Wyniki wyszukiwania - Biblioteka Nauki

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Modern porous polymer and carbon materials based on polyurethanes for applications in medical diagnostics

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Swinarew A. S. , Kubik K. , Gabor J. , Paluch J. , Popczyk M. , Stanula A. , Okła H. , Świerczyński A.

Engineering of Biomaterials

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2021

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tom Vol. 24, no. 163

33

2

Organic bacteriostatic material

100%

Flak T. , Paluch J. , Gabor J. , Okła H. , Stanula A. , Markowski J. , Plich J. , Swinarew A. S.

Engineering of Biomaterials

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2020

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tom Vol. 23, no. 155

17--21

EN

The use of antibiotics to treat bacterial infections is becoming less and less effective year by year due to the increasing resistance of bacteria. The microbial evolutionarily acquired resistance to antibiotics increases the threat to man’s life due to difficulties regarding effective therapies to fight infections. Therefore, apart from treatment, it is necessary to introduce appropriate prophylaxis which limits the multiplication of bacterial colonies on everyday use objects. Due to the antibiotic resistance phenomenon, it is important to find a new material with antibacterial properties for FDM 3D printing in medical applications. The work contains research on a new chemical compound used as an additive to thermoplastics. The rhodamine derivative was synthesized via the 4-diphenylaminobenzaldehyde reaction with 1.3-indendione in a boiling mixture of EtOH/H2SO4. The obtained chemical compound was used as a bacteriostatic modifier of the polycarbonate (PC) properties, as such a modification enables application e.g. for medical device housings or for surfaces frequently touched by people. The modifier and the commercially available polymer were compounded with a high-temperature screw extruder and a filament for FDM 3D printer was created. The modified polymer revealed antibacterial properties relative to Escherichia coli and good thermal stability during the processing.

3

Porowate materiały poliuretanowe do zastosowań w diagnostyce medycznej

100%

Swinarew A. S. , Muskus M. , Gabor J. , Paluch J. , Popczyk M. , Swinarew B. , Stanula A. , Kubik K. K. , Okła H. , Liszka B.

Przemysł Chemiczny

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2019

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tom T. 98, nr 2

251--256

PL

Opracowano proces wytwarzania pianek węglowych (synteza, karbonizacja), a także dokonano ich szerokiej charakterystyki, wykorzystując mikroskopię świetlną, skaningową mikroskopię elektronową SEM, mikrotomografię komputerową μCT, spektroskopię w podczerwieni FT-IR i chromatografię gazową sprzężoną z detektorem mas GC-MS. Wyniki przeprowadzonych badań umożliwiły wyselekcjonowanie pianek o najlepszych właściwościach sorpcyjnych, które mogą znaleźć zastosowanie w diagnostycznych badaniach fazy oddechowej.

EN

Polyurethane (PUR) foams were synthetized from polyols and methylene diphenyl diisocyanate polymers at mass ratios 1:1, 1:3 and 3:1 without any catalyst or in its presence. The porous structure of the PUR foams was detd. by using scanning electron microscopy and high-resolution 3D computed tomog. The PUR foams showed a good sorbability and could be used in the human diagnostic (respiratory phase).

4

Cartilage tissue examination using atomic force microscopy

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Paluch J. , Markowski J. , Pilch J. , Smółka W. , Jasik K. P. , Kilian F. , Likus W. , Bajor G. , Chrobak D. , Glowka K. , Starczewska O.

Engineering of Biomaterials

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2022

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tom vol. 25, no. 167

17--23

EN

Life sciences, a field closely intertwined with human biology and physiology, employ various research methods, including morphology studies and quantitative analysis through non-destructive techniques. Biological specimens often consist of three-phase structures, characterized by the presence of gas, liquid, and solid components. This becomes crucial when the chosen research methodology requires the removal of water from samples or their transfer to a cryostat. In the current research, mechanical and topographical examination of cartilage was performed. The materials were generously provided by the Department of Anatomy at the Medical University of Silesia, thereby eliminating any concerns regarding their origin or ethical use for scientific purposes. Our research methodology involved the application of atomic force microscopy (AFM), which minimally disrupts the internal equilibrium among the aforementioned phases. Cartilage, recognized as a ‘universal support material’ in animals, proves to be highly amenable to AFM research, enabling the surface scanning of the examined material. The quantitative results obtained facilitate an assessment of the internal structure and differentiation of cartilage based on its anatomical location (e.g., joints or ears). Direct images acquired during the examination offer insights into the internal structure of cartilage tissue, revealing morphological disparities and variations in intercellular spaces. The scans obtained during the measurements have unveiled substantial distinctions, particularly in the intercellular ‘essence’, characterized by granularities with a diameter of approximately 0.5 μm in ear cartilage and structural elements in articular cartilage measuring about 0.05 μm. Thus, AFM can be a valuable cognitive tool for observing biological samples in the biological sciences, particularly in medicine (e.g. clinical science).