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1 World News of Natural Sciences

1 2020

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Design and Antimicrobial evaluation of 1-(2-(2,3,5-triphenylcyclopenta-2,4-dien-1-yl)ethyl)piperazine and their derivatives

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doss M. A. , Rajkumar R. , Prabhakaran A. , Dhineshkumar E. , Uma D.

World News of Natural Sciences

2020

tom 30

nr 2

213-219

A total of six of 1,2,4,5-tetrasubstituted imidazoles were prepared by multicomponent cyclo- condensation of benzil, aromatic aldehyde, aminoethylpiperazine and ammonium acetate. The prepared compounds were screened for their antibacterial activity against S. aureus, S. typhi, E.coli and Pseudomonas and antifungal activity against A. niger, C. albicans, Rhizopus sp, and Mucor. They exhibited better activities against all the tested bacterial and fungal strains.