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1 Acta Poloniae Pharmaceutica - Drug Research

1 2020

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BIOLOGICAL ACTIVITIES OF DIFFERENT EXTRACTS FROM ALLIUM URSINUM LEAVES

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Tomovic M. T. , Krivokapic M. Z. , Jakovljevic V. L. , Sovrlic M. M. , Bradic J. V. , Petkovic A. M. , Radojevic I. D. , Brankovic S. R. , Comic L. R. , Andjic M. M. , Kocovic A. G.

Acta Poloniae Pharmaceutica - Drug Research

2020

tom 77

nr 1

121-129

The aim of our study was to evaluate and compare antioxidant and antimicrobial activity of aqueous, methanol and chloroform extracts of leaves of Allium ursinum (A. ursinum). Total phenol (TPC) and flavonoid (TFC) content in extracts and antioxidant activity using DPPH (1,1- diphenyl-2-picrylhydrazyl) assay were determined spectrophotometrically. In vitro antimicrobial activity was tested by microdilution method. The highest TPC and TFC were observed for chloroform extract. The extracts showed different degrees of antimicrobial activity. The intensity of antimicrobial action varied depending on the group of microorganism and the type of extracts. Our results demonstrated rational basis for the traditional uses of A. ursinum in alleviation of oxidative stress and against various pathogenic microorganisms.