Purpose: The aim of the study is comparative analyze the Health Related Quality of Life (HRQOL); effect of social-demographic factors on quality of life also taking into account four domains and effect of the duration of disease on quality of life. Material and Methods: The evaluation of the quality of life in patients with rheumatoid arthritis (RA)(n=64), ankylosing spondylitis (AS) (n=60) and systemic sclerosis (SSc) (n=63) was conducted with the use of a standardized research tool - WHOQOL Bref. Results: The conducted general analysis of particular life quality domains showed that for RA patients the weakest domain was the one related the environment (11.3) and physical health (11.6), with the strongest social domain (14.7). The respondents with AS had the lowest score for physical health (12.2), also with the strongest social domain (14.2). The results obtained from SSc patients are slightly better than for RA and AS patients as regards physical health (12.6) and the environment (13.9). Conclusions: It seems that, taking into account the patient’s own opinion about the treatment and its consequences by means of QOL evaluation, makes the patient a partner in the process of treatment and nursing, which leads to a greater humanization of medicine.
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