The study was designed to determine the effects of dystocia on plasma cortisol, cholesterol, and vitamin levels in heifers (n=22) and their newborn calves (n=22) at delivery. The animals were classified into 4 groups depending on calving difficulty. Plasma cortisol concentrations were significantly elevated in dystocia heifers (P<0.001) and their calves (P<0.019). Similarly, cholesterol levels were also markedly increased in dystocia heifers (P<0.001) and their calves (P<0.007). Vitamin A, β-carotene, and vitamin C levels were significantly decreased in dystocia calves. Overall, plasma glucose, HDL, triglycerides, and creatinine levels were all markedly increased in dystocia heifers as compared to controls. However, glucose, HDL, triglycerides, and creatinine levels were not changed significantly in affected heifers as compared to control group. Calving stress appears to affect several blood parameters including cortisol, cholesterol, and vitamin A in all the groups and β-carotene and vitamin C in the calves. The analyses of these parameters can be practical to improve the health of dystocia-affected mothers and to increase survival of their newborns.
The purpose of this prospective, double-blinded, and placebo-controlled clinical trial was to investigate the efficacy of topical cream, containing 0.1% retinoic acid for the treatment of tail gland hyperplasia in cats. Nineteen privately owned cats diagnosed with tail gland hyperplasia, based on history and clinical findings were randomly assigned to either a placebo or an active ingredient treatment group. Clinical evaluations were done by the same investigator, who scored clinical healing, at the beginning, during, and at the end of the treatment. Both owners and investigators were blinded to the allocation to the groups. It was demonstrated that retinoic acid gel treatment significantly decreased (P<0.05) the investigator's clinical scores while no significant changes were detected in the placebo treatment group. In conclusion, treatment with 0.1% retinoic acid cream was effective for the topical management of tail gland hyperplasia in the cats included in the study.
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