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Chirurgiczne aspekty pobierania nerek u swin dla celow ksenotransplantacji

100%

Skucinski J. , Nowak W. , Wieczorek J. , Solecki R.

nr 07

815-818

The number of patients waiting for transplants has increased despite the constant growth of the number of transplants performed. This is the reason why the possibility of using animal organ donors is taken into consideration. Since 2002, the problems concerning xenotrasplantation have been investigated in Poland in the frame of the project: Application of trangenesis in genetic modification of pigs in order to gain organs for transplantation in humans. In the presented paper the possibility of use of transgenic pig kidneys for allogenic and heterogenic transplantation in clinical aspect was evaluated, with the special compliance of surgical methods. The proposed surgical technique of kidney transplantation in pigs derived from the methods used in human medicine and consisted of three stages: the operation of collecting the kidneys en-block, preservation of collected organs and their transplantation. The aim of the first stage was the isolation of the both donor kidneys as fast as possible in a manner not causing the injury of kidney parenchyma, with the maintenance of all anatomical and functional structures and blood vessels. In the study, 3 non-transgenic and 6 transgenic sows with the block of the gene á1,3GT were evaluated. In the presented studies the modification of the routine technique of kidney collection used in human transplantology was performed with the possibility of application of the method for allo- and xenotranplantation in pigs. The maintenance of the defined conditions of perfusion and storage of the collected organs is the requirement of the preservation of viability of the transplant for the time necessary for preparing the organ and the recipient for the transplantation.

Results of integrated geoarchaeological prospection of unique Iron Age hillfort located on Radomno Lake island in north-eastern Poland

88%

Welc F. , Nitychoruk J. , Solecki R. , Rabiega K. , Wysocki J.

tom Vol. 35, Nr 1

55--71

Archaeology of north-eastern Poland has been poorly recognized owing to vast forest areas and numerous lakes. This particularly refers to the Warmian–Masurian Voivodship, where forest covers over 30% of its area. Prospection of forested areas has become possible in Poland just over 10 years ago with the Airborne Laser Scanning (ALS) and Light Detection and Ranging (LiDAR). These techniques allow obtaining 3-D documentation of recognized and also unknown archaeological sites in the forested areas. Thanks to ALS/LiDAR prospection a significant number of archaeological structures have been identified also in the Warmia and Masuria regions. Among them oval-shaped hillforts, surrounded by perfectly spaced concentric moats and ramparts, located mainly on islands and in wetland areas, have raised particular attention. Based on field prospection and results of preliminary excavations, these objects have been considered as Iron Age hillforts. One of the best preserved objects of this type is on the Radomno Lake island, located several kilometres to the south of Iława town. Integrated geoarchaeological prospection of this hillfort emphasized benefits of using LiDAR in combination with results of geophysical prospection and shallow drillings. Applied methodology enabled to document the hillfort shape, and to study its geological structure and stratigraphy. The results clearly indicate that integration of LiDAR data with geophysical prospecting is indispensable in future archaeological surveys. It is a perfect tool for remote sensing of archaeological objects in forest areas, so far not available for traditional archaeology.