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2 Archivum Immunologiae et Therapiae Experimentalis

2 1992

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HLA-DR antigens in children with mumps meningitis

100%

Matej H. , Kacprzak-Bergman I. , Pacynska J. , Nowakowska B. , Kalamarz M.

Archivum Immunologiae et Therapiae Experimentalis

1992

tom 40

nr 2

117-118

the frequency of HLA-DR antigens was studies in 54 patients with mumps meningitis, and in two control groups. The first control group comprised 333 rondomely chosen subjects while the second group was composed of 46 subjects who have passed mumps without meningitis. The DR5 antigen was more frequent in patients than in the second control group with relative risk of 2,4 and significance at the level of p smaller than 0.05. The p value became insignificant after the correction for the number of antigens investigated.

HLA-A, B, C, and DR gene and haplotype frequencies in 600 poles by a maximum likelihood method of gene counting

86%

Matej H. , Nowakowska B. , Pacynska J. , Kalamarz M. , Baldy-Chudzik K. , Bisikiewicz R.

Archivum Immunologiae et Therapiae Experimentalis

1992

tom 40

nr 2

151-156

A population sample of 600 healthy, unrelated persons was used for estimating HLA-A, B, C and DR antigen. gen, and haplotype frequencies. The Polish population is characterized by a high value of HLA-A10, B13, B27, DR1 and DR5 gene frequencies. Strong gametic associations between genes A1 and B8, A3 and B7, as well as between B8 and DR3, and B7 and DR2, typical for many Europen populations, are also present in the Polish population.