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1
Ultrasound vocalisation (USV) alterations in Purkinje cell specific TSC1 knockout mice
100%
Wiaderkiewicz J. , Barski J. J.
Acta Neurobiologiae Experimentalis
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2013
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tom 73
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nr Suppl.1
EN
Tuberous sclerosis (TSC) is a genetic disorder, characterized by the emergence of multi-system benign tumors. Symptoms related to central nervous system disruptions include seizures, developmental delay and a varying range of behavioral disorders. Behavioral disorders can be identified by analyzing various parameters, many of which can be observed during social interactions where different types of communication come into play. One of the more universal methods of communication in mammals is vocalization, which in mice is realized both in the audible and ultrasonic range. We recorded and analyzed mouse vocalizations during a mousepup isolation test, where newborn mice emit the largest amount of USV’s. A range of sound parameters were analyzed including the rate of vocalization and numerous physical characteristics of sound, as well as single calls which were identified and classified.
2
Socialization assessment of TSC1 knockout mice
100%
Wiaderkiewicz J. , Barski J. J.
Acta Neurobiologiae Experimentalis
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2014
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tom 74
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nr 3
EN
Tuberous sclerosis (TSC) is a genetic disorder, linked to the TSC1 gene and characterized by the emergence of multi-system benign tumors. Symptoms related to central nervous system disruptions include seizures, developmental delay and a varying range of behavioral disorders. These disorders can be identified by analyzing various parameters, many of which can be observed during social interactions. Cre recombinase mediated TSC1 gene knockout mice were constructed and analyzed for sociability and preference for social novelty. The test was performed in a standard threechamber sociability cage and results were obtained and analyzed using automated tracking software Ethovision XT from Noldus.
3
Ultrasonic vocalizations (USV) in the three standard laboratory mouse strains: developmental analysis
80%
Wiaderkiewicz J. , Glowacka M. , Grabowska M. , Barski J.-J.
Acta Neurobiologiae Experimentalis
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2013
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tom 73
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nr 4
EN
Mice, similarly to some other rodent species, communicate with specialized sounds in the ultrasonic range called ultrasonic vocalizations (USV). Evaluation of this behavioral activity enables estimation of the social interactions in animal models of autistic spectrum disorders (ASD). Because transgenic mouse models are generated, in most cases, on the mixed 129SV/ C57BL6 genetic background, we were interested if parameters that characterize USV differ between these two mouse strains. In addition, we wanted to compare these strains with the BALB/c line. In order to analyze USV, we applied the standard isolation test to newborn animals and compared standard parameters. Obtained results indicate clear differences between the 129SV and C57BL6 strains in respect to all analyzed USV parameters. Both strains behave also differently when compared with the BALB/c strain. For this reason in experiments utilizing transgenic animals, contribution of various genetic backgrounds has to be carefully considered.
4
Bacterial infections and osteoclastogenesis regulators in men and women with cholesteatoma
51%
Likus W. , Siemianowicz K. , Markowski J. , Wiaderkiewicz J. , Kostrzab-Zdebel A. , Jura-Szoltys E. , Dziubdziela W. , Wiaderkiewicz R. , Los M. J.
Archivum Immunologiae et Therapiae Experimentalis
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2016
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tom 64
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nr 3
5
Kryteria oceny zmian zawartości niklu w środowisku przyrodniczym w zasięgu wpływu punktowego źródła emisji
51%
Rochel R. , Kwapuliński J. , Zielonka K. , Griger D. , Wiaderkiewicz J. , Kmak-Kapusta D. , Jablecka D. , Surma M.
Ekologia i Technika
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2009
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tom R. 17, nr 4
140-145
PL
Wartości współczynnika specyficznej kumulacji dla badanych roślin zebranych w zasięgu emisji huty Miasteczka Śląskiego w porównaniu do wartości obserwowanych dla roślin z terenów Tatrzańskiego Parku Narodowego są większe od 50 do 320 razy [7]. Porównanie to dotyczy tylko przeciętnej zawartości pierwiastka w danym gatunku roślin (n = 10) występujących na danym terenie. Dla oceny zmian w środowisku przyrodniczym, nadaje się współczynnik specyficznej kumulacji niklu ustalony dla pokrzywy zwyczajnej (Urtica dioica L.), jako gatunku wszędobylskiego.
EN
The factor of specific accumulation for collected plants in range of influence of emission Miasteczko Śląskie smelter in comparison to observed values for plants from Tatra National Park are greater about 50-320 times. The comparison concerning only average element content in given species of plants (n = 10), occurring on this areas. For estimation of the changes in environment applicate one factor of specific accumulation of nickel, established for Urtica dioica L., as everywhere species.
6
Kryteria oceny zmian zawartości niklu w środowisku przyrodniczym w zasięgu wpływu punktowego źródła emisji
51%
Rochel R. , Kwapuliski J. , Zielonka M. , Griger D. , Wiaderkiewicz J. , Kmak-Kapusta D. , Jabecka D. , Surma M.
Ekologia i Technika
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2009
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tom 17
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nr 4
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