A new approach to the liver segmentation from 3D images is presented and compared to the existing methods in terms of quality and speed of segmentation. The proposed technique is based on 3D deformable model (active surface) combining boundary and region information. The segmentation quality is comparable to the existing methods but the proposed technique is significantly faster. The experimental evaluation was performed on clinical datasets (both MRI and CT), representing typical as well as more challenging to segment liver shapes.
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In this paper we present MESA: a platform for design and evaluation of medical image segmentation methods. The platform offers a complete approach for the method creation and validation using simulated and real tomographic images. The system consists of several modules that provide a comprehensive workflow for generation of test data, segmentation method development as well as experiment planning and execution. The test data can be created as a virtual scene that provides an ideal reference segmentation and is also used to simulate the input images by a virtual magnetic resonance imaging (MRI) scanner. Both ideal reference segmentation and simulated images could be utilized during the evaluation of the segmentation methods. The platform offers various experimental capabilities to measure and compare the performance of the methods on various data sets, parameters and initializations. The segmentation framework, currently based on deformable models, uses a template solution for dynamical composition and creation of two- and three-dimensional methods. The platform is based on a client–server architecture, with computational and data storage modules deployed on the server and with browser-based client applications. We demonstrate the platform capabilities during the design of segmentation methods with the use of simulated and actual tomographic images.
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The aim of the study is to investigate the potential of multi-sequence texture analysis in the characterization of prostatic tissues from in vivo Magnetic Resonance Images (MRI). The approach consists in simultaneous analysis of several images, each acquired under different conditions, but representing the same part of the organ. First, the texture of each image is characterized independently of the others. Then the feature values corresponding to different acquisition conditions are combined in one vector, characterizing a combination of textures derived from several sequences. Three MRI sequences are considered: T1-weighted, T2-weighted, and diffusion-weighted. Their textures are characterized using six methods (statistical and model-based). In total, 30 tissue descriptors are calculated for each sequence. The feature space is reduced using a modified Monte Carlo feature selection, combined with wrapper methods, and Principal Components Analysis. Six classifiers were used in the work. Multi-sequence texture analysis led to better classification results than single-sequence analysis. The subsets of features selected with the Monte Carlo method guaranteed the highest classification accuracies.
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