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1
Czy istnieje konieczność stosowania antyoksydantów w sporcie?
100%
Dziewiecka H. , Zembron-Lacny A.
Dietetyka. Oficjalne Czasopismo Polskiego Towarzystwa Dietetyki
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2010
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tom 04
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nr 1-2
2
Równowaga prooksydacyjno-antyoksydacyjna u mężczyzn w wieku 30-60 lat uprawiających biegi długodystansowe
80%
Zembron-Lacny A. , Szyszka K. , Sobanska B. , Pakula R.
Aktywność Ruchowa Ludzi w Różnym Wieku
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1998
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tom 03
3
Content available remote Effect of shiitake (Lentinus edodes) extract on antioxidant and inflammatory response to prolonged eccentric exercise
80%
Zembron-Lacny A. , Gajewski M. , Naczk M. , Siatkowski I.
Journal of Physiology and Pharmacology
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2013
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tom 64
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nr 2
4
Content available Exercise tranning-induced changes in inflammatory mediators and heat shock proteins in canoeists
70%
Morawin B. , Rynkiewicz M. , Orysiak J. , Rynkiewicz T. , Zembron-Lacny A.
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nr 4
EN
According to cytokine overtraining theory, skeletal muscle injuries are related to systemic inflammatory reaction. In response to inflammation, cells rapidly produce a series of proteins known as heat shock proteins (HSPs).These are considered to be molecular chaperones which play a universal role in maintaining cellular homeostasis. Among the subset of stress-responsive proteins, HSP27 and HSP70 are considered to be a new approach to monitoring exercise training and adaptive mechanisms. The study was designed to demonstrate the effect of sport training on changes in pro-inflammatory cytokines and HSPs, and their relation with muscle damage and body composition. Six elite canoeists (19.8 ±2.9 yr) were observed during preparatory training period (March) at the 1st, the 4th and after 7 days of the conditioning camp, and then after 3 days of recovery. The canoeing training did not induce muscle damage, decreased in IL-1 ß and HSP27, increased in TNFa and HSP70 concentrations. The highest changes in TNFa and HSP70 were observed 3 days after conditioning camp (during recovery) compared to initial level (the 1st day of conditioning camp). TNFa correlated with HSP27 (r = —0.563; P < 0.01) and HSP70 (r = 0.651; P < 0.001). Any significant changes in body composition were not observed. In conclusion, we could say that typical canoeing training improves cytokines and HSPs release, however, the changes are not related to muscle damage.
5
The role of nitric oxide in skeletal muscle regeneration
70%
Zembron-Lacny A. , Orysiak J. , Kalina K. , Morawin B. , Pokrywka A.
Trends in Sport Sciences
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2013
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tom 20
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nr 4
EN
Essential processes in the regeneration of an injured muscle include proliferation of satellite cells and vascularization. Myogenesis and angiogenesis are prerequisites for the subsequent morphological and functional healing of the injured muscle, leading to the reconstruction of the damaged myocytes and vessels, restoration of the blood fl ow and restoration of the oxygen supply to the tissue. Nitric oxide (NO) plays a key role in satellite cells activation. It acts as a signal molecule and vasodilator, promotes expression genes for many growth factors being extracellular signals regulating the functions of the muscular, vascular and nervous systems. NO is produced by three isoenzymes, called nitric oxide synthases (NOS), present in skeletal muscle. The disturbance equilibrium between eNOS and iNOS activities results in pro-apoptotic NO activity and muscle atrophy. A recent study has shown a relationship between NO generation and delayed onset muscle soreness in response to intense resistance exercise. NO generation can be modulated by physical activity, systemic hypoxia (altitude training) or NO precursors such as L-arginine. The present review provides a current overview of NO effects on skeletal muscles and nutritional strategies based on L-arginine intake to aid muscle regeneration.
6
Content available remote Assessment of the antioxidant effectiveness of alpha-lipoic acid in healthy men exposed to muscle-damaging exercise
61%
Zembron-Lacny A. , Slowinska-Lisowska M. , Szygula Z. , Witkowski K. , Stefaniak T. , Dziubek W.
Journal of Physiology and Pharmacology
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2009
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tom 60
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nr 2
139-143
EN
The aim of this study was to compare the indices of glutathione antioxidant system and oxidative damage level in resistance trained and untrained subjects and to assess the antioxidant action of -lipoic acid in trained men exposed to muscle-damaging exercise. Thirteen trained and twenty untrained men (NT) participated in the comparative study. Then trained men were randomly assigned to TCON group (control) or TALA group (-lipoic acid, 600 mg . day-1, for 8 days) and performed isometric/isokinetic effort of quadriceps muscles. The study has shown the significantly higher erythrocyte levels of glutathione (GSH), glutathione reductase (GR) and glutathione peroxidase (GPx) in TCON than NT but no differences in plasma lipid peroxidation (TBARS) and protein carbonylation (PC). However, total thiol (TT) concentration was two-fold lower in TCON than NT group. -Lipoic acid variously influenced the post-exercise levels of GSH (+40%), GR (-24%) and GPx (+29%), but markedly reduced by over 30% the resting and post-exercise TBARS and PC in TALA compared with TCON. TT concentration significantly increased in TALA but it did not reach the high level which was found in untrained group. It is concluded that -lipoic acid supplementation diminishes oxidative damage. It does not abolish differences in glutathione antioxidant system between untrained and trained subjects but modulates a pro-antioxidant response to the muscle-damaging exercise.
7
Content available remote Metabolic modulators of the exercise response: doping control analysis of an agonist of the peroxisome proliferator-activated receptor delta (GW501516) and 5-aminoimidazole- 4-carboxamide ribonucleotide (AICAR)
61%
Pokrywka A. , Cholbinski P. , Kaliszewski P. , Kowalczyk K. , Konczak D. , Zembron-Lacny A.
Journal of Physiology and Pharmacology
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2014
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tom 65
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nr 4
8
Content available Vitamin D and upper respiratory tract infections in young active males exposed to cold environments
51%
Orysiak J. , Fitzgerald J. S. , Malczewska-Lenczowska J. , Witek K. , Gajewski J. , Zembron-Lacny A. , Morawin B. , Sitkowski D.
Annals of Agricultural and Environmental Medicine
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2021
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tom 28
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nr 3
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