Today, we often apply the intrusion detection to aid the firewall to maintain the network security. But now network intrusion detection have problem of higher false alarm rate, we apply the data warehouse and the data mining in intrusion detection and the technology of network traffic monitoring and analysis. After network data is processed by data mining, we will get the certain data and the uncertain data. Then we process the data by the BP neural network, which based on the genetic algorithm, again. Finally, we propose a new model of intrusion detection based on the data warehouse, the data mining and the BP neural network. The experimental result indicates this model can find effectively many kinds behavior of network intrusion and have higher intelligence and environment accommodation.
PL
Obecnie, w celu utrzymania bezpieczeństwa sieci, stosuje się wykrywanie ataków przy pomocy zapory ogniowej, co często powoduje za wysoki poziom fałszywych ataków. W proponowanym rozwiązaniu proponuje się wykorzystanie magazynowania i pozyskiwania danych oraz analizę monitoringu ruchu sieci. Przetwarzanie danych polegało dotychczas na ustaleniu danych pewnych i niepewnych; obecnie proponujemy wykorzystanie genetycznego algorytmu sieci neuronowych BP. Ostatecznie, wprowadzono nowy model detekcji ataków bazujący na magazynowaniu i pozyskiwaniu danych oraz neuronowych sieciach BP. Badania eksperymentalne wykazują, że zaprezentowany model pozwala na znalezienie wielu rodzajów zachowań ataków sieci, jest bardziej inteligentny, zapewnia wyższy standard obsługi środowiska.
Neuromedin S (NMS), a 36-amino acid neuropeptide, has been found to be involved in the regulation of the endocrine activity. It has been also detected in immune tissues in mammals, what suggests that NMS may play an important role in the regulation of immune response. The aim of this study was to demonstrate the presence of NMS receptor 1 (NMU1R) and effect of NMS in pig splenic lymphocytes (SPLs) and pulmonary alveolar macrophages (PAMs). The presence of NMU1R in pig SPLs and PAMs was respectively confirmed by reverse transcription-polymerase chain reaction (RT-PCR), western blot analysis and immunocytochemical methods. Furthermore, SPL proliferation was analyzed using the 3-(4,5)-dimethyl-thiahiazo-(-2-yl)-3,5-di-phenytetrazoliumromide (MTT) method. Additionally, the secretion of interleukin (IL)-1β, IL-6 and tumor necrosis factor-α (TNF-α) in PAMs was all measured by enzyme-linked immunosorbent assay (ELISA) kits. In the present study, the results of RT-PCR and western blot analysis revealed that NMU1R mRNA and protein were both expressed in pig SPLs and PAMs, and the immunocytochemical investigations further revealed that the positive signal of NMU1R immunoreactivity was observed in plasma membranes of both SPLs and PAMs. In the in vitro study, we found that at concentrations of 0.001-1000 nM NMS alone or combined with lipopolysaccharide or phytohemagglutinin significantly increased SPL proliferation. Application of ELISA method showed that NMS could induce the secretion of the pro-inflammatory cytokines IL-1β, IL-6 and TNF-α in PAMs. These results suggest that NMS can act as a potently positive pro-inflammatory factor and immunomodulatory agent that affects the immune response of immune cells by combining with its receptor NMU1R.