Wyniki wyszukiwania - Biblioteka Nauki

1

Badanie toksyczności tiuramu na szczurach

100%

Piechocka J.

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tom 31

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nr 1

2

Wplyw wybranych fungicydow: tiuramu, kaptanu, kaptafolu i dodyny na aktywnosc izoform cytochromu P-450 1A i 2B w watrobie szczura

80%

Rahden-Staron I. , Szumilo M. , Czeczot H.

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nr 12

179-191

3

Effect of single and repeated administration of thiram on selected adrenocortical function parameters in rats

80%

Osicka-Koprowska A. , Rakoto J.

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tom 05

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nr 2

131-139

4

Zanikanie 3H witaminy D3 z surowicy szczurow narazonych na dzialanie tiuramu

80%

Witkowska D. , Sedrowicz L.

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nr 4

323-329

PL

Zanikanie 3H witaminy D3 w surowicy krwi badano na szczurach samcach szczepu Wistar narażonych na działanie tiuramu przez 2 tygodnie. W oparciu o otwarty model dwukompartmentowy wyznaczono podstawowe parametry farmakokinetyczne, tj. biologiczny okres póltrwania – t0,5, stałe szybkości dystrybucji (k12 i k21) oraz stalą eliminacji (k13).

EN

Male Wistar rats were used to test the effect of 14-day exposure to thiram on 3H vitamin D3 depletion from blood serum. Prior to the experiment, the method (Shepard et al.) of extraction and isolation of vitamin D3 and its metabolites (column chromatography) has been checked and suitably modified. Thiram suspended in soybean oil was administered to rats by stomach intubation at 5% LD50 for 14 days. The controls received similar volume of the oil. After 14 days, the control and thiram-treated rats were injected s.c. with 1 µCi 3H vitamin D3/100 g b.w. The animals were sacrificed 0.5, 1, 2,4, 8, 24 and 48 hours after injection. Blood samples were collected and centrifuged. Each serum sample (0.5 cm3) was extracted with methylene chloride and chromatographed on a column filled with Sephadex LH 20 and porous glass (1:1) to separate 3H vitamin D3 from its metabolites. A hexane- chloroform-methanol 9:1,5:1 mixture was used for elution. Suitable fractions were collected and sample radioactivity was determined using a LKB liquid scintillation spectrometer. The results were expressed in terms of 3H vitamin D3 dpm/1 cm3 serum. The open 2-compartmental model was used in the analysis of the results. Half-life time t, transfer rate constants k13, k21 and the constant of elimination k13 were determined. It has been demonstrated that intoxication with thiram leads to disorders in 3H vitamin D3 elimination from serum. It is reasonable to suppose that thiram may affect vitamin D3 metabolism.

5

Badanie lacznego oddzialywania tiuramu i olowiu na wychwyt przez skrawki dwunastnicy szczura

80%

Witkowska D. , Sedrowicz L. , Oledzka R. , Wojtczak A.

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tom 01

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nr 2

135-140

6

Przyczyny zatruć u drobiu

80%

Duszynska-Stolarska O.

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2015

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nr 2

7

Wplyw tiuramu na osrodkowy uklad nerwowy u szczurow w tescie wielopokoleniowym

80%

Chruscielska K. , Korzeniowski P. , Sitowska B. , Kalhorn D.

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nr 4

331-338

PL

Badanie oddziaływania tiuramu na ośrodkowy układ nerwowy prowadzono na potomstwie trzech pokoleń szczurów w okresie od 1 do 25 dnia życia postnatalnego. Ocenę neurotoksycznego efektu oparto o badania różnych form zachowania oraz oznaczania parametrów neurochemicznych (adrenalina, noradrenalina, dopomina, ceruloplazmina). Dane doświadczalne wskazują, że tiuram w stężeniu 400 mg/kg w paszy podawany szczurom w teście 3-generacji wywołuje zaburzenia funkcjonalne ośrodkowego układu nerwowego u potomstwa badanych pokoleń F1a, F2a oraz, że odchyleniom różnych form behawioru towarzyszą zmiany poziomu neurotransmiterów w tkance mózgowej.

EN

The effect of thiram on the central nervous system of rats was studied in an experiment on three generations (F1, F2, F3) of Wistar rat pups, starting at postnatal days 1 to 25. The neurotoxicological effects were examined by observing different forms of behaviour and determining several neurochemical parameters (adrenaline, noradrenaline, dopamine, ceruloplasmin). The results show that the exposure to dietary thiram at 400 ppm in the 3-generation study caused alterations in the central nervous system of the test pups. The behavioral abnormalities were shown to correlate with the changed neurotranmitter levels in the brain.

8

Zaburzenia neurochemiczne w ustroju szczura przy łącznym oddziaływaniu primoru i tiuramu. Cz.I. Zmiany poziomów amin katecholowych i serotoniny w mózgu, sercu i nadnerczach szczura w warunkach zatrucia ostrego

70%

Biel-Zielinska A. , Brzezinski J.

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nr 2

9

Wplyw diety o zwiekszonej zawartosci witaminy B6 na wchlanianie aminokwasow w jelicie szczurow narazonych na karbaryl,propoksur i tiuram.Cz.1 Metionina

70%

Witkowska D. , Sedrowicz L. , Oledzka R.

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nr 1

25-30

EN

Alimentary rations under test were found to be rich in fat. Fat energy proportional portion exceeded, as a rule, the recommended value by about 30%. At the same time, acidic composition of fat under test was wide of the optimal one. Predominant group was saturated and monounsaturated acids (occurring in similar amounts), however, polyunsaturated acids content amounted to about 11 % of total fatty acids sum. Energy proportional portion from essential fatty acids, in a whole day's rations, was found to be higher than necessary minimum (3%); on the other hand, it did not cover the recommended standard for subjects advanced in years (4%). Value P:S was noted to correspond with an average european diet. Portion of acids with proaggregative properties was higher than hypercholesteremic acids content.

PL

Przeprowadzona ocena wartości żywieniowej tłuszczu wykazała bogatotłuszczowy charakter badanych racji pokarmowych. Dominującą grupę stanowiły kwasy nasycone i jednonienasycone, które występowały w zbliżonych ilościach. Procent energii z NNKT był wyższy od niezbędnego minimum 3%; jednakże nie pokrywał on zalecanej normy dla tej grupy wiekowej.

10

Wpływ zapraw zawierających fludioksonil, karboksynę z tiuramem i tebukonazol na wzrost pszenicy we wczesnych fazach rozwojowych

70%

Kubiak K.

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nr 4

EN

A laboratory experiment was performed on three winter wheat cultivars: Legenda, Sukces and Zyta. Seeds were treated with Maxim 025 FS (fludioxonil), Vitavax 2000 FS (carboxin and thiram) and Zaprawa zbożowa Orius 060 FS (tebuconazole). Treated seeds were incubated for 14 days on Petri dishes in temperature 20°C. The following parameters were evaluated: length and fresh weight of shoot, length and fresh weight of root and number of primary roots. In most cases no significant differences in evaluated winter wheat growth parameters were stated between seed treatments and untreated object. However, some tendencies concerning applied seed treatments could be observed. After the application of seed treatment containing carboxin and thiram (Vitavax 2000 FS) the shoot length on all cultivars was the highest in comparison to untreated object and other seed treatments. The root length and weight was mostly the lowest. After the application of seed treatment containing fludioxonil (Maxim 025 FS) root length on all cultivars was the highest as compared to the other objects. The root weight was lower than in untreated object. The number of primary roots was mostly the lowest in comparison to untreated object and other seed treatments. After the application of seed treatment containing tebuconazole (Zaprawa zbożowa Orius 060 FS) the root weight and number of primary roots of all cultivars was the highest in comparison to untreated object and other seed treatments. The shoot weight was mostly the highest.

11

Wybrane substancje aktywne stosowane w formie zapraw nasiennych w ochronie pszenicy ozimej przed zerowaniem Deroceras reticulatum [Muller]

51%

Kaluski T. , Kozlowski J.

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tom 47

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nr 1

244-248