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1
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EN
Introduction: Due to the contemporary fashion for a slim silhouette some women may be concerned about change in their outer appearance during pregnancy. Purpose: To examine the sense of own physical attractiveness among women in advanced pregnancy and its conditioning. Material and methods: From the 1730 who reported for regular health check-up to 3 randomly selected outpatient departments, 260 were selected who became pregnant, and the examinations with the questionnaire were repeated.Results: Before pregnancy 2.3% women were satisfied with their body image, 13.1% – satisfied, 29.2% – unsatisfied, whereas the reminder (55.4%) admitted that they were not able to evaluate it. During pregnancy, the results were as follows: 24.6%, 32.3%, 17.7% and 25.4%, respectively. The differences in the frequency of these replies (prior to and during pregnancy) were highly significant statistically (p<0.001), to the benefit of the pregnant women who were more often satisfied with their body image than those non-pregnant and less often dissatisfied. In the group of women in the study, the level of satisfaction with own physical appearance before pregnancy significantly differed by age (p< 0.05). In advanced pregnancy, age, woman’s general wellbeing in pregnancy, and attitude of the partner towards the pregnant woman were significant (p < 0.05). Conclusions: The sense of own attractiveness among women in advanced pregnancy is varied; nevertheless, it is higher, compared to the period before becoming pregnant. The factors which condition the sense of own attractiveness among women in advanced pregnancy is age, general wellbeing during that time, and the attitude of the partner towards them.
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Content available remote Changes of platelets’ function in preeclampsia
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EN
Increased aggregation of platelets during preeclampsia was shown in several studies, yet several others reported no change. The aim of our study was to investigate platelet aggregation in a group of patients suffering from preeclampsia. In a cross-sectional study blood samples were taken from 89 hospitalized patients in the third trimester of pregnancy: 38 were suffering from mild to moderate preeclampsia and 51 patients were without preeclampsia. From the blood samples platelet aggregation, secretion of adenine nucleotides from platelets, concentration of energy-rich adenine compounds and levels of cyclic adenosine-mono-phosphate and cyclic guanosine mono-phosphate in platelets were measured. In the patients with preeclampsia, the adenosine diphosphate threshold for biphasic aggregation [odds ratio (OR):.75; 95% Confidence Interval (CI): 0.55–1.02; p<0.05], total adenine nucleotides concentration in the metabolic pool of platelets (OR:0.99; CI: 0.62–1.57; p<0.01) and cyclic adenosine-mono-phosphate (OR:0.81; CI: 0.57, 1.14; p<0.05) and cyclic guanosine mono-phosphate (OR:.78; CI: 0.55–1.09; p<0.05) levels in platelets were decreased in comparison with the control group, while adenylate energy charge in the metabolic pool of platelets (OR: >100.00; CI: 0.00->100.00; p<0.05) and secretion of adenosine triphosphate (OR:.13; CI: 0.00–14.26; p<0.05) and adenosine diphosphate (OR:.77; CI: 0.08–36.79; p<0.05) were increased. The results of our study show increased activation and aggregation of platelets in pregnant females with preeclampsia.
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Content available remote Venous thromboembolism in pregnant woman - a challenge for the clinician
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EN
Deep vein thrombosis and pulmonary embolism are two clinical entities of a single disease called venous thromboembolism. Venous thromboembolism is an important cause of maternal morbidity and mortality. Diagnosis and treatment of venous thromboembolism in pregnant women are much more difficult than in non-pregnant women. Pregnant patients were excluded from all major clinical trials investigating therapeutic combinations for acute thromboembolism. Although, for many years, the standard anticoagulant during pregnancy and postpartum was unfractionated heparin, current guidelines recommend low molecular weight heparin. The advantages of low molecular weight heparin are lower risk of bleeding, predictable pharmacokinetics, lower risk of fracture because of thrombocytopenia and heparin-induced osteoporosis.
EN
Introduction: In the Czech Republic, screening of glucose tolerance disorders is performed in all pregnant women in two stages: measuring glycaemia in a fasting patient within 14 weeks of pregnancy, and between the 24th and 28th weeks by performing an oral glucose tolerance test (oGTT). Goal: To determine how the oGTT is performed from the point of view of pregnant women. Materials and Methods: A total of 134 women in their 35th–44th week of pregnancy completed a non-standardized questionnaire. The research was carried out at workplaces in Zlín. Results: Only three respondents knew how many grams of glucose are drunk for an oGTT and one stated that it is necessary to fast for 8 hours before an oGTT. Capillary blood was taken in 22 cases, which is unacceptable in relation to recommendations. Conclusions: Inadequate knowledge concerning the preparation and performance of the oGTT may lead to distorted laboratory results.
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Content available remote Takotsubo cardiomyopathy in pregnancy
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EN
We have described a rare case of Takotsubo cardiomyopathy in pregnancy, which is presented with cardiac arrest (ventricular fibrillation) at onset. In this case, the transient left ventricular ballooning in absence of coronary artery disease, produced a severe impairment of cardiac function with typical echocardiographic and electrocardiographic findings. There were complications in the form of ventricular fibrillation, with recurrence due to possible Takotsubo cardiomyopathy and new malignant heart rhythm disorder that increases the mortality rate compared with the first attack of Takotsubo cardiomyopathy. Due to presented symptoms the patient has opted for the implantation of cardioverter defibrillator.
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Content available remote Cushing’s syndrome diagnosed after delivery: a case report
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Content available remote Prenatally diagnosed fetal omphalocele at 11 week gestation - a case report
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EN
Omphalocele is the most common congenital defect of the abdominal wall and in a large percentage of cases it is associated with chromosomal anomalies. In this case report during the regular ultrasound examination at 11 weeks of gestation, omphalocela, whose scope was 90% of fetal abdomen, was diagnosed. Karyotype analysis showed the presence of chromosomal aberrations 47 XX + 18 (Edwards syndrome). After the presentation of the severity of congenital anomalies and characteristic of the Edwards syndrome patient decided to terminate the pregnancy.
EN
The aim of this study was to analyse perinatal complications in woman with increased BMI at pregnancy term. Study included 23190 women who gave singleton birth during a 10-year period in our institution. Maternal databases were reviewed for pregnancy, labor and delivery complications and early maternal postpartum morbidity. Women with increased BMI at pregnancy term had a significantly higer incidence of postterm pregnancy, gestational diabetes, pregnancy-induced hypertension and third trimester hemorrhage, compared to normal weight women (p 0.000). Women with increased BMI had significantly more labor induction with prostaglandins (p 0.001 and 0.000) and elective caesarean (p 0.025 and 0.000). Also, overweight and obese women had higher incidence of operative delivery: caesarean section (p 0.000) and vacuum extraction (p 0.000). The incidences of postpartum febrility (p 0.057, 0.000, 0.002) and trombophlebits (p 0.013) were also significantly higher. We can conclude that prepregnancy normal weight women with increased BMI during pregnancy need special follow-up and counseling in pregnancy and delivery.
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Content available remote Gross pericardial effusion with tamponade in 2nd trimester of pregnancy
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EN
Hypothyroidism in pregnancy is associated with serious maternal and fetal risk. Rarely, it is manifested by life-threatening cardiac complications, such as gross pericardial effusion and tamponade. We present a case of successfully treated gross pericardial effusion and tamponade in a 22-week pregnant woman with hypothyroidism. The patient was treated by pericardial drainage with further treatment of hypothyroidism with levothyroxine. During the follow-up pregnancy was uncomplicated without recurrence of pericardial effusion and successful delivery of full-term baby. We conclude that careful monitoring of thyroid functional tests and proper management should be performed in pregnant women with hypothyroidism to prevent cardiac complications of the disease, like pericardial effusion and tamponade.
EN
Pregnancy is a biographically episodic time when the belly becomes the centre of thefeminine world. This time is characterized by the ambivalence of attitudes and moodswhich are not only hormonally-based but result from the very act of experiencing bodilytransition and duplicating subjectivity, which leads to perturbations connected with thedistinction between the me-body and the me-mothering body (Lewis 2013). In this articlewe analyse selected narrations by women about their bodies, pregnancy, childbirth andmaternity. We focus the analytical process on the somatic motif of the belly, which constitutesthe symbolic centre of perception of a woman’s own body during this time, its transformationsand social interactions dominating the world of the woman expecting a baby.
PL
Pregnancy is a biographically episodic time when the belly becomes the centre of thefeminine world. This time is characterized by the ambivalence of attitudes and moodswhich are not only hormonally-based but result from the very act of experiencing bodilytransition and duplicating subjectivity, which leads to perturbations connected with thedistinction between the me-body and the me-mothering body (Lewis 2013). In this articlewe analyse selected narrations by women about their bodies, pregnancy, childbirth andmaternity. We focus the analytical process on the somatic motif of the belly, which constitutesthe symbolic centre of perception of a woman’s own body during this time, its transformationsand social interactions dominating the world of the woman expecting a baby.
EN
Human chorionic gonadotropin (HCG) is used parenterally for treatment of threatened abortions and repeated spontaneous abortion in pregnant women. No controlled epidemiological studies of preterm birth and low birthweight newborns in pregnant women with HCG treatment have been published while the results of animal investigations were controversial. The data of 97 pregnant women with HCG treatment in the second and third months of pregnancy due to threatened abortion and/or previous spontaneous abortion(s) was compared with the data of other 38,054 pregnant women in the population-based large data set of the Hungarian Case-Control Surveillance of Congenital Abnormalities. There was no difference in mean gestational age at delivery and birth weight, in addition the rate of preterm birth and low birthweight newborns. Parenteral HCG treatment in the early pregnancy due to threatened abortion did not associate with a higher risk for preterm births or low birthweight newborns. However, a higher occurrence of gestational diabetes was found in pregnant women with HCG treatment and there was a slight male excess among newborn infants (p=0.06).
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Content available remote Influence of cadmium and copper on tissue element levels of pregnant rats
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In the current study, we examined the effects of Cd on Cd, Cu, Zn and Fe levels in placenta and maternal and fetal plasma and tissues, the placental weight, total fetal and maternal body weights, and fetal and maternal tissue weights during pregnancy. A total of 21 adult female rats were treated during gestation with drinking water containing one of the following: 70 mg/L of CdCl2, a combination of 70 mg/L of CdCl2 and 70 mg/L of CuSO4, or no addition (control). Placenta Cu and Fe levels, fetal liver and kidney Cu levels, and fetal liver tissue weights were lower in the group administered Cd than in the control group. Also, Cd levels in the placenta, maternal and fetal liver, and maternal kidney were higher in the group treated with Cd than in controls. In the group administered both Cd and Cu, fetal body and tissue weights did not change, but Cd levels in the placenta, maternal and fetal liver, and maternal kidneys were higher than in controls. Zn and Fe levels in the maternal kidney and fetal liver were also lower in this group. Cd exposure during pregnancy resulted in Cd accumulation in maternal and fetal tissues during pregnancy and a decrease in the total weight of fetuses, and the combination of Cd and Cu caused some changes in the both maternal and fetal levels of Cu, Zn, and Fe, but it did not cause changes in the total fetal body weight or the weights of individual tissues.
EN
The aim was to identify and quantify the association between the use of particular medications during the first trimester of pregnancy and selected congenital abnormalities (CAs) of newborns. Data were from the Czech National Registry of CAs. We used a case-control design, and collected total of 7285 cases and 9143 controls. Thiethylperazine and iron compounds had no effect on development of CAs. Lower odds ratio and potentially protective associations were found between CAs and bioflavonoids, folic acid, progesterone, levothyroxine, and iodine therapy. Since the protective effect of bioflavonoids was not described before, analysis of interaction with other drugs was performed. However, their protective effect was not confirmed and the strongest significant protective effect was detected in combination of bioflavonoids and progesterone. Increased odds ratio were identified for hydroxyprogesterone, phenoxymethylpenicillin, aspirin, paracetamol and valproic acid. The association between paracetamol and congenital foot deformities was not significant, while the same association for the whole group of CAs and deformities of musculoskeletal system had significantly increased odds ratio. Except newly described effect of bioflavonoids, our results are in agreement with risk categories defined by health authorities in USA and Australia, and with results of other studies. According to our results, paracetamol does not influence development of congenital foot deformities.
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Introduction: Ulcerative colitis is one of the most interesting nosological entities of gastroenterology and internal medicine. This chronic autoimmune disorder of the digestive system, along with Crohn's disease, is a type of idiopathic inflammatory bowel disease. It mainly affects people during their peak reproductive age, i.e., 15 to 30 years old. It is characterized by diffuse mucosal inflammation of the large intestine, which is limited to the colon and shows alternating periods of exacerbations and remissions. Purpose: To review the world literature regarding the impact of the disease on fertility, the course of pregnancy, and consecutively, the outcome of pregnancy.Materials and methods: An extensive review of the recent national and international literature in electronic databases (Pubmed, Google Scholar) and in scientific journals was accomplished through the use of appropriate keywords. Results: The majority of women will have a chance of conceiving. For about 25% of them, conception will be achieved in the course of the disease and it will progress normally, resulting in a healthy fetal outcome. Infertility only occurs among men while they are taking medicines, whereas among women it occurs after surgery for ileoanal anastomosis. During periods of flare-ups, there is a possibility of spontaneous abortion, premature labor and birth of an infant with low birth weight. The majority of pharmaceutical formulations can be used safely both before and after pregnancy without causing any birth defects.
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Content available remote The use of mass spectrometry in obstetric and gynecology
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EN
The present review shows the utility of using mass spectrometry (MS) in obstetrics and gynecology. In this review different gas chromatography / mass spectrometry and liquid chromatography / mass spectrometry methods developed before to be used in obstetrics and gynecology are described. These methods are very useful to determine different hormones in pregnancy, fatty acids esters (related to the use of ethanol) in human meconium and toxic compounds in umbilical cord (as ethanol, steroids, morphine, cocaine, methadone and other drugs). It is also shown in this review the progress during last decades in the field of using mass spectrometry in obstetrics and gynecology (for screening in utero exposure of the child to alcohol, drugs and other toxic compounds). In the field of using mass spectrometry in obstetrics and gynecology are still many problems to solve. For example, the detection of fatty acids esters in meconium has several limitations, which affects the results. One limitation is multiple births. Also in fetal distress, meconium may be passed before birth, and in this case, the collection is impossible. Moreover the meconium is formed starting from the fourth month of pregnancy, so the fetal exposure at any toxic compounds during the first three months cannot be detected at all. To solve all of these, the best would be to combine the results obtained from meconium, with other results obtained from pregnancy serum, placenta or umbilical cord. The main reason for using MS in obstetrics and gynecology is that MS is a noninvasive and a complementary method. It offers the results at a very early point in time, even before the act of birth. Sometimes the use of mass spectrometry is the only alternative. This shows that these methods are of great interest for the future and need to be developed further. [...]
EN
In this paper, we apply the concept of timing to explore the meaning that women attach towards planned and unplanned pregnancy. We conducted qualitative semi-structured interviews with 42 Canadian women who were pregnant or recently gave birth to examine how they experience the transition to motherhood. We contend that the timing of pregnancy is a socially constructed norm that impacts women through a complex range of life events and circumstances. Participants’ accounts suggest a gamut of compliance, ambivalence, and defiance towards the “timing of pregnancy” standards. Situating women’s decisions on childbearing within the continuum of their life trajectories and societal expectations surrounding pregnancy allows for better understanding of the interplay between women’s personal choices and the social norms informing these decisions.
EN
To provide instruction for pregnant women regarding adequate and balanced nutrition and determine whether iron and folic acid supplementation is essential. The research was an experimental clinical intervention. The study was conducted between March 2004 and May 2005 with 80 pregnant volunteers. The study participants were in their 16th to 24th weeks of pregnancy; all participants were healthy, carried only one fetus, and successfully completed their pregnancy. All participants were instructed about adequate and balanced nutrition. Until the participants gave birth, 40 (Group 1) consumed an iron-rich diet that was equivalent to the inclusion of a supplement containing 100 mg Ferro III plus 0,35 mg folic acid; the other group (Group 2) was also instructed in proper nutrition and was given by a gynecologist 1 tablet (100 mg) Ferro III hydroxide polymaltose complex and iron pharmaceutical with 0,35 mg folic acid (Maltofer Fol). In both groups, before and after the instruction, consumption frequency was noted, and the levels of serum ferritin, serum iron, total iron-binding capacity, folic acid, and vitamin B12 in the blood were determined at monthly intervals. Between the two groups, no statistical difference was found with regard to age, number of pregnancies, weight before pregnancy, body mass index (BMI) before pregnancy, and weight of the newborn (p>0,05). At the end of the study, the hemoglobin, hematocrit, and serum ferritin levels decreased considerably in both groups compared to the initial values (p<0.01). No statistically significant difference in serum ferritin levels could be found between the two groups (p>0,05). The comparison of Group I and Group II in terms of nutritional status (average energy and food consumption) in the pre-instruction and post-instruction periods revealed that intake of total protein, heme protein, dietary fiber, folic acid, carotene, vitamins A, B1, B2, B6, C, and B12, potassium, calcium, phosphorus, iron, and zinc was higher in Group I in the post-instruction period (p=0.000); no statistically significant change in nutritional status during pregnancy was observed in Group II. Conclusion: Medical diet programs with iron sources are examined in association with food consumption. Assessment of hematological results suggests that, during pregnancy, each patient should receive a specific dose, rather than a routine dose, of iron and folic acid.
19
Content available Lower-limb ooedema during pregnancy
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PL
Autorzy przedstawili przypadek 30-letniego mężczyzny, u którego doszło do nagłego zatrzymania krążenia w wyniku porażenia prądem wysokiego napięcia. Od 2. tygodnia po wypadku przeprowadzano rehabilitację w warunkach szpitalnych, mającą na celu utrzymanie zakresu ruchomości w stawach oraz od 6. tygodnia przeprowadzano intensywną rehabilitację w warunkach domowych. Mimo przeprowadzanego leczenia zaobserwowano całkowite ograniczenie ruchomości stawów biodrowych oraz w oparciu o radiogram i projekcję przestrzenną TK zdiagnozowano masywne neurogenne skostnienia heterotopowe (NSH). Przeprowadzono dwa zabiegi mające na celu usunięcie NSH: najpierw z okolicy lewego (15. miesiąc od wypadku), a następnie prawego stawu biodrowego (18. miesiąc od wypadku). Po interwencji zaobserwowano istotny wzrost ruchomości obu stawów biodrowych oraz zmniejszenie dolegliwości bólowych, co w efekcie znacznie poprawiło możliwości funkcjonalne pacjenta. Dodatkowo wprowadzono profi laktykę zapobiegającą nawrotom NSH, która polegała na utrzymaniu zarówno biernego, jak i czynnego zakresu ruchu oraz na stosowaniu zabiegów fi zykoterapeutycznych w postaci głębokiej oscylacji. W badaniu TK, wykonanym w 41. miesiącu po wypadku, uwidoczniono NSH w mniejszym stopniu, aniżeli miało to miejsce pierwotnie.
EN
Lower-limb oedemas can be the result of abnormalities in the structure and functioning of the lymphatic system, injuries or inflammation, or can be related to cancer and its treatment; however, they are more often one of the basic symptoms accompanying women in the third trimester of pregnancy due to vein insufficiency. The purpose of this overview is to discuss the current knowledge related to risk factors, prevention and treatment of lower-limb oedemas during pregnancy. The risk factors linked to gravidity-related oedema comprise of increased volume of circulating blood, the augmented uterus, increased body mass and changes to hormonal turnover. Vein insufficiency occurs as a result of venous hypertension caused by insufficiency of the muscle pump and valvar regurgitation. Pregnancy, the application of Caesarean section and the postpartum period predispose to deep vein thrombosis (DVT). The basic and unquestionable method applied in the prophylaxis and treatment of abnormalities to the venous-lymphatic system and corresponding complications consists in compression therapy involving compressive bandaging and the use of compression garments. Compression can be applied either individually or in combination with other methods, such as manual lymph drainage, intermittent pump compression and physical or breathing exercises. Based on the scientific evidence and experts’ recommendations, compression is also considered to be an effective solution in the prevention and treatment of deep vein thrombosis and swelling in pregnant women, but further investigation is needed. Ochałek K., Frydrych-Szymonik A., Szyguła Z. Lower-limb oedema during pregnancy. Med Rehabil 2016; 20(4): 17-21. DOI: 10.5604/01.3001.0009.5481
PL
Regularna aktywność fizyczna stosowana w okresie poprzedzającym ciążę oraz w czasie jej trwania w znacznym stopniu warunkuje prawidłowy przebieg tego niezwykle ważnego stanu w życiu kobiety. Celem niniejszej pracy jest prezentacja subiektywnych narzędzi badawczych najczęściej stosowanych do oceny aktywności ruchowej kobiet ciężarnych. Analizowano przydatność kwestionariuszy: Pregnancy Physical Activity Questionnaire, Kaiser Physical Activity Survey, International Physical Activity Questionnaire, Paffenbarger Physical Activity Questionnaire, Seven-Day Physical Activity Recall, Minnesota Leisure Time Physical Activity Questionnaire, oraz Activity Questionnaire for Adolescents and Adults. Z uwagi na wykazywane w licznych badaniach, prowadzonych na całym świecie, zjawisko ograniczania aktywności ruchowej wśród ciężarnych oraz znikomą ilość badań polskich w zakresie oceny aktywności fizycznej w grupie kobiet oczekujących narodzin dziecka, wydaje się zasadne propagowanie metod, które pozwolą na obserwację trendów tego zjawiska w Polsce. Wydaje się, iż jest to istotne w pracy lekarzy, położnych i fizjoterapeutów, których rolą jest m.in. promowanie zachowań prozdrowotnych.
EN
Regular physical activity in the period before and during pregnancy largely determines the correct course of this important state in the life ofa woman. The purpose of this paper is to present the subjective research tools most commonly used to assess physical activity in pregnant women. The following questionnaires were studied: Pregnancy Physical Activity Questionnaire, Kaiser Physical Activity Survey, International Physical Activity Questionnaire, Paffenbarger Physical Activity Questionnaire, Seven-Day Physical Activity Recall, Minnesota Leisure Time Physical Activity Questionnaire and Activity Questionnaire for Adolescents and Adults. Due to the phenomenon of limiting physical activity among pregnant women, reported in numerous studies conducted around the world, anda negligible amount of Polish research on the assessment of physical activity in pregnant women, it seems reasonable to promote methods that allow for the observation of trends of this phenomenon in Poland. It seems that tracking trends is important for the work of doctors, midwives and physiotherapists, whose role is to, among other things, promote healthy behaviour.
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