Wyniki wyszukiwania - Biblioteka Nauki

1

Whipple’s disease as a systemic infectious disease – a case presentation

100%

Maciorkowska M. , Ustymowicz W. , Zakrzewski M. , Pryczynicz A. , Markowski A. , Romatowski J. , Guzińska-Ustymowicz K.

Progress in Health Sciences

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2018

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tom 8(1)

212-218

EN

Introduction: Whipple’s disease is a chronic systemic infectious disorder with Tropheryma whipplei as an etiologic agent, occurring rarely and affecting numerous organs and systems. The variety of symptoms and a non-typical course make it difficult to establish a proper diagnosis. Purpose: In this study, etiopathogenesis, diagnostics and treatment of Whipple’s disease were presented based on the case report of 60-year-old man diagnosed with Whipple’s disease. Case presentation: Persistent diarrhoea with weight loss, lymphadenopathy in the abdominal cavity and moderate microcytic anemia predominated in the clinical picture. Diagnosis was put based on the clinical picture and macroscopic assessment of the small intestine and the presence of macrophages filled with a PAS-positive substance in the lamina propria. To deepen diagnostics, samples collected were assessed showing macrophages with the damaged mucosa, containing numerous elongated micro-organisms whose ultrastructure corresponded to Tropheryma whipplei. The patient’s clinical conditions improved after antibiotic therapy. Conclusions: It is vital to remember about Whipple’s disease in patients with chronic diseases due to a non-specific clinical picture and difficulties in establishing a proper diagnosis. When the disease is diagnosed unequivocally, proper and effective antibiotic therapy should be instituted immediately.

2

Chronic crusting, nasal carriage of Staphylococcus aureus and relapse rate in pulmonary Wegener's granulomatosis

75%

Zycinska K. , Wardyn K. A. , Zielonka T. M. , Demkow U. , Traburzynski M. S.

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nr 6

825-831

3

Stabilized plasmid-lipid particles for systemic gene therapy

75%

Cullis P. R.

Cellular and Molecular Biology Letters

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2002

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tom 07

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nr 2

4

The factors associated with body mass index in adults from the study of health in Pomerania [SHIP-0], Germany

63%

Mack F. , Abeygunawardhana N. , Mundt T. , Schwahn C. , Proff P. , Spassov A. , Kocher T. , Biffar R.

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tom 59

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nr 5

5-16

5

Treatment of systemic diseases by inhalation of biomolecule aerosols

63%

Siekmeier R. , Scheuch G.

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tom 60

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nr 5

6

Cytological picture of the oral mucosa in patients with gastric and colon cancer

63%

Kedra B. , Chomczyk M. , Zlotkowski M. , Stokowska W. , Borsuk A. , Bicz M. , Pietruska M. , Tokajuk G. , Charkiewicz R. , Czajka P. , Chyczewski L. , Zimnoch L. , Kedra B.

Folia Histochemica et Cytobiologica

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2012

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tom 50

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nr 3

7

Vectorial bicarbonate transport by Par-C10 salivary cells

51%

Demeter I. , Szucs A. , Hegyesi O. , Foldes A. , Racz G. Z. , Burghardt B. , Steward M. C. , Varga G.

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tom 60

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nr 7

8

Novel approaches to enhance pulmonary delivery of proteins and peptides

51%

Scheuch G. , Siekmeier R.

Journal of Physiology and Pharmacology. Supplement

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2007

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tom 58

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nr 5

9

Biochemical markers of psoriasis as a metabolic disease

51%

Gerkowicz A. , Pietrzak A. , Szepietowski J. C. , Radej S. , Chodorowska G.

Folia Histochemica et Cytobiologica

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2012

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tom 50

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nr 2

10

Antibody response to inactivated subunit influenza vaccine in patients with Wegener’s granulomatosis

51%

Zycinska K. , Romanowska M. , Nowak I. , Rybicka K. , Wardyn K. A. , Brydak L. B.

Journal of Physiology and Pharmacology. Supplement

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2007

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tom 58

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nr 5

11

Human microbiome: when a friend becomes an enemy

51%

Muszer M. , Noszczynska M. , Kasperkiewicz K. , Skurnik M.

Archivum Immunologiae et Therapiae Experimentalis

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2015

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tom 63

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nr 4

12

Comparative studies on the occurrence of protozoans, bacteria and fungi in the oral cavity of patients with systemic disorders

51%

Chomicz L. , Piekarczyk J. , Starosciak B. , Fiedor P. , Piekarczyk B. , Szubinska D. , Zawadzki P. J. , Walski M.

Acta Parasitologica

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2002

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tom 47

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nr 2

EN

The aim of this study was to compare the oral cavity status with the species composition of microorganisms colonizing the mouth of patients with or without systemic diseases. Seventy-seven men and women, 19 to 65-years-old, of four groups: hemodialyzed patients (HD), kidney allograft recipients (Tx), congenitally disordered (Cd) and control (C) patients (without systemic diseases) were examined clinically for the oral cavity status and the microorganisms occurring in the mouth were identified. Swabs and samples taken from dental plaques, pockets and periodontium were used for light and electron microscopical studies as well as for protozoan, bacterial and fungal cultures. Entamoeba gingivalis and Trichomonas tenax were found in the HD, Tx, Cd and C groups (top prevalence 14, 14, 87.5 and 25%, respectively); free-living amoebae (with some features of Acanthamoeba sp.) also occurred in several cases. Staphylococcus aureus bacteria were found in 66% of Cd patients infected with the protozoans. Numerous fecal bacteria and/or fungi Candida albicans have been observed in 41-51-year-old Cd and HD patients. In all patient groups, it was the 41-51-year-olds who showed the highest prevalence of protozoans, bacteria and fungi. The results indicate that metabolic disabilities favour pathological changes in periodontal tissues and may influence the species composition of mixed protozoan, bacterial and/or fungal infections in various ways, in patients with different systemic diseases.