Wyniki wyszukiwania - Biblioteka Nauki

1

Parallel evolutionary optimization of structures

100%

Thierauf G. , Cai J.

Computer Assisted Mechanics and Engineering Sciences

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2000

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tom Vol. 7, No. 4

735-742

EN

By introducing a variable coding technique, a parallel optimization method based on a combination of GAs and ESs is presented. The advantages of both GAs and ESs, like coding of genetic information and adaptation of optimization parameters, are enhanced by this new method.

2

Badania początkowego okresu hydratacji spoiw żużlowo-alkalicznych

80%

He J. , Cai J. , He J.

Cement Wapno Beton

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2017

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tom R. 21/83, nr 6

507--516

PL

W pracy badano, za pomocą pomiarów ciepła hydratacji oraz czasu wiązania zaczynów, wpływ rodzaju, składu i ilości aktywatora na proces hydratacji alkalicznie aktywowanego mielonego granulowanego żużla wielkopiecowego. W przypadku aktywatora w postaci szkła wodnego dla modułów krzemianowych w zakresie 0,8 – 2,0 czas wiązania zaczynów wydłużał się nieznacznie wraz ze zwiększaniem się modułu krzemianowego. Dla modułów mniejszych od 0,8 i większych od 2,0 czas wiązania znacznie się wydłużał. Wraz ze wzrostem modułu krzemianowego szkła wodnego wydłużał się również okres indukcji na krzywych szybkości wydzielania ciepła. Zwiększenie zawartości aktywatora z 3% do 6% Na2Oeq przy stałym module powodowało skrócenie czasu wiązania. W przypadku aktywacji NaOH, zależność ta była odwrotna. Dla spoiw aktywowanych NaOH wydzielanie ciepła hydratacji było bardziej intensywne, ciepło całkowite większe a okres indukcji krótszy niż w przypadku spoiw aktywowanych szkłem wodnym. Zwiększenie zawartości Na2O w aktywatorze powodowało zwiększenie całkowitego ciepła hydratacji niezależnie od rodzaju użytego aktywatora.

EN

In present work, heat of hydration and setting times measurements were used to investigate the influence of type, composition and amount of activator on the hydration process of alkali activated ground granulated blast furnace slag. In case of water glass used as an activator, for modulus within the range 0.8 - 2.0 setting time of pastes was increasing gradually. For water glass modulus values below 0.8 and over 2.0 significant increase of setting time was noted. Also duration of induction period on heat evolution curve was increasing with increase of modulus. Increasing activator amount expressed as Na2Oeq content from 3% to 6% at constant water glass modulus resulted in setting time shortening. In case of NaOH activated pastes, the reverse relationship was noted. For NaOH activated pastes, heat of hydration evolution was more intense, total amount of heat was higher and induction period was shorter comparing to pastes activated with water glass. Increase of Na2Oeq content within the system resulted in total amount of heat evolved increase independently of activator type.

3

Spanning trees with a bounded number of leaves

80%

Cai J. , Flandrin E. , Li H. , Sun Q.

Opuscula Mathematica

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2017

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tom Vol. 37, no. 4

501--508

EN

n 1998, H. Broersma and H. Tuinstra proved that: Given a connected graph G with n ≥ 3 vertices, if d(u) + d(y) ≥n — k + 1 for all non-adjacent vertices u and v of G (k ≥ 1), then G has a spanning tree with at most k leaves. In this paper, we generalize this result by using implicit degree sum condition of t (2≤ t ≤k) independent vertices and we prove what follows: Let G be a connected graph on n ≥ 3 vertices and k ≥ 2 be an integer. If the implicit degree sum of any t independent vertices is at least [formula] for (k≥ t ≥ 2), then G has a spanning tree with at most k leaves.

4

Bringing introspection into BlobSeer: Towards a self-adaptive distributed data management system

70%

Carpen-Amarie A. , Costan A. , Cai J. , Antoniu G. , Bougé L.

International Journal of Applied Mathematics and Computer Science

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2011

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tom Vol. 21, no 2

229-242

EN

Introspection is the prerequisite of autonomic behavior, the first step towards performance improvement and resource usage optimization for large-scale distributed systems. In grid environments, the task of observing the application behavior is assigned to monitoring systems. However, most of them are designed to provide general resource information and do not consider specific information for higher-level services. More precisely, in the context of data-intensive applications, a specific introspection layer is required to collect data about the usage of storage resources, data access patterns, etc. This paper discusses the requirements for an introspection layer in a data management system for large-scale distributed infrastructures. We focus on the case of BlobSeer, a large-scale distributed system for storing massive data. The paper explains why and how to enhance BlobSeer with introspective capabilities and proposes a three-layered architecture relying on the MonALISA monitoring framework. We illustrate the autonomic behavior of BlobSeer with a self-configuration component aiming to provide storage elasticity by dynamically scaling the number of data providers. Then we propose a preliminary approach for enabling self-protection for the BlobSeer system, through a malicious client detection component. The introspective architecture has been evaluated on the Grid'5000 testbed, with experiments that prove the feasibility of generating relevant information related to the state and behavior of the system.

5

Phytoremediation of phenol using Polygonum orientale and its antioxidative response

70%

Wang K. , Cai J. , Xie S. , Feng J. , Wang T.

Archives of Environmental Protection

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2015

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tom Vol. 41, no. 3

39--46

EN

Polygonum orientale with beautiful red flowers can be found as one dominant species in the vicinity of most water bodies and wetlands in China. However, its phytoremediation potential has not been sufficiently explored because little is known about its resistance to inorganic or organic pollutants. We investigated P. orientale response to low and moderate levels of phenol stress (≤ 80 mg L-1). Endpoints included phenol tolerance of P. orientale and the removal of the pollutant, antioxidant enzyme activities, damage to the cell membrane, osmotic regulators and photosynthetic pigments. In plant leaves, phenol stress significantly increased the activities of peroxidase (POD) and catalase (CAT), as well as the contents of proline, soluble sugars and carotenoids, whereas superoxide dismutase (SOD), H2O2 and electrolyte leakage (EL) levels remained unaltered. On the other hand, there were significant decreases of soluble protein and chlorophyll contents. We demonstrated that, in combination with phenol tolerance and its removal, P. orientale has efficient protection mechanisms against phenol-induced oxidative damage (≤ 80 mg L-1). We propose that P. orientale could be used as an alternative and interesting material in the phytoremediation of phenol.

6

Diverse changes in myelin protein expression in rat brain after perinatal methadone exposure

61%

Oberoi R. , Chu T. , Mellen N. , Jagadapillai R. , Ouyang H. , Devlin L. A. , Cai J.

Acta Neurobiologiae Experimentalis

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2019

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tom 79

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nr 4

EN

The national incidence of neonatal abstinence syndrome has dramatically increased over the last decade due to an increase in antenatal opioid exposure. Recent human and animal studies suggest that antenatal opioid exposure impacts the developing brain. The purpose of this study is to evaluate the effects of perinatal methadone exposure on myelination in multiple regions in the developing rat brain. Pregnant Sprague-Dawley rats were randomly assigned into three experimental groups and subsequently exposed to drinking water alone or drinking water containing methadone from 7 days post coitum through day 7 or through day 19 after delivery. Two male neonatal rats were randomly selected from each litter and terminated at day 19. The cerebral cortex, hippocampus, cerebellum, and brainstem were dissected and analyzed for three myelin specific proteins – CNP, PLP, and MBP – by Western blot analysis. All pups with exposure to methadone demonstrated decreased expression of CNP, PLP, and MBP in the cerebral cortex and hippocampus. In the cerebellum, PLP expression was down-regulated without apparent alteration of CNP and MBP expression. PLP and MBP expression, but not CNP expression, were significantly inhibited in the brainstem. Compared to the pups with postnatal methadone exposure via maternal milk through day 7, partial recovery of CNP and PLP expression only occurred in the cerebral cortices of the pups exposed through day 19. The findings show that antenatal opioid exposure in rat pups is associated with regionally-specific alterations in brain myelination that diversely affects myelin proteins.

7

Transformation of wheat Triticum aestivum with the HvBADH1 transgene from hulless barley improves salinity-stress tolerance

61%

Li P. , Cai J. , Luo X. , Chang T. , Li J. , Zhao Y. , Xu Y.

Acta Physiologiae Plantarum

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2019

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tom 41

|

nr 09

EN

Studies have shown that the stress tolerance of cereal plants to osmotic or salinity stresses can be improved to varying degrees by the overexpression of an introduced betaine aldehyde dehydrogenase (BADH) gene. In the present study, the HvBADH1 gene from Hordeum vulgare L. var. nudum Hook. f., encoding a cytosolic BADH, was transferred into Triticum aestivum via traditional Agrobacterium tumefaciens-mediated transformation. Molecular methods, such as PCR, Southern blot analysis, and real-time quantitative RT-PCR were used to identify the successful integration and expression of the HvBADH1 transgene in genetically transformed wheat lines. To detect the efficacy of the HvBADH1 transgene in the transformants, some pivotal physiological indicators that reflected abiotic stress tolerance were measured in individual transgenic plant lines. These indicators included intracellular K⁺ and Na⁺ contents or K⁺/Na⁺ ratio, relative conductivity, and malondialdehyde and glycine betaine (GB) concentrations in cells. The results revealed that all the tested transgenic lines could significantly increase the recruitments of K⁺ in their cytosol than the wild-type seedlings. Similarly, 11.59- to 21.82-fold greater accumulation of GB, 2.11–2.56 times higher calli relative growth rates, and 26.2–29.1% seedling survival rates were found in transgenic lines under 150 mM NaCl stressed conditions. Our results demonstrated that by overexpressing the HvBADH1 transgene in genetically transformed wheat, the overall salt tolerance of the target plants was significantly increased, and the damaging effects of high salinity were significantly reduced.

8

The intrabody targeting of hTERT attenuates the immortality of cancer cells

61%

Zhu X. , Yang N. , Cai J. , Yang G. , Liang S. , Ren D.

Cellular and Molecular Biology Letters

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2010

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tom 15

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nr 1

32-45

EN

hTERT (human telomerase reverse transcriptase) plays a key role in the process of cell immortalization. Overexpression of hTERT has been implicated in 85% of malignant tumors and offers a specific target for cancer therapy. In this paper, we describe an effective approach using a single-chain variable fragment (scFv) intrabody derived from monoclonal hybridoma directed against hTERT to attenuate the immortalization of human uterine cervix and hepatoma cells. The scFv we constructed had a high affinity to hTERT, and specifically neutralized over 70% of telomere synthesis activity, thereby inhibiting the viability and proliferation of the cancer cells. Our results indicate that this anti-hTERT intrabody is a promising tool to target hTERT and intervene in the immortalization process of cancer cells.

9

Alteration of nutrient allocation and transporter genes expression in rice under N, P, K, and Mg deficiencies

61%

Cai J. , Chen L. , Qu H. , Lian J. , Liu W. , Hu Y. , Xu G.

Acta Physiologiae Plantarum

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2012

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tom 34

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nr 3

EN

Nitrogen (N), phosphorus (P), potassium (K), and magnesium (Mg) have essential physiological functions in plants. Their interactions in plants are not fully understood especially at the molecular level. In this study, we detected the physiological and molecular responses of rice plants at the vegetative growth phase to N, P, K, and Mg starvations. Deficiencies of N and P resulted in accumulation of soluble sugar and starch in the leaves. The root to shoot ratio increased under N and P deficiencies, but decreased under K and Mg deficiencies. In addition, deficiency of either K or Mg resulted in accumulation of the other cation in shoots. Moreover, K starvation decreased both K and soluble sugar contents in the roots pronouncedly. RT-PCR analysis showed that several sugar transporter genes in the leaves orchestrated with sugar accumulation induced by the nutrient shortages. Expression of a high affinity K transporter gene (OsHAK1) and a putative Mg transporter gene (OsMGT) showed opposite down- and up-regulation in the roots by K starvation. These findings suggest that deficiencies of the major nutrients suppressed the export of carbohydrates from source leaves. The regulated sugar and nutrient transporter genes investigated in this study could be used for elucidating the molecular mechanism of plants in their adaptation to varied nutrient supply.

10

Heavy metals in wheat grown in sewage irrigation: a distribution and prediction model

51%

Yu X. , Wang Z. , Lynn A. , Cai J. , Huangfu Y. , Geng Y. , Tang J. , Zeng X.

Polish Journal of Environmental Studies

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2016

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tom 25

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nr 1

EN

The distribution of and prediction models for heavy metals in wheat were evaluated in Tianjin, China. The results indicated that there were high heavy metal concentrations (Zn, Cd, Cu, Pb, Cr, and Ni) in the wheat and that the Cd concentration (0.062mg·kg-1) in the seeds actually exceeded the national safety standard. The accumulation factors for the wheat’s seeds were of a decreasing order: Zn>Cd>Cu>Pb>Cr>Ni. The Cd concentration in the wheat’s seeds corresponded closely with the Cd concentration in the soil (r = 0.74). The predicting model was appropriate for predicting the concentration of Cd and Zn in wheat, and the r was 0.735 and 0.625, respectively.

11

Identification, expression analysis, and function evaluation of 42 tomato DEAD-box RNA helicase genes in growth development and stress response

51%

Cai J. , Meng X. , Li G. , Dong T. , Sun J. , Xu T. , Li Z. , Han Y. , Zhu M.

Acta Physiologiae Plantarum

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2018

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tom 40

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nr 05

12

Health risks of heavy metals uptake by crops grown in a sewage irrigation area in China

51%

Wang Z. , Zeng X. , Geng M. , Chen C. , Cai J. , Yu X. , Hou Y. , Zhang H.

Polish Journal of Environmental Studies

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2015

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tom 24

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nr 3

EN

Ecological risks of heavy metal toxicity such as Cd, Cu, Pb, Zn, Cr, As, and Hg through crops (wheat and rice) grown in the Tianjin sewage irrigation area in northern China were studied in this paper. Wheat and rice samples as well as related soil samples from 77 select blocks were collected. The second grade of standards for Tianjin soil environmental quality was used for soil risk assessment. Chinese National Food Safe Criterion was used for health risk assessment of wheat and rice grains. Daily intake rate and Target hazard quotient were used for the potential health risk assessment of local population through the intake of wheat and rice grown in the sewage-irrigated site. The results showed that continuous application of wastewater has led to accumulation of heavy metals in the soil, and Cd, Zn, and Hg were the main pollutants. Zn and Cd were more mobile than other metals. Pb in wheat and rice had an ecological risk to human health. As and Hg in some rice samples as well as Cd, Zn, and As in some wheat samples had potential risk. Target hazard quotient (THQ) of individual metal was below 1.0, meaning the relative absence of health risks associated with intake of a single heavy metal through intake of either wheat or rice. THQs of As for wheat and rice would sum up to above 1.0, indicating As may pose a risk to the local population by intake of wheat and rice.

13

Aberrant changes of somatostatin and neuropeptide Y in brain of a genetic rat model for epilepsy: tremor rat

51%

Xu X. , Guo F. , Cai X. , Yang J. , Zhao J. , Min D. , Hao L. , Cai J.

Acta Neurobiologiae Experimentalis

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2016

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tom 76

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nr 3

EN

Excessive excitation or loss of inhibitory neurotransmission has been closely related to epileptic activity. Somatostatin (SST) and Neuropeptide Y (NPY) are members of endogenous neuropeptides which are recognized as important modulator of classical neurotransmitter, distributed abundantly in mammalian central nervous system. Abnormal expression of these two neuropeptides evidenced in some epileptic models highlights the relevance of SST or NPY in the pathogenesis of epilepsy. The tremor rat (TRM) is a genetic epileptic animal model which can manifest tonic convulsions without any external stimuli. The present study aimed to investigate the distribution and expression of SST and NPY in TRM brains, including hippocampus, temporal lobe cortex and cerebellum. Our RT‑PCR data showed that up‑regulated mRNA expression of SST and NPY was discovered in TRM hippocampus and temporal lobe cortex compared with control (Wistar) rats. The peptide levels of these neuropeptides in brain areas mentioned above were both apparently higher than that in normal Wistar rats as well. However, in cerebellums, neither SST nor NPY was significantly changed compared with control group. The immunohistochemical data showed that SST and NPY were widely present throughout CA1, CA3 and the hilus of hippocampus, the entorhinal cortex of temporal lobe cortex, as well as cerebellar Purkinje layer. In conclusion, our results discovered the aberrant changes of SST and NPY in several TRM brain regions, suggesting that the peptidergic system might be involved in TRM epileptiform activity.

14

Effects of spermine supplementation on blood biochemical parameters, amino acid profile and ileum expression of amino acid transporters in piglets

51%

Fang T. , Jia G. , Zhao H. , Chen X. , Wu C. , Xue B. , Cai J. , Tian G. , Wang J. , Liu G.

Journal of Animal and Feed Sciences

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2019

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tom 28

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nr 4