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3 Cellular and Molecular Biology Letters

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The dynamic cytoskeleton of the megakaryocyte

100%

Hartwig J. H. , Barkalow K. , Italiano J.

Cellular and Molecular Biology Letters

2001

tom 06

nr 2

The membrane-cytoskeleton interface controls platelet shape change

75%

Hartwig J. H. , Barkalow K. , Azim A. , McGrath J. , Tolias K. , Carpenter C.

Cellular and Molecular Biology Letters

1998

tom 03

nr 4

Platelets respond to stimuli by rapidly changing from discs into active forms having lamellipodia and filopodia. Actin filament fragmentation and assembly are essential for platelet shape change. Actin assembly is regulated by an intracellular signaling pathway that involves calcium and the activation of small GTPases and phosphatidylinositol kinases (PI-kinases). Polyphosphoinositides (ppIs), the final products of the PI-kinases, directly interact with a special class of actin associated proteins, the barbed end capping proteins, to initiate actin filament assembly in activated cells.

The structure of the resting and activated platelet cytoskeleton

63%

Hartwig J. H. , Barkalow K. , Azim A. , Bokoch G. , Ohta Y. , Nakamura S. , Stossel T. , Tolias K. , Carpenter C.

Cellular and Molecular Biology Letters

1998

tom 03

nr 2