Wyniki wyszukiwania - Biblioteka Nauki

1

Animal genome mapping projects

100%

Fredholm M.

Biotechnologia

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1996

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nr 2

13-19

EN

During the latest years many examples have been provided illustrating that gene maps can be utilized fer search aiming at (i) isolation causing oe having an influence on certain diseases, (ii) studying the genomic organization an evolutionary relationship of mammalian species, and (iii) eveloping animal models of human disease.

2

Chromosomal assignment of R-spondin genes in the donkey (Equus asinus, 2n = 62)

80%

De_ L. L. , Genualdo V. , Perucatti A. , Pia_ D. M. G. , Molteni L. , Iannuzzi L. , Parma P.

Journal of Applied Genetics

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2010

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tom 51

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nr 3

319-321

EN

R-spondins constitute a recently discovered small family of growth factors, and the evidence of their role in several developmental pathways is growing fast. In this work we describe the chromosomal location of the four RSPO genes in the donkey. Using horse BACs, we localized RSPO1 on EAS 5q23, RSPO2 on EAS 12q13, RSPO3 on EAS 24q26, and RSPO4 on EAS 15p13. Moreover, RSPO2, RSPO3, and RSPO4 are the first genes mapped on donkey chromosomes 12, 24, and 15, respectively.

3

Embodied Mind, or the Problem of the Existence of the Soul in the Philosophy of Antonio Damasio

80%

Bankiewicz P.

Przegląd Filozoficzny. Nowa Seria

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2008

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tom 17

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nr 3(67)

5-19

EN

According to Antonio Damasio, consciousness and the sense of self consist of several hierarchically structured maps and representations. At the basic level there is a collection of neural patterns (first-order maps) that reflects the state of the organism's internal milieu. Higher mental levels re-represent this differentiation in the higher-order maps. Thus, we can speak of an embodied nature of the mind without denying its reality. To provide a background to Damasio's theory, the author raises the question about methodological frameworks. A comparison between Damasio's empirical theory and the traditional notion of the soul highlights the explanatory weakness of the latter. It pertains especially to the relationships between brain damage and changes of consciousness or the sense of self.

4

Application of a mixed inheritance model to the detection of quantitative trait loci in swine

80%

Szyda J. , Liu Z. , Grindflek E. , Lien S.

Journal of Applied Genetics

|

2002

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tom 43

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nr 1

69-83

EN

The primary goal of this study was to investigate statistical properties of a mixed inheritance model for the localization of quantitative trait loci (QTL). This is based on the analysis of phenotypic data for the amount of intramuscular fat (IMF) scored on 305 individuals originating from a cross between Duroc and Norwegian Landrace breeds. Marker genotype information is available for F1 and F2 generations. Statistical procedures compared involve i) the interval mapping, ii) the composite interval mapping, iii) a regression method, and iv) a mixed inheritance model accounting for a random animal additive genetic effect and relationships between individuals. The basic statistical properties of the latter approach are then assessed using Monte Carlo simulations showing slight unconservativeness as compared to and reasonable power to detect QTL of moderate effects. In the analysis of IMF data, the significant evidence for the existing QTL is detected on chromosome 6. A chromosomal region recommended for a second-step fine mapping analysis is identified between markers SW1823 and S0228, based on three types of confidence intervals derived by using: i) the Jackknife algorithm, ii) the numerical variance approximation, and iii) the LOD score approach. The Jackknife algorithm was additionally used to quantify each family?s contribution to the test statistic and to the estimate of QTL position.

5

Unidirectional orientation of twelve expressed tagged sites within 40 kb of human chromosomal region 22q13.1

80%

Pusch C. , Wang Z. , Roe B. , Blin N.

Journal of Applied Genetics

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1998

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tom 39

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nr 2

199-204

EN

. The single copy sequence D22S16 from human chromosomal region 22q13.1 that carries a putative conserved gene, was used to probe a chromosome 22-specific cosmid library. Genomic sequencing of one positive, 40 kb long cosmid (C1155) revealed a hereto unmapped gene (a subunit of DNA-dependent RNA polymerase II, POLR2F), a SOX9-related sequence and 12 expressed sequence tags. Although not parts of one consecutive gene, all 12 ESTs and, in addition, the polymerase gene are oriented in the same transcriptional direction within the genomic sequence represented by cosmid C1155.

6

Genetic mapping of the gene affecting polyphenol oxidase activity in tetraploid durum wheat

70%

Watanabe N. , Masum A. A. S. M. G. , Nachit M. M.

Journal of Applied Genetics

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2006

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tom 47

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nr 3

201-205

EN

The quality of durum wheat (Triticum turgidum ssp. durum) is influenced by polyphenol oxidase (PPO) activity and its corresponding substrates. A saturated molecular-marker linkage map was constructed previously by using a set of recombinant inbred (RI) lines, derived from a cross between durum wheat cultivars Jennah Khetifa and Cham 1. Quantitative trait loci (QTL) for PPO activity in seeds were mapped in this population. PPO activity in seeds of the parents and 110 RI lines was measured spectrophotometrically. The PPO activity of Cham 1 was significantly lower than that of Jennah Khetifa. QTL analysis of these data indicated that most of PPO activity was associated with major loci on the long arm of chromosome 2A. The trait was found to be strongly associated with the SSR marker Xgwm312@2A. With this knowledge, marker-assisted selection can be used to select genotypes with lower PPO activity in durum wheat populations.

7

FAKTORY ROZVOJA KLASTROVÝCH ORGANIZÁCIÍ V SLOVENSKEJ REPUBLIKE

70%

Balog M.

Ekonomický časopis (Journal of Economics)

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2016

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tom 64

|

nr 2

149 – 168

EN

A cluster concept represents one of widely discussed approach used by policy makers in many countries because clusters create conditions and overall environment for e.g. higher efficiency, stimulate cooperation, increase innovation performance as well as patent activities of individual firms. Moreover clusters belong to factors attracting foreign direct investments. The cluster concept has not been systematically used in the Slovakia by policy makers so far. Nevertheless, many technological cluster organizations as well as cluster organization in tourism have been created spontaneously. The paper presents results of the technology-oriented cluster organization mapping. Mapping shows that cluster policy if it is truly implemented has a significant potential to stimulate cluster development.

8

HETEROTOPIAS AND TRANSFORMATIONS IN ART AND SCIENCE

60%

Tomašovičová J.

World Literature Studies

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2017

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tom 9

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nr 3

3 – 13

EN

Michel Foucault characterized heterotopias as specific spaces which disrupt and overturn our existing systems, the hitherto valid order of things and also our ways of thinking. They are significantly important particularly from the point of view of culture, since they affect cultural dynamic transformations. The author in her contribution points out that we presently discover such specific spaces mainly by means of modern technologies. Regarding digital media, the database – a collection of digital data – has a heterotopic character; it neutralizes the present forms of orders and preferences. Images, sounds and words are loosened from their indexicality and are converted into numerical code, which enables the modification and combination of the obtained data. The database thus represents a new type of space which subverts the standard organization of signs. Modern technologies also unveil other unconventional spaces of our micro and macro worlds. The newest medical technologies such as ultrasound, computed tomography and magnetic resonance imaging penetrate through the surface of the human body into the depths of biological structures in order to obtain their image, and they indeed make the molecular system of the human organism visible. This molecular system can be characterized by high complexity, multifunctionality and highly variable interactions, and the medical technologies in a certain way contribute to the fact that our forms of knowledge are constantly enhanced, extended and sometimes even refuted. This current expansion of heterotopia corresponds with Foucault’s opinion that every epoch creates its own spaces which strive to gain their legitimacy. It is interesting that in both cases of the above-mentioned examples of heterotopia the data transformation can be seen as a significant form of their element arrangement, and thus the borders not only between semiotic systems but also between scientific and artistic discourses are gradually wiped out.

9

Interval mapping of QTLs controlling yield-related traits and seed protein content in Pisum sativum

60%

Irzykowska L. , Wolko B.

Journal of Applied Genetics

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2004

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tom 45

|

nr 3

297- 306

EN

A linkage map of garden pea was constructed on the basis of 114 plants (F2 generation) derived from a cross combination Wt10245 ? Wt11238. The map, consisting of 204 morphological, isozyme, AFLP, ISSR, STS, CAPS and RAPD markers, was used for interval mapping of quantitative trait loci (QTLs) controlling seed number, pod number, 1000-seed weight, 1000-yield, and seed protein content. Characterization of each QTL included identification of QTL position with reference to the flanking markers, estimation of the part of variance explained by this QTL, and determination of its gene action. The yield-related traits were measured in F2 plants and in F4 recombinant inbred lines (RILs). The interval mapping revealed two to six QTLs per trait, demonstrating linkage to seven pea chromosomes. A total of 37 detected QTLs accounted for 9.1-55.9% of the trait's phenotypic variation and showed different types of gene action. As many as eight and ten QTLs influencing the analysed traits were mapped in linkage groups III and V, respectively, indicating an important role of these regions of the pea genome in the control of yield and seed protein content.

10

The transpositional elements as a tool for plant genome mapping

51%

Wochniak P. , Malepszy S.

Biotechnologia

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1994

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nr 3

15-29

EN

This work aims at reviewing current progress in the field of plant transposble elements, especially those described as Ac/Ds and En/dSpm systems, first discovered in maize.We gave the molecular characteristics of plant transposones and the rules of their behaviour within a genome.The procedure for a particular gene mapping and for mapping of many genes responsible for biochemical pathway were cited.In comparison with other genome mapping methods the advantages and drawbacks of "gene tagging" were envisaged.The enclosed tables provide many documental examples of plant genes identification via "gene tagging" method.

11

URBAN CARTOGRAPHIES IN THE POST-COLD WAR ERA: POSTMODERN CHALLENGES TO ETHNOCENTRIC AND GLOBALIST MAPPINGS

51%

Cornis-Pope M.

World Literature Studies

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2009

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tom 1(18)

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nr 1

14-27

EN

The post-Cold war period has freed our topographic imagination of traditional ideological polarizations, but has often replaced these imperialistic mappings with cartographies of a nationalistic or ethnocentric kind that promote resentful cultural division. Much of this new ethnic and nationalist fundamentalism has emerged in direct reaction to the pressure of the First World's globalizing ideologies. The new tensions between global interdependency and ethnocentric separatism, First-World centres and Third-World peripheries, indicate a state of continued crisis at the level of the ideological frameworks within which cultural exchanges unfold. Neither a globalist notion of multiculturalism, nor a defensive localism is a proper approach to the issue of otherness. The alternative is the naive celebration of 'hybridity' and 'national centrism' (Homi Bhabha, Edward Soja and the others). The author asserts that we need 'narratives of relation positionality' (Susan Stanford Friedman) that will challenge traditional separations between self and other, western and non-western, male and female, global and local. The paper shows on examples from present American and Central Europe literature, that postmodernism is able to afford this 'narratives of relation positionality'.