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Gut microbiota was analyzed in children, aged 6–18 months and su$ering from atopic dermatitis before and after 3 month supplementation of their diet with Lactobacillus casei DN – 114001 in a dose of 10⁹ cells daily. On completion of this period the total number of fecal Lactobacillus sp. cells decreased from 7.86 Log₁₀ CFU/g to 6.40 Log₁₀ CFU/g. After the next 5 months (without dietary supplementation with the probiotic bacteria) the level of Lactobacillus sp. cells was maintained at the latter value. During the dietary supplementation with the probiotic strain, the level of Bifidobacterium cells was maintained at 6.15–6.89 Log₁₀ CFU/g while after 5 months it decreased to 5.57 Log₁₀ CFU/g. The population of Clostridium sp. was reduced after 3 months of dietary supplementation from 6.49 to 5.83 Log₁₀ CFU/g and was maintained at the latter level during the next 5 months. The dietary supplementation had no effect on populations of Bacteroides sp., Enterococcus sp. and Enterobacteriaceae. Supplementation of children who developed atopic dermatitis with the preparation of Lactobacillus casei DN – 114001 positively affected their gut microbiota in terms of bifidobacteria and clostridia populations.
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