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An attempt to establish the hierarchy of factors inducing surgical wound infections by means of the rough sets theory

100%

Kandulski M. , Litewka B. , Mrozek A. , Tukallo K.

nr 1

Effect of laser biostimulation on the healing of cutaneous surgical wounds in pigs

84%

Chyczewski M. , Holak P. , Jalynski M. , Kasprowicz A. , Rotkiewicz T. , Mikolajczyk A.

nr 1

135-138

The objective of this study was to investigate the impact of therapeutic laser irradiation on wound healing and skin regeneration in pigs as a supplementary treatment. The experiment was conducted on 32 young pigs divided into four groups: groups I and III served as control, group II comprised pigs with undamaged skin, and group IV consisted of pigs with cutaneous surgical wounds in the dorsal area. Groups II and IV were subjected to laser irradiation. Laser biostimulation was carried out using a CTL 1106 MX semiconductor laser in the continuous wave mode of operation at a wavelength of 810 nm and a maximum output of 100 mW. Following three weeks of observation and clinical skin trials, specimens for a histopathological analysis were collected. The reported results indicate that laser treatment shortens the wound healing process by speeding up the growth of granulation tissue and improving skin elasticity. Laser irradiation of the skin in pigs increases cellular infiltration of the corium and stimulates the proliferation of the stratum germinativum cells of the epidermis. Laser irradiation may be recommended as supplementary therapy in the treatment of surgical wounds.

Effect of laser biostimulation on cell proliferation in the healing of cutaneous surgical wounds in pigs

84%

Chyczewski M. , Rozicka A. , Mikolajczyk A. , Rotkiewicz T. , Holak P. , Jalynski M. , Rotkiewicz Z.

nr 2

217-221

The objective of this study was to investigate the effect of low-level laser therapy (LLLT) on the proliferation of epithelial and connective tissue cells in the healing of incised cutaneous wounds in pigs. The experiment was conducted on 12 young pigs divided into four groups. Group I (undamaged skin) and group III (damaged skin) served as control. Group II - pigs with undamaged skin and group IV - pigs with incised wounds in the dorsal area were subjected to laser irradiation. Laser biostimulation was carried out using a CTL 1106 MX semiconductor laser in the continuous wave mode of operation at a wavelength of 810 nm and a maximum output of 100 mW. Following three weeks of observation, skin specimens were collected for histopathological analysis (HE), immunohistochemical detection of PCNA, and determination of apoptosis (TUNEL) and presence of mast cells (toluidine blue staining). Laser irradiation administered at E=8 J/cm for 1 min over a period of three weeks accelerated the proliferation of stratum basale cells, stimulated fibroblast proliferation, increased the number of mast cells in the wound area, and inhibited apoptosis in cells participating in the skin regeneration process.