Wyniki wyszukiwania - Biblioteka Nauki

Nowa wersja platformy, zawierająca wyłącznie zasoby pełnotekstowe, jest już dostępna.
Przejdź na https://bibliotekanauki.pl

Ograniczanie wyników

Znaleziono wyników: 2

Liczba wyników na stronie

Wyniki wyszukiwania

Sortuj według:

Ogranicz wyniki do:

Theoretical study of electron transport properties of an organic molecule

100%

Nara J. , Geng W. T. , Kino H. , Kobayashi N. , Ohno T.

tom Vol. 23, No. 2

383--387

Electron transport properties of benzene-(1,4)-dithiolate sandwiched between two gold electrodes were investigated using first-principles calculations. It was found that the peak energies and the peak widths in the transmission spectra are strongly dependent on the contact structures. Furthermore, the contributions of MOs to the transmission coefficients also depend on the contact structures. Especially, only the channel related to HOMO-3, HOMO, and LUMO+1 contributes to the conductance at zero bias. These results suggest that the determination of the contact structure is essential for estimating the properties of molecular devices.

Evaluation of the time period for which real-time polymerase chain reaction detects dead bacteria

72%

Choe H. , Inaba Y. , Kobayashi N. , Miyamae Y. , Ike H. , Fujimaki H. , Tezuka T. , Hirata Y. , Saito T.

nr 4

Real-time polymerase chain reaction (PCR) is currently widely used for the diagnosis of infections. We evaluated the time after treatment during which real-time PCR can detect dead bacteria. The presence of bacterial DNA was identified by real-time PCR through methicillin-resistant Staphylococcus (MRS)-PCR and universal PCR. Methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus epidermidis, and Escherichia coli were each killed with alcohol, antibiotics, or heat treatment in vitro. The detection periods of MRS-PCR for MRSA treated by alcohol, vancomycin, linezolid, and heat were found to be less than 16, 8, 12, and 8 weeks, respectively. The detection period of universal PCR for S. epidermidis treated by alcohol, cefazolin, and heat was less than 20, 20, and 4 weeks, whereas that for E. coli was 8, 20, and 4 weeks, respectively. The presence of detectable bacterial DNA in infected arthroplasty patients before and after successful treatment was also assessed by MRS- and universal PCR. MRS-PCR was positive in 6 patients before treatment and all became negative after a mean interval of 20.8 weeks (95% confidential interval, 13.2 to 33.7) after treatment. Universal PCR detected remnant bacterial DNA in 4 patients at a mean of 15.2 weeks (95% CI, 12.4 to 18.0) after treatment and was negative in 7 patients at a mean of 17.3 weeks (95% CI, 10.6 to 24.0) after treatment. Our studies revealed that real-time PCR detects dead bacteria for several weeks, but this capability decreases with time and is likely lost by 20 weeks after treatment.