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A novel biocompatibility test for disperse materials

100%

Tereshchenko V. , Degtiariova L. , Segeda T. , Ivanova O. , Zinabadinova S. , Lavrinenko V.

Journal of Pre-Clinical and Clinical Research

2015

tom 09

nr 1

Introduction. Development of novel biocompatibility tests represents an urgent problem. Use of chicken embryos minimizes the effect of exogenous factors on the experimental course (as the chicken embryo develops in medium it is almost completely isolated from external effects), enables the observation of physiological and pathological processes in the dynamics and assessment of the response of the body response to various materials in many cell populations. Objective. We aimed to show the possibility of using chicken embryo as a test system for evaluation of the biological effects of powdered materials. Materials and methods. In this study, we applied developing chicken embryos produced by incubation of Highline white eggs. Test and control groups (200 embryos in total) were used. Powdered materials were introduced into the embryo yolk sac in the form of suspension in biocompatible dextran (rheopolyglucine).The material was sterilized for 60 min at 120 °С. Two disperse materials, activated charcoal and asbestos powders, were selected to assess the capabilities of the method. Morphological (review, selective histochemical, and electron microscopy) examination methods were applied in testing, which produced the following results. Results. Model efficacy was confirmed by testing certain substances, such as activated charcoal and asbestos. Faster growth and accelerated development of chicken embryos, the absence of tissue pathological reactions, was indicative of the biocompatibility of activated charcoal. Poor biocompatibility of asbestos was concluded from its multiple teratogenic effects detected for the first time for this material. Conclusions.The paper contains motivation and experimental data regarding the usability of chicken embryos in integrated testing of disperse material biocompatibility.

CO2 storage potential of sedimentary basins of Slovakia, the Czech Republic, Poland and the Baltic States

59%

Šliaupa S. , Lojka R. , Tasáryová Z. , Kolejka V. , Hladík V. , Kotulová J. , Kucharič L. , Fejdi V. , Wójcicki V. , Tarkowski R. , Uliasz-Misiak B. , Šliaupienė R. , Nulle I. , Pomeranceva R. , Ivanova O. , Shogenova A. , Shogenov K.

Geological Quarterly

2013

tom Vol. 57, No. 2

219–-232

It has been increasingly realised that geological storage of CO2 is a prospective option for reduction of CO2 emissions. The CO2 geological storage potential of sedimentary basins with the territory of Slovakia, the Czech Republic, Poland, and the Baltic States is here assessed, and different storage options have been considered. The most prospective technology is hydrodynamic trapping in the deep saline aquifers. The utilisation of hydrocarbon (HC) fields is considered as a mature technology; however storage capacities are limited in the region and are mainly related to enhanced oil (gas) recovery. Prospective reservoirs and traps have been identified in the Danube, Vienna and East Slovakian Neogene basins, the Neogene Carpathian Foredeep, the Bohemian and Fore-Sudetic Upper Paleozoic basins, the Mesozoic Mid-Polish Basin and the pericratonic Paleozoic Baltic Basin. The total storage capacity of the sedimentary basins is estimated to be as much as 10170 Mt of CO2 in deep saline aquifer structures, and 938 Mt CO2 in the depleted HC fields. The utilisation of coal seams for CO2 storage is related to the Upper Silesian Basin where CO2 storage could be combined with enhanced recovery of coal-bed methane.