wykonywania wtórnych izolacji poziomych w murze

51%

Monczyński B. , Ksit B.

Materiały Budowlane

|

2017

|

tom nr 3

10--13

14

Perspektywy i ograniczenia wykorzystania bioinsektycydow w rolnictwie ekologicznym

51%

Kuhne S.

Progress in Plant Protection

|

2008

|

tom 48

|

nr 4

1309-1313

15

Zmiany ladunku elektrostatycznego a wzrost nowotworow

51%

Jaskowski J.

Acta Biologica et Medica

|

1992

|

tom 18

137-153

16

Leczenie przewleklego czynnego zapalenia watroby HBV

51%

Zielinska W.

Acta Biologica et Medica

|

1993

|

tom 20

9-22

17

Jak dzialaja fungicydy? O czym warto pamietac przy wyborze preparatu

51%

Lawecki T. , Janczak C.

Agrochemia

|

1998

|

nr 05

8-11

18

Problem kompensacji chwastow i ich odpornosci na herbicydy

51%

Urbanowicz J.

Ziemniak Polski

|

2009

|

tom 19

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nr 3

32-35

19

Mechanizm nefrotoksycznego dzialania wybranych metali ciezkich

51%

Marchewka Z.

Bromatologia i Chemia Toksykologiczna

|

2009

|

tom 42

|

nr 4

1135-1143

20

Xenoestrogens: mechanisms of action and some detection studies

51%

Slomczynska M.

Polish Journal of Veterinary Sciences

|

2008

|

tom 11

|

nr 3

263-269

EN

Xenoestrogens are defined as chemicals that mimic some structural parts of the physiological estrogen compounds, therefore may act as estrogens or could interfere with the actions of endogenous estrogens. Two subtypes of the ER are known, the ERcc and ER ß, and both have a distinct tissue distribution and play a distinct role in physiology. Receptor dimmer assumes a distinctive conformation, binds to its estrogen response element (ERE), interacts with the general transcription complex bound to the TATA box within the respective gene promoter, and regulates gene transcription. The discovery and identification of co-activators and co-repressors provided crucial insights into the ER action. New evidence indicates that the activation of additional transcription factors as well as the action of xenoestrogens through estrogen receptors located outside the cell nucleus (in the plasma membrane, mitochondria and probably the cytosol) should be considered. The levels of exposition to xenoestrogens and the age of the investigated animal can have a significant effect on its development and reproduction. Therefore, several in vivo and in vitro assays have been developed to assess the estrogenic-like activity of individual compounds or natural mixtures. In this review, selected methods applied in physiological studies have been described. One of the most extensively used in vivo assays for estrogenicity is the rodent uterotrophic assay. In order to analyze the estrogenic properties of xenoestrogens, morphological, histological, biochemical and molecular studies should be introduced. A variety of in vitro tests have been established to determine estrogenic potency of xenoestrogens but even a combination of them is not able to predict their actual action in the organism. There is a need for the studies on all potential xenoestrogens to describe tissue-specific activities, and via which pathways in those tissues these compounds either disrupt or mimic hormone action.