Wyniki wyszukiwania - Biblioteka Nauki

Nowa wersja platformy, zawierająca wyłącznie zasoby pełnotekstowe, jest już dostępna.
Przejdź na https://bibliotekanauki.pl

Ograniczanie wyników

Znaleziono wyników: 4

Liczba wyników na stronie

Wyniki wyszukiwania

Sortuj według:

Ogranicz wyniki do:

Hemolityczna aktywnosc paleczek Klebsiella pneumoniae i Klebsiella oxytoca

100%

Szramka B. , Kurlenda J. , Bielawski K.

Medycyna Doświadczalna i Mikrobiologia

1998

tom 50

nr 3-4

207-213

Niniejsza praca przedstawia wyniki badań nad aktywnością hemolityczną wybranych szczepów Klebsiella pneumoniae i Klebsiella oxytoca. Badane szczepy wykazywały aktywność hemolityczną specyficzną wobec erytrocytów króliczych. Hemoliza występowała tylko po inkubacji hodowli z ß-merkaptoetanolem lub chlorkiem wapnia.

We demonstrated that Klebsiella pneumoniae and Klebsiella oxytoca possess a selective haemolytic activity on rabbit erythrocytes. Thirty one Klebsiella strains (18 strains of K. pneumoniae and 13 strains of K. oxytoca) were isolated from hospitalized patients. The liquid (Trypcase-soy broth - TSB) and solid (Trypcase-soy agar - TSA) medium, containing the red cells were used for the tests. All the screened strains showed a haemolytic effect on rabbit erythrocytes, provided that the supernatants of the cultures were preincubated with ß-mercaptoethanol or calcium chloride. There was no human and sheep erythrocyte lysis.

Hemolizyny aktywowane tiolem jako markery wirulencji bakterii

100%

Szramka B. , Kurlenda J. , Podhajska A.

Biotechnologia

2001

nr 3

Bactericidal effect of photodynamic therapy against methicillin-resistant Staphylococcus aureus strain with the use of various porphyrin photosensitizers

100%

Grinholc M. , Szramka B. , Olender K. , Graczyk A.

nr 3

Photodynamic therapy (PDT) is based on photosensitizers activated by light of appropriate wavelength. Their activation leads to generation of singlet oxygen and free radicals responsible for the cytotoxic effect. The aim of this project was to compare the bactericidal effect of PDT using different porphyrin photosensitizers against a methicillin-resistant Staphylococcus aureus strain. Exogenous sensitizers (protoporphyrin IX and newly synthesized derivative, protoporphyrin diarginate) induced a 3 log10-unit reduction in bacterial viable counts. With the use of endogenous, ALA-induced porphyrins, a 1.6 log10-unit reduction was obtained. The sensitizers tested executed their antibacterial activity with no essential change in the antibiotic resistance pattern of the studied strain.

Photodynamic effect of lanthanide derivatives of meso-tetra[N-methyl-4-pyridyl]porphine against Staphylococcus aureus

88%

Jurczak A. , Szramka B. , Grinholc M. , Legendziewicz J. , Bielawski K. P.

Acta Biochimica Polonica

2008

tom 55

nr 3

581-585

Photodynamic therapy (PDT), used for cancer treatment, is also an alternative method for eradication of drug-resistant bacteria. This method utilizes a nontoxic light-activated dye, called a photosensitizer, and visible light to produce reactive oxygen species that lead to bacterial cell death. The purpose of this study was to investigate the bactericidal effect of PDT using lanthanide derivatives of meso-tetra(N-methyl-4-pyridyl)porphine against Staphylococcus aureusstrains. The new photosensitizers appeared to be photodynamically ineffective. No enhancement of antistaphylococcal activity of TMPyP was observed after the conjugation of the porphyrin with lanthanide ions. Additionally, a significant difference in the susceptibility of two bacterial strains to unmodified TMPyP was observed.