Wyniki wyszukiwania - Biblioteka Nauki

1

Occurrence of volatile N-nitrosamines in Polish tinned foods

100%

Domanska-Blicharz K. , Rachubik J. , Kowalski B.

Bulletin of the Veterinary Institute in Puławy

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2005

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tom 49

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nr 3

2

Influence of tobacco smoke on the pharmacokinetics of citalopram and its enantiomers

84%

Majcherczyk J. , Kulza M. , Senczuk-Przybylowska M. , Florek E. , Jawien W. , Piekoszewski W.

Journal of Physiology and Pharmacology

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2012

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tom 63

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nr 1

3

The impact of the modified method of using KNO3 on the formation of volatile N-nitrosamines in Gouda cheese

84%

Stasiuk E. , Przybylowski P.

Bromatologia i Chemia Toksykologiczna

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2006

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tom 39

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nr 1

4

Occurrence of volatile N-nitrosamines in Polish processed meat products

84%

Domanska K. , Kowalski B.

Bulletin of the Veterinary Institute in Puławy

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2003

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tom 47

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nr 2

5

Microbiological quality of Polish edible offals processed meat products during storage: influence on N-nitrosamines content

84%

Domanska K. , Rozanska H.

Bulletin of the Veterinary Institute in Puławy

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2003

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tom 47

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nr 1

6

Evaluating adult dietary intakes of nitrate and nitrite in Polish households during 2006-2012

67%

Anyzewska A. , Wawrzyniak A.

Roczniki Państwowego Zakładu Higieny

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2014

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tom 65

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nr 2

EN

Introduction. Nitrates and nitrites commonly occur throughout nature as well as in foodstuffs. Their excess consumption can however pose health risks, for example, arising from methaemoglobinaemia or from the formation of N-nitrosamines. Objectives. To determine whether the levels of domestic nitrate and nitrite consumption are safe in Polish households during 2006-2012. Material and methods. Appropriate consumption data was obtained from the Central Statistical Office in Poland (GUS), whilst nitrate and nitrite intakes were estimated from nationally available data on foodstuff content taken from the literature. Results. Mean nitrate and nitrite intakes were respectively 147 mg NaNO3 and 3.26 mg NaNO2 /per person/day, corresponding to 41% and 45% of the ADI (acceptable daily intake). Statistically significant differences in intakes were observed between types of households, with the highest seen in those of retired subjects; however the ADIs were not exceeded. Conclusions. Domestic intakes of nitrates and nitrites were found to be at safe levels; nevertheless control over their intake should be maintained because of potentially adverse health threats.

PL

Wprowadzenie. Azotany(V) i (III) występują zarówno w przyrodzie jak i w żywności. Nadmierne ich spożycie może powodować zagrożenie zdrowia, np. methemoglobinemię lub może przyczynić się do powstawania N-nitrozoamin. Cel badań. Celem badań było oszacowanie pobrania azotanów(V) i azotanów(III) z żywością w gospodarstwach domowych w Polsce w latach 2006-2012. Materiał i metody. Oszacowanie pobrania azotanów(V) i azotanów(III) w gospodarstwach domowych wykonano na podstawie danych o spożyciu żywności Głównego Urzędu Statystycznego (GUS) oraz zebranych krajowych danych z piśmiennictwa dotyczących zawartości tych związków w produktach spożywczych. Wyniki. Średnie pobranie azotanów(V) i azotanów(III) w latach 2006-2012 wynosiło 147 mg NaNO3/os/dobę (41% ADI) i 3,26 mg NaNO2/os/dobę (45% ADI). Pobranie azotanów(V) i azotanów(III) różniło się istotnie statystycznie w badanych typach gospodarstw domowych. Największe średnie pobranie zarówno azotanów(V) jak i azotanów(III) zaobserwowano w gospodarstwach emerytów, jednak wartości ADI nie zostały przekroczone. Wnioski. Średnie pobranie azotanów(V) i azotanów(III) w gospodarstwach domowych w latach 2006-2012 kształtowało się na bezpiecznym poziomie, niemniej jednak należy kontrolować pobranie tych związków z dietą ze względu na ryzyko możliwych negatywnych skutków zdrowotnych.

7

Effect of maternal tobacco smoking or exposure to second-hand smoke on the levels of 4-(methylnitrosamino)-1-(3-pyridyl)- 1-butanol (NNAL) in urine of mother and the first urine of newborn

67%

Florek E. , Piekoszewski W. , Basior A. , Merriti A. T. , Mazela J. , Lechowicz W. , Kornacka M. K. , Kramer L.

Journal of Physiology and Pharmacology

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2011

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tom 62

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nr 3

EN

Tobacco smoking during pregnancy is associated with a variety of negative consequences not only for the mother, but also for the developing fetus. Many studies have shown that carcinogens contained in tobacco smoke permeate across the placenta, and are found in fetus. The aim of the study was to determine the prenatal exposure to tobacco-specific carcinogenic N-nitrosamines on the basis of measurements of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in urine of smoking and second-hand smoke (SHS) exposed women and in the first urine of their newborns. A questionnaire documenting demographics and socio-economical data, smoking habits and exposure to SHS was completed by 121 delivering women near or at term. Maternal concentrations of cotinine and NNAL were measured in urine of the mother and the first urine of her newborn infant by liquid chromatography tandem mass spectrometry (LC/MS/MS). The mean concentration of cotinine was 439.2 ng/mg creatinine and NNAL concentration in urine of smoking women was 74.0 pg/mg creatinine, and for her newborn 78.6 pg/mg creatinine. Among mothers exposed to SHS, cotinine and NNAL mean concentration were 23.1 ng/mg creatinine, and 26.4 pg/mg creatinine. In newborns of SHS exposed mothers during pregnancy the mean concentration of NNAL was 34.1 pg/mg creatinine, respectively. Active tobacco smoking as well as passive exposure to smoking during pregnancy is an important source of tobacco specific N-nitrosamines to the fetuses as evidenced by increased concentrations of this carcinogen. Determination of NNAL in maternal urine samples can be a useful biomarker of prenatal exposure of newborn to carcinogenic nitrosamines.

8

Oznaczanie N-nitrozoamin w pelnej krwi metoda chromatografii gazowej z uzyciem detektora NPD

67%

Jablonski J. , Pikutin A. , Lukaszewicz-Hussain A. , Moniuszko-Jakoniuk J.

Acta Poloniae Toxicologica. Suplement

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1994

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tom 02

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nr 1

104-107

9

Effect of different storage conditions on nitrates and nitrites in Polish edible offals processed meat products. Influence on N-nitrosamine content

59%

Domanska-Blicharz K. , Michalski M. , Kowalski B.

Bulletin of the Veterinary Institute in Puławy

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2004

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tom 48

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nr 1

10

Porownanie zawartosci N-nitrozodimetyloaminy w wybranych produktach miesnych

51%

Ciemniak A.

Roczniki Państwowego Zakładu Higieny

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2006

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tom 57

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nr 4

341-346

PL

Przeprowadzono badania wybranych produktów mięsnych pod kątem zawartości w nich N—nitrozodimetyloaminy. Analizy wykonano techniką chromatografii gazowej sprzężonej ze spektrometria mas (GC-MS). Najwyższe zawartości N-nitrozodimetyloaminy stwierdzono w produktach peklowanych i wędzonych.

EN

Nitrosamines are know as the most potent group of carcinogens. Approximately 300of these compounds have been tested, and about 90% of them have been found to be carcinogenic in laboratory animals. N-nitrosodimethylamine causes liver cancer, whereas some of tobacco specific nitrosamines causes lung cancer. Volatile N-nitrosamines induce tumors in a variety of human organs, including the tongue, esophagus, lung, pancreas, liver, kidney and bladder. They are formed during reaction of secondary or tertiary amino compounds and nitrite or nitrogen oxides. Nitrosamines occurs as contaminants in many foodstuff including food and beverages: beers, cheeses, sausages, smoked and pickled foods. They are formed during frying, smoking and food preserved with pickling salt. These compounds can also be produced in man and other mammals under the acidic conditions in the stomach. The present study was carried out to determine level of N-nitrosodimethylamine in selected 13 meat products. The extraction procedure was based on Raoul's method, ie. on two consecutive extraction-concentration step using extrelut and florisil columns. The level of N-nitrosodimethylamine was varied from 0,049 mg/kg to 16,47 mg/kg. The highest level of NDMA was found in smoked sausage.

11

Czynnosc neutrofili krwi obwodowej [PMN] szczurow narazonych na dzialanie N-nitrozodimetyloaminy [NDMA]

51%

Jablonska E. , Jablonski J. , Pietruska Z. , Moniuszko-Jakoniuk J. , Brzoska M.

Bromatologia i Chemia Toksykologiczna

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1996

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tom 29

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nr 1

85-89

PL

W pracy oceniano aktywność fagocytarną neutrofllów krwi obwodowej szczura (PMN) w zależności od narażenia na N-nitrozodimetyloaminę (NDMA). Wyniki przeprowadzonych testów w konfrontacji ze stężeniem N-nitrozodimetyloaminy we krwi obwodowej zwierząt sugerują związek pomiędzy narażeniem na NDMA a zdolnością fagocytarną neutroflli.

EN

The aim of this study was to assess to phagocytic functions of PMN in peripheral blood of NDM A - exposed rats. The relationships between PMN functions and blood NDMA concentrations suggests that the observed decrease of neutrophil phagocytic functions was caused by NDMA.

12

Wybrane zagadnienia stosowania azotynu w przetworstwie miesa

51%

Duda Z.

Żywność Technologia Jakość

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1998

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tom 05

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nr 3

5-42