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2 Acta Universitatis Lodziensis. Folia Biochimica et Biophysica

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Struktura i właściwości mucyn śluzowych

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Zaleśna G. , Gwożdziński K. , Uniwersytet Łódzki K. B. M.

tom 10

This review describes function and physico-chemical properties of gastrointestinal mucus. In perticular the role of mucins is shown. Recently studies of the chemical composition and structure of mucin is discussed. The biosynthesis of mucin and mechanism of viscoelastic gel-forming properties is described. In this review the function of mucus in gastric ulcer and cancer disease is shown.

Rola Helicobacter pylori w patogenezie chorób żołądka i dwunastnicy

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Zaleśna G. , Gwożdziński K. , Uniwersytet Łódzki K. B. M.

tom 11

The review article describes the role of H. pylori in pathogenesis of chronic gastritis, gastric and duodenal ulcers and gastric cancer. Possible mechanisms of mucosa damage by H. pylori was presented as well as the methods of diagnosis and therapy of these diseases.

Charakterystyka stanów chorobowych żołądka

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Brzeszczyńska J. , Gwoździński K. , Uniwersytet Łódzki K. B. M.

The paper describes different diseases of the human stomach with regard to the activity of Helicobacter pylori associated with them. It is believed that the Helicobacter pylori infection is always connected with damage of the surface of epithelium, which is accompanied by different degrees of inflammation. It was found, that the bacteria plays a crucial role in the patophysiology of most of stomach and duodenum diseases. Helicobacter pylori is most frequently reported to be the cause of stomach inflammations and cancer disease. It is also believed to cause stomach and duodenum ulcers. Helicobacter pylori has been detected in 60-80% of patients with ulcer disease and in about 90-100% patients with duodenum disease. The presence of Helicobacter pylori was observed in 50% of patients with dyspepsia and epigastric pains.